{"id":"https://openalex.org/W4319082782","doi":"https://doi.org/10.3390/metabo13020222","title":"Mass-Spectrometry-Based Lipidomics Discriminates Specific Changes in Lipid Classes in Healthy and Dyslipidemic Adults","display_name":"Mass-Spectrometry-Based Lipidomics Discriminates Specific Changes in Lipid Classes in Healthy and Dyslipidemic Adults","publication_year":2023,"publication_date":"2023-02-03","ids":{"openalex":"https://openalex.org/W4319082782","doi":"https://doi.org/10.3390/metabo13020222","pmid":"https://pubmed.ncbi.nlm.nih.gov/36837840","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9964724"},"language":"en","primary_location":{"id":"doi:10.3390/metabo13020222","doi":"https://doi.org/10.3390/metabo13020222","is_oa":true,"landing_page_url":"https://doi.org/10.3390/metabo13020222","pdf_url":"https://www.mdpi.com/2218-1989/13/2/222/pdf?version=1676538412","source":{"id":"https://openalex.org/S2764402194","display_name":"Metabolites","issn_l":"2218-1989","issn":["2218-1989"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolites","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2218-1989/13/2/222/pdf?version=1676538412","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009338555","display_name":"Salvador S\u00e1nchez-Vinces","orcid":"https://orcid.org/0000-0001-7041-6544","observed_orcids":["https://orcid.org/0000-0001-7041-6544"]},"institutions":[{"id":"https://openalex.org/I81009624","display_name":"Universidade S\u00e3o Francisco","ror":"https://ror.org/045ae7j03","country_code":"BR","type":"education","lineage":["https://openalex.org/I81009624"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Salvador S\u00e1nchez-Vinces","raw_affiliation_strings":["Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-7041-6544","affiliations":[{"raw_affiliation_string":"Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil","institution_ids":["https://openalex.org/I81009624"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030497083","display_name":"Pedro Henrique Dias Garcia","orcid":"https://orcid.org/0000-0002-2985-0506","observed_orcids":["https://orcid.org/0000-0002-2985-0506"]},"institutions":[{"id":"https://openalex.org/I81009624","display_name":"Universidade S\u00e3o Francisco","ror":"https://ror.org/045ae7j03","country_code":"BR","type":"education","lineage":["https://openalex.org/I81009624"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Pedro Henrique Dias Garcia","raw_affiliation_strings":["Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil","institution_ids":["https://openalex.org/I81009624"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070553172","display_name":"Alex Silva","orcid":"https://orcid.org/0000-0002-6400-5201","observed_orcids":["https://orcid.org/0000-0002-6400-5201"]},"institutions":[{"id":"https://openalex.org/I81009624","display_name":"Universidade S\u00e3o Francisco","ror":"https://ror.org/045ae7j03","country_code":"BR","type":"education","lineage":["https://openalex.org/I81009624"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Alex Ap. Rosini Silva","raw_affiliation_strings":["Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-6400-5201","affiliations":[{"raw_affiliation_string":"Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil","institution_ids":["https://openalex.org/I81009624"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112413235","display_name":"Anna Maria A. P. Fernandes","orcid":"https://orcid.org/0000-0002-4285-3656","observed_orcids":["https://orcid.org/0000-0002-4285-3656"]},"institutions":[{"id":"https://openalex.org/I81009624","display_name":"Universidade S\u00e3o Francisco","ror":"https://ror.org/045ae7j03","country_code":"BR","type":"education","lineage":["https://openalex.org/I81009624"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Anna Maria Alves de Piloto Fernandes","raw_affiliation_strings":["Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil","institution_ids":["https://openalex.org/I81009624"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050183494","display_name":"Joyce Aparecida Barreto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210092160","display_name":"Unidade Integrada de Farmacologia e Gastroenterologia","ror":"https://ror.org/00fwp4v27","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210092160"]},{"id":"https://openalex.org/I81009624","display_name":"Universidade S\u00e3o Francisco","ror":"https://ror.org/045ae7j03","country_code":"BR","type":"education","lineage":["https://openalex.org/I81009624"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Joyce Aparecida Barreto","raw_affiliation_strings":["Integrated Unit of Pharmacology and Gastroenterology (UNIFAG), S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Integrated Unit of Pharmacology and Gastroenterology (UNIFAG), S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil","institution_ids":["https://openalex.org/I4210092160","https://openalex.org/I81009624"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064382539","display_name":"Gustavo Henrique Bueno Duarte","orcid":"https://orcid.org/0000-0003-0261-9934","observed_orcids":["https://orcid.org/0000-0003-0261-9934"]},"institutions":[{"id":"https://openalex.org/I81009624","display_name":"Universidade S\u00e3o Francisco","ror":"https://ror.org/045ae7j03","country_code":"BR","type":"education","lineage":["https://openalex.org/I81009624"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gustavo Henrique Bueno Duarte","raw_affiliation_strings":["Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil","institution_ids":["https://openalex.org/I81009624"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015458137","display_name":"M\u00e1rcia Aparecida Ant\u00f4nio","orcid":"https://orcid.org/0000-0002-3239-509X","observed_orcids":["https://orcid.org/0000-0002-3239-509X"]},"institutions":[{"id":"https://openalex.org/I4210092160","display_name":"Unidade Integrada de Farmacologia e Gastroenterologia","ror":"https://ror.org/00fwp4v27","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210092160"]},{"id":"https://openalex.org/I81009624","display_name":"Universidade S\u00e3o Francisco","ror":"https://ror.org/045ae7j03","country_code":"BR","type":"education","lineage":["https://openalex.org/I81009624"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marcia Aparecida Antonio","raw_affiliation_strings":["Integrated Unit of Pharmacology and Gastroenterology (UNIFAG), S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-3239-509X","affiliations":[{"raw_affiliation_string":"Integrated Unit of Pharmacology and Gastroenterology (UNIFAG), S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil","institution_ids":["https://openalex.org/I4210092160","https://openalex.org/I81009624"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067988005","display_name":"Alexander Birbrair","orcid":"https://orcid.org/0000-0003-1015-2561","observed_orcids":["https://orcid.org/0000-0003-1015-2561"]},"institutions":[{"id":"https://openalex.org/I110200422","display_name":"Universidade Federal de Minas Gerais","ror":"https://ror.org/0176yjw32","country_code":"BR","type":"education","lineage":["https://openalex.org/I110200422"]},{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["BR","US"],"is_corresponding":false,"raw_author_name":"Alexander Birbrair","raw_affiliation_strings":["Department of Dermatology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53715-1149, USA","Department of Pathology, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil","Department of Radiology, Columbia University Medical Center, New York, NY 10032, USA"],"raw_orcid":"https://orcid.org/0000-0003-1015-2561","affiliations":[{"raw_affiliation_string":"Department of Dermatology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53715-1149, USA","institution_ids":["https://openalex.org/I135310074"]},{"raw_affiliation_string":"Department of Pathology, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil","institution_ids":["https://openalex.org/I110200422"]},{"raw_affiliation_string":"Department of Radiology, Columbia University Medical Center, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023723367","display_name":"Andr\u00e9ia M. Porcari","orcid":"https://orcid.org/0000-0003-4244-8594","observed_orcids":["https://orcid.org/0000-0003-4244-8594"]},"institutions":[{"id":"https://openalex.org/I81009624","display_name":"Universidade S\u00e3o Francisco","ror":"https://ror.org/045ae7j03","country_code":"BR","type":"education","lineage":["https://openalex.org/I81009624"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Andreia M. Porcari","raw_affiliation_strings":["Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-4244-8594","affiliations":[{"raw_affiliation_string":"Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil","institution_ids":["https://openalex.org/I81009624"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032383389","display_name":"Patr\u00edcia de Oliveira Carvalho","orcid":"https://orcid.org/0000-0002-2681-7022","observed_orcids":["https://orcid.org/0000-0002-2681-7022"]},"institutions":[{"id":"https://openalex.org/I81009624","display_name":"Universidade S\u00e3o Francisco","ror":"https://ror.org/045ae7j03","country_code":"BR","type":"education","lineage":["https://openalex.org/I81009624"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Patricia de Oliveira Carvalho","raw_affiliation_strings":["Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-2681-7022","affiliations":[{"raw_affiliation_string":"Health Sciences Postgraduate Program, S\u00e3o Francisco University\u2013USF, Bragan\u00e7a Paulista 12900-000, SP, Brazil","institution_ids":["https://openalex.org/I81009624"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5032383389"],"corresponding_institution_ids":["https://openalex.org/I81009624"],"apc_list":{"value":2200,"currency":"CHF","value_usd":2447},"apc_paid":{"value":2200,"currency":"CHF","value_usd":2447},"fwci":0.6674,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.59554423,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"13","issue":"2","first_page":"222","last_page":"222"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.006599999964237213,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipidomics","display_name":"lipidomics","score":0.925000011920929},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9449999928474426},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.8949999809265137},{"id":"https://openalex.org/keywords/hypertriglyceridemia","display_name":"hypertriglyceridemia","score":0.9229999780654907},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mixed-dyslipidemia","display_name":"mixed dyslipidemia","score":0.9549999833106995},{"id":"https://openalex.org/keywords/ceramide","display_name":"ceramide","score":0.781000018119812},{"id":"https://openalex.org/keywords/sphingomyelin","display_name":"sphingomyelin","score":0.996999979019165},{"id":"https://openalex.org/keywords/glycerophosphocholine","display_name":"glycerophosphocholine","score":0.9039999842643738},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.7910000085830688},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.9980000257492065},{"id":"https://openalex.org/keywords/lipidomic-signatures","display_name":"lipidomic signatures","score":0.6029999852180481},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.9039999842643738}],"concepts":[{"id":"https://openalex.org/C58017582","wikidata":"https://www.wikidata.org/wiki/Q6556376","display_name":"Lipidomics","level":2,"score":0.8922514915466309},{"id":"https://openalex.org/C2780241833","wikidata":"https://www.wikidata.org/wiki/Q6556375","display_name":"Lipidome","level":3,"score":0.8679987192153931},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.7897701263427734},{"id":"https://openalex.org/C61322309","wikidata":"https://www.wikidata.org/wiki/Q423143","display_name":"Sphingomyelin","level":3,"score":0.6244328618049622},{"id":"https://openalex.org/C2776919658","wikidata":"https://www.wikidata.org/wiki/Q1467339","display_name":"Hypertriglyceridemia","level":4,"score":0.5606456995010376},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.5266447067260742},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.524527370929718},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.5207622051239014},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.5072774291038513},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5035244822502136},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4467860460281372},{"id":"https://openalex.org/C139572402","wikidata":"https://www.wikidata.org/wiki/Q4927820","display_name":"Blood lipids","level":3,"score":0.4427626132965088},{"id":"https://openalex.org/C2780541478","wikidata":"https://www.wikidata.org/wiki/Q410020","display_name":"High-density lipoprotein","level":3,"score":0.4164663553237915},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.34580525755882263},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.32117530703544617},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27373194694519043},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23875170946121216},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.14715254306793213}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/metabo13020222","doi":"https://doi.org/10.3390/metabo13020222","is_oa":true,"landing_page_url":"https://doi.org/10.3390/metabo13020222","pdf_url":"https://www.mdpi.com/2218-1989/13/2/222/pdf?version=1676538412","source":{"id":"https://openalex.org/S2764402194","display_name":"Metabolites","issn_l":"2218-1989","issn":["2218-1989"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolites","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9964724","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9964724","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9964724/pdf/metabolites-13-00222.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolites","raw_type":"Text"},{"id":"pmid:36837840","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36837840","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolites","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:a7030417a82d491b85d3020fd41d44c8","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a7030417a82d491b85d3020fd41d44c8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Metabolites, Vol 13, Iss 2, p 222 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/metabo13020222","doi":"https://doi.org/10.3390/metabo13020222","is_oa":true,"landing_page_url":"https://doi.org/10.3390/metabo13020222","pdf_url":"https://www.mdpi.com/2218-1989/13/2/222/pdf?version=1676538412","source":{"id":"https://openalex.org/S2764402194","display_name":"Metabolites","issn_l":"2218-1989","issn":["2218-1989"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolites","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2228771037","display_name":"A lipidomics study applied to Rectal Cancer: biochemical-molecular mechanisms and assessment of the response to neoadjuvant therapy","funder_award_id":"18/13317-6","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G5601649697","display_name":null,"funder_award_id":"2020/11461-2","funder_id":"https://openalex.org/F4320321091","funder_display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior"},{"id":"https://openalex.org/G7974285255","display_name":null,"funder_award_id":"2020/11461-2","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"}],"funders":[{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4319082782.pdf","grobid_xml":"https://content.openalex.org/works/W4319082782.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1240353884","https://openalex.org/W1990679071","https://openalex.org/W2001157090","https://openalex.org/W2017602185","https://openalex.org/W2044318948","https://openalex.org/W2068700927","https://openalex.org/W2070690965","https://openalex.org/W2093824918","https://openalex.org/W2096769282","https://openalex.org/W2111416524","https://openalex.org/W2116404316","https://openalex.org/W2122248435","https://openalex.org/W2136024338","https://openalex.org/W2145813488","https://openalex.org/W2146512944","https://openalex.org/W2191517812","https://openalex.org/W2317020250","https://openalex.org/W2534785935","https://openalex.org/W2607572215","https://openalex.org/W2738994915","https://openalex.org/W2788261792","https://openalex.org/W2792381506","https://openalex.org/W2885749386","https://openalex.org/W2913413642","https://openalex.org/W3003573827","https://openalex.org/W3020683783","https://openalex.org/W3022658502","https://openalex.org/W3037136069","https://openalex.org/W3082469865","https://openalex.org/W3091953196","https://openalex.org/W3092477646","https://openalex.org/W3095580505","https://openalex.org/W3112003111","https://openalex.org/W3120969926","https://openalex.org/W3162063228","https://openalex.org/W3183498184","https://openalex.org/W3185687330","https://openalex.org/W3186643282","https://openalex.org/W3197326839","https://openalex.org/W3205422331","https://openalex.org/W3217198834","https://openalex.org/W4206447491","https://openalex.org/W4225258286"],"related_works":["https://openalex.org/W6977580992","https://openalex.org/W2924428359","https://openalex.org/W2922525161","https://openalex.org/W4396641685","https://openalex.org/W1994147438","https://openalex.org/W7135204485","https://openalex.org/W2169544819","https://openalex.org/W2023808849","https://openalex.org/W2781483823","https://openalex.org/W1987064503"],"abstract_inverted_index":{"Triacylglycerols":[0],"(TAGs)":[1],"and":[2,13,59,81,100,120,136,171,174],"cholesterol":[3,137],"lipoprotein":[4,138],"levels":[5,139,156,184],"are":[6,185],"widely":[7],"used":[8,128],"to":[9,22,38,67,112,129],"predict":[10,130],"cardiovascular":[11],"risk":[12],"metabolic":[14],"disorders.":[15],"The":[16,49],"aim":[17],"of":[18,43,56,117,133,143,152,157,166,191],"this":[19],"study":[20,50],"is":[21,36],"determine":[23,113],"how":[24],"the":[25,39,114,131,141,144,150,167],"comprehensive":[26],"lipidome":[27],"(individual":[28],"molecular":[29],"lipid":[30,69],"species)":[31],"determined":[32],"by":[33],"mass":[34,106],"spectrometry":[35,107],"correlated":[37,187],"serum":[40,134],"whole-lipidic":[41],"profile":[42],"adults":[44,55,159],"with":[45,140,164,178,188,201],"different":[46],"lipidemic":[47],"conditions.":[48],"included":[51],"samples":[52],"from":[53],"128":[54],"both":[57],"sexes,":[58],"they":[60],"were":[61],"separated":[62],"into":[63],"four":[64],"groups":[65,190],"according":[66],"their":[68],"profile:":[70],"Group":[71,86,93,101],"I-normolipidemic":[72],"(TAG":[73,89],"<":[74,78],"150":[75,91],"mg/dL,":[76],"LDL-C":[77],"160":[79,98],"mg/dL":[80],"HDL-c":[82],">":[83],"40":[84],"mg/dL);":[85,92],"II-isolated":[87],"hypertriglyceridemia":[88],"\u2265":[90,97],"III-isolated":[94],"hypercholesterolemia":[95],"(LDL-C":[96],"mg/dL)":[99],"IV-mixed":[102],"dyslipidemia.":[103],"An":[104],"untargeted":[105],"(MS)-based":[108],"approach":[109],"was":[110,127],"applied":[111],"lipidomic":[115],"signature":[116],"32":[118],"healthy":[119],"96":[121],"dyslipidemic":[122,158],"adults.":[123],"Limma":[124],"linear":[125],"regression":[126],"correlation":[132,163,177,200],"TAGs":[135,170],"abundance":[142],"identified":[145],"MS-annotated":[146,168],"lipids":[147],"found":[148],"in":[149],"subgroups":[151],"subjects.":[153],"Serum":[154],"TAG":[155],"have":[160],"a":[161,175,198],"positive":[162,199],"some":[165,189],"specific":[169],"ceramides":[172],"(Cer)":[173],"negative":[176],"sphingomyelins":[179],"(SMs).":[180],"High-density":[181],"lipoprotein-cholesterol":[182,195],"(HDL-C)":[183],"positively":[186],"glycerophosphocholine,":[192],"while":[193],"low-density":[194],"(LDL-C)":[196],"has":[197],"SMs.":[202]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-02-04T00:00:00"}