{"id":"https://openalex.org/W4319082411","doi":"https://doi.org/10.3390/biology12020239","title":"Overexpression of E-Cadherin Is a Favorable Prognostic Biomarker in Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis","display_name":"Overexpression of E-Cadherin Is a Favorable Prognostic Biomarker in Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis","publication_year":2023,"publication_date":"2023-02-02","ids":{"openalex":"https://openalex.org/W4319082411","doi":"https://doi.org/10.3390/biology12020239","pmid":"https://pubmed.ncbi.nlm.nih.gov/36829516","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9953277"},"language":"en","primary_location":{"id":"doi:10.3390/biology12020239","doi":"https://doi.org/10.3390/biology12020239","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biology12020239","pdf_url":"https://www.mdpi.com/2079-7737/12/2/239/pdf?version=1676452866","source":{"id":"https://openalex.org/S153489431","display_name":"Biology","issn_l":"2079-7737","issn":["2079-7737"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2079-7737/12/2/239/pdf?version=1676452866","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051877765","display_name":"Alejandro I. Lorenzo\u2010Pouso","orcid":"https://orcid.org/0000-0002-9180-4703","observed_orcids":["https://orcid.org/0000-0002-9180-4703"]},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Alejandro I. Lorenzo-Pouso","raw_affiliation_strings":["Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"],"raw_orcid":"https://orcid.org/0000-0002-9180-4703","affiliations":[{"raw_affiliation_string":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046183018","display_name":"F\u00e1bio Fran\u00e7a Vieira e Silva","orcid":"https://orcid.org/0000-0001-8389-086X","observed_orcids":["https://orcid.org/0000-0001-8389-086X"]},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"F\u00e1bio Fran\u00e7a-Vieira e Silva","raw_affiliation_strings":["ORALRES Group, Health Research Institute of Santiago de Compostela (FIDIS), 15782 Santiago de Compostela, Spain","Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"],"raw_orcid":"https://orcid.org/0000-0001-8389-086X","affiliations":[{"raw_affiliation_string":"ORALRES Group, Health Research Institute of Santiago de Compostela (FIDIS), 15782 Santiago de Compostela, Spain","institution_ids":[]},{"raw_affiliation_string":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043734775","display_name":"Alba P\u00e9rez Jard\u00f3n","orcid":"https://orcid.org/0000-0001-5174-8922","observed_orcids":["https://orcid.org/0000-0001-5174-8922"]},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Alba P\u00e9rez-Jard\u00f3n","raw_affiliation_strings":["ORALRES Group, Health Research Institute of Santiago de Compostela (FIDIS), 15782 Santiago de Compostela, Spain","Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"],"raw_orcid":"https://orcid.org/0000-0001-5174-8922","affiliations":[{"raw_affiliation_string":"ORALRES Group, Health Research Institute of Santiago de Compostela (FIDIS), 15782 Santiago de Compostela, Spain","institution_ids":[]},{"raw_affiliation_string":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001783310","display_name":"Cintia Micaela Chamorro-Petronacci","orcid":"https://orcid.org/0000-0002-5637-9908","observed_orcids":["https://orcid.org/0000-0002-5637-9908"]},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Cintia M. Chamorro-Petronacci","raw_affiliation_strings":["ORALRES Group, Health Research Institute of Santiago de Compostela (FIDIS), 15782 Santiago de Compostela, Spain","Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"],"raw_orcid":"https://orcid.org/0000-0002-5637-9908","affiliations":[{"raw_affiliation_string":"ORALRES Group, Health Research Institute of Santiago de Compostela (FIDIS), 15782 Santiago de Compostela, Spain","institution_ids":[]},{"raw_affiliation_string":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057947618","display_name":"M\u00f4nica Ghislaine Oliveira Alves","orcid":"https://orcid.org/0000-0002-3411-9443","observed_orcids":["https://orcid.org/0000-0002-3411-9443"]},"institutions":[{"id":"https://openalex.org/I184779318","display_name":"Anhembi Morumbi University","ror":"https://ror.org/00ay50243","country_code":"BR","type":"education","lineage":["https://openalex.org/I184779318"]},{"id":"https://openalex.org/I98496276","display_name":"Universidade de Mogi das Cruzes","ror":"https://ror.org/04hnrs676","country_code":"BR","type":"education","lineage":["https://openalex.org/I98496276"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"M\u00f4nica G. Oliveira-Alves","raw_affiliation_strings":["School of Medicine, Anhembi Morumbi University, S\u00e3o Jos\u00e9 dos Campos 12247-004, SP, Brazil","Technology Research Center (NPT), Universidade Mogi das Cruzes, Mogi das Cruzes 12245-000, SP, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-3411-9443","affiliations":[{"raw_affiliation_string":"School of Medicine, Anhembi Morumbi University, S\u00e3o Jos\u00e9 dos Campos 12247-004, SP, Brazil","institution_ids":["https://openalex.org/I184779318"]},{"raw_affiliation_string":"Technology Research Center (NPT), Universidade Mogi das Cruzes, Mogi das Cruzes 12245-000, SP, Brazil","institution_ids":["https://openalex.org/I98496276"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018643418","display_name":"\u00d3scar \u00c1lvarez-Calder\u00f3n-Iglesias","orcid":"https://orcid.org/0000-0002-1104-6894","observed_orcids":["https://orcid.org/0000-0002-1104-6894"]},"institutions":[{"id":"https://openalex.org/I11019714","display_name":"Universidade da Coru\u00f1a","ror":"https://ror.org/01qckj285","country_code":"ES","type":"education","lineage":["https://openalex.org/I11019714"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"\u00d3scar \u00c1lvarez-Calder\u00f3n-Iglesias","raw_affiliation_strings":["HM Hospitals Research Foundation, 28015 Madrid, Spain","Research, Health and Podiatry Group, Department of Health Sciences, Faculty of Nursing and Podiatry, University of A Corun\u0303a, 15008 A Corun\u0303a, Spain"],"raw_orcid":"https://orcid.org/0000-0002-1104-6894","affiliations":[{"raw_affiliation_string":"HM Hospitals Research Foundation, 28015 Madrid, Spain","institution_ids":[]},{"raw_affiliation_string":"Research, Health and Podiatry Group, Department of Health Sciences, Faculty of Nursing and Podiatry, University of A Corun\u0303a, 15008 A Corun\u0303a, Spain","institution_ids":["https://openalex.org/I11019714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071101838","display_name":"Vito Carlo Alberto Caponio","orcid":"https://orcid.org/0000-0001-5080-5921","observed_orcids":["https://orcid.org/0000-0001-5080-5921"]},"institutions":[{"id":"https://openalex.org/I106296451","display_name":"University of Foggia","ror":"https://ror.org/01xtv3204","country_code":"IT","type":"education","lineage":["https://openalex.org/I106296451"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Vito Carlo Alberto Caponio","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy"],"raw_orcid":"https://orcid.org/0000-0001-5080-5921","affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy","institution_ids":["https://openalex.org/I106296451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081715106","display_name":"Morena Pinti","orcid":"https://orcid.org/0009-0002-2037-1063","observed_orcids":["https://orcid.org/0009-0002-2037-1063"]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Morena Pinti","raw_affiliation_strings":["Department of Medical, Oral and Biotechnological Sciences, University \u201cG. d\u2019Annunzio\u201d Chieti-Pescara, 66100 Chieti, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical, Oral and Biotechnological Sciences, University \u201cG. d\u2019Annunzio\u201d Chieti-Pescara, 66100 Chieti, Italy","institution_ids":["https://openalex.org/I39387349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076022518","display_name":"Vittoria Perrotti","orcid":"https://orcid.org/0000-0001-7652-1660","observed_orcids":["https://orcid.org/0000-0001-7652-1660"]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Vittoria Perrotti","raw_affiliation_strings":["Department of Medical, Oral and Biotechnological Sciences, University \u201cG. d\u2019Annunzio\u201d Chieti-Pescara, 66100 Chieti, Italy"],"raw_orcid":"https://orcid.org/0000-0001-7652-1660","affiliations":[{"raw_affiliation_string":"Department of Medical, Oral and Biotechnological Sciences, University \u201cG. d\u2019Annunzio\u201d Chieti-Pescara, 66100 Chieti, Italy","institution_ids":["https://openalex.org/I39387349"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007229564","display_name":"M\u00e1rio P\u00e9rez\u2010Say\u00e1ns","orcid":"https://orcid.org/0000-0003-2196-9868","observed_orcids":["https://orcid.org/0000-0003-2196-9868"]},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Mario P\u00e9rez-Say\u00e1ns","raw_affiliation_strings":["ORALRES Group, Health Research Institute of Santiago de Compostela (FIDIS), 15782 Santiago de Compostela, Spain","Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"],"raw_orcid":"https://orcid.org/0000-0003-2196-9868","affiliations":[{"raw_affiliation_string":"ORALRES Group, Health Research Institute of Santiago de Compostela (FIDIS), 15782 Santiago de Compostela, Spain","institution_ids":[]},{"raw_affiliation_string":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes), Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5071101838"],"corresponding_institution_ids":["https://openalex.org/I106296451"],"apc_list":{"value":2200,"currency":"CHF","value_usd":2447},"apc_paid":{"value":2200,"currency":"CHF","value_usd":2447},"fwci":1.3856,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.83478261,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"12","issue":"2","first_page":"239","last_page":"239"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11452","display_name":"Oral Health Pathology and Treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/e-cadherin","display_name":"E-cadherin","score":0.9769999980926514},{"id":"https://openalex.org/keywords/oral-squamous-cell-carcinoma","display_name":"oral squamous cell carcinoma","score":0.9980000257492065},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9959999918937683},{"id":"https://openalex.org/keywords/cell-adhesion-molecules","display_name":"adhesion molecules","score":0.7329999804496765},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.8980000019073486},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":1.0},{"id":"https://openalex.org/keywords/tongue-cancer","display_name":"tongue cancer","score":0.9829999804496765},{"id":"https://openalex.org/keywords/immunohistochemistry","display_name":"immunohistochemistry","score":0.7239999771118164},{"id":"https://openalex.org/keywords/tumor-invasion","display_name":"tumor invasion","score":0.6010000109672546}],"concepts":[{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6777315139770508},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6338924169540405},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6224187612533569},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5954667925834656},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.5888886451721191},{"id":"https://openalex.org/C149402561","wikidata":"https://www.wikidata.org/wiki/Q24776048","display_name":"Cadherin","level":3,"score":0.564306914806366},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.497913122177124},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.4808293581008911},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.47288957238197327},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.46149003505706787},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.43852078914642334},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.4197564125061035},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3745947480201721},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2688975930213928},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.19794440269470215},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.17335271835327148},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07066231966018677}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3390/biology12020239","doi":"https://doi.org/10.3390/biology12020239","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biology12020239","pdf_url":"https://www.mdpi.com/2079-7737/12/2/239/pdf?version=1676452866","source":{"id":"https://openalex.org/S153489431","display_name":"Biology","issn_l":"2079-7737","issn":["2079-7737"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9953277","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9953277","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9953277/pdf/biology-12-00239.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology (Basel)","raw_type":"Text"},{"id":"pmid:36829516","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36829516","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology","raw_type":"Journal Article"},{"id":"pmh:oai:runa.sergas.gal:20.500.11940/21823","doi":null,"is_oa":true,"landing_page_url":"https://portalcientifico.sergas.gal//documentos/647346e5c0b3b13849988665","pdf_url":"https://runa.sergas.gal/xmlui/bitstream/20.500.11940/21823/1/2130.pdf","source":{"id":"https://openalex.org/S4306402506","display_name":"RUNA. Repositorio Institucional del Sergas (Servicio Gallego de Salud (SERGAS))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210158352","host_organization_name":"Servicio Gallego de Salud","host_organization_lineage":["https://openalex.org/I4210158352"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:013e6cce19d84bb79daf13f7179ca015","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/013e6cce19d84bb79daf13f7179ca015","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biology, Vol 12, Iss 2, p 239 (2023)","raw_type":"article"},{"id":"pmh:oai:ruc.udc.es:2183/32920","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2183/32920","pdf_url":null,"source":{"id":"https://openalex.org/S4306402204","display_name":"RUC (Universidade Da Coru\u00f1a)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I11019714","host_organization_name":"Universidade da Coru\u00f1a","host_organization_lineage":["https://openalex.org/I11019714"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3390/biology12020239","doi":"https://doi.org/10.3390/biology12020239","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biology12020239","pdf_url":"https://www.mdpi.com/2079-7737/12/2/239/pdf?version=1676452866","source":{"id":"https://openalex.org/S153489431","display_name":"Biology","issn_l":"2079-7737","issn":["2079-7737"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[{"id":"https://openalex.org/G2981336808","display_name":null,"funder_award_id":"IDIS2020/PREDOC/03","funder_id":"https://openalex.org/F4320317209","funder_display_name":"Fundaci\u00f3n Instituto de Investigaci\u00f3n Sanitaria de Santiago de Compostela"}],"funders":[{"id":"https://openalex.org/F4320317209","display_name":"Fundaci\u00f3n Instituto de Investigaci\u00f3n Sanitaria de Santiago de Compostela","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4319082411.pdf","grobid_xml":"https://content.openalex.org/works/W4319082411.grobid-xml"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W1515566746","https://openalex.org/W1519375111","https://openalex.org/W1926654776","https://openalex.org/W1966241991","https://openalex.org/W1969511542","https://openalex.org/W1971872239","https://openalex.org/W1979423827","https://openalex.org/W1989240437","https://openalex.org/W1992270036","https://openalex.org/W1994633840","https://openalex.org/W1997026098","https://openalex.org/W1997629949","https://openalex.org/W2014128353","https://openalex.org/W2027091383","https://openalex.org/W2027200362","https://openalex.org/W2027518405","https://openalex.org/W2027858199","https://openalex.org/W2031400410","https://openalex.org/W2033871653","https://openalex.org/W2036832661","https://openalex.org/W2048067731","https://openalex.org/W2048994014","https://openalex.org/W2052743504","https://openalex.org/W2064514125","https://openalex.org/W2066972686","https://openalex.org/W2074783659","https://openalex.org/W2075642745","https://openalex.org/W2079622666","https://openalex.org/W2083465490","https://openalex.org/W2088095316","https://openalex.org/W2088130063","https://openalex.org/W2089028882","https://openalex.org/W2102587762","https://openalex.org/W2102877711","https://openalex.org/W2115124950","https://openalex.org/W2122992925","https://openalex.org/W2125120607","https://openalex.org/W2125435699","https://openalex.org/W2129686681","https://openalex.org/W2136130863","https://openalex.org/W2140551998","https://openalex.org/W2147083039","https://openalex.org/W2419405591","https://openalex.org/W2535284666","https://openalex.org/W2547048777","https://openalex.org/W2588681363","https://openalex.org/W2741450739","https://openalex.org/W2766078810","https://openalex.org/W2783337717","https://openalex.org/W2810690360","https://openalex.org/W2883534738","https://openalex.org/W2892273598","https://openalex.org/W2951988944","https://openalex.org/W2970614447","https://openalex.org/W3031331065","https://openalex.org/W3042355462","https://openalex.org/W3093303864","https://openalex.org/W3100636987","https://openalex.org/W3118615836","https://openalex.org/W3122988797","https://openalex.org/W3158974490"],"related_works":["https://openalex.org/W1989481111","https://openalex.org/W3196801426","https://openalex.org/W2171221682","https://openalex.org/W2053880449","https://openalex.org/W4226107127","https://openalex.org/W2319118817","https://openalex.org/W2048994014","https://openalex.org/W2023237882","https://openalex.org/W2098166113","https://openalex.org/W1967464224"],"abstract_inverted_index":{"Oral":[0],"squamous":[1],"cell":[2,46],"carcinoma":[3],"(OSCC)":[4],"is":[5,26],"characterized":[6],"by":[7],"poor":[8],"survival,":[9],"mostly":[10],"due":[11],"to":[12,56,96],"local":[13],"invasion,":[14],"loco-regional":[15],"recurrence,":[16],"and":[17,33,84,90,139,189],"metastasis.":[18],"Given":[19],"that":[20],"the":[21,31,42,65,106,178,182,199],"weakening":[22],"of":[23,35,45,68,80,111,153,181,185],"cell-to-cell":[24],"adhesion":[25,47],"a":[27,61,109,194],"feature":[28],"associated":[29,118],"with":[30,119,124,142,156,165],"migration":[32],"invasion":[34],"cancer":[36,158],"cells,":[37],"different":[38,195],"studies":[39,74],"have":[40],"explored":[41],"prognostic":[43,66,179],"utility":[44],"molecules":[48],"such":[49],"as":[50],"E-cadherin":[51],"(E-cad).":[52],"This":[53],"study":[54],"aims":[55],"summarize":[57],"current":[58],"evidence":[59],"in":[60,70,105,187],"meta-analysis,":[62,107],"focusing":[63],"on":[64,198],"role":[67,180,196],"E-cad":[69,114,164,186],"OSCC.":[71],"To":[72],"find":[73],"meeting":[75],"inclusion":[76,104],"criteria,":[77],"Scopus,":[78],"Web":[79],"Science,":[81],"EMBASE,":[82],"Medline,":[83],"OpenGrey":[85],"databases":[86],"were":[87,100],"systematically":[88],"assessed":[89],"screened.":[91],"The":[92],"selection":[93],"process":[94],"led":[95],"25":[97],"studies,":[98],"which":[99],"considered":[101],"eligible":[102],"for":[103],"representing":[108],"sample":[110],"2553":[112],"patients.":[113],"overexpression":[115],"was":[116],"strongly":[117],"longer":[120],"overall":[121],"survival":[122,141],"(OS)":[123],"Hazard":[125],"Ratio":[126],"(HR)":[127],"=":[128],"0.41":[129],"95%":[130,145,168],"confidence":[131],"interval":[132],"(95%":[133],"CI)":[134],"(0.32\u20130.54);":[135],"p":[136,148,171],"<":[137,149,172],"0.001":[138],"disease-free":[140],"HR":[143,166],"0.47":[144],"CI":[146,169],"(0.37\u20130.61);":[147],"0.001.":[150,173],"In":[151],"terms":[152],"OS,":[154],"patients":[155],"tongue":[157],"experienced":[159],"better":[160],"survivability":[161],"when":[162],"expressing":[163],"0.28":[167],"(0.19\u20130.43);":[170],"Globally,":[174],"our":[175],"findings":[176],"indicate":[177],"immunohistochemical":[183],"assessment":[184],"OSCC":[188],"its":[190],"expression":[191],"might":[192],"acquire":[193],"based":[197],"oral":[200],"cavity":[201],"subsites.":[202]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":6}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2023-02-04T00:00:00"}