{"id":"https://openalex.org/W4319081990","doi":"https://doi.org/10.3390/antibiotics12020318","title":"Impact of COVID-19 Pandemic in Antibiotic Consumption in Navarre (Spain): An Interrupted Time Series Analysis","display_name":"Impact of COVID-19 Pandemic in Antibiotic Consumption in Navarre (Spain): An Interrupted Time Series Analysis","publication_year":2023,"publication_date":"2023-02-03","ids":{"openalex":"https://openalex.org/W4319081990","doi":"https://doi.org/10.3390/antibiotics12020318","pmid":"https://pubmed.ncbi.nlm.nih.gov/36830228","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9952456"},"language":"en","primary_location":{"id":"doi:10.3390/antibiotics12020318","doi":"https://doi.org/10.3390/antibiotics12020318","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antibiotics12020318","pdf_url":"https://www.mdpi.com/2079-6382/12/2/318/pdf?version=1675399614","source":{"id":"https://openalex.org/S2736332253","display_name":"Antibiotics","issn_l":"2079-6382","issn":["2079-6382"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antibiotics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2079-6382/12/2/318/pdf?version=1675399614","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008025853","display_name":"Natalia Alzueta","orcid":"https://orcid.org/0000-0002-8513-239X","observed_orcids":["https://orcid.org/0000-0002-8513-239X"]},"institutions":[{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Natalia Alzueta","raw_affiliation_strings":["Hospital Reina Sof\u00eda, Navarre Health Service, 31500 Tudela, Spain","IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain"],"raw_orcid":"https://orcid.org/0000-0002-8513-239X","affiliations":[{"raw_affiliation_string":"Hospital Reina Sof\u00eda, Navarre Health Service, 31500 Tudela, Spain","institution_ids":[]},{"raw_affiliation_string":"IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068874374","display_name":"Amaya Echeverr\u00eda Gorriti","orcid":"https://orcid.org/0000-0001-9225-5323","observed_orcids":["https://orcid.org/0000-0001-9225-5323"]},"institutions":[{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Amaya Echeverr\u00eda","raw_affiliation_strings":["IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","Subdirectorate of Pharmacy, Navarre Health Service, 31002 Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]},{"raw_affiliation_string":"Subdirectorate of Pharmacy, Navarre Health Service, 31002 Pamplona, Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045539141","display_name":"Patricia Garc\u00eda","orcid":"https://orcid.org/0000-0002-5029-9368","observed_orcids":["https://orcid.org/0000-0002-5029-9368"]},"institutions":[{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Patricia Garc\u00eda","raw_affiliation_strings":["IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","Subdirectorate of Pharmacy, Navarre Health Service, 31002 Pamplona, Spain"],"raw_orcid":"https://orcid.org/0000-0002-5029-9368","affiliations":[{"raw_affiliation_string":"IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]},{"raw_affiliation_string":"Subdirectorate of Pharmacy, Navarre Health Service, 31002 Pamplona, Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015849331","display_name":"Lorea Sanz \u00c1lvarez","orcid":"https://orcid.org/0000-0003-0571-5438","observed_orcids":["https://orcid.org/0000-0003-0571-5438"]},"institutions":[{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Lorea Sanz","raw_affiliation_strings":["IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","Subdirectorate of Pharmacy, Navarre Health Service, 31002 Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]},{"raw_affiliation_string":"Subdirectorate of Pharmacy, Navarre Health Service, 31002 Pamplona, Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068708345","display_name":"Alberto Gil-Setas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Alberto Gil-Setas","raw_affiliation_strings":["Clinical Microbiology Department, Hospital Universitario de Navarra, Navarre Health Service, 31008 Pamplona, Spain","IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Microbiology Department, Hospital Universitario de Navarra, Navarre Health Service, 31008 Pamplona, Spain","institution_ids":[]},{"raw_affiliation_string":"IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xabier Beristain","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Xabier Beristain","raw_affiliation_strings":["Clinical Microbiology Department, Hospital Universitario de Navarra, Navarre Health Service, 31008 Pamplona, Spain","IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Microbiology Department, Hospital Universitario de Navarra, Navarre Health Service, 31008 Pamplona, Spain","institution_ids":[]},{"raw_affiliation_string":"IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030785905","display_name":"Pablo Aldaz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088234","display_name":"Servicio Navarro de Salud","ror":"https://ror.org/005dknr06","country_code":"ES","type":"government","lineage":["https://openalex.org/I4210088234"]},{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Pablo Aldaz","raw_affiliation_strings":["IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","San Juan Primary Care Center, Navarre Health Service, 31011 Pamplona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]},{"raw_affiliation_string":"San Juan Primary Care Center, Navarre Health Service, 31011 Pamplona, Spain","institution_ids":["https://openalex.org/I4210088234"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042068297","display_name":"Javier Garj\u00f3n","orcid":"https://orcid.org/0000-0002-0126-7431","observed_orcids":["https://orcid.org/0000-0002-0126-7431"]},"institutions":[{"id":"https://openalex.org/I4210112085","display_name":"Navarre Institute of Health Research","ror":"https://ror.org/023d5h353","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210112085"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Javier Garj\u00f3n","raw_affiliation_strings":["IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","Subdirectorate of Pharmacy, Navarre Health Service, 31002 Pamplona, Spain"],"raw_orcid":"https://orcid.org/0000-0002-0126-7431","affiliations":[{"raw_affiliation_string":"IdiSNA, Health Research Institute of Navarre, 31008 Pamplona, Spain","institution_ids":["https://openalex.org/I4210112085"]},{"raw_affiliation_string":"Subdirectorate of Pharmacy, Navarre Health Service, 31002 Pamplona, Spain","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5008025853"],"corresponding_institution_ids":["https://openalex.org/I4210112085"],"apc_list":{"value":2200,"currency":"CHF","value_usd":2447},"apc_paid":{"value":2200,"currency":"CHF","value_usd":2447},"fwci":2.2809,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.87523408,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"12","issue":"2","first_page":"318","last_page":"318"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11296","display_name":"COVID-19 and healthcare impacts","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10419","display_name":"Pharmaceutical and Antibiotic Environmental Impacts","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9990000128746033},{"id":"https://openalex.org/keywords/antibiotic-use","display_name":"antibiotic use","score":0.9990000128746033},{"id":"https://openalex.org/keywords/medication-use","display_name":"medication use","score":0.7649999856948853},{"id":"https://openalex.org/keywords/defined-daily-doses","display_name":"defined daily doses","score":0.9399999976158142},{"id":"https://openalex.org/keywords/community-antibiotic-use","display_name":"community antibiotic use","score":0.7720000147819519},{"id":"https://openalex.org/keywords/respiratory-tract-infections","display_name":"respiratory infections","score":0.718999981880188},{"id":"https://openalex.org/keywords/amoxicillin","display_name":"amoxicillin","score":0.9089999794960022},{"id":"https://openalex.org/keywords/amoxicillin-clavulanic-acid","display_name":"amoxicillin-clavulanic acid","score":0.9950000047683716},{"id":"https://openalex.org/keywords/levofloxacin","display_name":"levofloxacin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/navarre","display_name":"Navarre","score":0.9580000042915344}],"concepts":[{"id":"https://openalex.org/C89623803","wikidata":"https://www.wikidata.org/wiki/Q12184","display_name":"Pandemic","level":5,"score":0.7307051420211792},{"id":"https://openalex.org/C2779708577","wikidata":"https://www.wikidata.org/wiki/Q201928","display_name":"Amoxicillin","level":3,"score":0.6016250848770142},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.565131425857544},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5345069169998169},{"id":"https://openalex.org/C2909024267","wikidata":"https://www.wikidata.org/wiki/Q39046682","display_name":"Interrupted Time Series Analysis","level":2,"score":0.5126653909683228},{"id":"https://openalex.org/C2779454058","wikidata":"https://www.wikidata.org/wiki/Q415709","display_name":"Clavulanic acid","level":4,"score":0.5067647099494934},{"id":"https://openalex.org/C30772137","wikidata":"https://www.wikidata.org/wiki/Q5164762","display_name":"Consumption (sociology)","level":2,"score":0.5022318363189697},{"id":"https://openalex.org/C2776865356","wikidata":"https://www.wikidata.org/wiki/Q1182681","display_name":"Defined daily dose","level":3,"score":0.4857478737831116},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.4618939161300659},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.4539889097213745},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.326435387134552},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.19695255160331726},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.17886734008789062},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1673021912574768},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.10948354005813599},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09630417823791504},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/antibiotics12020318","doi":"https://doi.org/10.3390/antibiotics12020318","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antibiotics12020318","pdf_url":"https://www.mdpi.com/2079-6382/12/2/318/pdf?version=1675399614","source":{"id":"https://openalex.org/S2736332253","display_name":"Antibiotics","issn_l":"2079-6382","issn":["2079-6382"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antibiotics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9952456","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9952456","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9952456/pdf/antibiotics-12-00318.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antibiotics (Basel)","raw_type":"Text"},{"id":"pmid:36830228","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36830228","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antibiotics (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:63da51cdcc4446629bd3f9777934903e","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/63da51cdcc4446629bd3f9777934903e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Antibiotics, Vol 12, Iss 2, p 318 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/antibiotics12020318","doi":"https://doi.org/10.3390/antibiotics12020318","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antibiotics12020318","pdf_url":"https://www.mdpi.com/2079-6382/12/2/318/pdf?version=1675399614","source":{"id":"https://openalex.org/S2736332253","display_name":"Antibiotics","issn_l":"2079-6382","issn":["2079-6382"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antibiotics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4319081990.pdf","grobid_xml":"https://content.openalex.org/works/W4319081990.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W2009612882","https://openalex.org/W2093259753","https://openalex.org/W2110132657","https://openalex.org/W2763845543","https://openalex.org/W2957488451","https://openalex.org/W3001118548","https://openalex.org/W3010930696","https://openalex.org/W3025928092","https://openalex.org/W3086437033","https://openalex.org/W3092820005","https://openalex.org/W3092989135","https://openalex.org/W3113601412","https://openalex.org/W3127349317","https://openalex.org/W3128204199","https://openalex.org/W3151080094","https://openalex.org/W3214518775","https://openalex.org/W3216351184","https://openalex.org/W4206677002","https://openalex.org/W4210655082","https://openalex.org/W4224309274"],"related_works":["https://openalex.org/W4407719720","https://openalex.org/W4378172909","https://openalex.org/W4386467373","https://openalex.org/W4313413034","https://openalex.org/W4207011026","https://openalex.org/W4399329262","https://openalex.org/W4316038145","https://openalex.org/W4391592494","https://openalex.org/W4302306833","https://openalex.org/W4293560488"],"abstract_inverted_index":{"On":[0],"11":[1],"March":[2],"2020,":[3,80],"the":[4,20,49,54,57,69,73,76,102,113,117,126,180,185],"World":[5],"Health":[6],"Organization":[7],"declared":[8],"coronavirus":[9],"disease":[10],"19":[11],"(COVID-19)":[12],"a":[13],"global":[14,132,181],"pandemic.":[15,128],"This":[16],"exceptional":[17],"situation":[18],"changed":[19],"world":[21,186],"not":[22],"only":[23],"in":[24,32,59,72,119,139,144],"terms":[25,33],"of":[26,34,43,51,98,116,121,131,141,155,173,175],"mortality":[27],"and":[28,36,81,96,124,143,166],"morbidity,":[29],"but":[30],"also":[31,168],"epidemiology":[35],"health":[37],"system":[38],"resources":[39],"consumption.":[40],"The":[41,129,153],"objective":[42],"this":[44],"work":[45,188],"was":[46,66,109,135],"to":[47,111,179,187],"analyze":[48],"consumption":[50,71,122,134],"antibiotics":[52,157,176],"during":[53,75],"period":[55,149],"around":[56],"pandemic":[58,151],"our":[60],"region.":[61],"A":[62],"drug":[63],"utilization":[64],"study":[65],"performed":[67,110],"comparing":[68],"antibiotic":[70,84,133],"community":[74],"years":[77],"2018,":[78],"2019,":[79],"2021.":[82],"Quarterly":[83],"use":[85,154,174],"(defined":[86],"daily":[87],"doses":[88],"(DDD)":[89],"per":[90,93],"1000":[91],"inhabitants":[92],"day":[94],"(DID))":[95],"number":[97,140],"patients":[99,142],"treated":[100],"were":[101],"outcomes.":[103],"Interrupted":[104],"time":[105],"series":[106],"regression":[107],"analysis":[108],"estimate":[112],"statistical":[114],"significance":[115],"change":[118],"level":[120],"before":[123],"after":[125],"COVID-19":[127],"drop":[130],"statistically":[136],"significant,":[137],"both":[138],"DID":[145],"when":[146],"analyzing":[147],"pre-pandemic":[148],"versus":[150],"period.":[152],"strategic":[156],"for":[158],"respiratory":[159],"infections":[160],"such":[161],"as":[162],"amoxicillin,":[163],"amoxicillin-clavulanic":[164],"acid,":[165],"levofloxacin":[167],"decreased":[169],"significantly.":[170],"Seasonal":[171],"pattern":[172],"disappeared":[177],"due":[178],"measures":[182],"imposed":[183],"over":[184],"against":[189],"COVID-19.":[190]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2023-02-04T00:00:00"}