{"id":"https://openalex.org/W4318926327","doi":"https://doi.org/10.1007/s11011-023-01165-y","title":"An overview of hyperbaric oxygen preconditioning against ischemic stroke","display_name":"An overview of hyperbaric oxygen preconditioning against ischemic stroke","publication_year":2023,"publication_date":"2023-02-02","ids":{"openalex":"https://openalex.org/W4318926327","doi":"https://doi.org/10.1007/s11011-023-01165-y","pmid":"https://pubmed.ncbi.nlm.nih.gov/36729260","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10106353"},"language":"en","primary_location":{"id":"doi:10.1007/s11011-023-01165-y","doi":"https://doi.org/10.1007/s11011-023-01165-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11011-023-01165-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11011-023-01165-y.pdf","source":{"id":"https://openalex.org/S31409034","display_name":"Metabolic Brain Disease","issn_l":"0885-7490","issn":["0885-7490","1573-7365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolic Brain Disease","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s11011-023-01165-y.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010087073","display_name":"Xuyi Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuyi Wu","raw_affiliation_strings":["Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China","Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China","West China School of Nursing, Sichuan University, Chengdu, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"West China School of Nursing, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057537365","display_name":"Jiuhong You","orcid":"https://orcid.org/0000-0002-1310-9203","observed_orcids":["https://orcid.org/0000-0002-1310-9203"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiuhong You","raw_affiliation_strings":["Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China","Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China","School of Rehabilitation Sciences, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"School of Rehabilitation Sciences, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100354374","display_name":"Xinxin Chen","orcid":"https://orcid.org/0000-0003-3929-2314","observed_orcids":["https://orcid.org/0000-0003-3929-2314"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinxin Chen","raw_affiliation_strings":["Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China","Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China","School of Rehabilitation Sciences, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"School of Rehabilitation Sciences, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023574067","display_name":"Mei Zhou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mei Zhou","raw_affiliation_strings":["Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China","Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China","School of Rehabilitation Sciences, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"School of Rehabilitation Sciences, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100777179","display_name":"Hui Ma","orcid":"https://orcid.org/0000-0002-0995-2345","observed_orcids":["https://orcid.org/0000-0002-0995-2345"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Ma","raw_affiliation_strings":["Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China","Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China","School of Rehabilitation Sciences, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"School of Rehabilitation Sciences, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tianle Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tianle Zhang","raw_affiliation_strings":["Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064988364","display_name":"Cheng Huang","orcid":"https://orcid.org/0000-0003-3427-5937","observed_orcids":["https://orcid.org/0000-0003-3427-5937"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Cheng Huang","raw_affiliation_strings":["Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China. chenghuang_scu@163.com","Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China. chenghuang_scu@163.com","Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China"],"raw_orcid":"https://orcid.org/0000-0003-3427-5937","affiliations":[{"raw_affiliation_string":"Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China. chenghuang_scu@163.com","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China. chenghuang_scu@163.com","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5064988364"],"corresponding_institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":{"value":4190,"currency":"USD","value_usd":4190},"fwci":0.8554,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.69375,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"38","issue":"3","first_page":"855","last_page":"872"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.7734000086784363,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.7734000086784363,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13796","display_name":"Neurological Disorders and Treatments","score":0.05299999937415123,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.037300001829862595,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperbaric-oxygen-therapy","display_name":"hyperbaric oxygen therapy","score":0.8539999723434448},{"id":"https://openalex.org/keywords/preconditioning","display_name":"preconditioning","score":0.7870000004768372},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.9909999966621399},{"id":"https://openalex.org/keywords/stroke-prevention","display_name":"stroke prevention","score":0.8550000190734863},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.6439999938011169},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.8289999961853027},{"id":"https://openalex.org/keywords/apoptosis-inhibition","display_name":"apoptosis inhibition","score":0.9129999876022339},{"id":"https://openalex.org/keywords/autophagy","display_name":"autophagy","score":1.0},{"id":"https://openalex.org/keywords/heat-shock-proteins","display_name":"heat shock proteins","score":0.8669999837875366},{"id":"https://openalex.org/keywords/hypoxia-inducible-factor-1","display_name":"HIF-1","score":0.9919999837875366},{"id":"https://openalex.org/keywords/erythropoietin","display_name":"erythropoietin","score":1.0},{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.9869999885559082},{"id":"https://openalex.org/keywords/stem-cell-therapy","display_name":"stem cell therapy","score":0.9369999766349792}],"concepts":[{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.7829961180686951},{"id":"https://openalex.org/C2994405533","wikidata":"https://www.wikidata.org/wiki/Q731615","display_name":"Hyperbaric oxygen","level":2,"score":0.7708214521408081},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.5729351043701172},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5585485100746155},{"id":"https://openalex.org/C3020199598","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischemic stroke","level":3,"score":0.45381492376327515},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4278857409954071},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.2929258346557617},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.2570239305496216},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.11251652240753174},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08393946290016174},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000083242","descriptor_name":"Ischemic Stroke","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006931","descriptor_name":"Hyperbaric Oxygenation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s11011-023-01165-y","doi":"https://doi.org/10.1007/s11011-023-01165-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11011-023-01165-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11011-023-01165-y.pdf","source":{"id":"https://openalex.org/S31409034","display_name":"Metabolic Brain Disease","issn_l":"0885-7490","issn":["0885-7490","1573-7365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolic Brain Disease","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10106353","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10106353","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10106353/pdf/11011_2023_Article_1165.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metab Brain Dis","raw_type":"Text"},{"id":"pmid:36729260","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36729260","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolic brain disease","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1007/s11011-023-01165-y","doi":"https://doi.org/10.1007/s11011-023-01165-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11011-023-01165-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11011-023-01165-y.pdf","source":{"id":"https://openalex.org/S31409034","display_name":"Metabolic Brain Disease","issn_l":"0885-7490","issn":["0885-7490","1573-7365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolic Brain Disease","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5630652301","display_name":null,"funder_award_id":"2021HXFH063","funder_id":"https://openalex.org/F4320336042","funder_display_name":"West China Hospital, Sichuan University"}],"funders":[{"id":"https://openalex.org/F4320336042","display_name":"West China Hospital, Sichuan University","ror":"https://ror.org/007mrxy13"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4318926327.pdf","grobid_xml":"https://content.openalex.org/works/W4318926327.grobid-xml"},"referenced_works_count":210,"referenced_works":["https://openalex.org/W100209204","https://openalex.org/W128151115","https://openalex.org/W148052990","https://openalex.org/W152049102","https://openalex.org/W237336271","https://openalex.org/W1214988809","https://openalex.org/W1495983806","https://openalex.org/W1503505289","https://openalex.org/W1512037315","https://openalex.org/W1523693806","https://openalex.org/W1535385532","https://openalex.org/W1557087064","https://openalex.org/W1677040403","https://openalex.org/W1725345624","https://openalex.org/W1796054280","https://openalex.org/W1814262012","https://openalex.org/W1879151950","https://openalex.org/W1896626713","https://openalex.org/W1925799544","https://openalex.org/W1937401270","https://openalex.org/W1955736456","https://openalex.org/W1965546263","https://openalex.org/W1965707265","https://openalex.org/W1966752305","https://openalex.org/W1968310727","https://openalex.org/W1970820483","https://openalex.org/W1971391716","https://openalex.org/W1971403257","https://openalex.org/W1972432707","https://openalex.org/W1973063537","https://openalex.org/W1974114868","https://openalex.org/W1974739417","https://openalex.org/W1976869427","https://openalex.org/W1978726693","https://openalex.org/W1979717090","https://openalex.org/W1980347983","https://openalex.org/W1986790448","https://openalex.org/W1987278634","https://openalex.org/W1988591558","https://openalex.org/W1988970703","https://openalex.org/W1991660337","https://openalex.org/W1993213847","https://openalex.org/W1996574563","https://openalex.org/W1997838747","https://openalex.org/W1999199122","https://openalex.org/W1999335215","https://openalex.org/W2000824777","https://openalex.org/W2001437300","https://openalex.org/W2003676659","https://openalex.org/W2005674716","https://openalex.org/W2006685212","https://openalex.org/W2009914008","https://openalex.org/W2011810742","https://openalex.org/W2012974829","https://openalex.org/W2013351805","https://openalex.org/W2015541518","https://openalex.org/W2016597337","https://openalex.org/W2016934775","https://openalex.org/W2017117197","https://openalex.org/W2018488451","https://openalex.org/W2018725062","https://openalex.org/W2019106516","https://openalex.org/W2020279953","https://openalex.org/W2021435547","https://openalex.org/W2023250693","https://openalex.org/W2025131475","https://openalex.org/W2028775513","https://openalex.org/W2029011122","https://openalex.org/W2029068688","https://openalex.org/W2029213094","https://openalex.org/W2029276286","https://openalex.org/W2031492796","https://openalex.org/W2031603326","https://openalex.org/W2033910705","https://openalex.org/W2035572403","https://openalex.org/W2035936685","https://openalex.org/W2039001246","https://openalex.org/W2040585598","https://openalex.org/W2041098348","https://openalex.org/W2041204304","https://openalex.org/W2041646382","https://openalex.org/W2042216712","https://openalex.org/W2042271730","https://openalex.org/W2043214240","https://openalex.org/W2047229538","https://openalex.org/W2048130120","https://openalex.org/W2048277283","https://openalex.org/W2049528479","https://openalex.org/W2050320551","https://openalex.org/W2054596356","https://openalex.org/W2055504048","https://openalex.org/W2055801667","https://openalex.org/W2057785271","https://openalex.org/W2058291863","https://openalex.org/W2058494321","https://openalex.org/W2060844162","https://openalex.org/W2066200472","https://openalex.org/W2066310239","https://openalex.org/W2066432360","https://openalex.org/W2067358204","https://openalex.org/W2067667174","https://openalex.org/W2069201318","https://openalex.org/W2071355142","https://openalex.org/W2072035011","https://openalex.org/W2072634616","https://openalex.org/W2073292880","https://openalex.org/W2073427034","https://openalex.org/W2076034559","https://openalex.org/W2076415895","https://openalex.org/W2078490782","https://openalex.org/W2082221119","https://openalex.org/W2084940422","https://openalex.org/W2085609942","https://openalex.org/W2085925390","https://openalex.org/W2086109976","https://openalex.org/W2089172549","https://openalex.org/W2090321764","https://openalex.org/W2093352910","https://openalex.org/W2094164804","https://openalex.org/W2096592089","https://openalex.org/W2097510913","https://openalex.org/W2098615761","https://openalex.org/W2100978260","https://openalex.org/W2101736298","https://openalex.org/W2101957440","https://openalex.org/W2102726882","https://openalex.org/W2103108890","https://openalex.org/W2104246038","https://openalex.org/W2106949373","https://openalex.org/W2108893308","https://openalex.org/W2109759840","https://openalex.org/W2111994809","https://openalex.org/W2113999599","https://openalex.org/W2114445825","https://openalex.org/W2114806766","https://openalex.org/W2120574979","https://openalex.org/W2121212243","https://openalex.org/W2121343458","https://openalex.org/W2123927456","https://openalex.org/W2127898315","https://openalex.org/W2128122339","https://openalex.org/W2141852514","https://openalex.org/W2142066097","https://openalex.org/W2143029198","https://openalex.org/W2145519598","https://openalex.org/W2146217294","https://openalex.org/W2150494811","https://openalex.org/W2151283331","https://openalex.org/W2153376781","https://openalex.org/W2156827221","https://openalex.org/W2157045574","https://openalex.org/W2158929015","https://openalex.org/W2159627505","https://openalex.org/W2160394092","https://openalex.org/W2160708843","https://openalex.org/W2161363180","https://openalex.org/W2162264368","https://openalex.org/W2163161503","https://openalex.org/W2165201727","https://openalex.org/W2165623186","https://openalex.org/W2170900458","https://openalex.org/W2214380859","https://openalex.org/W2229999843","https://openalex.org/W2322458195","https://openalex.org/W2328103190","https://openalex.org/W2331339331","https://openalex.org/W2331794026","https://openalex.org/W2333791479","https://openalex.org/W2337769418","https://openalex.org/W2342940718","https://openalex.org/W2357938875","https://openalex.org/W2395089787","https://openalex.org/W2396498623","https://openalex.org/W2410369341","https://openalex.org/W2410915244","https://openalex.org/W2441580746","https://openalex.org/W2521259710","https://openalex.org/W2536636502","https://openalex.org/W2563973506","https://openalex.org/W2750305070","https://openalex.org/W2759984178","https://openalex.org/W2762859933","https://openalex.org/W2773986492","https://openalex.org/W2803306216","https://openalex.org/W2803377995","https://openalex.org/W2805124740","https://openalex.org/W2883054877","https://openalex.org/W2893207047","https://openalex.org/W2900850545","https://openalex.org/W2901097231","https://openalex.org/W2902311424","https://openalex.org/W2937907904","https://openalex.org/W2967289403","https://openalex.org/W2986841791","https://openalex.org/W2991492226","https://openalex.org/W3002743042","https://openalex.org/W3003281637","https://openalex.org/W3008624617","https://openalex.org/W3119945662","https://openalex.org/W3120959248","https://openalex.org/W3122889888","https://openalex.org/W3127428086","https://openalex.org/W3175453591","https://openalex.org/W3194056978","https://openalex.org/W3199969939","https://openalex.org/W4210663099","https://openalex.org/W4283017392","https://openalex.org/W4283221161","https://openalex.org/W4283392547","https://openalex.org/W4289541659"],"related_works":["https://openalex.org/W3083080816","https://openalex.org/W2565186884","https://openalex.org/W2991492226","https://openalex.org/W3122889888","https://openalex.org/W2111432684","https://openalex.org/W116309773","https://openalex.org/W2092761039","https://openalex.org/W2125367061","https://openalex.org/W2405044203","https://openalex.org/W2980013775"],"abstract_inverted_index":{"Ischemic":[0],"stroke":[1,181],"(IS)":[2],"has":[3],"become":[4],"the":[5,15,50,56,98,122,135,148,161],"second":[6],"leading":[7],"cause":[8],"of":[9,17,52,59,68,124,137],"morbidity":[10],"and":[11,14,54,77,82,91,93,109,158],"mortality":[12],"worldwide,":[13],"prevention":[16],"IS":[18,53,71,114,127],"should":[19,173],"be":[20,34,105,155,165],"given":[21],"high":[22],"priority.":[23],"Recent":[24],"studies":[25],"have":[26,128],"indicated":[27],"that":[28],"hyperbaric":[29],"oxygen":[30],"preconditioning":[31,177],"(HBO-PC)":[32],"may":[33,72,104],"a":[35,107,166],"protective":[36,95],"nonpharmacological":[37],"method,":[38],"but":[39],"its":[40],"underlying":[41,57],"mechanisms":[42],"remain":[43],"poorly":[44],"defined.":[45],"This":[46],"study":[47],"comprehensively":[48],"reviewed":[49],"pathophysiology":[51],"revealed":[55],"mechanism":[58],"HBO-PC":[60,69,103,125],"in":[61,115,132],"protection":[62],"against":[63,70],"IS.":[64],"The":[65],"preventive":[66],"effects":[67,96],"include":[73],"inducing":[74],"antioxidant,":[75],"anti-inflammation,":[76],"anti-apoptosis":[78],"capacity;":[79],"activating":[80],"autophagy":[81],"immune":[83],"responses;":[84],"upregulating":[85],"heat":[86],"shock":[87],"proteins,":[88],"hypoxia-inducible":[89],"factor-1,":[90],"erythropoietin;":[92],"exerting":[94],"upon":[97],"blood-brain":[99],"barrier.":[100],"In":[101,169],"addition,":[102,170],"considered":[106],"safe":[108],"effective":[110],"method":[111],"to":[112,144,150,154,179],"prevent":[113],"combination":[116],"with":[117],"stem":[118],"cell":[119],"therapy.":[120],"Although":[121],"benefits":[123],"on":[126],"been":[129],"widely":[130],"observed":[131],"recent":[133],"research,":[134],"implementation":[136],"this":[138],"technique":[139],"is":[140],"still":[141],"controversial":[142],"due":[143],"regimen":[145,163,178],"differences.":[146],"Transferring":[147],"results":[149],"clinical":[151],"application":[152],"needs":[153,183],"taken":[156],"carefully,":[157],"screening":[159],"for":[160],"optimal":[162],"would":[164],"daunting":[167],"task.":[168],"whether":[171],"we":[172],"prescribe":[174],"an":[175],"individualized":[176],"each":[180],"patient":[182],"further":[184],"exploration.":[185]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-02-03T00:00:00"}
