{"id":"https://openalex.org/W4318617822","doi":"https://doi.org/10.1007/978-981-19-3824-5_27","title":"Role of Telomere and Telomerase Activator in Ageing and Cancer","display_name":"Role of Telomere and Telomerase Activator in Ageing and Cancer","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4318617822","doi":"https://doi.org/10.1007/978-981-19-3824-5_27"},"language":"en","primary_location":{"id":"doi:10.1007/978-981-19-3824-5_27","doi":"https://doi.org/10.1007/978-981-19-3824-5_27","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-981-19-3824-5_27","pdf_url":null,"source":{"id":"https://openalex.org/S4363606810","display_name":"Handbook of Animal Models and its Uses in Cancer Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Animal Models and its Uses in Cancer Research","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4318617650","display_name":"Handbook of Animal Models and its Uses in Cancer Research"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012063751","display_name":"Dikshita Deka","orcid":"https://orcid.org/0000-0001-5087-9023","observed_orcids":["https://orcid.org/0000-0001-5087-9023"]},"institutions":[{"id":"https://openalex.org/I220840466","display_name":"Chettinad Academy of Research and Education","ror":"https://ror.org/0394w2w14","country_code":"IN","type":"education","lineage":["https://openalex.org/I220840466"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Dikshita Deka","raw_affiliation_strings":["Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai, India","institution_ids":["https://openalex.org/I220840466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012932797","display_name":"N. R. Shruthi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I220840466","display_name":"Chettinad Academy of Research and Education","ror":"https://ror.org/0394w2w14","country_code":"IN","type":"education","lineage":["https://openalex.org/I220840466"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Shruthi N. R.","raw_affiliation_strings":["Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai, India","institution_ids":["https://openalex.org/I220840466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031399876","display_name":"Surajit Pathak","orcid":"https://orcid.org/0000-0002-7306-1272","observed_orcids":["https://orcid.org/0000-0002-7306-1272"]},"institutions":[{"id":"https://openalex.org/I220840466","display_name":"Chettinad Academy of Research and Education","ror":"https://ror.org/0394w2w14","country_code":"IN","type":"education","lineage":["https://openalex.org/I220840466"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Surajit Pathak","raw_affiliation_strings":["Cancer Biology and Biotechnology Lab, Faculty of Allied Health Sciences, Chettinad Hospital & Research Institute (CHRI), Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai, India","Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Biology and Biotechnology Lab, Faculty of Allied Health Sciences, Chettinad Hospital & Research Institute (CHRI), Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai, India","institution_ids":["https://openalex.org/I220840466"]},{"raw_affiliation_string":"Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai, India","institution_ids":["https://openalex.org/I220840466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053228435","display_name":"B. Priyadarshini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I220840466","display_name":"Chettinad Academy of Research and Education","ror":"https://ror.org/0394w2w14","country_code":"IN","type":"education","lineage":["https://openalex.org/I220840466"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"B. Priyadarshini","raw_affiliation_strings":["Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai, India","institution_ids":["https://openalex.org/I220840466"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024625640","display_name":"Antara Banerjee","orcid":"https://orcid.org/0000-0002-5519-6878","observed_orcids":["https://orcid.org/0000-0002-5519-6878"]},"institutions":[{"id":"https://openalex.org/I220840466","display_name":"Chettinad Academy of Research and Education","ror":"https://ror.org/0394w2w14","country_code":"IN","type":"education","lineage":["https://openalex.org/I220840466"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Antara Banerjee","raw_affiliation_strings":["Cancer Biology and Biotechnology Lab, Faculty of Allied Health Sciences, Chettinad Hospital & Research Institute (CHRI), Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai, India","Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Biology and Biotechnology Lab, Faculty of Allied Health Sciences, Chettinad Hospital & Research Institute (CHRI), Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai, India","institution_ids":["https://openalex.org/I220840466"]},{"raw_affiliation_string":"Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai, India","institution_ids":["https://openalex.org/I220840466"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I220840466"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0567867,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"565","last_page":"590"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10937","display_name":"Telomeres, Telomerase, and Senescence","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10937","display_name":"Telomeres, Telomerase, and Senescence","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14135","display_name":"Cancer and biochemical research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/telomeres","display_name":"telomeres","score":0.9229999780654907},{"id":"https://openalex.org/keywords/telomerase","display_name":"telomerase","score":0.9079999923706055},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.765999972820282},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.7459999918937683},{"id":"https://openalex.org/keywords/cellular-senescence","display_name":"cellular senescence","score":0.9710000157356262},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8130000233650208},{"id":"https://openalex.org/keywords/free-radicals","display_name":"free radicals","score":0.7820000052452087},{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.8370000123977661},{"id":"https://openalex.org/keywords/age-related-diseases","display_name":"age-related diseases","score":0.8399999737739563},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7990000247955322},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.7049999833106995}],"concepts":[{"id":"https://openalex.org/C94581717","wikidata":"https://www.wikidata.org/wiki/Q331839","display_name":"Telomerase","level":3,"score":0.956581711769104},{"id":"https://openalex.org/C177336024","wikidata":"https://www.wikidata.org/wiki/Q14872779","display_name":"Telomere","level":3,"score":0.9347207546234131},{"id":"https://openalex.org/C522857546","wikidata":"https://www.wikidata.org/wiki/Q2070979","display_name":"Senescence","level":2,"score":0.6994691491127014},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.46239933371543884},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.4477784037590027},{"id":"https://openalex.org/C500499127","wikidata":"https://www.wikidata.org/wiki/Q332154","display_name":"Ageing","level":2,"score":0.4432090222835541},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44185057282447815},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4103524088859558},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.38044825196266174},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.35561010241508484},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.34134364128112793},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.33983340859413147},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2447347640991211},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18150347471237183},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11151140928268433}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-981-19-3824-5_27","doi":"https://doi.org/10.1007/978-981-19-3824-5_27","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-981-19-3824-5_27","pdf_url":null,"source":{"id":"https://openalex.org/S4363606810","display_name":"Handbook of Animal Models and its Uses in Cancer Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Animal Models and its Uses in Cancer Research","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":84,"referenced_works":["https://openalex.org/W182160512","https://openalex.org/W1808474347","https://openalex.org/W1965684670","https://openalex.org/W1973050694","https://openalex.org/W1976882367","https://openalex.org/W1977172248","https://openalex.org/W1979715837","https://openalex.org/W1980878904","https://openalex.org/W1982395176","https://openalex.org/W1982767015","https://openalex.org/W1983673827","https://openalex.org/W1990185667","https://openalex.org/W1991425040","https://openalex.org/W1992520556","https://openalex.org/W1993091967","https://openalex.org/W1994873752","https://openalex.org/W1997435510","https://openalex.org/W2005996436","https://openalex.org/W2007185373","https://openalex.org/W2009357228","https://openalex.org/W2009478289","https://openalex.org/W2012418095","https://openalex.org/W2015958589","https://openalex.org/W2016517460","https://openalex.org/W2017426888","https://openalex.org/W2022507419","https://openalex.org/W2032685308","https://openalex.org/W2032867856","https://openalex.org/W2037146644","https://openalex.org/W2044758458","https://openalex.org/W2046466087","https://openalex.org/W2046838134","https://openalex.org/W2046989794","https://openalex.org/W2048266866","https://openalex.org/W2049151391","https://openalex.org/W2053796870","https://openalex.org/W2056446114","https://openalex.org/W2057483675","https://openalex.org/W2058778703","https://openalex.org/W2061619522","https://openalex.org/W2061971307","https://openalex.org/W2062085206","https://openalex.org/W2077608775","https://openalex.org/W2087513367","https://openalex.org/W2088672106","https://openalex.org/W2089529341","https://openalex.org/W2095696971","https://openalex.org/W2097529540","https://openalex.org/W2099553428","https://openalex.org/W2102172732","https://openalex.org/W2106268089","https://openalex.org/W2107476202","https://openalex.org/W2107638414","https://openalex.org/W2108887402","https://openalex.org/W2109460321","https://openalex.org/W2110419228","https://openalex.org/W2110727184","https://openalex.org/W2126787895","https://openalex.org/W2127657628","https://openalex.org/W2131646714","https://openalex.org/W2132606465","https://openalex.org/W2136856258","https://openalex.org/W2140400644","https://openalex.org/W2142075099","https://openalex.org/W2145859123","https://openalex.org/W2148140378","https://openalex.org/W2150490516","https://openalex.org/W2150748567","https://openalex.org/W2153312037","https://openalex.org/W2161257922","https://openalex.org/W2168783201","https://openalex.org/W2273121121","https://openalex.org/W2284244281","https://openalex.org/W2321647501","https://openalex.org/W2599022942","https://openalex.org/W2754871120","https://openalex.org/W2796882889","https://openalex.org/W2799986334","https://openalex.org/W2824408623","https://openalex.org/W2883101927","https://openalex.org/W2969670569","https://openalex.org/W2970657071","https://openalex.org/W2971224745","https://openalex.org/W3081649655"],"related_works":["https://openalex.org/W2126932273","https://openalex.org/W2046498189","https://openalex.org/W1981966951","https://openalex.org/W2054165069","https://openalex.org/W1995726348","https://openalex.org/W2027837748","https://openalex.org/W2898656280","https://openalex.org/W1996384141","https://openalex.org/W1986506996","https://openalex.org/W2058669007"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-01-31T00:00:00"}