{"id":"https://openalex.org/W4317543115","doi":"https://doi.org/10.1093/ndt/gfad017","title":"Suppression of thyroid profile during roxadustat treatment in chronic kidney disease patients","display_name":"Suppression of thyroid profile during roxadustat treatment in chronic kidney disease patients","publication_year":2023,"publication_date":"2023-01-20","ids":{"openalex":"https://openalex.org/W4317543115","doi":"https://doi.org/10.1093/ndt/gfad017","pmid":"https://pubmed.ncbi.nlm.nih.gov/36662034"},"language":"en","primary_location":{"id":"doi:10.1093/ndt/gfad017","doi":"https://doi.org/10.1093/ndt/gfad017","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ndt/gfad017","pdf_url":"https://academic.oup.com/ndt/advance-article-pdf/doi/10.1093/ndt/gfad017/49880969/gfad017.pdf","source":{"id":"https://openalex.org/S186113128","display_name":"Nephrology Dialysis Transplantation","issn_l":"0931-0509","issn":["0931-0509","1460-2385"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrology Dialysis Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/ndt/advance-article-pdf/doi/10.1093/ndt/gfad017/49880969/gfad017.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062101836","display_name":"Yuan Cheng","orcid":"https://orcid.org/0000-0003-2677-0698","observed_orcids":["https://orcid.org/0000-0003-2677-0698"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan Cheng","raw_affiliation_strings":["Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China"],"raw_orcid":"https://orcid.org/0000-0003-2677-0698","affiliations":[{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Qiong Xiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210120522","display_name":"Shantou University Medical College","ror":"https://ror.org/02gxych78","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210120522"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiong Xiang","raw_affiliation_strings":["Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","Shantou University Medical College , Shantou, Guangdong ,","Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","Shantou University Medical College , Shantou, Guangdong , P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Shantou University Medical College , Shantou, Guangdong ,","institution_ids":["https://openalex.org/I4210120522"]},{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Shantou University Medical College , Shantou, Guangdong , P.R. China","institution_ids":["https://openalex.org/I4210120522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101764911","display_name":"Tao Cao","orcid":"https://orcid.org/0000-0001-8713-8800","observed_orcids":["https://orcid.org/0000-0001-8713-8800"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tao Cao","raw_affiliation_strings":["Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047051172","display_name":"Fei Tang","orcid":"https://orcid.org/0000-0003-2521-4825","observed_orcids":["https://orcid.org/0000-0003-2521-4825"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fei Tang","raw_affiliation_strings":["Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100416037","display_name":"Jia Chen","orcid":"https://orcid.org/0000-0003-4217-5039","observed_orcids":["https://orcid.org/0000-0003-4217-5039"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia Chen","raw_affiliation_strings":["Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dongli Qi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dongli Qi","raw_affiliation_strings":["Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036202917","display_name":"Haofei Hu","orcid":"https://orcid.org/0000-0001-6061-6796","observed_orcids":["https://orcid.org/0000-0001-6061-6796"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haofei Hu","raw_affiliation_strings":["Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102939826","display_name":"Haiying Song","orcid":"https://orcid.org/0000-0003-4086-6194","observed_orcids":["https://orcid.org/0000-0003-4086-6194"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haiying Song","raw_affiliation_strings":["Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050271098","display_name":"Zheyi Chang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zheyi Chang","raw_affiliation_strings":["Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104110611","display_name":"Ming Ku","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ming Ku","raw_affiliation_strings":["Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004583134","display_name":"Xinglin Chen","orcid":"https://orcid.org/0009-0004-2272-1439","observed_orcids":["https://orcid.org/0009-0004-2272-1439","https://orcid.org/0000-0002-5820-9224"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xinglin Chen","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Empower U, X&Y Solutions Inc. , Boston, MA ,","Department of Epidemiology and Biostatistics, Empower U, X&Y Solutions Inc. , Boston, MA , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Empower U, X&Y Solutions Inc. , Boston, MA ,","institution_ids":[]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Empower U, X&Y Solutions Inc. , Boston, MA , USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100435627","display_name":"Chi Chen","orcid":"https://orcid.org/0000-0003-3291-0319","observed_orcids":["https://orcid.org/0000-0003-3291-0319"]},"institutions":[{"id":"https://openalex.org/I110640572","display_name":"Guiyang College of Traditional Chinese Medicine","ror":"https://ror.org/02bb8n686","country_code":"CN","type":"education","lineage":["https://openalex.org/I110640572"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chi Chen","raw_affiliation_strings":["Department of Immunology and Microbiology, Guiyang College of Traditional Chinese Medicine , Guiyang, Guizhou ,","Department of Immunology and Microbiology, Guiyang College of Traditional Chinese Medicine , Guiyang, Guizhou , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology and Microbiology, Guiyang College of Traditional Chinese Medicine , Guiyang, Guizhou ,","institution_ids":["https://openalex.org/I110640572"]},{"raw_affiliation_string":"Department of Immunology and Microbiology, Guiyang College of Traditional Chinese Medicine , Guiyang, Guizhou , China","institution_ids":["https://openalex.org/I110640572"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057620126","display_name":"Qijun Wan","orcid":"https://orcid.org/0000-0002-5039-4015","observed_orcids":["https://orcid.org/0000-0002-5039-4015","https://orcid.org/0000-0002-1304-1333","https://orcid.org/0009-0000-8822-2844"]},"institutions":[{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210164332","display_name":"Shenzhen Second People's Hospital","ror":"https://ror.org/05c74bq69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164332"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qijun Wan","raw_affiliation_strings":["Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong ,","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]},{"raw_affiliation_string":"Department of Nephrology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University , Shenzhen, Guangdong , P.R. China","institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5057620126"],"corresponding_institution_ids":["https://openalex.org/I180726961","https://openalex.org/I4210164332"],"apc_list":{"value":3182,"currency":"EUR","value_usd":3442},"apc_paid":null,"fwci":3.5958,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.93329982,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"38","issue":"6","first_page":"1567","last_page":"1570"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.014700000174343586,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/roxadustat","display_name":"roxadustat","score":1.0},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.8730000257492065},{"id":"https://openalex.org/keywords/anemia-of-chronic-kidney-disease","display_name":"anemia of chronic kidney disease","score":0.8560000061988831},{"id":"https://openalex.org/keywords/thyroid-stimulating-hormone","display_name":"thyroid-stimulating hormone","score":0.8790000081062317},{"id":"https://openalex.org/keywords/thyroid-function","display_name":"thyroid function","score":0.7139999866485596},{"id":"https://openalex.org/keywords/prolyl-hydroxylase-inhibitors","display_name":"prolyl hydroxylase inhibitors","score":0.8820000290870667},{"id":"https://openalex.org/keywords/erythropoietin","display_name":"erythropoietin","score":0.9300000071525574},{"id":"https://openalex.org/keywords/hypothyroidism","display_name":"hypothyroidism","score":0.8489999771118164},{"id":"https://openalex.org/keywords/hemodialysis","display_name":"hemodialysis","score":0.8539999723434448},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.6140000224113464}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9645862579345703},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.7345972657203674},{"id":"https://openalex.org/C2778534260","wikidata":"https://www.wikidata.org/wiki/Q218706","display_name":"Erythropoietin","level":2,"score":0.6722825169563293},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6234418153762817},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.5601774454116821},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.5152897834777832},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4740709364414215},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.45086178183555603},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.44465991854667664},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.42260679602622986},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4167792797088623},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4128720164299011}],"mesh":[{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007546","descriptor_name":"Isoquinolines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007546","descriptor_name":"Isoquinolines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007546","descriptor_name":"Isoquinolines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/ndt/gfad017","doi":"https://doi.org/10.1093/ndt/gfad017","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ndt/gfad017","pdf_url":"https://academic.oup.com/ndt/advance-article-pdf/doi/10.1093/ndt/gfad017/49880969/gfad017.pdf","source":{"id":"https://openalex.org/S186113128","display_name":"Nephrology Dialysis Transplantation","issn_l":"0931-0509","issn":["0931-0509","1460-2385"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrology Dialysis Transplantation","raw_type":"journal-article"},{"id":"pmid:36662034","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36662034","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/ndt/gfad017","doi":"https://doi.org/10.1093/ndt/gfad017","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ndt/gfad017","pdf_url":"https://academic.oup.com/ndt/advance-article-pdf/doi/10.1093/ndt/gfad017/49880969/gfad017.pdf","source":{"id":"https://openalex.org/S186113128","display_name":"Nephrology Dialysis Transplantation","issn_l":"0931-0509","issn":["0931-0509","1460-2385"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrology Dialysis Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8799999952316284}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4317543115.pdf","grobid_xml":"https://content.openalex.org/works/W4317543115.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W65817400","https://openalex.org/W1549306000","https://openalex.org/W2042960850","https://openalex.org/W2047382827","https://openalex.org/W2124116160","https://openalex.org/W2137248735","https://openalex.org/W2162704042","https://openalex.org/W2593244426","https://openalex.org/W2891009351","https://openalex.org/W2963534431","https://openalex.org/W2964045421","https://openalex.org/W2978490545","https://openalex.org/W3124445434","https://openalex.org/W3139478566","https://openalex.org/W3183833271","https://openalex.org/W4205283399","https://openalex.org/W4224023905"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W1588725841","https://openalex.org/W2179797810","https://openalex.org/W4256664370","https://openalex.org/W2415995798","https://openalex.org/W1592859225","https://openalex.org/W1602405375","https://openalex.org/W2033945997","https://openalex.org/W2085281796","https://openalex.org/W2333298519"],"abstract_inverted_index":{"Renal":[0],"anaemia":[1,15,58],"is":[2,25,40,51,138],"a":[3,41,121],"common":[4,65],"complication":[5],"of":[6,14,20,35,57,89,92,101,124,134,153],"chronic":[7],"kidney":[8],"disease":[9,37,126],"(CKD)":[10],"and":[11,33,81,127,161],"the":[12,18,55,135,151],"severity":[13],"increases":[16],"with":[17,30,99,115],"deterioration":[19],"renal":[21],"function":[22],"[1].":[23],"Anaemia":[24],"known":[26],"to":[27,120,149],"be":[28],"associated":[29],"increased":[31],"morbidity":[32],"mortality":[34,129],"cardiovascular":[36,125],"[2].":[38],"Roxadustat":[39],"new":[42],"oral":[43],"prolyl":[44],"hydroxylase":[45],"domain":[46],"(PHD)":[47],"protein":[48],"inhibitor":[49],"that":[50],"extensively":[52],"used":[53],"for":[54],"treatment":[56,142],"in":[59,69,95,113,165],"CKD":[60,116,166],"patients":[61,98,114,167],"[3\u20137].":[62],"The":[63],"most":[64],"side":[66],"effects":[67,152],"reported":[68],"clinical":[70],"trials":[71],"are":[72],"high":[73],"blood":[74],"pressure,":[75],"myocardial":[76],"infarction,":[77],"heart":[78],"failure,":[79],"infections":[80],"thrombosis.":[82],"So":[83],"far,":[84],"only":[85],"two":[86],"case":[87],"reports":[88],"Roxadustat-induced":[90],"suppression":[91,133],"thyrotropin":[93],"secretion":[94],"haemodialysis":[96],"(HD)":[97],"comorbidity":[100],"primary":[102,169],"hypothyroidism":[103],"have":[104,117],"been":[105,118],"described":[106],"[8,":[107],"9].":[108],"Moreover,":[109],"low":[110],"thyroid":[111,136,157,162],"hormones":[112],"related":[119],"higher":[122],"risk":[123],"all-cause":[128],"[10\u201314].":[130],"However,":[131],"whether":[132],"profile":[137],"caused":[139],"by":[140],"roxadustat":[141],"itself":[143],"remains":[144],"unclear.":[145],"Our":[146],"objective":[147],"was":[148],"evaluate":[150],"roxadustat/erythropoietin":[154],"(EPO)":[155],"on":[156],"stimulating":[158],"hormone":[159,163],"(TSH)":[160],"levels":[164],"without":[168],"hypothyroidism.":[170]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2025-10-10T00:00:00"}
