{"id":"https://openalex.org/W4317242548","doi":"https://doi.org/10.1055/s-0042-1760365","title":"Bleeding Risk in Elderly Patients with Venous Thromboembolism Who Would Have Been Excluded from Anticoagulation Trials","display_name":"Bleeding Risk in Elderly Patients with Venous Thromboembolism Who Would Have Been Excluded from Anticoagulation Trials","publication_year":2023,"publication_date":"2023-01-09","ids":{"openalex":"https://openalex.org/W4317242548","doi":"https://doi.org/10.1055/s-0042-1760365","pmid":"https://pubmed.ncbi.nlm.nih.gov/36649737"},"language":"en","primary_location":{"id":"doi:10.1055/s-0042-1760365","doi":"https://doi.org/10.1055/s-0042-1760365","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-0042-1760365","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0042-1760365.pdf","source":{"id":"https://openalex.org/S206235894","display_name":"Thrombosis and Haemostasis","issn_l":"0340-6245","issn":["0340-6245","2567-689X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thrombosis and Haemostasis","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0042-1760365.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032592351","display_name":"Carla Schenker","orcid":"https://orcid.org/0000-0002-4982-9157","observed_orcids":["https://orcid.org/0000-0002-4982-9157"]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]},{"id":"https://openalex.org/I2801112126","display_name":"University Hospital of Bern","ror":"https://ror.org/01q9sj412","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2801112126"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Carla Schenker","raw_affiliation_strings":["Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-4982-9157","affiliations":[{"raw_affiliation_string":"Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535","https://openalex.org/I2801112126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041523915","display_name":"Odile Stalder","orcid":"https://orcid.org/0000-0002-5563-2975","observed_orcids":["https://orcid.org/0000-0002-5563-2975"]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Odile Stalder","raw_affiliation_strings":["CTU Bern, University of Bern, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CTU Bern, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016855835","display_name":"Marie M\u00e9an","orcid":"https://orcid.org/0000-0003-0477-7899","observed_orcids":["https://orcid.org/0000-0003-0477-7899"]},"institutions":[{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I97565354","display_name":"University of Lausanne","ror":"https://ror.org/019whta54","country_code":"CH","type":"education","lineage":["https://openalex.org/I97565354"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Marie M\u00e9an","raw_affiliation_strings":["Division of Internal Medicine, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Internal Medicine, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882","https://openalex.org/I97565354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020839633","display_name":"Tobias Tritschler","orcid":"https://orcid.org/0000-0002-8775-0511","observed_orcids":["https://orcid.org/0000-0002-8775-0511"]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]},{"id":"https://openalex.org/I2801112126","display_name":"University Hospital of Bern","ror":"https://ror.org/01q9sj412","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2801112126"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Tobias Tritschler","raw_affiliation_strings":["Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535","https://openalex.org/I2801112126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031145016","display_name":"Marc Righini","orcid":"https://orcid.org/0000-0003-1211-2969","observed_orcids":["https://orcid.org/0000-0003-1211-2969"]},"institutions":[{"id":"https://openalex.org/I114457229","display_name":"University of Geneva","ror":"https://ror.org/01swzsf04","country_code":"CH","type":"education","lineage":["https://openalex.org/I114457229"]},{"id":"https://openalex.org/I4210106256","display_name":"University Hospital of Geneva","ror":"https://ror.org/01m1pv723","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210106256"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Marc Righini","raw_affiliation_strings":["Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland","institution_ids":["https://openalex.org/I114457229","https://openalex.org/I4210106256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028632973","display_name":"Nicolas Rodondi","orcid":"https://orcid.org/0000-0001-9083-6896","observed_orcids":["https://orcid.org/0000-0001-9083-6896"]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]},{"id":"https://openalex.org/I2801112126","display_name":"University Hospital of Bern","ror":"https://ror.org/01q9sj412","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2801112126"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Nicolas Rodondi","raw_affiliation_strings":["Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland","Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535","https://openalex.org/I2801112126"]},{"raw_affiliation_string":"Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027819939","display_name":"Drahomir Aujesky","orcid":"https://orcid.org/0000-0002-3970-2670","observed_orcids":["https://orcid.org/0000-0002-3970-2670"]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]},{"id":"https://openalex.org/I2801112126","display_name":"University Hospital of Bern","ror":"https://ror.org/01q9sj412","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2801112126"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Drahomir Aujesky","raw_affiliation_strings":["Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535","https://openalex.org/I2801112126"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5032592351"],"corresponding_institution_ids":["https://openalex.org/I118564535","https://openalex.org/I2801112126"],"apc_list":null,"apc_paid":null,"fwci":3.1284,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.92097264,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"123","issue":"04","first_page":"427","last_page":"437"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/venous-thromboembolism","display_name":"venous thromboembolism","score":0.9980000257492065},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.949999988079071},{"id":"https://openalex.org/keywords/trial-exclusion-criteria","display_name":"trial exclusion criteria","score":0.9039999842643738},{"id":"https://openalex.org/keywords/major-bleeding-risk","display_name":"major bleeding risk","score":0.8169999718666077},{"id":"https://openalex.org/keywords/oral-anticoagulation","display_name":"oral anticoagulation","score":0.8389999866485596},{"id":"https://openalex.org/keywords/hemodynamic-instability","display_name":"hemodynamic instability","score":0.7889999747276306},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.9279999732971191},{"id":"https://openalex.org/keywords/concomitant-medications","display_name":"concomitant medications","score":0.8970000147819519},{"id":"https://openalex.org/keywords/generalizability-of-trial-results","display_name":"generalizability of trial results","score":0.8410000205039978},{"id":"https://openalex.org/keywords/multimorbidity","display_name":"multimorbidity","score":0.5690000057220459}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.849069356918335},{"id":"https://openalex.org/C2991741193","wikidata":"https://www.wikidata.org/wiki/Q2751330","display_name":"Venous thromboembolism","level":3,"score":0.7762134075164795},{"id":"https://openalex.org/C2780011451","wikidata":"https://www.wikidata.org/wiki/Q2751330","display_name":"Venous thrombosis","level":3,"score":0.5237424373626709},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.4982776641845703},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.39666396379470825},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3775368928909302},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3409757614135742}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D001777","descriptor_name":"Blood Coagulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054556","descriptor_name":"Venous Thromboembolism","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D054556","descriptor_name":"Venous Thromboembolism","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D054556","descriptor_name":"Venous Thromboembolism","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1055/s-0042-1760365","doi":"https://doi.org/10.1055/s-0042-1760365","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-0042-1760365","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0042-1760365.pdf","source":{"id":"https://openalex.org/S206235894","display_name":"Thrombosis and Haemostasis","issn_l":"0340-6245","issn":["0340-6245","2567-689X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thrombosis and Haemostasis","raw_type":"journal-article"},{"id":"pmid:36649737","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36649737","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thrombosis and haemostasis","raw_type":"Multicenter Study"},{"id":"pmh:doi:10.48350/177607","doi":null,"is_oa":false,"landing_page_url":"https://boris-portal.unibe.ch/handle/20.500.12422/120691","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"pmh:oai:boris.unibe.ch:177607","doi":null,"is_oa":true,"landing_page_url":"https://boris.unibe.ch/177607/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401747","display_name":"BORIS (University Library Bern)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210103840","host_organization_name":"Nakuru County Council","host_organization_lineage":["https://openalex.org/I4210103840"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Schenker, Carla; Stalder, Odile; M\u00e9an, Marie; Tritschler, Tobias; Righini, Marc; Rodondi, Nicolas; Aujesky, Drahomir (2023). Bleeding Risk in Elderly Patients with Venous Thromboembolism Who Would Have Been Excluded from Anticoagulation Trials. Thrombosis and haemostasis, 123(4), pp. 427-437. Thieme 10.1055/s-0042-1760365 <http://dx.doi.org/10.1055/s-0042-1760365>","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.unil.ch:iris/69359","doi":null,"is_oa":false,"landing_page_url":"https://iris.unil.ch/handle/iris/69359","pdf_url":null,"source":{"id":"https://openalex.org/S7407055444","display_name":"IRIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"pmh:oai:serval.unil.ch:BIB_1D43CF5B1EBF","doi":null,"is_oa":false,"landing_page_url":"https://serval.unil.ch/notice/serval:BIB_1D43CF5B1EBF","pdf_url":null,"source":{"id":"https://openalex.org/S4306401797","display_name":"SERVAL (Universit\u00e9 de Lausanne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210093590","host_organization_name":"Swiss School of Archaeology in Greece","host_organization_lineage":["https://openalex.org/I4210093590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Thrombosis and haemostasis, vol. 123, no. 4, pp. 427-437","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:unige.ch:aou:unige:176408","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:176408","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Thrombosis and haemostasis, vol. 123, no. 4 (2023) p. 427-437","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1055/s-0042-1760365","doi":"https://doi.org/10.1055/s-0042-1760365","is_oa":true,"landing_page_url":"https://doi.org/10.1055/s-0042-1760365","pdf_url":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0042-1760365.pdf","source":{"id":"https://openalex.org/S206235894","display_name":"Thrombosis and Haemostasis","issn_l":"0340-6245","issn":["0340-6245","2567-689X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Thrombosis and Haemostasis","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2009282896","display_name":"The swiss venous thromboembolism cohort 65+ (SWITCO-65+)","funder_award_id":"122659","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G2314424445","display_name":null,"funder_award_id":"CDT142654","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G2957143966","display_name":null,"funder_award_id":"33CSCO","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G4905638323","display_name":null,"funder_award_id":"33CSCO-122659/139 470","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G5160772516","display_name":"The Swiss Venous Thromboembolism Cohort 65+ (SWITCO-65+)","funder_award_id":"139470","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G8374521981","display_name":null,"funder_award_id":"CDT-142654","funder_id":"https://openalex.org/F4320319880","funder_display_name":"Government of Canada"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320319880","display_name":"Government of Canada","ror":"https://ror.org/010q4q527"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320326042","display_name":"Chinese Society of Clinical Oncology","ror":"https://ror.org/05sfnze82"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4317242548.pdf","grobid_xml":"https://content.openalex.org/works/W4317242548.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W24433848","https://openalex.org/W55954674","https://openalex.org/W173036589","https://openalex.org/W338824617","https://openalex.org/W1602382091","https://openalex.org/W1634950970","https://openalex.org/W1808477918","https://openalex.org/W1875541132","https://openalex.org/W1984833612","https://openalex.org/W1991787472","https://openalex.org/W1992159512","https://openalex.org/W2005481406","https://openalex.org/W2009013630","https://openalex.org/W2010481138","https://openalex.org/W2012253653","https://openalex.org/W2012850475","https://openalex.org/W2015712245","https://openalex.org/W2016762737","https://openalex.org/W2038821159","https://openalex.org/W2038981426","https://openalex.org/W2046219226","https://openalex.org/W2068237011","https://openalex.org/W2070112905","https://openalex.org/W2070237903","https://openalex.org/W2073192852","https://openalex.org/W2112378432","https://openalex.org/W2112757583","https://openalex.org/W2114870284","https://openalex.org/W2115787552","https://openalex.org/W2118092611","https://openalex.org/W2127390813","https://openalex.org/W2130199362","https://openalex.org/W2135918458","https://openalex.org/W2138438886","https://openalex.org/W2138845401","https://openalex.org/W2139511461","https://openalex.org/W2139785591","https://openalex.org/W2156320702","https://openalex.org/W2159553511","https://openalex.org/W2160625453","https://openalex.org/W2166402206","https://openalex.org/W2166437990","https://openalex.org/W2169472792","https://openalex.org/W2170206601","https://openalex.org/W2225937646","https://openalex.org/W2316248832","https://openalex.org/W2327974959","https://openalex.org/W2331935930","https://openalex.org/W2332640098","https://openalex.org/W2340468754","https://openalex.org/W2568332688","https://openalex.org/W2731095182","https://openalex.org/W2989714602","https://openalex.org/W3090209681","https://openalex.org/W3159625960"],"related_works":["https://openalex.org/W4225924387","https://openalex.org/W1882582463","https://openalex.org/W2038821159","https://openalex.org/W6902817177","https://openalex.org/W1998784396","https://openalex.org/W4312082619","https://openalex.org/W1991787472","https://openalex.org/W6940133019","https://openalex.org/W4375847445","https://openalex.org/W4387472720"],"abstract_inverted_index":{"Older":[0],"patients":[1,18,41,88,143,206],"with":[2,19,45,178,185,223],"venous":[3],"thromboembolism":[4],"(VTE)":[5],"are":[6],"underrepresented":[7],"in":[8,48,150,213],"clinical":[9],"anticoagulation":[10,59,216],"trials.":[11,153,217],"We":[12,38,53,97],"examined":[13,98],"to":[14,181,239],"which":[15],"extent":[16],"elderly":[17],"VTE":[20,47,57,215],"would":[21,90,144,207],"be":[22,209,237],"excluded":[23,34,93,147],"from":[24,61,94,148,232],"such":[25,233],"trials":[26,60,234],"and":[27,35,64,81,113,116,131,169,242],"compared":[28],"the":[29,62,78,83,99,151,224],"bleeding":[30,109,118,219],"risk":[31,125,198,220],"between":[32,101],"hypothetically":[33],"enrolled":[36],"patients.":[37,244],"studied":[39],"991":[40],"aged":[42],"\u226565":[43],"years":[44],"acute":[46],"a":[49,190],"prospective":[50],"multicenter":[51],"cohort.":[52],"identified":[54],"12":[55],"landmark":[56,152],"oral":[58],"eighth":[63],"updated":[65],"ninth":[66],"American":[67],"College":[68],"of":[69,85,133,137,141,199,204,226],"Chest":[70],"Physician":[71],"Guidelines.":[72],"For":[73],"each":[74],"trial,":[75],"we":[76],"abstracted":[77],"exclusion":[79,104,187,227],"criteria":[80,105,188,228],"calculated":[82],"proportion":[84],"our":[86,142],"study":[87],"who":[89],"have":[91,145],"been":[92,146],"trial":[95],"participation.":[96],"association":[100],"five":[102],"common":[103],"(hemodynamic":[106],"instability,":[107],"high":[108],"risk,":[110],"comorbidity,":[111],"co-medication,":[112],"invasive":[114],"treatments)":[115],"major":[117],"(MB)":[119],"within":[120],"36":[121],"months":[122],"using":[123],"competing":[124],"regression,":[126],"adjusting":[127],"for":[128,211],"age,":[129],"sex,":[130],"periods":[132],"anticoagulation.":[134],"A":[135],"median":[136],"31%":[138],"(range:":[139],"20-52%)":[140],"participation":[149,212],"Hemodynamic":[154],"instability":[155],"(sub-hazard":[156],"ratio":[157],"[SHR]:":[158],"2.2,":[159],"95%":[160,166,173,194],"CI:":[161,167,174,195],"1.1-4.7),":[162],"comorbidity":[163],"(SHR:":[164,171,192],"1.5,":[165,172],"1.1-2.2),":[168],"co-medication":[170],"1.0-2.3)":[175],"were":[176],"associated":[177],"MB.":[179,200],"Compared":[180],"eligible":[182,210],"patients,":[183],"those":[184],"\u22652":[186],"had":[189],"twofold":[191],"2.16,":[193],"1.38-3.39)":[196],"increased":[197],"Overall,":[201],"about":[202],"one-third":[203],"older":[205],"not":[208,236],"guideline-defining":[214],"The":[218],"increases":[221],"significantly":[222],"number":[225],"present.":[229],"Thus,":[230],"results":[231],"may":[235],"generalizable":[238],"older,":[240],"multimorbid,":[241],"co-medicated":[243]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-01-18T00:00:00"}