{"id":"https://openalex.org/W4313895309","doi":"https://doi.org/10.1158/1538-7755.disp22-c088","title":"Abstract C088: Biological and neighborhood-level social determinants of prostate disease aggressiveness among Black and White men undergoing prostate biopsy","display_name":"Abstract C088: Biological and neighborhood-level social determinants of prostate disease aggressiveness among Black and White men undergoing prostate biopsy","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4313895309","doi":"https://doi.org/10.1158/1538-7755.disp22-c088"},"language":"en","primary_location":{"id":"doi:10.1158/1538-7755.disp22-c088","doi":"https://doi.org/10.1158/1538-7755.disp22-c088","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1158/1538-7755.disp22-c088","pdf_url":null,"source":{"id":"https://openalex.org/S8391440","display_name":"Cancer Epidemiology Biomarkers & Prevention","issn_l":"1055-9965","issn":["1055-9965","1538-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Epidemiology, Biomarkers & Prevention","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044120624","display_name":"Jennifer C. Cullen","orcid":"https://orcid.org/0000-0002-2123-416X","observed_orcids":["https://orcid.org/0000-0002-2123-416X"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer Cullen","raw_affiliation_strings":["1Case Western Reserve University, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Case Western Reserve University, Cleveland, OH,","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100338124","display_name":"Tao Liu","orcid":"https://orcid.org/0000-0002-9943-2131","observed_orcids":["https://orcid.org/0000-0002-9943-2131"]},"institutions":[{"id":"https://openalex.org/I142606810","display_name":"Pacific Northwest National Laboratory","ror":"https://ror.org/05h992307","country_code":"US","type":"facility","lineage":["https://openalex.org/I1325736334","https://openalex.org/I1330989302","https://openalex.org/I142606810","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tao Liu","raw_affiliation_strings":["2Pacific Northwest National Laboratory, Richland, WA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Pacific Northwest National Laboratory, Richland, WA,","institution_ids":["https://openalex.org/I142606810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077382678","display_name":"Karin Rodland","orcid":"https://orcid.org/0000-0001-7070-6541","observed_orcids":["https://orcid.org/0000-0001-7070-6541"]},"institutions":[{"id":"https://openalex.org/I142606810","display_name":"Pacific Northwest National Laboratory","ror":"https://ror.org/05h992307","country_code":"US","type":"facility","lineage":["https://openalex.org/I1325736334","https://openalex.org/I1330989302","https://openalex.org/I142606810","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karin Rodland","raw_affiliation_strings":["2Pacific Northwest National Laboratory, Richland, WA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Pacific Northwest National Laboratory, Richland, WA,","institution_ids":["https://openalex.org/I142606810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024887790","display_name":"Ranjini Ghosh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ranjini Ghosh","raw_affiliation_strings":["1Case Western Reserve University, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Case Western Reserve University, Cleveland, OH,","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001485911","display_name":"Anood Alfamy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799343972","display_name":"University Hospitals of Cleveland","ror":"https://ror.org/0130jk839","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anood Alfamy","raw_affiliation_strings":["3University Hospitals, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3University Hospitals, Cleveland, OH,","institution_ids":["https://openalex.org/I2799343972"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101922908","display_name":"Julia Yang Payne","orcid":"https://orcid.org/0000-0002-9518-8709","observed_orcids":["https://orcid.org/0000-0002-9518-8709"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julia Payne","raw_affiliation_strings":["1Case Western Reserve University, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Case Western Reserve University, Cleveland, OH,","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022843853","display_name":"Kirsten Yuna Eom","orcid":"https://orcid.org/0000-0003-3809-2978","observed_orcids":["https://orcid.org/0000-0003-3809-2978"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kirsten Eom","raw_affiliation_strings":["1Case Western Reserve University, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Case Western Reserve University, Cleveland, OH,","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047980444","display_name":"Sweta Balaji","orcid":"https://orcid.org/0009-0005-5802-5897","observed_orcids":["https://orcid.org/0009-0005-5802-5897"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sweta Balaji","raw_affiliation_strings":["4Emory University, Atlanta, GA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Emory University, Atlanta, GA,","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nicole Diaz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I64281891","display_name":"The College of New Jersey","ror":"https://ror.org/02nx5r318","country_code":"US","type":"education","lineage":["https://openalex.org/I64281891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole Diaz","raw_affiliation_strings":["5College of New Jersey, Ewing Township, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"5College of New Jersey, Ewing Township, NJ","institution_ids":["https://openalex.org/I64281891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084300565","display_name":"Holly E. Hartman","orcid":"https://orcid.org/0000-0002-9101-4381","observed_orcids":["https://orcid.org/0000-0002-9101-4381"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Holly Hartman","raw_affiliation_strings":["1Case Western Reserve University, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Case Western Reserve University, Cleveland, OH,","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089426435","display_name":"Annie Liang Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799343972","display_name":"University Hospitals of Cleveland","ror":"https://ror.org/0130jk839","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Annie Liang Zhang","raw_affiliation_strings":["3University Hospitals, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3University Hospitals, Cleveland, OH,","institution_ids":["https://openalex.org/I2799343972"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076238068","display_name":"Daniel Eidelberg Spratt","orcid":"https://orcid.org/0000-0002-5973-4741","observed_orcids":["https://orcid.org/0000-0002-5973-4741"]},"institutions":[{"id":"https://openalex.org/I2799343972","display_name":"University Hospitals of Cleveland","ror":"https://ror.org/0130jk839","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Spratt","raw_affiliation_strings":["3University Hospitals, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3University Hospitals, Cleveland, OH,","institution_ids":["https://openalex.org/I2799343972"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042458087","display_name":"Jonathan Evan Shoag","orcid":"https://orcid.org/0000-0002-3119-9986","observed_orcids":["https://orcid.org/0000-0002-3119-9986"]},"institutions":[{"id":"https://openalex.org/I2799343972","display_name":"University Hospitals of Cleveland","ror":"https://ror.org/0130jk839","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan Shoag","raw_affiliation_strings":["3University Hospitals, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3University Hospitals, Cleveland, OH,","institution_ids":["https://openalex.org/I2799343972"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013356755","display_name":"Erika Trapl","orcid":"https://orcid.org/0000-0002-5021-8505","observed_orcids":["https://orcid.org/0000-0002-5021-8505"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erika Trapl","raw_affiliation_strings":["1Case Western Reserve University, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Case Western Reserve University, Cleveland, OH,","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018694224","display_name":"Lee Evan Ponsky","orcid":"https://orcid.org/0000-0002-1252-3285","observed_orcids":["https://orcid.org/0000-0002-1252-3285"]},"institutions":[{"id":"https://openalex.org/I2799343972","display_name":"University Hospitals of Cleveland","ror":"https://ror.org/0130jk839","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lee Ponsky","raw_affiliation_strings":["3University Hospitals, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3University Hospitals, Cleveland, OH,","institution_ids":["https://openalex.org/I2799343972"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009444072","display_name":"Gregory T. MacLennan","orcid":"https://orcid.org/0000-0001-6171-2042","observed_orcids":["https://orcid.org/0000-0001-6171-2042"]},"institutions":[{"id":"https://openalex.org/I2799343972","display_name":"University Hospitals of Cleveland","ror":"https://ror.org/0130jk839","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory MacLennan","raw_affiliation_strings":["3University Hospitals, Cleveland, OH,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3University Hospitals, Cleveland, OH,","institution_ids":["https://openalex.org/I2799343972"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"1_Supplement","first_page":"C088","last_page":"C088"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9413999915122986,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9413999915122986,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.0421999990940094,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10235","display_name":"Health disparities and outcomes","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/3306","display_name":"Health"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9380000233650208},{"id":"https://openalex.org/keywords/tumor-aggressiveness","display_name":"tumor aggressiveness","score":0.8240000009536743},{"id":"https://openalex.org/keywords/social-determinants-of-health","display_name":"social determinants of health","score":0.8859999775886536},{"id":"https://openalex.org/keywords/racial-disparities","display_name":"racial disparities","score":0.8149999976158142},{"id":"https://openalex.org/keywords/black-men","display_name":"Black men","score":0.968999981880188},{"id":"https://openalex.org/keywords/gleason-score","display_name":"Gleason score","score":0.7860000133514404},{"id":"https://openalex.org/keywords/metastatic-prostate-cancer","display_name":"metastatic prostate cancer","score":0.8899999856948853},{"id":"https://openalex.org/keywords/prostate-biopsy","display_name":"prostate biopsy","score":0.7009999752044678},{"id":"https://openalex.org/keywords/proteomic-biomarkers","display_name":"proteomic biomarkers","score":0.7590000033378601},{"id":"https://openalex.org/keywords/prostate-cancer-risk-prediction","display_name":"prostate cancer risk prediction","score":0.375},{"id":"https://openalex.org/keywords/overtreatment-avoidance","display_name":"overtreatment avoidance","score":0.6959999799728394},{"id":"https://openalex.org/keywords/transrectal-ultrasound-guided-biopsy","display_name":"transrectal ultrasound-guided biopsy","score":0.7099999785423279},{"id":"https://openalex.org/keywords/multilevel-modeling","display_name":"multilevel modeling","score":0.4830000102519989},{"id":"https://openalex.org/keywords/cleveland","display_name":"Cleveland (Ohio)","score":0.4909999966621399}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8299446105957031},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.808366060256958},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.6698344945907593},{"id":"https://openalex.org/C2781217009","wikidata":"https://www.wikidata.org/wiki/Q4086927","display_name":"Prostate biopsy","level":4,"score":0.6257688999176025},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5854793787002563},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5072919726371765},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4948500990867615},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.4803822636604309},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.4748680293560028},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.45968198776245117},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37165337800979614},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.36707329750061035},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3599138855934143},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1538-7755.disp22-c088","doi":"https://doi.org/10.1158/1538-7755.disp22-c088","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1158/1538-7755.disp22-c088","pdf_url":null,"source":{"id":"https://openalex.org/S8391440","display_name":"Cancer Epidemiology Biomarkers & Prevention","issn_l":"1055-9965","issn":["1055-9965","1538-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Epidemiology, Biomarkers & Prevention","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0},{"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities","score":0.8974000215530396}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4389228061","https://openalex.org/W4402708430","https://openalex.org/W1993198172","https://openalex.org/W3126257414","https://openalex.org/W2087827544","https://openalex.org/W3094480220","https://openalex.org/W2093349182","https://openalex.org/W2565189910","https://openalex.org/W2404404312","https://openalex.org/W2168706445"],"abstract_inverted_index":{"Abstract":[0],"Introduction":[1],"and":[2,16,32,71,77,107,112,172,198,211,223,233,300,322,335,364,374,394,470,480,504],"study":[3,103,140,278,287],"purpose:":[4],"Prostate":[5],"cancer":[6,15,21,219,361,392,406,432],"(PCa)":[7],"is":[8,88,98,240],"the":[9,38,105,144,154,183,246,316,329,368,415,490,495,505],"leading":[10,18],"type":[11],"of":[12,20,48,81,84,93,110,115,128,134,193,201,207,237,265,284,289,360,396,405,474,489,497],"newly":[13],"diagnosed":[14],"second":[17],"cause":[19],"death":[22],"in":[23,29,37,58,118,123,150,269,408,501],"American":[24],"men.":[25,53,79,332],"Significant":[26],"racial":[27],"differences":[28],"PCa":[30,67,73,206,214],"incidence":[31],"mortality":[33],"have":[34,64,312,325,414],"been":[35,313,326],"long-reported":[36],"U.S.,":[39],"with":[40,190,215,271,293,342,410],"Black":[41,78,173,479],"men":[42,129,174,292,319,482],"demonstrating":[43],"a":[44,124,191,263,286],"disproportionately":[45],"higher":[46],"burden":[47],"disease":[49,86,96,121,260,372,476],"compared":[50],"to":[51,90,100,166,257,328,344,370,380,417,430],"White":[52,76,171,481],"Though":[54],"some":[55],"studies":[56],"conducted":[57,142,165,256],"equal":[59],"access":[60],"health":[61,116],"care":[62],"settings":[63],"revealed":[65],"equivalent":[66],"characteristics":[68],"at":[69,143,217,245],"diagnosis":[70],"comparable":[72],"outcomes":[74,393],"for":[75,132,153,304],"Identification":[80],"early":[82],"predictors":[83],"prostate":[85,120,202,259,391,475,484],"aggressiveness":[87,122,261,362,477],"essential":[89],"avoid":[91],"over-treatment":[92],"clinically":[94],"favorably":[95],"that":[97,400],"unlikely":[99],"progress.":[101],"This":[102,277],"examines":[104],"independent":[106],"joint":[108],"roles":[109],"biological":[111,224,403],"social":[113,412,472],"determinants":[114,404,473],"(SDOHs)":[117],"predicting":[119],"racially":[125],"diverse":[126],"cohort":[127,139,288],"undergoing":[130,175,483],"biopsy":[131,178,180,189,196,238,295,351,354,485],"suspicion":[133],"PCa.":[135],"Methodology:":[136],"A":[137,160],"retrospective":[138,161,230],"was":[141,164],"University":[145],"Hospitals":[146],"Seidman":[147],"Cancer":[148,498,516],"Center":[149],"Cleveland,":[151],"Ohio":[152],"period":[155],"January":[156],"1,":[157],"2005-May":[158],"2022.":[159],"chart":[162,231],"review":[163],"identify":[167,375],"eligible":[168,291],"men,":[169],"including":[170],"transrectal":[176],"ultrasound-guided":[177],"whose":[179],"results":[181],"included":[182],"following":[184],"3":[185],"groups:":[186],"(i)":[187],"negative":[188,195],"history":[192,200],"1+":[194],"(-ies)":[197],"no":[199],"cancer;":[203],"(ii)":[204],"biopsy-detected":[205,213],"Gleason":[208,352],"sum":[209],"6;":[210],"(iii)":[212],"metastases":[216],"initial":[218,282],"detection.":[220],"Detailed":[221],"clinical":[222,298,347],"specimen":[225],"data":[226,311,337],"were":[227],"abstracted":[228],"during":[229],"review,":[232],"quantitative":[234],"proteomics":[235,310],"analysis":[236],"tissues":[239],"ongoing,":[241],"using":[242],"mass":[243],"spectrometry,":[244],"Pacific":[247],"Northwest":[248],"National":[249],"Laboratory":[250],"(PNNL).":[251],"Multi-level":[252],"modeling":[253,399],"will":[254,338,388],"be":[255,339,421],"predict":[258,345],"as":[262,426,428],"function":[264],"protein":[266],"biomarker":[267],"candidates":[268],"combination":[270],"census":[272,306],"block":[273],"group-level":[274],"SDOHs.":[275],"Results:":[276],"has":[279,367],"achieved":[280],"its":[281],"goal":[283],"assembling":[285],"300":[290],"available":[294],"tissue,":[296],"necessary":[297],"information,":[299],"full":[301],"street":[302],"address":[303],"assigning":[305],"regions.":[307],"To":[308],"date,":[309],"generated":[314],"on":[315,494],"first":[317,330],"60":[318],"(\u201cDiscovery":[320],"cohort\u201d)":[321],"SDOHs":[323,343],"metrics":[324],"linked":[327],"180":[331],"Proteomic":[333],"profiles":[334],"SDOH":[336],"examined":[340],"jointly":[341,401],"patient":[346],"phenotype":[348],"(i.e.,":[349],"metastatic,":[350],"6,":[353],"negative).":[355],"Conclusions:":[356],"Identifying":[357],"new":[358],"markers":[359],"within":[363],"across":[365],"race":[366],"potential":[369,416],"tailor":[371],"management,":[373],"patients":[376],"who":[377,419],"are":[378],"likely":[379],"benefit":[381],"from":[382],"earlier,":[383],"timely":[384],"treatment":[385],"interventions,":[386],"which":[387],"ultimately":[389],"improve":[390],"quality":[395],"life.":[397],"Predictive":[398],"considers":[402],"disparities":[407],"conjunction":[409],"neighborhood-level":[411,471],"factors":[413],"elucidate":[418],"can":[420],"safely":[422],"spared":[423],"repeat":[424],"biopsies,":[425],"well":[427],"how":[429],"optimize":[431],"care.":[433],"Citation":[434],"Format:":[435],"Jennifer":[436],"Cullen,":[437],"Tao":[438],"Liu,":[439],"Karin":[440],"Rodland,":[441],"Ranjini":[442],"Ghosh,":[443],"Anood":[444],"Alfamy,":[445],"Julia":[446],"Payne,":[447],"Kirsten":[448],"Eom,":[449],"Sweta":[450],"Balaji,":[451],"Nicole":[452],"Diaz,":[453],"Holly":[454],"Hartman,":[455],"Annie":[456],"Liang":[457],"Zhang,":[458],"Daniel":[459],"Spratt,":[460],"Jonathan":[461],"Shoag,":[462],"Erika":[463],"Trapl,":[464],"Lee":[465],"Ponsky,":[466],"Gregory":[467],"MacLennan.":[468],"Biological":[469],"among":[478],"[abstract].":[486],"In:":[487],"Proceedings":[488],"15th":[491],"AACR":[492],"Conference":[493],"Science":[496],"Health":[499],"Disparities":[500],"Racial/Ethnic":[502],"Minorities":[503],"Medically":[506],"Underserved;":[507],"2022":[508],"Sep":[509],"16-19;":[510],"Philadelphia,":[511],"PA.":[512],"Philadelphia":[513],"(PA):":[514],"AACR;":[515],"Epidemiol":[517],"Biomarkers":[518],"Prev":[519],"2022;31(1":[520],"Suppl):Abstract":[521],"nr":[522],"C088.":[523]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2023-01-10T00:00:00"}