{"id":"https://openalex.org/W4313646396","doi":"https://doi.org/10.3390/pathogens12010092","title":"Role of TLRs in HIV-1 Infection and Potential of TLR Agonists in HIV-1 Vaccine Development and Treatment Strategies","display_name":"Role of TLRs in HIV-1 Infection and Potential of TLR Agonists in HIV-1 Vaccine Development and Treatment Strategies","publication_year":2023,"publication_date":"2023-01-05","ids":{"openalex":"https://openalex.org/W4313646396","doi":"https://doi.org/10.3390/pathogens12010092","pmid":"https://pubmed.ncbi.nlm.nih.gov/36678440","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9866513"},"language":"en","primary_location":{"id":"doi:10.3390/pathogens12010092","doi":"https://doi.org/10.3390/pathogens12010092","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pathogens12010092","pdf_url":"https://www.mdpi.com/2076-0817/12/1/92/pdf?version=1673947499","source":{"id":"https://openalex.org/S4210239906","display_name":"Pathogens","issn_l":"2076-0817","issn":["2076-0817"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathogens","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2076-0817/12/1/92/pdf?version=1673947499","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047057376","display_name":"Marija Rozman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133779","display_name":"University Hospital for Infectious Diseases \"Dr Fran Mihaljevic\"","ror":"https://ror.org/040896072","country_code":"HR","type":"healthcare","lineage":["https://openalex.org/I4210133779"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Marija Rozman","raw_affiliation_strings":["Department of Immunological and Molecular Diagnostics, University Hospital for Infectious Diseases Zagreb, 10000 Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunological and Molecular Diagnostics, University Hospital for Infectious Diseases Zagreb, 10000 Zagreb, Croatia","institution_ids":["https://openalex.org/I4210133779"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030807436","display_name":"Snje\u017eana \u017didovec Lepej","orcid":"https://orcid.org/0000-0001-9852-5806","observed_orcids":["https://orcid.org/0000-0001-9852-5806"]},"institutions":[{"id":"https://openalex.org/I4210133779","display_name":"University Hospital for Infectious Diseases \"Dr Fran Mihaljevic\"","ror":"https://ror.org/040896072","country_code":"HR","type":"healthcare","lineage":["https://openalex.org/I4210133779"]}],"countries":["HR"],"is_corresponding":true,"raw_author_name":"Snjezana Zidovec-Lepej","raw_affiliation_strings":["Department of Immunological and Molecular Diagnostics, University Hospital for Infectious Diseases Zagreb, 10000 Zagreb, Croatia"],"raw_orcid":"https://orcid.org/0000-0001-9852-5806","affiliations":[{"raw_affiliation_string":"Department of Immunological and Molecular Diagnostics, University Hospital for Infectious Diseases Zagreb, 10000 Zagreb, Croatia","institution_ids":["https://openalex.org/I4210133779"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029402834","display_name":"Karlo Jambrosic","orcid":"https://orcid.org/0000-0001-7103-6295","observed_orcids":["https://orcid.org/0000-0001-7103-6295"]},"institutions":[{"id":"https://openalex.org/I4210123216","display_name":"Ru\u0111er Bo\u0161kovi\u0107 Institute","ror":"https://ror.org/02mw21745","country_code":"HR","type":"facility","lineage":["https://openalex.org/I4210123216"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Karlo Jambrosic","raw_affiliation_strings":["Laboratory for Analytical Chemistry and Biogeochemistry of Organic Compounds, Division for Marine and Environmental Research, Ruder Boskovic Institute, 10000 Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Analytical Chemistry and Biogeochemistry of Organic Compounds, Division for Marine and Environmental Research, Ruder Boskovic Institute, 10000 Zagreb, Croatia","institution_ids":["https://openalex.org/I4210123216"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101193060","display_name":"Maja Babi\u0107","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089068","display_name":"Children's Hospital Srebrnjak","ror":"https://ror.org/008sqe405","country_code":"HR","type":"healthcare","lineage":["https://openalex.org/I4210089068"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Maja Babi\u0107","raw_affiliation_strings":["Srebrnjak Children\u2019s Hospital, 10000 Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Srebrnjak Children\u2019s Hospital, 10000 Zagreb, Croatia","institution_ids":["https://openalex.org/I4210089068"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042283406","display_name":"Irena Drmi\u0107 Hofman","orcid":"https://orcid.org/0000-0002-4986-9589","observed_orcids":["https://orcid.org/0000-0002-4986-9589"]},"institutions":[{"id":"https://openalex.org/I92251255","display_name":"University of Split","ror":"https://ror.org/00m31ft63","country_code":"HR","type":"education","lineage":["https://openalex.org/I92251255"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Irena Drmi\u0107 Hofman","raw_affiliation_strings":["Department of Health Studies, University of Split, 21000 Split, Croatia","School of Medicine, University of Split, 21000 Split, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Studies, University of Split, 21000 Split, Croatia","institution_ids":["https://openalex.org/I92251255"]},{"raw_affiliation_string":"School of Medicine, University of Split, 21000 Split, Croatia","institution_ids":["https://openalex.org/I92251255"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5030807436"],"corresponding_institution_ids":["https://openalex.org/I4210133779"],"apc_list":{"value":2200,"currency":"CHF","value_usd":2447},"apc_paid":{"value":2200,"currency":"CHF","value_usd":2447},"fwci":0.7584,"has_fulltext":true,"cited_by_count":23,"citation_normalized_percentile":{"value":0.58248175,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"12","issue":"1","first_page":"92","last_page":"92"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.6723999977111816,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.6723999977111816,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.32010000944137573,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/toll-like-receptors","display_name":"Toll-like receptors","score":0.9760000109672546},{"id":"https://openalex.org/keywords/hiv-1-infection","display_name":"HIV-1 infection","score":0.9679999947547913},{"id":"https://openalex.org/keywords/tlr7","display_name":"TLR7","score":0.8880000114440918},{"id":"https://openalex.org/keywords/tlr8","display_name":"TLR8","score":1.0},{"id":"https://openalex.org/keywords/innate-immune-response","display_name":"innate immune response","score":0.9279999732971191},{"id":"https://openalex.org/keywords/toll-like-receptor-agonists","display_name":"TLR agonists","score":0.9070000052452087},{"id":"https://openalex.org/keywords/latency-reversing-agents","display_name":"latency-reversing agents","score":0.8259999752044678},{"id":"https://openalex.org/keywords/hiv-vaccine-development","display_name":"HIV vaccine development","score":0.7799999713897705},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.8360000252723694},{"id":"https://openalex.org/keywords/interferon","display_name":"interferon","score":0.7950000166893005},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.7860000133514404},{"id":"https://openalex.org/keywords/chemokines","display_name":"chemokines","score":0.8379999995231628}],"concepts":[{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.7673547863960266},{"id":"https://openalex.org/C2779836521","wikidata":"https://www.wikidata.org/wiki/Q14914081","display_name":"TLR7","level":5,"score":0.6963924169540405},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6402686834335327},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6083582043647766},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6019057631492615},{"id":"https://openalex.org/C111289621","wikidata":"https://www.wikidata.org/wiki/Q418772","display_name":"Pattern recognition receptor","level":4,"score":0.5564699172973633},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.5504435896873474},{"id":"https://openalex.org/C193419808","wikidata":"https://www.wikidata.org/wiki/Q1645075","display_name":"Acquired immune system","level":3,"score":0.5236989259719849},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.5038918852806091},{"id":"https://openalex.org/C2778420691","wikidata":"https://www.wikidata.org/wiki/Q14866230","display_name":"TLR3","level":5,"score":0.46500787138938904},{"id":"https://openalex.org/C2776709828","wikidata":"https://www.wikidata.org/wiki/Q408004","display_name":"Toll-like receptor","level":4,"score":0.4205821752548218},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.2081088125705719}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/pathogens12010092","doi":"https://doi.org/10.3390/pathogens12010092","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pathogens12010092","pdf_url":"https://www.mdpi.com/2076-0817/12/1/92/pdf?version=1673947499","source":{"id":"https://openalex.org/S4210239906","display_name":"Pathogens","issn_l":"2076-0817","issn":["2076-0817"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathogens","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9866513","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9866513","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9866513/pdf/pathogens-12-00092.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathogens","raw_type":"Text"},{"id":"pmid:36678440","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36678440","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathogens (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:235a9977a3be41a6b9e50fbd1bf74ebf","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/235a9977a3be41a6b9e50fbd1bf74ebf","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pathogens, Vol 12, Iss 1, p 92 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/pathogens12010092","doi":"https://doi.org/10.3390/pathogens12010092","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pathogens12010092","pdf_url":"https://www.mdpi.com/2076-0817/12/1/92/pdf?version=1673947499","source":{"id":"https://openalex.org/S4210239906","display_name":"Pathogens","issn_l":"2076-0817","issn":["2076-0817"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathogens","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1042398408","display_name":null,"funder_award_id":"IP-2019-04","funder_id":"https://openalex.org/F4320322674","funder_display_name":"Hrvatska Zaklada za Znanost"},{"id":"https://openalex.org/G7580243016","display_name":"Molecular epidemiology, clinical features and care for HIV infection in Croatia","funder_award_id":"IP-2019-04-9702","funder_id":"https://openalex.org/F4320322674","funder_display_name":"Hrvatska Zaklada za Znanost"}],"funders":[{"id":"https://openalex.org/F4320322674","display_name":"Hrvatska Zaklada za Znanost","ror":"https://ror.org/03n51vw80"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4313646396.pdf","grobid_xml":"https://content.openalex.org/works/W4313646396.grobid-xml"},"referenced_works_count":109,"referenced_works":["https://openalex.org/W1921065457","https://openalex.org/W1929740795","https://openalex.org/W1971045102","https://openalex.org/W1971749790","https://openalex.org/W1972658532","https://openalex.org/W1977282539","https://openalex.org/W1998924155","https://openalex.org/W1999908288","https://openalex.org/W2011560892","https://openalex.org/W2027555120","https://openalex.org/W2032136448","https://openalex.org/W2032349776","https://openalex.org/W2033023829","https://openalex.org/W2040950036","https://openalex.org/W2045303929","https://openalex.org/W2056056969","https://openalex.org/W2057121293","https://openalex.org/W2060731298","https://openalex.org/W2061919488","https://openalex.org/W2076965602","https://openalex.org/W2084901266","https://openalex.org/W2087085784","https://openalex.org/W2103236172","https://openalex.org/W2103644250","https://openalex.org/W2124058652","https://openalex.org/W2140692786","https://openalex.org/W2142563401","https://openalex.org/W2146915650","https://openalex.org/W2163400707","https://openalex.org/W2187165435","https://openalex.org/W2257036949","https://openalex.org/W2277732086","https://openalex.org/W2289411371","https://openalex.org/W2321198083","https://openalex.org/W2507772654","https://openalex.org/W2531711570","https://openalex.org/W2532843373","https://openalex.org/W2556485149","https://openalex.org/W2559987954","https://openalex.org/W2568275404","https://openalex.org/W2583390195","https://openalex.org/W2586226836","https://openalex.org/W2625924212","https://openalex.org/W2724336500","https://openalex.org/W2736913840","https://openalex.org/W2753602919","https://openalex.org/W2763252130","https://openalex.org/W2782696110","https://openalex.org/W2802298459","https://openalex.org/W2804475258","https://openalex.org/W2888061414","https://openalex.org/W2895775323","https://openalex.org/W2897382519","https://openalex.org/W2914234121","https://openalex.org/W2916311731","https://openalex.org/W2922370077","https://openalex.org/W2947901838","https://openalex.org/W2948742834","https://openalex.org/W2949588730","https://openalex.org/W2953226631","https://openalex.org/W2981099228","https://openalex.org/W2995764816","https://openalex.org/W2999714040","https://openalex.org/W3000848632","https://openalex.org/W3010724614","https://openalex.org/W3027081111","https://openalex.org/W3030947224","https://openalex.org/W3034135365","https://openalex.org/W3037408845","https://openalex.org/W3042850686","https://openalex.org/W3047396241","https://openalex.org/W3081460628","https://openalex.org/W3091821209","https://openalex.org/W3093206135","https://openalex.org/W3094512991","https://openalex.org/W3094796225","https://openalex.org/W3114535748","https://openalex.org/W3116055976","https://openalex.org/W3126899606","https://openalex.org/W3127703261","https://openalex.org/W3130573814","https://openalex.org/W3171542315","https://openalex.org/W3176951336","https://openalex.org/W3182628359","https://openalex.org/W3193445073","https://openalex.org/W3197050679","https://openalex.org/W3200104592","https://openalex.org/W3201428527","https://openalex.org/W3207834414","https://openalex.org/W3209298539","https://openalex.org/W3213641937","https://openalex.org/W4200262458","https://openalex.org/W4206274130","https://openalex.org/W4211228105","https://openalex.org/W4213338480","https://openalex.org/W4214925106","https://openalex.org/W4221119825","https://openalex.org/W4223578260","https://openalex.org/W4224289637","https://openalex.org/W4225140243","https://openalex.org/W4280546036","https://openalex.org/W4280563628","https://openalex.org/W4283019102","https://openalex.org/W4283323163","https://openalex.org/W4283783402","https://openalex.org/W4308015009","https://openalex.org/W6686825414","https://openalex.org/W6692126850","https://openalex.org/W6784578353"],"related_works":["https://openalex.org/W3030947224","https://openalex.org/W3023759969","https://openalex.org/W4379232800","https://openalex.org/W1547593654","https://openalex.org/W7097626513","https://openalex.org/W1892879898","https://openalex.org/W4318200443","https://openalex.org/W2914369390","https://openalex.org/W3000658405","https://openalex.org/W1485326960"],"abstract_inverted_index":{"Toll-like":[0],"receptors":[1],"(TLRs),":[2],"as":[3,137,148],"a":[4,32,45],"family":[5],"of":[6,17,24,38,76,90,103,115,127,134],"pattern":[7],"recognition":[8,16],"receptors,":[9],"play":[10,44],"an":[11],"important":[12,47],"role":[13,48,102,114,133],"in":[14,49,74,105,119,123,141,150],"the":[15,25,50,96,101,106,113,120,124,132],"HIV-1":[18,111],"molecular":[19],"structures":[20],"by":[21],"various":[22,80],"cells":[23],"innate":[26,51,107],"immune":[27,52,108],"system,":[28],"but":[29],"also":[30],"provide":[31],"functional":[33],"association":[34],"with":[35],"subsequent":[36],"mechanisms":[37],"adaptive":[39],"immunity.":[40],"TLR7":[41],"and":[42,67,112,122,147],"TLR8":[43],"particularly":[46],"response":[53,82,109],"to":[54,58,61,94,110,143],"RNA":[55,65],"viruses":[56],"due":[57],"their":[59],"ability":[60],"recognise":[62],"GU-rich":[63],"single-stranded":[64],"molecules":[66],"subsequently":[68],"activate":[69],"intracellular":[70],"signalling":[71],"pathways":[72],"resulting":[73],"expression":[75],"genes":[77],"coding":[78],"for":[79],"biological":[81],"modifiers":[83],"(interferons,":[84],"proinflammatory":[85],"cytokines,":[86],"chemokines).":[87],"The":[88],"aim":[89],"this":[91],"review":[92],"is":[93],"summarise":[95],"most":[97],"recent":[98],"knowledge":[99],"on":[100],"TLRs":[104],"TLR":[116,135],"gene":[117],"polymorphisms":[118],"biology":[121],"clinical":[125],"aspects":[126],"HIV":[128,145,151],"infections.":[129],"In":[130],"addition,":[131],"agonists":[136],"latency":[138],"reversing":[139],"agents":[140],"research":[142,153],"treat":[144],"infections":[146],"immunomodulators":[149],"vaccine":[152],"will":[154],"be":[155],"discussed.":[156]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":5}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2023-01-07T00:00:00"}