{"id":"https://openalex.org/W4313386497","doi":"https://doi.org/10.4049/jimmunol.190.supp.114.15","title":"Intracellular free Mg2+ is required to maintain NKG2D expression necessary for controlling EBV infection in XMEN disease (P3028)","display_name":"Intracellular free Mg2+ is required to maintain NKG2D expression necessary for controlling EBV infection in XMEN disease (P3028)","publication_year":2013,"publication_date":"2013-05-01","ids":{"openalex":"https://openalex.org/W4313386497","doi":"https://doi.org/10.4049/jimmunol.190.supp.114.15"},"language":"en","primary_location":{"id":"doi:10.4049/jimmunol.190.supp.114.15","doi":"https://doi.org/10.4049/jimmunol.190.supp.114.15","is_oa":false,"landing_page_url":"https://doi.org/10.4049/jimmunol.190.supp.114.15","pdf_url":null,"source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058398733","display_name":"Feng-Yen Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Feng-Yen Li","raw_affiliation_strings":["NIAID, NIH , Bethesda, MD","UCSF , San Francisco, CA","1UCSF, San Francisco, CA","2NIAID, NIH, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIAID, NIH , Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"UCSF , San Francisco, CA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"1UCSF, San Francisco, CA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"2NIAID, NIH, Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041090127","display_name":"Benjamin Chaigne-Delalande","orcid":"https://orcid.org/0000-0003-4423-5402","observed_orcids":["https://orcid.org/0000-0003-4423-5402"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin Chaigne-Delalande","raw_affiliation_strings":["NIAID, NIH , Bethesda, MD","2NIAID, NIH, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIAID, NIH , Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"2NIAID, NIH, Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086546785","display_name":"Geraldine M. O\u2019Connor","orcid":"https://orcid.org/0000-0002-7440-162X","observed_orcids":["https://orcid.org/0000-0002-7440-162X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Geraldine O\u2019Connor","raw_affiliation_strings":["NCI, NIH , Frederick, MD","3NCI, NIH, Frederick, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NCI, NIH , Frederick, MD","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"3NCI, NIH, Frederick, MD","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020081860","display_name":"Marshall J. Lukacs","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marshall Lukacs","raw_affiliation_strings":["NIAID, NIH , Bethesda, MD","2NIAID, NIH, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIAID, NIH , Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"2NIAID, NIH, Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088733725","display_name":"Lixin Zheng","orcid":"https://orcid.org/0000-0002-8838-8665","observed_orcids":["https://orcid.org/0000-0002-8838-8665"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lixin Zheng","raw_affiliation_strings":["NIAID, NIH , Bethesda, MD","2NIAID, NIH, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIAID, NIH , Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"2NIAID, NIH, Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043311871","display_name":"Amber N. Shatzer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amber Shatzer","raw_affiliation_strings":["NIAID, NIH , Bethesda, MD","2NIAID, NIH, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIAID, NIH , Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"2NIAID, NIH, Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108524254","display_name":"Helen F Matthews","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Helen Matthews","raw_affiliation_strings":["NIAID, NIH , Bethesda, MD","2NIAID, NIH, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIAID, NIH , Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"2NIAID, NIH, Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014247790","display_name":"Helen C. Su","orcid":"https://orcid.org/0000-0002-5582-9110","observed_orcids":["https://orcid.org/0000-0002-5582-9110"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Helen Su","raw_affiliation_strings":["NIAID, NIH , Bethesda, MD","2NIAID, NIH, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIAID, NIH , Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"2NIAID, NIH, Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024634769","display_name":"Jeffrey I. Cohen","orcid":"https://orcid.org/0000-0003-0238-7176","observed_orcids":["https://orcid.org/0000-0003-0238-7176"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey Cohen","raw_affiliation_strings":["NIAID, NIH , Bethesda, MD","2NIAID, NIH, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIAID, NIH , Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"2NIAID, NIH, Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005206087","display_name":"G\u00fclb\u00fb Uzel","orcid":"https://orcid.org/0000-0002-3942-1086","observed_orcids":["https://orcid.org/0000-0002-3942-1086","https://orcid.org/0009-0003-0700-694X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gulbu Uzel","raw_affiliation_strings":["NIAID, NIH , Bethesda, MD","2NIAID, NIH, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIAID, NIH , Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"2NIAID, NIH, Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071545468","display_name":"Michael J. Lenardo","orcid":"https://orcid.org/0000-0003-1584-468X","observed_orcids":["https://orcid.org/0000-0003-1584-468X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Lenardo","raw_affiliation_strings":["NIAID, NIH , Bethesda, MD","2NIAID, NIH, Bethesda, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIAID, NIH , Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"2NIAID, NIH, Bethesda, MD","institution_ids":["https://openalex.org/I1299303238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"190","issue":"Supplement_1","first_page":"114.15","last_page":"114.15"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.4702000021934509,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.4702000021934509,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.21330000460147858,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.10119999945163727,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypomagnesemia","display_name":"hypomagnesemia","score":0.6759999990463257},{"id":"https://openalex.org/keywords/magt1","display_name":"MAGT1","score":0.7670000195503235},{"id":"https://openalex.org/keywords/intracellular-free-magnesium","display_name":"intracellular free magnesium","score":0.9330000281333923},{"id":"https://openalex.org/keywords/nkg2d","display_name":"NKG2D","score":0.9290000200271606},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.8939999938011169},{"id":"https://openalex.org/keywords/cytotoxic-t-lymphocytes","display_name":"cytotoxic T lymphocytes","score":0.9959999918937683},{"id":"https://openalex.org/keywords/epstein-barr-virus-infection","display_name":"Epstein-Barr virus infection","score":0.824999988079071},{"id":"https://openalex.org/keywords/ebv-associated-lymphoma","display_name":"EBV-associated lymphoma","score":0.9200000166893005},{"id":"https://openalex.org/keywords/primary-immunodeficiency","display_name":"primary immunodeficiency","score":0.8519999980926514},{"id":"https://openalex.org/keywords/magnesium-supplementation","display_name":"magnesium supplementation","score":0.8370000123977661},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.7879999876022339}],"concepts":[{"id":"https://openalex.org/C2778867473","wikidata":"https://www.wikidata.org/wiki/Q17544382","display_name":"NKG2D","level":4,"score":0.6369035243988037},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6174259185791016},{"id":"https://openalex.org/C2781375147","wikidata":"https://www.wikidata.org/wiki/Q6900","display_name":"Epstein\u2013Barr virus","level":3,"score":0.6075671911239624},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6050668358802795},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5992646217346191},{"id":"https://openalex.org/C2777607303","wikidata":"https://www.wikidata.org/wiki/Q641307","display_name":"Immunodeficiency","level":3,"score":0.5364988446235657},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.5283886790275574},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.5224529504776001},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.4445400536060333},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4230494797229767},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4225327968597412},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35283738374710083},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.30167919397354126},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.1432671844959259},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.100457102060318}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4049/jimmunol.190.supp.114.15","doi":"https://doi.org/10.4049/jimmunol.190.supp.114.15","is_oa":false,"landing_page_url":"https://doi.org/10.4049/jimmunol.190.supp.114.15","pdf_url":null,"source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2024618208","https://openalex.org/W2052090039","https://openalex.org/W2037852126","https://openalex.org/W2063616047","https://openalex.org/W3105563442","https://openalex.org/W3030323428","https://openalex.org/W2990071267","https://openalex.org/W2948403965","https://openalex.org/W4308903521","https://openalex.org/W7116784291"],"abstract_inverted_index":{"Abstract":[0],"Epstein-Barr":[1],"virus":[2],"(EBV)":[3],"is":[4,38,51,67],"a":[5,20,68,97,188],"B":[6],"cell-tropic":[7],"gammaherpesvirus":[8],"present":[9],"in":[10,13,42,76,153,156,167,182],"latent":[11],"form":[12],"approximately":[14],"90%":[15],"of":[16,22,34,112,119,127,178,193],"people":[17],"worldwide.":[18],"However,":[19],"subset":[21],"immunocompromised":[23],"hosts":[24],"develop":[25],"malignancy":[26],"from":[27],"uncontrolled":[28],"EBV":[29,61,82,196],"infection.":[30],"While":[31],"the":[32,47,116,125,173],"etiology":[33],"such":[35],"immunodeficiency":[36,57,71],"states":[37],"sometimes":[39],"apparent,":[40],"as":[41],"HIV":[43],"and":[44,63,84,123,133,155,202],"post-transplant":[45],"immunosuppression,":[46],"underlying":[48],"immune":[49,191],"deficiency":[50],"other":[52],"cases":[53],"remains":[54],"unknown.":[55],"X-linked":[56],"with":[58],"Mg2+":[59,102,122,160,181],"defect,":[60],"infection,":[62],"neoplasia":[64],"(XMEN)":[65],"disease":[66],"novel":[69,189],"primary":[70],"characterized":[72],"by":[73,158],"deleterious":[74],"mutations":[75],"magnesium":[77],"transporter":[78],"1":[79],"(MAGT1),":[80],"chronic":[81],"infection":[83],"increased":[85],"susceptibility":[86],"for":[87,101,205],"EBV-associated":[88],"lymphomas.":[89],"We":[90],"had":[91],"previously":[92],"demonstrated":[93],"that":[94,110,198],"MAGT1":[95,113],"mediates":[96],"second":[98],"messenger":[99],"role":[100],"during":[103],"T":[104,135],"cell":[105,144],"activation.":[106],"Here,":[107],"we":[108],"show":[109],"loss":[111],"also":[114,186],"decreases":[115],"basal":[117,179],"level":[118],"intracellular":[120],"free":[121,180],"abolishes":[124],"expression":[126],"NKG2D":[128],"on":[129],"natural":[130],"killer":[131],"cells":[132,166,184],"cytotoxic":[134],"lymphocytes,":[136],"leading":[137,162],"to":[138,163],"impaired":[139],"cytotoxicity":[140],"against":[141,195],"EBV-transformed":[142],"lymphoblastoid":[143],"lines.":[145],"Interestingly,":[146],"both":[147],"these":[148],"defects":[149],"can":[150],"be":[151],"restored":[152],"vitro":[154],"vivo":[157],"exogenous":[159],"supplementation,":[161],"decreased":[164],"EBV-infected":[165],"vivo.":[168],"This":[169],"not":[170],"only":[171],"revealed":[172],"first":[174],"specific":[175],"molecular":[176],"function":[177],"eukaryotic":[183],"but":[185],"identified":[187],"Mg2+-dependent":[190],"arm":[192],"defense":[194],"lymphomagenesis":[197],"has":[199],"profound":[200],"diagnostic":[201],"therapeutic":[203],"implications":[204],"XMEN":[206],"disease.":[207]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":2}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2023-01-06T00:00:00"}