{"id":"https://openalex.org/W4313063054","doi":"https://doi.org/10.1007/978-981-19-5343-9_48","title":"Preclinical Toxicity Studies","display_name":"Preclinical Toxicity Studies","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4313063054","doi":"https://doi.org/10.1007/978-981-19-5343-9_48"},"language":"en","primary_location":{"id":"doi:10.1007/978-981-19-5343-9_48","doi":"https://doi.org/10.1007/978-981-19-5343-9_48","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-981-19-5343-9_48","pdf_url":null,"source":{"id":"https://openalex.org/S4363606347","display_name":"Introduction to Basics of Pharmacology and Toxicology","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Introduction to Basics of Pharmacology and Toxicology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4313065156","display_name":"Introduction to Basics of Pharmacology and Toxicology"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031569308","display_name":"Mageshwaran Lakshmanan","orcid":"https://orcid.org/0000-0002-7435-4966","observed_orcids":["https://orcid.org/0000-0002-7435-4966"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Mageshwaran Lakshmanan","raw_affiliation_strings":["Department of Pharmacology, Thanjavur Medical College, Thanjavur, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Thanjavur Medical College, Thanjavur, Tamil Nadu, India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5031569308"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":8.9516,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.98196393,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"625","last_page":"648"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12281","display_name":"Animal testing and alternatives","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12281","display_name":"Animal testing and alternatives","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13165","display_name":"Agricultural safety and regulations","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-toxicity","display_name":"acute toxicity","score":0.9419999718666077},{"id":"https://openalex.org/keywords/subacute-toxicity","display_name":"subacute toxicity","score":0.9390000104904175},{"id":"https://openalex.org/keywords/subchronic-toxicity","display_name":"subchronic toxicity","score":0.9829999804496765},{"id":"https://openalex.org/keywords/chronic-toxicity","display_name":"chronic toxicity","score":1.0},{"id":"https://openalex.org/keywords/repeated-dose-toxicity","display_name":"repeated-dose toxicity","score":0.8619999885559082},{"id":"https://openalex.org/keywords/single-dose-toxicity","display_name":"single-dose toxicity","score":0.906000018119812},{"id":"https://openalex.org/keywords/systemic-toxicity","display_name":"systemic toxicity","score":0.8389999866485596},{"id":"https://openalex.org/keywords/local-toxicity","display_name":"local toxicity","score":0.8949999809265137},{"id":"https://openalex.org/keywords/skin-toxicity","display_name":"skin toxicity","score":0.9869999885559082},{"id":"https://openalex.org/keywords/ocular-toxicity","display_name":"ocular toxicity","score":1.0},{"id":"https://openalex.org/keywords/reproductive-toxicity","display_name":"reproductive toxicity","score":0.9929999709129333},{"id":"https://openalex.org/keywords/animal-selection","display_name":"animal selection","score":0.8809999823570251},{"id":"https://openalex.org/keywords/dose-selection","display_name":"dose selection","score":0.9319999814033508},{"id":"https://openalex.org/keywords/study-duration","display_name":"study duration","score":0.7070000171661377}],"concepts":[{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.9439984560012817},{"id":"https://openalex.org/C53164099","wikidata":"https://www.wikidata.org/wiki/Q5114007","display_name":"Chronic toxicity","level":3,"score":0.7918776273727417},{"id":"https://openalex.org/C116263406","wikidata":"https://www.wikidata.org/wiki/Q3299024","display_name":"Acute toxicity","level":3,"score":0.7375613451004028},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5770541429519653},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5632688999176025},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14691898226737976}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-981-19-5343-9_48","doi":"https://doi.org/10.1007/978-981-19-5343-9_48","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-981-19-5343-9_48","pdf_url":null,"source":{"id":"https://openalex.org/S4363606347","display_name":"Introduction to Basics of Pharmacology and Toxicology","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Introduction to Basics of Pharmacology and Toxicology","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1504787233","https://openalex.org/W1511677874","https://openalex.org/W1538578591","https://openalex.org/W2029616918","https://openalex.org/W2042464457","https://openalex.org/W2479998885","https://openalex.org/W2500504132","https://openalex.org/W2571392343","https://openalex.org/W2970501782","https://openalex.org/W3111232738","https://openalex.org/W3151691775","https://openalex.org/W4237968504","https://openalex.org/W6632532917"],"related_works":["https://openalex.org/W3022226374","https://openalex.org/W2326837431","https://openalex.org/W4253992144","https://openalex.org/W3212804130","https://openalex.org/W1710512308","https://openalex.org/W4246661839","https://openalex.org/W4244458303","https://openalex.org/W4251804857","https://openalex.org/W4210783042","https://openalex.org/W4377427390"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2023-01-06T00:00:00"}