{"id":"https://openalex.org/W4311995273","doi":"https://doi.org/10.3390/genes13122321","title":"Transcriptomic Profiling Unravels Novel Deregulated Gene Signatures Associated with Acute Myocardial Infarction: A Bioinformatics Approach","display_name":"Transcriptomic Profiling Unravels Novel Deregulated Gene Signatures Associated with Acute Myocardial Infarction: A Bioinformatics Approach","publication_year":2022,"publication_date":"2022-12-09","ids":{"openalex":"https://openalex.org/W4311995273","doi":"https://doi.org/10.3390/genes13122321","pmid":"https://pubmed.ncbi.nlm.nih.gov/36553589","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9777571"},"language":"en","primary_location":{"id":"doi:10.3390/genes13122321","doi":"https://doi.org/10.3390/genes13122321","is_oa":true,"landing_page_url":"https://doi.org/10.3390/genes13122321","pdf_url":"https://www.mdpi.com/2073-4425/13/12/2321/pdf?version=1670580964","source":{"id":"https://openalex.org/S194631498","display_name":"Genes","issn_l":"2073-4425","issn":["2073-4425"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2073-4425/13/12/2321/pdf?version=1670580964","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074269903","display_name":"Sanjay Kumar","orcid":"https://orcid.org/0000-0001-6296-0291","observed_orcids":["https://orcid.org/0000-0001-6296-0291"]},"institutions":[{"id":"https://openalex.org/I74885063","display_name":"Sharda University","ror":"https://ror.org/03b6ffh07","country_code":"IN","type":"education","lineage":["https://openalex.org/I74885063"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sanjay Kumar","raw_affiliation_strings":["Department of Life Science, Sharda School of Basic Sciences and Research, Sharda University, Knowledge Park-III, Greater Noida 201310, India"],"raw_orcid":"https://orcid.org/0000-0001-6296-0291","affiliations":[{"raw_affiliation_string":"Department of Life Science, Sharda School of Basic Sciences and Research, Sharda University, Knowledge Park-III, Greater Noida 201310, India","institution_ids":["https://openalex.org/I74885063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051224639","display_name":"Chun-Ming Shih","orcid":"https://orcid.org/0000-0001-8088-6785","observed_orcids":["https://orcid.org/0000-0001-8088-6785"]},"institutions":[{"id":"https://openalex.org/I2802331550","display_name":"Taipei Medical University Hospital","ror":"https://ror.org/03k0md330","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802331550"]},{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chun-Ming Shih","raw_affiliation_strings":["Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 111031, Taiwan","Division of Cardiology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 111031, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 111031, Taiwan","institution_ids":["https://openalex.org/I47519274"]},{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 111031, Taiwan","institution_ids":["https://openalex.org/I2802331550","https://openalex.org/I47519274"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lung-Wen Tsai","orcid":"https://orcid.org/0000-0002-3541-5834","observed_orcids":["https://orcid.org/0000-0002-3541-5834"]},"institutions":[{"id":"https://openalex.org/I2802331550","display_name":"Taipei Medical University Hospital","ror":"https://ror.org/03k0md330","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802331550"]},{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Lung-Wen Tsai","raw_affiliation_strings":["Department of Information Technology Office, Taipei Medical University Hospital, Taipei 11031, Taiwan","Department of Medicine Research, Taipei Medical University Hospital, Taipei 111031, Taiwan","Graduate Institute of Data Science, College of Management, Taipei Medical University, Taipei 11031, Taiwan"],"raw_orcid":"https://orcid.org/0000-0002-3541-5834","affiliations":[{"raw_affiliation_string":"Department of Information Technology Office, Taipei Medical University Hospital, Taipei 11031, Taiwan","institution_ids":["https://openalex.org/I2802331550"]},{"raw_affiliation_string":"Department of Medicine Research, Taipei Medical University Hospital, Taipei 111031, Taiwan","institution_ids":["https://openalex.org/I2802331550"]},{"raw_affiliation_string":"Graduate Institute of Data Science, College of Management, Taipei Medical University, Taipei 11031, Taiwan","institution_ids":["https://openalex.org/I47519274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055811979","display_name":"Rajni Dubey","orcid":"https://orcid.org/0000-0002-0506-7744","observed_orcids":["https://orcid.org/0000-0002-0506-7744"]},"institutions":[{"id":"https://openalex.org/I2802331550","display_name":"Taipei Medical University Hospital","ror":"https://ror.org/03k0md330","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802331550"]},{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Rajni Dubey","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 111031, Taiwan"],"raw_orcid":"https://orcid.org/0000-0002-0506-7744","affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 111031, Taiwan","institution_ids":["https://openalex.org/I2802331550","https://openalex.org/I47519274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106081273","display_name":"Deepika Gupta","orcid":"https://orcid.org/0009-0005-6397-3090","observed_orcids":["https://orcid.org/0009-0005-6397-3090"]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Deepika Gupta","raw_affiliation_strings":["Department of Neurology, All India Institute of Medical Sciences, New Delhi 110029, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, All India Institute of Medical Sciences, New Delhi 110029, India","institution_ids":["https://openalex.org/I63739035"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046521217","display_name":"Tanmoy Chakraborty","orcid":"https://orcid.org/0000-0002-0210-0369","observed_orcids":["https://orcid.org/0000-0002-0210-0369"]},"institutions":[{"id":"https://openalex.org/I74885063","display_name":"Sharda University","ror":"https://ror.org/03b6ffh07","country_code":"IN","type":"education","lineage":["https://openalex.org/I74885063"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Tanmoy Chakraborty","raw_affiliation_strings":["Department of Chemistry and Biochemistry, Sharda School of Basic Sciences and Research, Sharda University, Knowledge Park-III, Greater Noida 201310, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Sharda School of Basic Sciences and Research, Sharda University, Knowledge Park-III, Greater Noida 201310, India","institution_ids":["https://openalex.org/I74885063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103361426","display_name":"Naveen Sharma","orcid":"https://orcid.org/0000-0003-1936-4042","observed_orcids":["https://orcid.org/0000-0003-1936-4042"]},"institutions":[{"id":"https://openalex.org/I37048141","display_name":"Indian Council of Medical Research","ror":"https://ror.org/0492wrx28","country_code":"IN","type":"government","lineage":["https://openalex.org/I37048141"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Naveen Sharma","raw_affiliation_strings":["Biomedical Informatics Division, Indian Council of Medical Research, New Delhi 110029, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Informatics Division, Indian Council of Medical Research, New Delhi 110029, India","institution_ids":["https://openalex.org/I37048141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115593597","display_name":"Abhishek Singh","orcid":"https://orcid.org/0000-0002-7952-539X","observed_orcids":["https://orcid.org/0000-0002-7952-539X","https://orcid.org/0009-0004-3026-7459","https://orcid.org/0000-0002-0744-0821"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Abhishek Singh","raw_affiliation_strings":["Department of Cardiology, Infinity Care Hospital, Varanasi 221002, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Infinity Care Hospital, Varanasi 221002, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048543070","display_name":"Vishnu Swarup","orcid":"https://orcid.org/0000-0003-0759-7818","observed_orcids":["https://orcid.org/0000-0003-0759-7818"]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Vishnu Swarup","raw_affiliation_strings":["Department of Neurology, All India Institute of Medical Sciences, New Delhi 110029, India"],"raw_orcid":"https://orcid.org/0000-0003-0759-7818","affiliations":[{"raw_affiliation_string":"Department of Neurology, All India Institute of Medical Sciences, New Delhi 110029, India","institution_ids":["https://openalex.org/I63739035"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071080377","display_name":"Himanshu Narayan Singh","orcid":"https://orcid.org/0000-0003-4111-5165","observed_orcids":["https://orcid.org/0000-0003-4111-5165"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Himanshu Singh","raw_affiliation_strings":["Department of System Biology, University of Columbia Irving Medical Center, New York, NY 10032, USA"],"raw_orcid":"https://orcid.org/0000-0003-4111-5165","affiliations":[{"raw_affiliation_string":"Department of System Biology, University of Columbia Irving Medical Center, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5048543070","https://openalex.org/A5071080377"],"corresponding_institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I63739035","https://openalex.org/I78577930"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2513},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2513},"fwci":0.2206,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.38943159,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"13","issue":"12","first_page":"2321","last_page":"2321"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.6987000107765198,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.6987000107765198,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.06849999725818634,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.06650000065565109,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-myocardial-infarction","display_name":"acute myocardial infarction","score":1.0},{"id":"https://openalex.org/keywords/gene-expression-signatures","display_name":"gene expression signatures","score":0.8370000123977661},{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.859000027179718},{"id":"https://openalex.org/keywords/cardioprotection","display_name":"cardioprotection","score":0.9129999876022339},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7239999771118164},{"id":"https://openalex.org/keywords/bmp6","display_name":"BMP6","score":0.9959999918937683},{"id":"https://openalex.org/keywords/gpx3","display_name":"glutathione peroxidase 3","score":0.9900000095367432},{"id":"https://openalex.org/keywords/stat1","display_name":"STAT1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cardiomyocyte-injury","display_name":"cardiomyocyte injury","score":0.7379999756813049},{"id":"https://openalex.org/keywords/gene-co-expression-modules","display_name":"gene co-expression modules","score":0.7120000123977661}],"concepts":[{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.7463206052780151},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.6959199905395508},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5278682112693787},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.5256580114364624},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4954138994216919},{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.4709796905517578},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.46794572472572327},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3895837366580963},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34483808279037476},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.30230239033699036},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2433030605316162},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.24302977323532104},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18368670344352722},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3390/genes13122321","doi":"https://doi.org/10.3390/genes13122321","is_oa":true,"landing_page_url":"https://doi.org/10.3390/genes13122321","pdf_url":"https://www.mdpi.com/2073-4425/13/12/2321/pdf?version=1670580964","source":{"id":"https://openalex.org/S194631498","display_name":"Genes","issn_l":"2073-4425","issn":["2073-4425"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9777571","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9777571","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes (Basel)","raw_type":"Text"},{"id":"pmid:36553589","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36553589","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:747f056fbb5946b69218022ea2598801","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/747f056fbb5946b69218022ea2598801","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Genes, Vol 13, Iss 2321, p 2321 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/genes13122321","doi":"https://doi.org/10.3390/genes13122321","is_oa":true,"landing_page_url":"https://doi.org/10.3390/genes13122321","pdf_url":"https://www.mdpi.com/2073-4425/13/12/2321/pdf?version=1670580964","source":{"id":"https://openalex.org/S194631498","display_name":"Genes","issn_l":"2073-4425","issn":["2073-4425"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320324337","display_name":"All-India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71"},{"id":"https://openalex.org/F4320329488","display_name":"Sharda University","ror":"https://ror.org/03b6ffh07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4311995273.pdf","grobid_xml":"https://content.openalex.org/works/W4311995273.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W145046761","https://openalex.org/W1197081707","https://openalex.org/W1549749341","https://openalex.org/W1554797744","https://openalex.org/W1966327575","https://openalex.org/W1973927689","https://openalex.org/W2018146487","https://openalex.org/W2023766870","https://openalex.org/W2031536729","https://openalex.org/W2032578967","https://openalex.org/W2034893553","https://openalex.org/W2035604680","https://openalex.org/W2037627674","https://openalex.org/W2043774853","https://openalex.org/W2049917711","https://openalex.org/W2058584041","https://openalex.org/W2070050178","https://openalex.org/W2084218441","https://openalex.org/W2092013338","https://openalex.org/W2099925531","https://openalex.org/W2103439384","https://openalex.org/W2104857427","https://openalex.org/W2126214253","https://openalex.org/W2129810444","https://openalex.org/W2133084720","https://openalex.org/W2133203435","https://openalex.org/W2143244467","https://openalex.org/W2148706434","https://openalex.org/W2149301000","https://openalex.org/W2159506419","https://openalex.org/W2181254345","https://openalex.org/W2300087591","https://openalex.org/W2345356016","https://openalex.org/W2385199316","https://openalex.org/W2435309143","https://openalex.org/W2508444883","https://openalex.org/W2510202369","https://openalex.org/W2561862824","https://openalex.org/W2604752830","https://openalex.org/W2734404588","https://openalex.org/W2803472374","https://openalex.org/W2806521060","https://openalex.org/W2810200347","https://openalex.org/W2899139820","https://openalex.org/W2918014537","https://openalex.org/W2949705082","https://openalex.org/W2953352915","https://openalex.org/W2986956954","https://openalex.org/W2989814060","https://openalex.org/W3020782024","https://openalex.org/W3036731955","https://openalex.org/W3152802437","https://openalex.org/W4214505317","https://openalex.org/W4220911578"],"related_works":["https://openalex.org/W2674744780","https://openalex.org/W3197567479","https://openalex.org/W2918014537","https://openalex.org/W4200264353","https://openalex.org/W2765588508","https://openalex.org/W2560549978","https://openalex.org/W4206683673","https://openalex.org/W3152802437","https://openalex.org/W2964467456","https://openalex.org/W2048203142"],"abstract_inverted_index":{"Acute":[0],"myocardial":[1,49],"infarction":[2],"(AMI)":[3],"is":[4,16,166],"a":[5,179],"severe":[6,187],"disease":[7],"with":[8,145],"elevated":[9],"morbidity":[10],"and":[11,70,98,120,125,140,163,175],"mortality":[12],"rate":[13],"worldwide.":[14],"This":[15],"attributed":[17],"to":[18,38,43,78,107,168],"great":[19],"losses":[20],"of":[21,28,114,118,161,184,201],"cardiomyocytes,":[22],"which":[23,115,165,189],"can":[24],"trigger":[25],"the":[26,40,54,116,132,159,182,199],"alteration":[27],"gene":[29,61,81,100],"expression":[30,62],"patterns.":[31],"Although":[32],"several":[33],"attempts":[34],"have":[35],"been":[36],"made":[37],"assess":[39],"AMI":[41,65,170],"biomarkers,":[42],"date":[44],"their":[45,71],"role":[46,181],"in":[47,87,193],"rescuing":[48],"injury":[50],"remains":[51],"unclear.":[52],"Therefore,":[53],"current":[55],"study":[56],"investigated":[57],"three":[58],"independent":[59],"microarray-based":[60],"datasets":[63],"from":[64,186],"patients":[66],"(n":[67,75],"=":[68,76],"85)":[69],"age-sex-matched":[72],"healthy":[73],"controls":[74],"70),":[77],"identify":[79,108],"novel":[80],"signatures":[82],"that":[83,131],"might":[84,177],"be":[85,143,191],"involved":[86],"cardioprotection.":[88],"The":[89,156],"differentially":[90],"expressed":[91],"genes":[92,122,134,174],"(DEGs)":[93],"were":[94,123],"analyzed":[95],"using":[96],"'GEO2R',":[97],"weighted":[99],"correlation":[101],"network":[102],"analysis":[103],"(WGCNA)":[104],"was":[105],"performed":[106],"biomarkers/modules.":[109],"We":[110],"found":[111,130],"91":[112],"DEGs,":[113],"number":[117],"upregulated":[119],"downregulated":[121],"22":[124],"5,":[126],"respectively.":[127],"Specifically,":[128],"we":[129],"deregulated":[133],"such":[135],"as":[136],"ADOR-A3,":[137],"BMP6,":[138],"VPS8,":[139],"GPx3,":[141],"may":[142],"associated":[144],"AMI.":[146,202],"WGCNA":[147],"revealed":[148],"four":[149],"highly":[150],"preserved":[151],"modules":[152],"among":[153],"all":[154],"datasets.":[155],"'Enrichr'":[157],"unveiled":[158],"presence":[160],"miR-660":[162],"STAT1,":[164],"known":[167],"affect":[169],"severity.":[171],"Conclusively,":[172],"these":[173],"miRNA":[176],"play":[178],"crucial":[180],"rescue":[183],"cardiomyocytes":[185],"damage,":[188],"could":[190],"helpful":[192],"developing":[194],"appropriate":[195],"therapeutic":[196],"strategies":[197],"for":[198],"management":[200]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2023-01-03T00:00:00"}