{"id":"https://openalex.org/W4311832142","doi":"https://doi.org/10.1186/s12985-022-01951-7","title":"Mutations in SARS-CoV-2 structural proteins: a global analysis","display_name":"Mutations in SARS-CoV-2 structural proteins: a global analysis","publication_year":2022,"publication_date":"2022-12-18","ids":{"openalex":"https://openalex.org/W4311832142","doi":"https://doi.org/10.1186/s12985-022-01951-7","pmid":"https://pubmed.ncbi.nlm.nih.gov/36528612","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9759450"},"language":"en","primary_location":{"id":"doi:10.1186/s12985-022-01951-7","doi":"https://doi.org/10.1186/s12985-022-01951-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12985-022-01951-7","pdf_url":"https://virologyj.biomedcentral.com/counter/pdf/10.1186/s12985-022-01951-7","source":{"id":"https://openalex.org/S115714813","display_name":"Virology Journal","issn_l":"1743-422X","issn":["1743-422X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://virologyj.biomedcentral.com/counter/pdf/10.1186/s12985-022-01951-7","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051487408","display_name":"Mohammad Abavisani","orcid":"https://orcid.org/0000-0002-1416-2794","observed_orcids":["https://orcid.org/0000-0002-1416-2794","https://orcid.org/0000-0002-7262-2795"]},"institutions":[{"id":"https://openalex.org/I165560825","display_name":"Mashhad University of Medical Sciences","ror":"https://ror.org/04sfka033","country_code":"IR","type":"education","lineage":["https://openalex.org/I165560825"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Abavisani","raw_affiliation_strings":["Department of Microbiology and Virology, School of Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran","Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Virology, School of Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran","institution_ids":["https://openalex.org/I165560825"]},{"raw_affiliation_string":"Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran","institution_ids":["https://openalex.org/I165560825"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073314328","display_name":"Karim Rahimian","orcid":"https://orcid.org/0000-0002-9612-2111","observed_orcids":["https://orcid.org/0000-0002-9612-2111"]},"institutions":[{"id":"https://openalex.org/I23946033","display_name":"University of Tehran","ror":"https://ror.org/05vf56z40","country_code":"IR","type":"education","lineage":["https://openalex.org/I23946033"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Karim Rahimian","raw_affiliation_strings":["Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, Iran","institution_ids":["https://openalex.org/I23946033"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077588659","display_name":"Bahar Mahdavi","orcid":"https://orcid.org/0000-0002-4565-6615","observed_orcids":["https://orcid.org/0000-0002-4565-6615"]},"institutions":[{"id":"https://openalex.org/I202419968","display_name":"Royan Institute","ror":"https://ror.org/02exhb815","country_code":"IR","type":"nonprofit","lineage":["https://openalex.org/I202419968"]},{"id":"https://openalex.org/I2802694670","display_name":"Academic Center for Education, Culture and Research","ror":"https://ror.org/0126z4b94","country_code":"IR","type":"nonprofit","lineage":["https://openalex.org/I2802694670"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Bahar Mahdavi","raw_affiliation_strings":["Department of Molecular Biotechnology, Cell Science Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biotechnology, Cell Science Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran","institution_ids":["https://openalex.org/I202419968","https://openalex.org/I2802694670"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066111459","display_name":"Samaneh Tokhanbigli","orcid":"https://orcid.org/0000-0001-5619-6637","observed_orcids":["https://orcid.org/0000-0001-5619-6637","https://orcid.org/0000-0001-8927-8313"]},"institutions":[{"id":"https://openalex.org/I110525433","display_name":"Islamic Azad University, Tehran","ror":"https://ror.org/01kzn7k21","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433"]},{"id":"https://openalex.org/I4210152512","display_name":"Islamic Azad University Pharmaceutical Sciences Branch","ror":"https://ror.org/04sssnv16","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I4210152512"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Samaneh Tokhanbigli","raw_affiliation_strings":["Department of Molecular and Cellular Sciences, Faculty of Advanced Sciences and Technology, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Sciences, Faculty of Advanced Sciences and Technology, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran","institution_ids":["https://openalex.org/I110525433","https://openalex.org/I4210152512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007846185","display_name":"Mahsa Mollapour Sisakht","orcid":"https://orcid.org/0000-0003-0396-676X","observed_orcids":["https://orcid.org/0000-0003-0396-676X"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Mahsa Mollapour Siasakht","raw_affiliation_strings":["Department of Biochemistry, Erasmus University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands","Department of Biochemistry, Erasmus University Medical Center, Rotterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Erasmus University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Department of Biochemistry, Erasmus University Medical Center, Rotterdam, The Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055237943","display_name":"Amin Farhadi","orcid":"https://orcid.org/0000-0002-1224-7145","observed_orcids":["https://orcid.org/0000-0002-1224-7145"]},"institutions":[{"id":"https://openalex.org/I55547365","display_name":"Payame Noor University","ror":"https://ror.org/031699d98","country_code":"IR","type":"education","lineage":["https://openalex.org/I55547365"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Amin Farhadi","raw_affiliation_strings":["Department of Biology, Payame Noor University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Payame Noor University, Tehran, Iran","institution_ids":["https://openalex.org/I55547365"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037939178","display_name":"Mansoor Kodori","orcid":"https://orcid.org/0000-0002-9197-9335","observed_orcids":["https://orcid.org/0000-0002-9197-9335","https://orcid.org/0000-0002-4881-6434"]},"institutions":[{"id":"https://openalex.org/I4210121477","display_name":"Bam University of Medical Sciences","ror":"https://ror.org/02mm76478","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210121477"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mansoor Kodori","raw_affiliation_strings":["Non Communicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Non Communicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran","institution_ids":["https://openalex.org/I4210121477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038769031","display_name":"Mohammadamin Mahmanzar","orcid":"https://orcid.org/0000-0002-3793-6553","observed_orcids":["https://orcid.org/0000-0002-3793-6553"]},"institutions":[{"id":"https://openalex.org/I23946033","display_name":"University of Tehran","ror":"https://ror.org/05vf56z40","country_code":"IR","type":"education","lineage":["https://openalex.org/I23946033"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Mohammadamin Mahmanzar","raw_affiliation_strings":["Department of Bioinformatics, Kish International Campus University of Tehran, Kish, Iran. Mahmanzar.ma@ut.ac.ir","Department of Bioinformatics, Kish International Campus University of Tehran, Kish, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioinformatics, Kish International Campus University of Tehran, Kish, Iran. Mahmanzar.ma@ut.ac.ir","institution_ids":["https://openalex.org/I23946033"]},{"raw_affiliation_string":"Department of Bioinformatics, Kish International Campus University of Tehran, Kish, Iran","institution_ids":["https://openalex.org/I23946033"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081926728","display_name":"Zahra Meshkat","orcid":"https://orcid.org/0000-0002-4032-7599","observed_orcids":["https://orcid.org/0000-0002-4032-7599"]},"institutions":[{"id":"https://openalex.org/I165560825","display_name":"Mashhad University of Medical Sciences","ror":"https://ror.org/04sfka033","country_code":"IR","type":"education","lineage":["https://openalex.org/I165560825"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Zahra Meshkat","raw_affiliation_strings":["Department of Microbiology and Virology, School of Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. zmeshkat@gmail.com","Department of Microbiology and Virology, School of Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Virology, School of Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. zmeshkat@gmail.com","institution_ids":["https://openalex.org/I165560825"]},{"raw_affiliation_string":"Department of Microbiology and Virology, School of Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran","institution_ids":["https://openalex.org/I165560825"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5038769031","https://openalex.org/A5081926728"],"corresponding_institution_ids":["https://openalex.org/I165560825","https://openalex.org/I23946033"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":{"value":2890,"currency":"USD","value_usd":2890},"fwci":8.0547,"has_fulltext":true,"cited_by_count":70,"citation_normalized_percentile":{"value":0.98473658,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"19","issue":"1","first_page":"220","last_page":"220"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11495","display_name":"Animal Virus Infections Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/variants-of-concern","display_name":"variants of concern","score":0.8050000071525574},{"id":"https://openalex.org/keywords/spike-protein","display_name":"spike protein","score":0.9330000281333923},{"id":"https://openalex.org/keywords/envelope-protein","display_name":"envelope protein","score":0.8619999885559082},{"id":"https://openalex.org/keywords/membrane-proteins","display_name":"membrane proteins","score":0.984000027179718},{"id":"https://openalex.org/keywords/nucleocapsid-protein","display_name":"nucleocapsid protein","score":1.0},{"id":"https://openalex.org/keywords/d614g-mutation","display_name":"D614G mutation","score":0.9319999814033508},{"id":"https://openalex.org/keywords/e484k","display_name":"E484K","score":0.8330000042915344},{"id":"https://openalex.org/keywords/n501y","display_name":"N501Y","score":0.9950000047683716},{"id":"https://openalex.org/keywords/amino-acid-sequence-analysis","display_name":"amino acid sequence analysis","score":0.531000018119812},{"id":"https://openalex.org/keywords/viral-evolution","display_name":"viral evolution","score":0.35100001096725464},{"id":"https://openalex.org/keywords/drug-and-vaccine-development","display_name":"vaccine and drug development","score":0.6650000214576721}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7181656360626221},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.7067775726318359},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.648679792881012},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5541502833366394},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5341521501541138},{"id":"https://openalex.org/C2777648638","wikidata":"https://www.wikidata.org/wiki/Q57751738","display_name":"Coronavirus","level":5,"score":0.449310302734375},{"id":"https://openalex.org/C195491092","wikidata":"https://www.wikidata.org/wiki/Q2717121","display_name":"Silent mutation","level":5,"score":0.43373316526412964},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.41555047035217285},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.38879501819610596},{"id":"https://openalex.org/C75563809","wikidata":"https://www.wikidata.org/wiki/Q2656896","display_name":"Missense mutation","level":4,"score":0.12543898820877075},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11076369881629944},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0750439465045929},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019251","descriptor_name":"Nucleocapsid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064370","descriptor_name":"Spike Glycoprotein, Coronavirus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/s12985-022-01951-7","doi":"https://doi.org/10.1186/s12985-022-01951-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12985-022-01951-7","pdf_url":"https://virologyj.biomedcentral.com/counter/pdf/10.1186/s12985-022-01951-7","source":{"id":"https://openalex.org/S115714813","display_name":"Virology Journal","issn_l":"1743-422X","issn":["1743-422X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9759450","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9759450","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virol J","raw_type":"Text"},{"id":"pmid:36528612","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36528612","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology journal","raw_type":"Journal Article"},{"id":"pmh:oai:pure.eur.nl:openaire/bd3964d5-a676-4c28-bfbc-556cf7ed113e","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/bd3964d5-a676-4c28-bfbc-556cf7ed113e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Abavisani, M, Rahimian, K, Mahdavi, B, Tokhanbigli, S, Mollapour Siasakht, M, Farhadi, A, Kodori, M, Mahmanzar, M & Meshkat, Z 2022, 'Mutations in SARS-CoV-2 structural proteins : a global analysis', Virology Journal, vol. 19, no. 1, 220. https://doi.org/10.1186/s12985-022-01951-7","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:eur:oai:pure.eur.nl:publications/bd3964d5-a676-4c28-bfbc-556cf7ed113e","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/bd3964d5-a676-4c28-bfbc-556cf7ed113e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Virology Journal, 19(1):220. BioMed Central Ltd.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:bfbd35344ae646b0b7e310e6509d22a8","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/bfbd35344ae646b0b7e310e6509d22a8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Virology Journal, Vol 19, Iss 1, Pp 1-19 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12985-022-01951-7","doi":"https://doi.org/10.1186/s12985-022-01951-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12985-022-01951-7","pdf_url":"https://virologyj.biomedcentral.com/counter/pdf/10.1186/s12985-022-01951-7","source":{"id":"https://openalex.org/S115714813","display_name":"Virology Journal","issn_l":"1743-422X","issn":["1743-422X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4311832142.pdf","grobid_xml":"https://content.openalex.org/works/W4311832142.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W2075107227","https://openalex.org/W2131970968","https://openalex.org/W2587970647","https://openalex.org/W2605343262","https://openalex.org/W2993780472","https://openalex.org/W3003464757","https://openalex.org/W3004227146","https://openalex.org/W3016762840","https://openalex.org/W3022285953","https://openalex.org/W3032255042","https://openalex.org/W3034548712","https://openalex.org/W3038536401","https://openalex.org/W3039901154","https://openalex.org/W3043431476","https://openalex.org/W3067557104","https://openalex.org/W3082060340","https://openalex.org/W3085912969","https://openalex.org/W3087255465","https://openalex.org/W3088334807","https://openalex.org/W3095956988","https://openalex.org/W3098697637","https://openalex.org/W3106565768","https://openalex.org/W3108737416","https://openalex.org/W3117310101","https://openalex.org/W3125358417","https://openalex.org/W3125800928","https://openalex.org/W3127652512","https://openalex.org/W3131304542","https://openalex.org/W3133725402","https://openalex.org/W3133794453","https://openalex.org/W3134208712","https://openalex.org/W3135556657","https://openalex.org/W3136828643","https://openalex.org/W3156343712","https://openalex.org/W3159257193","https://openalex.org/W3159808717","https://openalex.org/W3163890774","https://openalex.org/W3174747632","https://openalex.org/W3190784961","https://openalex.org/W3197975486","https://openalex.org/W3198233589","https://openalex.org/W3206517538","https://openalex.org/W3208566544","https://openalex.org/W3211827836","https://openalex.org/W3213840138","https://openalex.org/W3217313168","https://openalex.org/W4200137031","https://openalex.org/W4200617836","https://openalex.org/W4205855819","https://openalex.org/W4210810377","https://openalex.org/W4213168878","https://openalex.org/W4213456376","https://openalex.org/W4220827792","https://openalex.org/W4223443440","https://openalex.org/W4287510152","https://openalex.org/W4292528167","https://openalex.org/W4306704015","https://openalex.org/W4310948045"],"related_works":["https://openalex.org/W4287578413","https://openalex.org/W4310948045","https://openalex.org/W4205804394","https://openalex.org/W4283383218","https://openalex.org/W4283460992","https://openalex.org/W3172306785","https://openalex.org/W3024346179","https://openalex.org/W3128371513","https://openalex.org/W3212845348","https://openalex.org/W4361213606"],"abstract_inverted_index":{"BACKGROUND:":[0],"Emergence":[1],"of":[2,7,18,36,43,61,75,134],"new":[3],"variants":[4,6],"mainly":[5],"concerns":[8],"(VOC)":[9],"is":[10],"caused":[11],"by":[12,80],"mutations":[13,32,76,121,153,192,222],"in":[14,131,154,173,193],"main":[15],"structural":[16,34,104,220],"proteins":[17,35,57,160],"severe":[19],"acute":[20],"respiratory":[21],"syndrome":[22],"coronavirus":[23,63],"2":[24],"(SARS-CoV-2).":[25],"Therefore,":[26],"we":[27],"aimed":[28],"to":[29,68,84,136,139,142,146],"investigate":[30],"the":[31,59,62,82,85,97,102,118,123,132,169,189,207,219],"among":[33,122],"SARS-CoV-2":[37],"globally.":[38,196],"METHODS:":[39],"We":[40],"analyzed":[41],"samples":[42],"amino-acid":[44],"sequences":[45,83],"(AASs)":[46],"for":[47],"envelope":[48],"(E),":[49],"membrane":[50],"(M),":[51],"nucleocapsid":[52],"(N),":[53],"and":[54,73,88,94,108,127,144,158,165,183,213,229],"spike":[55],"(S)":[56],"from":[58],"declaration":[60],"2019":[64],"(COVID-19)":[65],"as":[66,188,206],"pandemic":[67],"January":[69],"2022.":[70],"The":[71,114,150],"presence":[72],"location":[74],"were":[77,106,111,161,186],"then":[78],"investigated":[79],"aligning":[81],"reference":[86],"sequence":[87],"categorizing":[89],"them":[90],"based":[91],"on":[92],"frequency":[93],"continent.":[95],"Finally,":[96],"related":[98],"human":[99],"genes":[100,105],"with":[101],"viral":[103],"discovered,":[107],"their":[109],"interactions":[110],"reported.":[112],"RESULTS:":[113],"results":[115],"indicated":[116],"that":[117],"most":[119,151,170,190],"relative":[120],"E,":[124,155,212],"M,":[125,156,211],"N,":[126,157],"S":[128,159,194],"AASs":[129],"occurred":[130],"regions":[133],"7":[135],"14,":[137],"66":[138],"88,":[140],"164":[141],"205,":[143],"508":[145],"635":[147],"AAs,":[148],"respectively.":[149],"frequent":[152,171,191],"T9I,":[162],"I82T,":[163],"R203M/R203K,":[164],"D614G.":[166],"D614G":[167],"was":[168,204],"mutation":[172],"all":[174],"six":[175],"geographical":[176],"areas.":[177],"Following":[178],"D614G,":[179],"L18F,":[180],"A222V,":[181],"E484K,":[182],"N501Y,":[184],"respectively,":[185],"ranked":[187],"protein":[195,221],"Besides,":[197],"A-kinase":[198],"Anchoring":[199],"Protein":[200],"8":[201],"Like":[202],"(AKAP8L)":[203],"shown":[205],"linkage":[208],"unit":[209],"between":[210],"E":[214],"cluster":[215],"genes.":[216],"CONCLUSION:":[217],"Screening":[218],"can":[223],"help":[224],"scientists":[225],"introduce":[226],"better":[227],"drug":[228],"vaccine":[230],"development":[231],"strategies.":[232]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":24},{"year":2023,"cited_by_count":28}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-12-31T00:00:00"}
