{"id":"https://openalex.org/W4311020006","doi":"https://doi.org/10.3389/fmed.2022.1049697","title":"Editorial: Driving extracellular vesicles toward applications in precision medicine","display_name":"Editorial: Driving extracellular vesicles toward applications in precision medicine","publication_year":2022,"publication_date":"2022-11-22","ids":{"openalex":"https://openalex.org/W4311020006","doi":"https://doi.org/10.3389/fmed.2022.1049697","pmid":"https://pubmed.ncbi.nlm.nih.gov/36482912","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9723454"},"language":"en","primary_location":{"id":"doi:10.3389/fmed.2022.1049697","doi":"https://doi.org/10.3389/fmed.2022.1049697","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmed.2022.1049697","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmed.2022.1049697/pdf","source":{"id":"https://openalex.org/S2597052008","display_name":"Frontiers in Medicine","issn_l":"2296-858X","issn":["2296-858X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Medicine","raw_type":"journal-article"},"volume":null,"type":"editorial","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fmed.2022.1049697/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047182592","display_name":"Somchai Chutipongtanate","orcid":"https://orcid.org/0000-0001-6398-5626","observed_orcids":["https://orcid.org/0000-0001-6398-5626"]},"institutions":[{"id":"https://openalex.org/I25399158","display_name":"Mahidol University","ror":"https://ror.org/01znkr924","country_code":"TH","type":"education","lineage":["https://openalex.org/I25399158"]},{"id":"https://openalex.org/I4210140007","display_name":"Ramathibodi Hospital","ror":"https://ror.org/04884sy85","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I4210140007"]},{"id":"https://openalex.org/I4405276763","display_name":"Ramathibodi Chakri Naruebodindra Hospital","ror":"https://ror.org/007az5z58","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I4405276763"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["TH","US"],"is_corresponding":true,"raw_author_name":"Somchai Chutipongtanate","raw_affiliation_strings":["Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan, Thailand","Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand","Division of Epidemiology, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH, United States","Pediatric Translational Research Unit, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand","Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand","Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand","Division of Epidemiology, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, United States","Pediatric Translational Research Unit, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan, Thailand","institution_ids":["https://openalex.org/I25399158","https://openalex.org/I4210140007","https://openalex.org/I4405276763"]},{"raw_affiliation_string":"Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I25399158","https://openalex.org/I4210140007"]},{"raw_affiliation_string":"Division of Epidemiology, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH, United States","institution_ids":["https://openalex.org/I63135867"]},{"raw_affiliation_string":"Pediatric Translational Research Unit, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I25399158","https://openalex.org/I4210140007"]},{"raw_affiliation_string":"Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand","institution_ids":["https://openalex.org/I25399158","https://openalex.org/I4210140007","https://openalex.org/I4405276763"]},{"raw_affiliation_string":"Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand","institution_ids":["https://openalex.org/I25399158","https://openalex.org/I4210140007"]},{"raw_affiliation_string":"Division of Epidemiology, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, United States","institution_ids":["https://openalex.org/I63135867"]},{"raw_affiliation_string":"Pediatric Translational Research Unit, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand","institution_ids":["https://openalex.org/I25399158","https://openalex.org/I4210140007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039568106","display_name":"Kovit Pattanapanyasat","orcid":"https://orcid.org/0000-0003-1037-6610","observed_orcids":["https://orcid.org/0000-0003-1037-6610"]},"institutions":[{"id":"https://openalex.org/I1332387789","display_name":"Siriraj Hospital","ror":"https://ror.org/0331zs648","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I1332387789"]},{"id":"https://openalex.org/I25399158","display_name":"Mahidol University","ror":"https://ror.org/01znkr924","country_code":"TH","type":"education","lineage":["https://openalex.org/I25399158"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Kovit Pattanapanyasat","raw_affiliation_strings":["Center of Excellence for Microparticle and Exosome in Diseases, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand","Center of Excellence for Microparticle and Exosome in Diseases, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Excellence for Microparticle and Exosome in Diseases, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I1332387789","https://openalex.org/I25399158"]},{"raw_affiliation_string":"Center of Excellence for Microparticle and Exosome in Diseases, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand","institution_ids":["https://openalex.org/I1332387789","https://openalex.org/I25399158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090178417","display_name":"Jarek Meller","orcid":"https://orcid.org/0000-0002-1162-8253","observed_orcids":["https://orcid.org/0000-0002-1162-8253"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jarek Meller","raw_affiliation_strings":["Department of Biomedical Informatics, University of Cincinnati College of Medicine, Cincinnati, OH, United States","Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States","Division of Biostatistics and Bioinformatics, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH, United States","Department of Biomedical Informatics, University of Cincinnati College of Medicine, United States","Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, United States","Division of Biostatistics and Bioinformatics, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, University of Cincinnati College of Medicine, Cincinnati, OH, United States","institution_ids":["https://openalex.org/I63135867"]},{"raw_affiliation_string":"Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States","institution_ids":["https://openalex.org/I1285204247"]},{"raw_affiliation_string":"Division of Biostatistics and Bioinformatics, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH, United States","institution_ids":["https://openalex.org/I63135867"]},{"raw_affiliation_string":"Department of Biomedical Informatics, University of Cincinnati College of Medicine, United States","institution_ids":["https://openalex.org/I63135867"]},{"raw_affiliation_string":"Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, United States","institution_ids":["https://openalex.org/I1285204247"]},{"raw_affiliation_string":"Division of Biostatistics and Bioinformatics, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, United States","institution_ids":["https://openalex.org/I63135867"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003035727","display_name":"Juana Serrano\u2010L\u00f3pez","orcid":"https://orcid.org/0000-0001-8140-9040","observed_orcids":["https://orcid.org/0000-0001-8140-9040"]},"institutions":[{"id":"https://openalex.org/I4210129357","display_name":"Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz","ror":"https://ror.org/049nvyb15","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210129357"]},{"id":"https://openalex.org/I4405264755","display_name":"Instituto de Investigaci\u00f3n Sanitaria Fundaci\u00f3n Jim\u00e9nez D\u00edaz","ror":"https://ror.org/02whsjy88","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210129357","https://openalex.org/I4405264755"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Juana Serrano L\u00f3pez","raw_affiliation_strings":["Experimental Hematology Laboratory, IIS Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Madrid, Spain","Experimental Hematology Laboratory, IIS Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Hematology Laboratory, IIS Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Madrid, Spain","institution_ids":["https://openalex.org/I4210129357","https://openalex.org/I4405264755"]},{"raw_affiliation_string":"Experimental Hematology Laboratory, IIS Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Spain","institution_ids":["https://openalex.org/I4210129357","https://openalex.org/I4405264755"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5047182592"],"corresponding_institution_ids":["https://openalex.org/I25399158","https://openalex.org/I4210140007","https://openalex.org/I4405276763","https://openalex.org/I63135867"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":null,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":null,"first_page":"1049697","last_page":"1049697"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extracellular-vesicles","display_name":"extracellular vesicles","score":1.0},{"id":"https://openalex.org/keywords/precision-medicine","display_name":"precision medicine","score":0.8740000128746033},{"id":"https://openalex.org/keywords/exosomes","display_name":"exosomes","score":0.996999979019165},{"id":"https://openalex.org/keywords/microvesicles","display_name":"microvesicles","score":0.9959999918937683},{"id":"https://openalex.org/keywords/apoptotic-bodies","display_name":"apoptotic bodies","score":1.0},{"id":"https://openalex.org/keywords/ev-biogenesis","display_name":"EV biogenesis","score":0.7269999980926514},{"id":"https://openalex.org/keywords/ev-cargo","display_name":"EV cargo","score":0.7580000162124634},{"id":"https://openalex.org/keywords/cell-to-cell-communication","display_name":"cell-to-cell communication","score":0.9570000171661377},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.49799999594688416},{"id":"https://openalex.org/keywords/nanomedicine","display_name":"nanomedicine","score":0.4620000123977661}],"concepts":[{"id":"https://openalex.org/C20518536","wikidata":"https://www.wikidata.org/wiki/Q6840469","display_name":"Microvesicles","level":4,"score":0.9034298658370972},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.680082380771637},{"id":"https://openalex.org/C2992929900","wikidata":"https://www.wikidata.org/wiki/Q21097485","display_name":"Extracellular vesicles","level":2,"score":0.6697321534156799},{"id":"https://openalex.org/C131934819","wikidata":"https://www.wikidata.org/wiki/Q135390","display_name":"Biogenesis","level":3,"score":0.6573113799095154},{"id":"https://openalex.org/C2909763251","wikidata":"https://www.wikidata.org/wiki/Q6840469","display_name":"Microvesicle","level":5,"score":0.5650407075881958},{"id":"https://openalex.org/C2781261824","wikidata":"https://www.wikidata.org/wiki/Q903634","display_name":"Exosome","level":5,"score":0.5071630477905273},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.49375972151756287},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.4676154851913452},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.4669557511806488},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4380282163619995},{"id":"https://openalex.org/C2908689518","wikidata":"https://www.wikidata.org/wiki/Q21097485","display_name":"Extracellular vesicle","level":5,"score":0.42750898003578186},{"id":"https://openalex.org/C39944091","wikidata":"https://www.wikidata.org/wiki/Q423279","display_name":"Lipid bilayer","level":3,"score":0.42715612053871155},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4266763925552368},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35089564323425293},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.21469062566757202},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15278631448745728},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.12613892555236816},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.08454868197441101},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fmed.2022.1049697","doi":"https://doi.org/10.3389/fmed.2022.1049697","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmed.2022.1049697","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmed.2022.1049697/pdf","source":{"id":"https://openalex.org/S2597052008","display_name":"Frontiers in Medicine","issn_l":"2296-858X","issn":["2296-858X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Medicine","raw_type":"journal-article"},{"id":"pmid:36482912","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36482912","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in medicine","raw_type":"Editorial"},{"id":"pmh:oai:pubmedcentral.nih.gov:9723454","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9723454/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Med (Lausanne)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:4fef769ffe02409692ce55625e9c8435","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/4fef769ffe02409692ce55625e9c8435","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Medicine, Vol 9 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fmed.2022.1049697","doi":"https://doi.org/10.3389/fmed.2022.1049697","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmed.2022.1049697","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmed.2022.1049697/pdf","source":{"id":"https://openalex.org/S2597052008","display_name":"Frontiers in Medicine","issn_l":"2296-858X","issn":["2296-858X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3001494975","display_name":null,"funder_award_id":"N42A650870","funder_id":"https://openalex.org/F4320322817","funder_display_name":"National Research Council of Thailand"}],"funders":[{"id":"https://openalex.org/F4320322817","display_name":"National Research Council of Thailand","ror":"https://ror.org/018wfhg78"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4311020006.pdf","grobid_xml":"https://content.openalex.org/works/W4311020006.grobid-xml"},"referenced_works_count":6,"referenced_works":["https://openalex.org/W2900756811","https://openalex.org/W2924762180","https://openalex.org/W4220679639","https://openalex.org/W4281567633","https://openalex.org/W4289110214","https://openalex.org/W4295067309"],"related_works":["https://openalex.org/W3111531493","https://openalex.org/W2800276689","https://openalex.org/W6949097836","https://openalex.org/W2960944802","https://openalex.org/W7222855682","https://openalex.org/W4401800076","https://openalex.org/W2915553971","https://openalex.org/W2746973370","https://openalex.org/W7213939299","https://openalex.org/W3146363327"],"abstract_inverted_index":{"Extracellular":[0],"vesicles":[1],"(EVs)":[2],"have":[3,35],"become":[4],"a":[5,15,31],"growing":[6],"topic":[7],"of":[8],"discussion":[9],"in":[10,53,83],"precision":[11],"medicine.":[12],"EVs":[13,34,67,79],"is":[14],"generic":[16],"term":[17],"for":[18],"non-replicated,":[19],"lipid":[20],"bilayer":[21],"encapsulated":[22],"nano-scaled":[23],"particles":[24],"released":[25],"from":[26],"living":[27],"cells":[28],"(1).":[29,61],"In":[30,77],"broad":[32],"view,":[33],"three":[36],"subtypes,":[37],"i.e.,":[38],"exosomes":[39],"(small":[40],"EVs),":[41,44,50],"microvesicles":[42],"(large":[43],"and":[45,58,75,92],"apoptotic":[46],"bodies":[47],"(apoptotic":[48],"cell-derived":[49],"which":[51],"differ":[52],"biogenesis":[54],"pathways,":[55],"particle":[56],"properties,":[57],"molecular":[59],"markers":[60],"Depending":[62],"on":[63],"their":[64],"cell":[65],"hosts,":[66],"contain":[68],"functional":[69],"cargos,":[70],"including":[71],"proteins,":[72],"nucleic":[73],"acids,":[74],"lipids.":[76],"biology,":[78],"play":[80],"crucial":[81],"roles":[82],"cell-to-cell":[84],"communication,":[85],"maintaining":[86],"cellular":[87],"homeostasis,":[88],"regulating":[89],"tissue":[90],"development,":[91],"modulating":[93],"33":[94],"immune":[95],"functions":[96],"(1)(2)(3)(4)(5)":[97]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-12-22T00:00:00"}