{"id":"https://openalex.org/W4310080468","doi":"https://doi.org/10.1007/s10803-022-05784-9","title":"Efficacy of Sulforaphane in Treatment of Children with Autism Spectrum Disorder: A Randomized Double-Blind Placebo-Controlled Multi-center Trial","display_name":"Efficacy of Sulforaphane in Treatment of Children with Autism Spectrum Disorder: A Randomized Double-Blind Placebo-Controlled Multi-center Trial","publication_year":2022,"publication_date":"2022-11-24","ids":{"openalex":"https://openalex.org/W4310080468","doi":"https://doi.org/10.1007/s10803-022-05784-9","pmid":"https://pubmed.ncbi.nlm.nih.gov/36427174"},"language":"en","primary_location":{"id":"doi:10.1007/s10803-022-05784-9","doi":"https://doi.org/10.1007/s10803-022-05784-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10803-022-05784-9","pdf_url":null,"source":{"id":"https://openalex.org/S181451930","display_name":"Journal of Autism and Developmental Disorders","issn_l":"0162-3257","issn":["0162-3257","1573-3432"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Autism and Developmental Disorders","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007906401","display_name":"Jianjun Ou","orcid":"https://orcid.org/0000-0002-0611-7715","observed_orcids":["https://orcid.org/0000-0002-0611-7715"]},"institutions":[{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159426","display_name":"Hunan Institute of Mental Health","ror":"https://ror.org/05psxec48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159426"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianjun Ou","raw_affiliation_strings":["China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China"],"raw_orcid":"https://orcid.org/0000-0002-0611-7715","affiliations":[{"raw_affiliation_string":"China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210153856"]},{"raw_affiliation_string":"Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210159426"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100782718","display_name":"Robert C. Smith","orcid":"https://orcid.org/0000-0002-4933-4162","observed_orcids":["https://orcid.org/0000-0002-4933-4162"]},"institutions":[{"id":"https://openalex.org/I125043107","display_name":"Nathan Kline Institute for Psychiatric Research","ror":"https://ror.org/01s434164","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I125043107"]},{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert C. Smith","raw_affiliation_strings":["Department of Psychiatry, New York University School of Medicine, New York, NY, USA","Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]},{"raw_affiliation_string":"Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA","institution_ids":["https://openalex.org/I125043107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081313836","display_name":"Russell H. Tobe","orcid":"https://orcid.org/0000-0002-7738-8344","observed_orcids":["https://orcid.org/0000-0002-7738-8344"]},"institutions":[{"id":"https://openalex.org/I125043107","display_name":"Nathan Kline Institute for Psychiatric Research","ror":"https://ror.org/01s434164","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I125043107"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Russell H. Tobe","raw_affiliation_strings":["Department of Psychiatry, Columbia University, New York, NY, USA","Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Columbia University, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA","institution_ids":["https://openalex.org/I125043107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029040262","display_name":"Jingjing Lin","orcid":"https://orcid.org/0000-0002-3526-8766","observed_orcids":["https://orcid.org/0000-0002-3526-8766"]},"institutions":[{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159426","display_name":"Hunan Institute of Mental Health","ror":"https://ror.org/05psxec48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159426"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingjing Lin","raw_affiliation_strings":["China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210153856"]},{"raw_affiliation_string":"Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210159426"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047428186","display_name":"Jen Arriaza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jen Arriaza","raw_affiliation_strings":["School of Professional Studies, New York University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Professional Studies, New York University, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073144179","display_name":"Jed W. Fahey","orcid":"https://orcid.org/0000-0002-2129-1834","observed_orcids":["https://orcid.org/0000-0002-2129-1834"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jed W. Fahey","raw_affiliation_strings":["Departments of Medicine, Psychiatry and Behavioral Sciences, and Pharmacology & Molecular Sciences, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine, Psychiatry and Behavioral Sciences, and Pharmacology & Molecular Sciences, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101781031","display_name":"Ruiting Liu","orcid":"https://orcid.org/0000-0002-1028-3214","observed_orcids":["https://orcid.org/0000-0002-1028-3214"]},"institutions":[{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159426","display_name":"Hunan Institute of Mental Health","ror":"https://ror.org/05psxec48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159426"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruiting Liu","raw_affiliation_strings":["China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210153856"]},{"raw_affiliation_string":"Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210159426"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ying Zeng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159426","display_name":"Hunan Institute of Mental Health","ror":"https://ror.org/05psxec48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159426"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Zeng","raw_affiliation_strings":["China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210153856"]},{"raw_affiliation_string":"Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210159426"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100387407","display_name":"Yanan Liu","orcid":"https://orcid.org/0000-0002-6731-9871","observed_orcids":["https://orcid.org/0000-0002-6731-9871"]},"institutions":[{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159426","display_name":"Hunan Institute of Mental Health","ror":"https://ror.org/05psxec48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159426"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanan Liu","raw_affiliation_strings":["China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210153856"]},{"raw_affiliation_string":"Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210159426"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014937281","display_name":"Lian Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159426","display_name":"Hunan Institute of Mental Health","ror":"https://ror.org/05psxec48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159426"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lian Huang","raw_affiliation_strings":["China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210153856"]},{"raw_affiliation_string":"Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210159426"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083865826","display_name":"Yidong Shen","orcid":"https://orcid.org/0000-0002-5439-3757","observed_orcids":["https://orcid.org/0000-0002-5439-3757"]},"institutions":[{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159426","display_name":"Hunan Institute of Mental Health","ror":"https://ror.org/05psxec48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159426"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yidong Shen","raw_affiliation_strings":["China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210153856"]},{"raw_affiliation_string":"Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210159426"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100347633","display_name":"Yamin Li","orcid":"https://orcid.org/0000-0002-8396-5208","observed_orcids":["https://orcid.org/0000-0002-8396-5208"]},"institutions":[{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159426","display_name":"Hunan Institute of Mental Health","ror":"https://ror.org/05psxec48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159426"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yamin Li","raw_affiliation_strings":["China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210153856"]},{"raw_affiliation_string":"Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China","institution_ids":[]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210159426"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017539276","display_name":"Daomeng Cheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92039509","display_name":"Guangzhou Medical University","ror":"https://ror.org/00zat6v61","country_code":"CN","type":"education","lineage":["https://openalex.org/I92039509"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Daomeng Cheng","raw_affiliation_strings":["The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, 510370, Guangdong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, 510370, Guangdong, China","institution_ids":["https://openalex.org/I92039509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007971433","display_name":"Brian S. Cornblatt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130182","display_name":"Nutramax Laboratories (United States)","ror":"https://ror.org/04c2v9g63","country_code":"US","type":"company","lineage":["https://openalex.org/I4210130182"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian Cornblatt","raw_affiliation_strings":["Nutramax Laboratories, Consumer Care, Inc., Edgewood, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nutramax Laboratories, Consumer Care, Inc., Edgewood, MD, USA","institution_ids":["https://openalex.org/I4210130182"]}]},{"author_position":"middle","author":{"id":null,"display_name":"John M. Davis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John M. Davis","raw_affiliation_strings":["Department of Psychiatry, University of Illinois, Psychiatric Institute, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of Illinois, Psychiatric Institute, Chicago, IL, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060611926","display_name":"Jingping Zhao","orcid":"https://orcid.org/0000-0001-5940-653X","observed_orcids":["https://orcid.org/0000-0001-5940-653X"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159426","display_name":"Hunan Institute of Mental Health","ror":"https://ror.org/05psxec48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159426"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jingping Zhao","raw_affiliation_strings":["China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China. zhaojingping@csu.edu.cn","Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China. zhaojingping@csu.edu.cn","Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China. zhaojingping@csu.edu.cn","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China. zhaojingping@csu.edu.cn","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China. zhaojingping@csu.edu.cn","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China. zhaojingping@csu.edu.cn","institution_ids":["https://openalex.org/I4210153856"]},{"raw_affiliation_string":"Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China. zhaojingping@csu.edu.cn","institution_ids":[]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China. zhaojingping@csu.edu.cn","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210159426"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005130890","display_name":"Renrong Wu","orcid":"https://orcid.org/0000-0003-1758-4738","observed_orcids":["https://orcid.org/0000-0003-1758-4738"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]},{"id":"https://openalex.org/I4210159426","display_name":"Hunan Institute of Mental Health","ror":"https://ror.org/05psxec48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159426"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Renrong Wu","raw_affiliation_strings":["China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China. wurenrong@csu.edu.cn","Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China. wurenrong@csu.edu.cn","Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China. wurenrong@csu.edu.cn","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China. wurenrong@csu.edu.cn","Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China. wurenrong@csu.edu.cn","Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China National Technology Institute on Mental Disorders, Changsha, 410011, Hunan, China. wurenrong@csu.edu.cn","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Middle Renmin Road, Changsha, 410011, Hunan, China. wurenrong@csu.edu.cn","institution_ids":["https://openalex.org/I4210153856"]},{"raw_affiliation_string":"Hunan Key Laboratory of Psychiatry and Mental Health, Changsha, 410011, Hunan, China. wurenrong@csu.edu.cn","institution_ids":[]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China. wurenrong@csu.edu.cn","institution_ids":["https://openalex.org/I139660479"]},{"raw_affiliation_string":"Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China. wurenrong@csu.edu.cn","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"raw_affiliation_string":"Hunan Medical Center for Mental Health, Changsha, 410011, Hunan, China","institution_ids":["https://openalex.org/I4210159426"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046690265","display_name":"Hua Jin","orcid":"https://orcid.org/0000-0003-0181-5060","observed_orcids":["https://orcid.org/0000-0003-0181-5060"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210099595","display_name":"VA San Diego Healthcare System","ror":"https://ror.org/00znqwq11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210099595","https://openalex.org/I4210138663"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hua Jin","raw_affiliation_strings":["Department of Psychiatry, University of California San Diego and Psychiatric Service, VA San Diego Healthcare System, San Diego, CA, USA. hjin@health.ucsd.edu","Department of Psychiatry, University of California San Diego and Psychiatric Service, VA San Diego Healthcare System, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of California San Diego and Psychiatric Service, VA San Diego Healthcare System, San Diego, CA, USA. hjin@health.ucsd.edu","institution_ids":["https://openalex.org/I36258959","https://openalex.org/I4210099595"]},{"raw_affiliation_string":"Department of Psychiatry, University of California San Diego and Psychiatric Service, VA San Diego Healthcare System, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959","https://openalex.org/I4210099595"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5005130890","https://openalex.org/A5046690265","https://openalex.org/A5060611926"],"corresponding_institution_ids":["https://openalex.org/I139660479","https://openalex.org/I19820366","https://openalex.org/I36258959","https://openalex.org/I4210099595","https://openalex.org/I4210106477","https://openalex.org/I4210153856","https://openalex.org/I4210159426"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":null,"fwci":2.9144,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.92052924,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"54","issue":"2","first_page":"628","last_page":"641"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13393","display_name":"Child Nutrition and Feeding Issues","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sulforaphane","display_name":"sulforaphane","score":1.0},{"id":"https://openalex.org/keywords/autism-spectrum-disorder","display_name":"autism spectrum disorder","score":1.0},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.9200000166893005},{"id":"https://openalex.org/keywords/dietary-supplementation","display_name":"dietary supplementation","score":0.5590000152587891},{"id":"https://openalex.org/keywords/core-symptoms","display_name":"core symptoms","score":0.5830000042915344},{"id":"https://openalex.org/keywords/clinician-rated-scales","display_name":"clinician-rated scales","score":0.9909999966621399},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.5920000076293945},{"id":"https://openalex.org/keywords/safety-and-tolerability","display_name":"safety and tolerability","score":0.875},{"id":"https://openalex.org/keywords/intelligence-level","display_name":"intelligence level","score":0.5529999732971191}],"concepts":[{"id":"https://openalex.org/C2780841255","wikidata":"https://www.wikidata.org/wiki/Q424489","display_name":"Sulforaphane","level":2,"score":0.9448990225791931},{"id":"https://openalex.org/C205778803","wikidata":"https://www.wikidata.org/wiki/Q38404","display_name":"Autism","level":2,"score":0.7506357431411743},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.7003720998764038},{"id":"https://openalex.org/C2778538070","wikidata":"https://www.wikidata.org/wiki/Q1436063","display_name":"Autism spectrum disorder","level":3,"score":0.6816408634185791},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6426171064376831},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5992078185081482},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.45119568705558777},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.4204562306404114},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.40383753180503845},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2779068350791931},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18154305219650269},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.060422301292419434},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000067877","descriptor_name":"Autism Spectrum Disorder","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013454","descriptor_name":"Sulfoxides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017879","descriptor_name":"Isothiocyanates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D017879","descriptor_name":"Isothiocyanates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10803-022-05784-9","doi":"https://doi.org/10.1007/s10803-022-05784-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10803-022-05784-9","pdf_url":null,"source":{"id":"https://openalex.org/S181451930","display_name":"Journal of Autism and Developmental Disorders","issn_l":"0162-3257","issn":["0162-3257","1573-3432"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Autism and Developmental Disorders","raw_type":"journal-article"},{"id":"pmid:36427174","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36427174","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of autism and developmental disorders","raw_type":"Randomized Controlled Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[{"id":"https://openalex.org/G2232348502","display_name":null,"funder_award_id":"81974217","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3150225807","display_name":null,"funder_award_id":"2020JJ5825","funder_id":"https://openalex.org/F4320322843","funder_display_name":"Natural Science Foundation of\u00a0Hunan Province"},{"id":"https://openalex.org/G7321163244","display_name":null,"funder_award_id":"2016YFC1306900","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G8633075399","display_name":null,"funder_award_id":"81622018","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322843","display_name":"Natural Science Foundation of\u00a0Hunan Province","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1588132147","https://openalex.org/W1924879152","https://openalex.org/W1968430210","https://openalex.org/W1973801758","https://openalex.org/W1982393217","https://openalex.org/W1994275409","https://openalex.org/W2006393891","https://openalex.org/W2012548747","https://openalex.org/W2025450822","https://openalex.org/W2046875666","https://openalex.org/W2053488505","https://openalex.org/W2074287826","https://openalex.org/W2077088299","https://openalex.org/W2092083729","https://openalex.org/W2110065044","https://openalex.org/W2111403994","https://openalex.org/W2155746365","https://openalex.org/W2581846413","https://openalex.org/W2765709637","https://openalex.org/W2766411406","https://openalex.org/W2788509207","https://openalex.org/W2799436675","https://openalex.org/W2805634078","https://openalex.org/W2806885708","https://openalex.org/W2886989735","https://openalex.org/W2956016099","https://openalex.org/W2978930973","https://openalex.org/W2982291262","https://openalex.org/W3014473638","https://openalex.org/W3019064788","https://openalex.org/W3114516680","https://openalex.org/W3164998977","https://openalex.org/W3216151710","https://openalex.org/W4234687407","https://openalex.org/W4248415074","https://openalex.org/W4253870456","https://openalex.org/W4283836188","https://openalex.org/W4299602173"],"related_works":["https://openalex.org/W4319795467","https://openalex.org/W3164998977","https://openalex.org/W2803210547","https://openalex.org/W6902044260","https://openalex.org/W7046909317","https://openalex.org/W2493301227","https://openalex.org/W2025450822","https://openalex.org/W2746333602","https://openalex.org/W4411009226","https://openalex.org/W2766411406"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-11-30T00:00:00"}