{"id":"https://openalex.org/W4310071647","doi":"https://doi.org/10.1016/j.eclinm.2022.101756","title":"Patient-reported outcomes for the Intergroup Sentinel Mamma study (INSEMA): a randomised trial with persistent impact of axillary surgery on arm and breast symptoms in patients with early breast cancer","display_name":"Patient-reported outcomes for the Intergroup Sentinel Mamma study (INSEMA): a randomised trial with persistent impact of axillary surgery on arm and breast symptoms in patients with early breast cancer","publication_year":2022,"publication_date":"2022-11-25","ids":{"openalex":"https://openalex.org/W4310071647","doi":"https://doi.org/10.1016/j.eclinm.2022.101756","pmid":"https://pubmed.ncbi.nlm.nih.gov/36457648"},"language":"en","primary_location":{"id":"doi:10.1016/j.eclinm.2022.101756","doi":"https://doi.org/10.1016/j.eclinm.2022.101756","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.eclinm.2022.101756","pdf_url":"http://www.thelancet.com/article/S2589537022004850/pdf","source":{"id":"https://openalex.org/S2898347799","display_name":"EClinicalMedicine","issn_l":"2589-5370","issn":["2589-5370"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eClinicalMedicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.thelancet.com/article/S2589537022004850/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050978422","display_name":"Toralf Reimer","orcid":"https://orcid.org/0000-0003-3014-370X","observed_orcids":["https://orcid.org/0000-0003-3014-370X"]},"institutions":[{"id":"https://openalex.org/I4665924","display_name":"University of Rostock","ror":"https://ror.org/03zdwsf69","country_code":"DE","type":"education","lineage":["https://openalex.org/I4665924"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Toralf Reimer","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Rostock, S\u00fcdring 81, 18059 Rostock, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Rostock, S\u00fcdring 81, 18059 Rostock, Germany","institution_ids":["https://openalex.org/I4665924"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079614405","display_name":"Angrit Stachs","orcid":"https://orcid.org/0000-0002-6035-130X","observed_orcids":["https://orcid.org/0000-0002-6035-130X"]},"institutions":[{"id":"https://openalex.org/I4665924","display_name":"University of Rostock","ror":"https://ror.org/03zdwsf69","country_code":"DE","type":"education","lineage":["https://openalex.org/I4665924"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Angrit Stachs","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Rostock, S\u00fcdring 81, 18059 Rostock, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Rostock, S\u00fcdring 81, 18059 Rostock, Germany","institution_ids":["https://openalex.org/I4665924"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069749411","display_name":"Kristina Veselinovic","orcid":"https://orcid.org/0000-0002-2959-0580","observed_orcids":["https://orcid.org/0000-0002-2959-0580"]},"institutions":[{"id":"https://openalex.org/I196349391","display_name":"Universit\u00e4t Ulm","ror":"https://ror.org/032000t02","country_code":"DE","type":"education","lineage":["https://openalex.org/I196349391"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kristina Veselinovic","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Ulm, Prittwitzstr. 43, 89075 Ulm, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Ulm, Prittwitzstr. 43, 89075 Ulm, Germany","institution_ids":["https://openalex.org/I196349391"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030915541","display_name":"Silke Polata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210133220","display_name":"Waldkrankenhaus Protestant Hospital","ror":"https://ror.org/03afbx254","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210133220"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Silke Polata","raw_affiliation_strings":["Breast Center, Evangelisches Waldkrankenhaus Spandau, Stadtrandstr. 555, 13589 Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Breast Center, Evangelisches Waldkrankenhaus Spandau, Stadtrandstr. 555, 13589 Berlin, Germany","institution_ids":["https://openalex.org/I4210133220"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100661928","display_name":"Thomas M. M\u00fcller","orcid":"https://orcid.org/0000-0001-8726-6052","observed_orcids":["https://orcid.org/0000-0001-8726-6052"]},"institutions":[{"id":"https://openalex.org/I4210091155","display_name":"Klinikum Hanau","ror":"https://ror.org/00gw6fh23","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210091155"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas M\u00fcller","raw_affiliation_strings":["Women's Hospital, Klinikum Hanau GmbH, Leimenstr. 20, 63450 Hanau, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Women's Hospital, Klinikum Hanau GmbH, Leimenstr. 20, 63450 Hanau, Germany","institution_ids":["https://openalex.org/I4210091155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021367756","display_name":"Thorsten K\u00fchn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117167","display_name":"Klinikum Esslingen","ror":"https://ror.org/02a2sfd38","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210117167"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thorsten K\u00fchn","raw_affiliation_strings":["Women's Hospital, Klinikum Esslingen, Hirschlandstr. 97, 73730 Esslingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Women's Hospital, Klinikum Esslingen, Hirschlandstr. 97, 73730 Esslingen, Germany","institution_ids":["https://openalex.org/I4210117167"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085380597","display_name":"Joerg Heil","orcid":"https://orcid.org/0000-0002-4684-9099","observed_orcids":["https://orcid.org/0000-0002-4684-9099"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J\u00f6rg Heil","raw_affiliation_strings":["Breast Unit, University Hospital, University of Heidelberg, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Breast Unit, University Hospital, University of Heidelberg, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909","https://openalex.org/I2802164966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029020419","display_name":"Beyhan Ataseven","orcid":"https://orcid.org/0000-0002-2823-7590","observed_orcids":["https://orcid.org/0000-0002-2823-7590"]},"institutions":[{"id":"https://openalex.org/I3018771216","display_name":"LMU Klinikum","ror":"https://ror.org/02jet3w32","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4210146447","display_name":"Kliniken Essen-Mitte","ror":"https://ror.org/03v958f45","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210146447"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Beyhan Ataseven","raw_affiliation_strings":["Department of Gynecology and Gynecologic Oncology, Evang. Kliniken Essen-Mitte, Henricistr. 92, 45136 Essen, Germany","Department of Obstetrics and Gynecology, LMU University Hospital, Marchioninistr. 15, 81377 Munich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology and Gynecologic Oncology, Evang. Kliniken Essen-Mitte, Henricistr. 92, 45136 Essen, Germany","institution_ids":["https://openalex.org/I4210146447"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, LMU University Hospital, Marchioninistr. 15, 81377 Munich, Germany","institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006899638","display_name":"Roland Reitsamer","orcid":"https://orcid.org/0000-0001-6330-2653","observed_orcids":["https://orcid.org/0000-0001-6330-2653"]},"institutions":[{"id":"https://openalex.org/I27945538","display_name":"Paracelsus Medical University","ror":"https://ror.org/03z3mg085","country_code":"AT","type":"education","lineage":["https://openalex.org/I27945538"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Roland Reitsamer","raw_affiliation_strings":["Breast Center, LKH Salzburg, Paracelsus Medical University Clinics, M\u00fcllner Hauptstr. 48, A-5020 Salzburg, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Breast Center, LKH Salzburg, Paracelsus Medical University Clinics, M\u00fcllner Hauptstr. 48, A-5020 Salzburg, Austria","institution_ids":["https://openalex.org/I27945538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079287119","display_name":"Guido Hildebrandt","orcid":"https://orcid.org/0000-0002-0498-2692","observed_orcids":["https://orcid.org/0000-0002-0498-2692"]},"institutions":[{"id":"https://openalex.org/I4665924","display_name":"University of Rostock","ror":"https://ror.org/03zdwsf69","country_code":"DE","type":"education","lineage":["https://openalex.org/I4665924"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Guido Hildebrandt","raw_affiliation_strings":["Department of Radiotherapy, University of Rostock, S\u00fcdring 75, 18059 Rostock, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiotherapy, University of Rostock, S\u00fcdring 75, 18059 Rostock, Germany","institution_ids":["https://openalex.org/I4665924"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017213717","display_name":"Michael Knauer","orcid":"https://orcid.org/0000-0002-6266-9194","observed_orcids":["https://orcid.org/0000-0002-6266-9194"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Knauer","raw_affiliation_strings":["Brustzentrum Ost, Rohrschacher Str. 286, CH-9016 St. Gallen, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brustzentrum Ost, Rohrschacher Str. 286, CH-9016 St. Gallen, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067246293","display_name":"Michael Golatta","orcid":"https://orcid.org/0000-0002-2605-0060","observed_orcids":["https://orcid.org/0000-0002-2605-0060"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Golatta","raw_affiliation_strings":["Breast Unit, Sankt Elisabeth Hospital, Max-Reger-Str. 5-7, 69121 Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Breast Unit, Sankt Elisabeth Hospital, Max-Reger-Str. 5-7, 69121 Heidelberg, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042364191","display_name":"Andrea Stefek","orcid":"https://orcid.org/0000-0003-3596-8188","observed_orcids":["https://orcid.org/0000-0003-3596-8188"]},"institutions":[{"id":"https://openalex.org/I4210100128","display_name":"Die Johanniter","ror":"https://ror.org/0125qer46","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4210100128"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andrea Stefek","raw_affiliation_strings":["Women's Hospital, Johanniter-Hospital Stendal, Wendstr. 31, 39576 Stendal, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Women's Hospital, Johanniter-Hospital Stendal, Wendstr. 31, 39576 Stendal, Germany","institution_ids":["https://openalex.org/I4210100128"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112748757","display_name":"Dirk-Michael Zahm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094380","display_name":"SRH Wald-Klinikum Gera","ror":"https://ror.org/00q236z92","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094380"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dirk-Michael Zahm","raw_affiliation_strings":["Breast Center, SRH Waldklinikum Gera, Str. des Friedens 122, 07548 Gera, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Breast Center, SRH Waldklinikum Gera, Str. des Friedens 122, 07548 Gera, Germany","institution_ids":["https://openalex.org/I4210094380"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055136263","display_name":"Marc Thill","orcid":"https://orcid.org/0000-0002-8800-8044","observed_orcids":["https://orcid.org/0000-0002-8800-8044"]},"institutions":[{"id":"https://openalex.org/I4210148372","display_name":"Agaplesion Markus Hospital","ror":"https://ror.org/04hd04g86","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210117177","https://openalex.org/I4210148372"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Marc Thill","raw_affiliation_strings":["Department of Gynecology and Gynecological Oncology, Agaplesion Markus Hospital, W.-Epstein-Str. 4, 60431 Frankfurt/Main, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology and Gynecological Oncology, Agaplesion Markus Hospital, W.-Epstein-Str. 4, 60431 Frankfurt/Main, Germany","institution_ids":["https://openalex.org/I4210148372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057181684","display_name":"Valentina Nekljudova","orcid":"https://orcid.org/0000-0002-2801-7387","observed_orcids":["https://orcid.org/0000-0002-2801-7387"]},"institutions":[{"id":"https://openalex.org/I4210130803","display_name":"German Breast Group","ror":"https://ror.org/03c8hnh70","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4210130803"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Valentina Nekljudova","raw_affiliation_strings":["German Breast Group, Dornhofstr. 10, 63263 Neu-Isenburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"German Breast Group, Dornhofstr. 10, 63263 Neu-Isenburg, Germany","institution_ids":["https://openalex.org/I4210130803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050549111","display_name":"David A. Krug","orcid":"https://orcid.org/0000-0001-8811-5416","observed_orcids":["https://orcid.org/0000-0001-8811-5416"]},"institutions":[{"id":"https://openalex.org/I4210112713","display_name":"University Hospital Schleswig-Holstein","ror":"https://ror.org/01tvm6f46","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210112713"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"David Krug","raw_affiliation_strings":["Department of Radiation Oncology, University Hospital Schleswig-Holstein, Arnold-Heller-Str., 24105 Kiel, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University Hospital Schleswig-Holstein, Arnold-Heller-Str., 24105 Kiel, Germany","institution_ids":["https://openalex.org/I4210112713"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087559224","display_name":"Sibylle Loibl","orcid":"https://orcid.org/0000-0001-6488-4958","observed_orcids":["https://orcid.org/0000-0001-6488-4958"]},"institutions":[{"id":"https://openalex.org/I4210130803","display_name":"German Breast Group","ror":"https://ror.org/03c8hnh70","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4210130803"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sibylle Loibl","raw_affiliation_strings":["German Breast Group, Dornhofstr. 10, 63263 Neu-Isenburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"German Breast Group, Dornhofstr. 10, 63263 Neu-Isenburg, Germany","institution_ids":["https://openalex.org/I4210130803"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103808942","display_name":"Bernd Gerber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4665924","display_name":"University of Rostock","ror":"https://ror.org/03zdwsf69","country_code":"DE","type":"education","lineage":["https://openalex.org/I4665924"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bernd Gerber","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Rostock, S\u00fcdring 81, 18059 Rostock, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Rostock, S\u00fcdring 81, 18059 Rostock, Germany","institution_ids":["https://openalex.org/I4665924"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":16,"corresponding_author_ids":["https://openalex.org/A5050978422"],"corresponding_institution_ids":["https://openalex.org/I4665924"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":{"value":4500,"currency":"USD","value_usd":4500},"fwci":6.4402,"has_fulltext":true,"cited_by_count":90,"citation_normalized_percentile":{"value":0.9817746,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"55","issue":null,"first_page":"101756","last_page":"101756"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sentinel-lymph-node-biopsy","display_name":"sentinel lymph node biopsy","score":0.8600000143051147},{"id":"https://openalex.org/keywords/axillary-lymph-node-dissection","display_name":"axillary lymph node dissection","score":0.9980000257492065},{"id":"https://openalex.org/keywords/early-breast-cancer","display_name":"early breast cancer","score":0.7829999923706055},{"id":"https://openalex.org/keywords/node-negative-breast-cancer","display_name":"node-negative breast cancer","score":0.8930000066757202},{"id":"https://openalex.org/keywords/patient-reported-outcomes","display_name":"patient-reported outcomes","score":0.8690000176429749},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.9789999723434448},{"id":"https://openalex.org/keywords/arm-symptoms","display_name":"arm symptoms","score":0.8519999980926514},{"id":"https://openalex.org/keywords/breast-symptoms","display_name":"breast symptoms","score":0.8920000195503235},{"id":"https://openalex.org/keywords/eortc-qlq-c30","display_name":"EORTC QLQ-C30","score":0.8270000219345093},{"id":"https://openalex.org/keywords/arm-swelling","display_name":"arm swelling","score":0.4620000123977661},{"id":"https://openalex.org/keywords/postoperative-pain","display_name":"postoperative pain","score":0.6710000038146973},{"id":"https://openalex.org/keywords/non-inferiority","display_name":"non-inferiority","score":0.7940000295639038},{"id":"https://openalex.org/keywords/omission-of-axillary-surgery","display_name":"omission of axillary surgery","score":0.8349999785423279},{"id":"https://openalex.org/keywords/macrometastasis","display_name":"macrometastases","score":0.8759999871253967}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.987480640411377},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7318979501724243},{"id":"https://openalex.org/C2777704003","wikidata":"https://www.wikidata.org/wiki/Q4959802","display_name":"Breast surgery","level":4,"score":0.5369211435317993},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5212231874465942},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.49551379680633545},{"id":"https://openalex.org/C2776608951","wikidata":"https://www.wikidata.org/wiki/Q499","display_name":"Axilla","level":4,"score":0.48101338744163513},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.46977800130844116},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.23618263006210327},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1920042634010315}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.eclinm.2022.101756","doi":"https://doi.org/10.1016/j.eclinm.2022.101756","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.eclinm.2022.101756","pdf_url":"http://www.thelancet.com/article/S2589537022004850/pdf","source":{"id":"https://openalex.org/S2898347799","display_name":"EClinicalMedicine","issn_l":"2589-5370","issn":["2589-5370"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eClinicalMedicine","raw_type":"journal-article"},{"id":"pmid:36457648","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36457648","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EClinicalMedicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9706517","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9706517","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"eClinicalMedicine","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:f069c43c7ae04eda9c27c5dbb92c3e9a","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/f069c43c7ae04eda9c27c5dbb92c3e9a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"EClinicalMedicine, Vol 55, Iss , Pp 101756- (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.eclinm.2022.101756","doi":"https://doi.org/10.1016/j.eclinm.2022.101756","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.eclinm.2022.101756","pdf_url":"http://www.thelancet.com/article/S2589537022004850/pdf","source":{"id":"https://openalex.org/S2898347799","display_name":"EClinicalMedicine","issn_l":"2589-5370","issn":["2589-5370"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eClinicalMedicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.699999988079071}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4433954607","display_name":null,"funder_award_id":"110580","funder_id":"https://openalex.org/F4320323556","funder_display_name":"Deutsche Krebshilfe"},{"id":"https://openalex.org/G7117775205","display_name":null,"funder_award_id":"70110580","funder_id":"https://openalex.org/F4320323556","funder_display_name":"Deutsche Krebshilfe"}],"funders":[{"id":"https://openalex.org/F4320323556","display_name":"Deutsche Krebshilfe","ror":"https://ror.org/01wxdd722"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4310071647.pdf","grobid_xml":"https://content.openalex.org/works/W4310071647.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W572930562","https://openalex.org/W1848007259","https://openalex.org/W1947168884","https://openalex.org/W1997393969","https://openalex.org/W2012202415","https://openalex.org/W2012301405","https://openalex.org/W2070281077","https://openalex.org/W2091707020","https://openalex.org/W2096785769","https://openalex.org/W2114349652","https://openalex.org/W2118638289","https://openalex.org/W2141595244","https://openalex.org/W2142059226","https://openalex.org/W2154806076","https://openalex.org/W2167571044","https://openalex.org/W2253618607","https://openalex.org/W2571552770","https://openalex.org/W2596288071","https://openalex.org/W2599228863","https://openalex.org/W2727636535","https://openalex.org/W2891743556","https://openalex.org/W3024084828","https://openalex.org/W3204713500","https://openalex.org/W3204889472","https://openalex.org/W4214486697"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2375164983","https://openalex.org/W2128073420","https://openalex.org/W4387710931","https://openalex.org/W2357019628","https://openalex.org/W2929138898","https://openalex.org/W2402864781","https://openalex.org/W4214593668","https://openalex.org/W2355769538","https://openalex.org/W2017883261"],"abstract_inverted_index":{"Background:":[0],"In":[1,121],"clinically":[2,191,260],"node-negative":[3,261],"breast":[4,60],"cancer":[5,61],"patients,":[6],"the":[7,12,91,104,112,122,148,157,165,175,185,218,228,236,250,255,264],"INSEMA":[8],"trial":[9],"(NCT02466737)":[10],"assessed":[11,40],"non-inferiority":[13],"of":[14,52,124,227,249,257],"avoiding":[15],"sentinel":[16],"lymph":[17,23],"node":[18,24],"biopsy":[19],"(SLNB)":[20],"or":[21],"axillary":[22,45],"dissection":[25],"(ALND).":[26],"Here":[27],"we":[28],"present":[29],"patient-reported":[30],"outcomes":[31],"(PROs)":[32],"as":[33],"a":[34],"secondary":[35],"endpoint.":[36],"Methods:":[37],"PROs":[38],"were":[39,64,82,101,109,161,242,286],"for":[41,103,156,164,195],"patients":[42,100,132,262],"with":[43,217,272],"no":[44,119,176,232,273,280],"surgery,":[46],"SLNB":[47,116,137,177,186,258,274],"alone,":[48],"and":[49,58,69,74,97,107,169,190,210,263,301],"ALND.":[50],"Quality":[51],"life":[53],"(QoL)":[54],"questionnaire":[55,230],"EORTC":[56],"QLQ-C30":[57,229],"its":[59],"module":[62],"(BR23)":[63],"used":[65],"at":[66,152,203,221],"baseline":[67],"(pre-surgery)":[68],"1,":[70],"3,":[71],"6,":[72],"12,":[73],"18":[75],"months":[76],"after":[77,129,224],"surgery.":[78,225],"The":[79],"QoL":[80,269],"scores":[81,173,194],"compared":[83],"using":[84],"repeated":[85],"measures":[86],"mixed":[87],"models":[88],"based":[89],"on":[90],"safety":[92],"set.":[93],"Findings:":[94],"Between":[95],"2015":[96],"2019,":[98],"5502":[99],"recruited":[102],"first":[105,158,251,265],"randomization,":[106],"5154":[108],"included":[110],"in":[111,179,184,198,213,259,283],"intent-to-treat":[113],"set":[114],"(4124":[115],"versus":[117,139],"1030":[118],"SLNB).":[120],"case":[123],"one":[125,222,248],"to":[126,266,305],"three":[127],"macrometastases":[128],"SLNB,":[130],"485":[131],"underwent":[133],"second":[134],"randomization":[135],"(242":[136],"alone":[138],"243":[140],"ALND).":[141],"Questionnaire":[142],"completion":[143],"response":[144],"remained":[145],"high":[146],"throughout":[147],"trial:":[149],"over":[150],"70%":[151],"all":[153,180,204,214],"time":[154],"points":[155,202],"randomization.":[159],"There":[160],"significant":[162],"differences":[163,234,282],"BRBS":[166],"(breast":[167],"symptoms)":[168,172],"BRAS":[170,196],"(arm":[171],"favoring":[174],"group":[178,187],"post-baseline":[181],"assessments.":[182],"Patients":[183,271],"showed":[188],"significantly":[189],"relevant":[192,233,281],"higher":[193],"(differences":[197],"mean":[199],"values":[200],"\u22655.0":[201],"times),":[205],"including":[206],"pain,":[207],"arm":[208,277],"swelling,":[209],"impaired":[211],"mobility":[212],"postoperative":[215],"visits,":[216],"highest":[219],"difference":[220],"month":[223],"Scoring":[226],"revealed":[231],"between":[235],"treatment":[237],"groups,":[238],"although":[239],"some":[240],"comparisons":[241],"statistically":[243],"significant.":[244],"Interpretation:":[245],"This":[246],"is":[247],"randomized":[252],"trials":[253],"investigating":[254],"omission":[256],"report":[267],"comprehensive":[268],"data.":[270],"benefitted":[275],"regarding":[276],"symptoms/functioning,":[278],"while":[279],"other":[284],"scales":[285],"seen.":[287],"Funding:":[288],"Supported":[289],"by":[290],"German":[291],"Cancer":[292],"Aid":[293],"(Deutsche":[294],"Krebshilfe,":[295],"Bonn,":[296],"Germany),":[297],"Grant":[298,302],"No.":[299,303],"110580":[300],"70110580":[304],"University":[306],"Medicine":[307],"Rostock.":[308]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":36},{"year":2024,"cited_by_count":25},{"year":2023,"cited_by_count":16}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}
