{"id":"https://openalex.org/W4309890775","doi":"https://doi.org/10.1245/s10434-022-12707-6","title":"How Biomarkers of Response to Chemotherapy Might Change Patient Management","display_name":"How Biomarkers of Response to Chemotherapy Might Change Patient Management","publication_year":2022,"publication_date":"2022-11-23","ids":{"openalex":"https://openalex.org/W4309890775","doi":"https://doi.org/10.1245/s10434-022-12707-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/36422723"},"language":"en","primary_location":{"id":"doi:10.1245/s10434-022-12707-6","doi":"https://doi.org/10.1245/s10434-022-12707-6","is_oa":true,"landing_page_url":"https://doi.org/10.1245/s10434-022-12707-6","pdf_url":"https://link.springer.com/content/pdf/10.1245/s10434-022-12707-6.pdf","source":{"id":"https://openalex.org/S177486402","display_name":"Annals of Surgical Oncology","issn_l":"1068-9265","issn":["1068-9265","1534-4681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Surgical Oncology","raw_type":"journal-article"},"volume":null,"type":"editorial","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://link.springer.com/content/pdf/10.1245/s10434-022-12707-6.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060050760","display_name":"William G. Hawkins","orcid":"https://orcid.org/0000-0001-7087-3585","observed_orcids":["https://orcid.org/0000-0001-7087-3585"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"William G. Hawkins","raw_affiliation_strings":["Department of Surgery, Washington University in St. Louis, St. Louis, MO, USA. hawkinsw@wustl.edu","Department of Surgery, Washington University in St. Louis, St. Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Washington University in St. Louis, St. Louis, MO, USA. hawkinsw@wustl.edu","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Surgery, Washington University in St. Louis, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076989398","display_name":"Chet W. Hammill","orcid":"https://orcid.org/0000-0001-9749-0824","observed_orcids":["https://orcid.org/0000-0001-9749-0824"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chet W. Hammill","raw_affiliation_strings":["Department of Surgery, Washington University in St. Louis, St. Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Washington University in St. Louis, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013995381","display_name":"Samuel J. Ballentine","orcid":"https://orcid.org/0000-0002-6339-548X","observed_orcids":["https://orcid.org/0000-0002-6339-548X"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel J. Ballentine","raw_affiliation_strings":["Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5060050760"],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"30","issue":"2","first_page":"658","last_page":"659"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/matrix-metalloproteinase-7","display_name":"matrix metalloproteinase-7","score":0.9869999885559082},{"id":"https://openalex.org/keywords/mmp-7","display_name":"MMP-7","score":0.8529999852180481},{"id":"https://openalex.org/keywords/pancreatic-cancer","display_name":"pancreatic cancer","score":0.8799999952316284},{"id":"https://openalex.org/keywords/neoadjuvant-therapy","display_name":"neoadjuvant therapy","score":0.8799999952316284},{"id":"https://openalex.org/keywords/predictive-biomarkers","display_name":"predictive biomarkers","score":0.7260000109672546},{"id":"https://openalex.org/keywords/pathological-response","display_name":"pathological response","score":0.699999988079071},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.843999981880188},{"id":"https://openalex.org/keywords/recurrence-free-survival","display_name":"recurrence-free survival","score":0.8980000019073486},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.7900000214576721},{"id":"https://openalex.org/keywords/clinical-management","display_name":"clinical management","score":0.4830000102519989}],"concepts":[{"id":"https://openalex.org/C2780140570","wikidata":"https://www.wikidata.org/wiki/Q3545481","display_name":"Surgical oncology","level":2,"score":0.8537479639053345},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8305553197860718},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5222459435462952},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4805612862110138},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.4104541838169098},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3826306462287903},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.37534037232398987},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.35344457626342773},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1245/s10434-022-12707-6","doi":"https://doi.org/10.1245/s10434-022-12707-6","is_oa":true,"landing_page_url":"https://doi.org/10.1245/s10434-022-12707-6","pdf_url":"https://link.springer.com/content/pdf/10.1245/s10434-022-12707-6.pdf","source":{"id":"https://openalex.org/S177486402","display_name":"Annals of Surgical Oncology","issn_l":"1068-9265","issn":["1068-9265","1534-4681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Surgical Oncology","raw_type":"journal-article"},{"id":"pmid:36422723","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36422723","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of surgical oncology","raw_type":"Editorial"}],"best_oa_location":{"id":"doi:10.1245/s10434-022-12707-6","doi":"https://doi.org/10.1245/s10434-022-12707-6","is_oa":true,"landing_page_url":"https://doi.org/10.1245/s10434-022-12707-6","pdf_url":"https://link.springer.com/content/pdf/10.1245/s10434-022-12707-6.pdf","source":{"id":"https://openalex.org/S177486402","display_name":"Annals of Surgical Oncology","issn_l":"1068-9265","issn":["1068-9265","1534-4681"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Surgical Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4309890775.pdf","grobid_xml":"https://content.openalex.org/works/W4309890775.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W2045859212","https://openalex.org/W2107948751","https://openalex.org/W2910090032","https://openalex.org/W3011562658","https://openalex.org/W3015954630","https://openalex.org/W3016999780","https://openalex.org/W3120848013","https://openalex.org/W4281565302"],"related_works":["https://openalex.org/W4281565302","https://openalex.org/W2891317528","https://openalex.org/W2373087593","https://openalex.org/W2918002695","https://openalex.org/W4412150678","https://openalex.org/W2266734897","https://openalex.org/W4404871885","https://openalex.org/W2291512914","https://openalex.org/W3107543730","https://openalex.org/W2063130176"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-11-29T00:00:00"}