{"id":"https://openalex.org/W4309625811","doi":"https://doi.org/10.1016/j.semarthrit.2022.152139","title":"Systematic review on the use of biologics in adult-onset still's disease","display_name":"Systematic review on the use of biologics in adult-onset still's disease","publication_year":2022,"publication_date":"2022-11-17","ids":{"openalex":"https://openalex.org/W4309625811","doi":"https://doi.org/10.1016/j.semarthrit.2022.152139","pmid":"https://pubmed.ncbi.nlm.nih.gov/36442231"},"language":"en","primary_location":{"id":"doi:10.1016/j.semarthrit.2022.152139","doi":"https://doi.org/10.1016/j.semarthrit.2022.152139","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.semarthrit.2022.152139","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0049017222001901/pdf","source":{"id":"https://openalex.org/S140349950","display_name":"Seminars in Arthritis and Rheumatism","issn_l":"0049-0172","issn":["0049-0172","1532-866X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Arthritis and Rheumatism","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S0049017222001901/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015032522","display_name":"Bruno Fautrel","orcid":"https://orcid.org/0000-0001-8845-4274","observed_orcids":["https://orcid.org/0000-0001-8845-4274"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4210133907","display_name":"Institut Pierre Louis d\u2018\u00c9pid\u00e9miologie et de Sant\u00e9 Publique","ror":"https://ror.org/02qqh1125","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bruno Fautrel","raw_affiliation_strings":["Sorbonne Universit\u00e9, INSERM UMRS 1136, Institut Pierre Louis d'Epid\u00e9miologie et de Sant\u00e9 Publique, AP-HP, H\u00f4pital Piti\u00e9 Salp\u00eatri\u00e8re, D\u00e9partement de Rhumatologie, F75013 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sorbonne Universit\u00e9, INSERM UMRS 1136, Institut Pierre Louis d'Epid\u00e9miologie et de Sant\u00e9 Publique, AP-HP, H\u00f4pital Piti\u00e9 Salp\u00eatri\u00e8re, D\u00e9partement de Rhumatologie, F75013 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210121705","https://openalex.org/I4210133907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005183724","display_name":"Jacoby V. Patterson","orcid":"https://orcid.org/0000-0001-9801-3333","observed_orcids":["https://orcid.org/0000-0001-9801-3333"]},"institutions":[{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jacoby Patterson","raw_affiliation_strings":["York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK","institution_ids":["https://openalex.org/I52099693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039537901","display_name":"Catherine Bowe","orcid":"https://orcid.org/0000-0002-2453-9866","observed_orcids":["https://orcid.org/0000-0002-2453-9866"]},"institutions":[{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Catherine Bowe","raw_affiliation_strings":["York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK. Electronic address: Catherine.bowe@york.ac.uk","York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK"],"raw_orcid":"https://orcid.org/0000-0002-2453-9866","affiliations":[{"raw_affiliation_string":"York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK. Electronic address: Catherine.bowe@york.ac.uk","institution_ids":["https://openalex.org/I52099693"]},{"raw_affiliation_string":"York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK","institution_ids":["https://openalex.org/I52099693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038764807","display_name":"Mick R. Arber","orcid":"https://orcid.org/0009-0006-4946-115X","observed_orcids":["https://orcid.org/0009-0006-4946-115X"]},"institutions":[{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mick Arber","raw_affiliation_strings":["York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK","institution_ids":["https://openalex.org/I52099693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003504334","display_name":"Julie Glanville","orcid":"https://orcid.org/0000-0002-1253-8524","observed_orcids":["https://orcid.org/0000-0002-1253-8524"]},"institutions":[{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Julie Glanville","raw_affiliation_strings":["York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK","institution_ids":["https://openalex.org/I52099693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007505998","display_name":"Stuart Mealing","orcid":"https://orcid.org/0000-0002-2564-1440","observed_orcids":["https://orcid.org/0000-0002-2564-1440"]},"institutions":[{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stuart Mealing","raw_affiliation_strings":["York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"York Health Economics Consortium, Enterprise House, Innovation Way, University of York, Heslington, York YO10 5NQ, UK","institution_ids":["https://openalex.org/I52099693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003709175","display_name":"Viviam Canon Garcia","orcid":"https://orcid.org/0009-0008-6628-9595","observed_orcids":["https://orcid.org/0009-0008-6628-9595"]},"institutions":[{"id":"https://openalex.org/I1283582996","display_name":"Novartis (Switzerland)","ror":"https://ror.org/02f9zrr09","country_code":"CH","type":"company","lineage":["https://openalex.org/I1283582996"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Viviam Canon-Garcia","raw_affiliation_strings":["Novartis Pharma, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Pharma, Basel, Switzerland","institution_ids":["https://openalex.org/I1283582996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079509107","display_name":"Laura Fagerhed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283582996","display_name":"Novartis (Switzerland)","ror":"https://ror.org/02f9zrr09","country_code":"CH","type":"company","lineage":["https://openalex.org/I1283582996"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Laura Fagerhed","raw_affiliation_strings":["Novartis Pharma, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Pharma, Basel, Switzerland","institution_ids":["https://openalex.org/I1283582996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085379052","display_name":"Hilde Rabijns","orcid":"https://orcid.org/0009-0007-5504-3293","observed_orcids":["https://orcid.org/0009-0007-5504-3293"]},"institutions":[{"id":"https://openalex.org/I1283582996","display_name":"Novartis (Switzerland)","ror":"https://ror.org/02f9zrr09","country_code":"CH","type":"company","lineage":["https://openalex.org/I1283582996"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Hilde Rabijns","raw_affiliation_strings":["Novartis Pharma, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Pharma, Basel, Switzerland","institution_ids":["https://openalex.org/I1283582996"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051871418","display_name":"Roberto Giacomelli","orcid":"https://orcid.org/0000-0003-0670-9638","observed_orcids":["https://orcid.org/0000-0003-0670-9638","https://orcid.org/0000-0002-8384-2427"]},"institutions":[{"id":"https://openalex.org/I155125353","display_name":"Universit\u00e0 Campus Bio-Medico","ror":"https://ror.org/04gqx4x78","country_code":"IT","type":"education","lineage":["https://openalex.org/I155125353"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Giacomelli","raw_affiliation_strings":["Clinical Unit of Rheumatology and Clinical Immunology, University of Rome \"Campus Biomedico\", School of Medicine, 00128 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Unit of Rheumatology and Clinical Immunology, University of Rome \"Campus Biomedico\", School of Medicine, 00128 Rome, Italy","institution_ids":["https://openalex.org/I155125353"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5039537901"],"corresponding_institution_ids":["https://openalex.org/I52099693"],"apc_list":{"value":3960,"currency":"USD","value_usd":3960},"apc_paid":{"value":3960,"currency":"USD","value_usd":3960},"fwci":0.9789,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.72484714,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"58","issue":null,"first_page":"152139","last_page":"152139"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11892","display_name":"Kawasaki Disease and Coronary Complications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adult-onset-still-s-disease","display_name":"adult-onset Still's disease","score":1.0},{"id":"https://openalex.org/keywords/biological-dmards","display_name":"biologic DMARDs","score":0.8799999952316284},{"id":"https://openalex.org/keywords/disease-modifying-antirheumatic-drugs","display_name":"disease-modifying antirheumatic drugs","score":0.8849999904632568},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.8999999761581421},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.9359999895095825},{"id":"https://openalex.org/keywords/steroid-dose-reduction","display_name":"steroid dose reduction","score":0.843999981880188},{"id":"https://openalex.org/keywords/conventional-synthetic-dmards","display_name":"conventional synthetic DMARDs","score":0.9300000071525574}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9772288799285889},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.5292329788208008},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.47872304916381836},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.46450895071029663},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34274253249168396},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001685","descriptor_name":"Biological Factors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016706","descriptor_name":"Still's Disease, Adult-Onset","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.semarthrit.2022.152139","doi":"https://doi.org/10.1016/j.semarthrit.2022.152139","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.semarthrit.2022.152139","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0049017222001901/pdf","source":{"id":"https://openalex.org/S140349950","display_name":"Seminars in Arthritis and Rheumatism","issn_l":"0049-0172","issn":["0049-0172","1532-866X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Arthritis and Rheumatism","raw_type":"journal-article"},{"id":"pmid:36442231","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36442231","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in arthritis and rheumatism","raw_type":"Systematic Review"},{"id":"pmh:oai:HAL:hal-03986635v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-03986635","pdf_url":"https://hal.science/hal-03986635v1/file/3104.pdf","source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Seminars in Arthritis and Rheumatism, 2023, 58, pp.152139. ⟨10.1016/j.semarthrit.2022.152139⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.semarthrit.2022.152139","doi":"https://doi.org/10.1016/j.semarthrit.2022.152139","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.semarthrit.2022.152139","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0049017222001901/pdf","source":{"id":"https://openalex.org/S140349950","display_name":"Seminars in Arthritis and Rheumatism","issn_l":"0049-0172","issn":["0049-0172","1532-866X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Arthritis and Rheumatism","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4309625811.pdf","grobid_xml":"https://content.openalex.org/works/W4309625811.grobid-xml"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W182517381","https://openalex.org/W1605817481","https://openalex.org/W1614943507","https://openalex.org/W1979481717","https://openalex.org/W1988043439","https://openalex.org/W1990180387","https://openalex.org/W1993879283","https://openalex.org/W2008945784","https://openalex.org/W2011589128","https://openalex.org/W2014067126","https://openalex.org/W2020594595","https://openalex.org/W2026949371","https://openalex.org/W2050446994","https://openalex.org/W2092625242","https://openalex.org/W2093315648","https://openalex.org/W2103497547","https://openalex.org/W2104164819","https://openalex.org/W2125372614","https://openalex.org/W2126719354","https://openalex.org/W2162066871","https://openalex.org/W2175199415","https://openalex.org/W2325267532","https://openalex.org/W2331916323","https://openalex.org/W2415396904","https://openalex.org/W2516819210","https://openalex.org/W2567362164","https://openalex.org/W2623126800","https://openalex.org/W2747959954","https://openalex.org/W2751495168","https://openalex.org/W2785196859","https://openalex.org/W2788608061","https://openalex.org/W2891385015","https://openalex.org/W2894765079","https://openalex.org/W2895332890","https://openalex.org/W2896493787","https://openalex.org/W2913532246","https://openalex.org/W2919152249","https://openalex.org/W2925874700","https://openalex.org/W2947812860","https://openalex.org/W2954685937","https://openalex.org/W2966763282","https://openalex.org/W2967848710","https://openalex.org/W3007774964","https://openalex.org/W3008425193","https://openalex.org/W3024510274","https://openalex.org/W3033259685","https://openalex.org/W3033701853","https://openalex.org/W3082462919","https://openalex.org/W3093330142","https://openalex.org/W3096139820","https://openalex.org/W3116053639","https://openalex.org/W3117927760","https://openalex.org/W3167044963","https://openalex.org/W3167867497","https://openalex.org/W4241964765","https://openalex.org/W4283767469","https://openalex.org/W4289594198","https://openalex.org/W4293581462","https://openalex.org/W6700515692","https://openalex.org/W6725866013","https://openalex.org/W6748798009"],"related_works":["https://openalex.org/W4391435571","https://openalex.org/W3034373143","https://openalex.org/W3093330142","https://openalex.org/W4409035974","https://openalex.org/W3044188647","https://openalex.org/W1988043439","https://openalex.org/W4394316314","https://openalex.org/W2026949371","https://openalex.org/W3165732897","https://openalex.org/W2966763282"],"abstract_inverted_index":{"This":[0,157,183],"systematic":[1],"review":[2],"(SR)":[3],"describes":[4],"the":[5,43,161,172,176],"efficacy":[6,80],"and":[7,35,64,169],"safety":[8],"of":[9,32,39,50,74,178],"biologic":[10,51],"disease":[11,21],"modifying":[12],"anti-rheumatic":[13],"drugs":[14],"(bDMARDs)":[15],"for":[16,46,97,163,202],"patients":[17,98],"with":[18,99],"adult-onset":[19],"Still's":[20],"(AOSD).":[22],"Three":[23],"randomised":[24],"controlled":[25],"trials":[26],"(RCTs),":[27],"one":[28,62],"retrospective":[29,88],"case":[30,37,89],"series":[31,38,90],"multiple":[33],"interventions,":[34],"17":[36],"single":[40],"interventions":[41,118],"met":[42],"inclusion":[44],"criteria":[45],"this":[47],"SR.":[48],"Comparisons":[49],"therapy":[52],"in":[53,61,67,167,181,189],"AOSD":[54,168],"were":[55,113],"only":[56],"available":[57],"against":[58,65],"conventional":[59,155],"DMARDs":[60],"RCT":[63],"placebo":[66],"two":[68],"RCTs.":[69],"There":[70],"was":[71,123,131],"a":[72,151],"lack":[73],"common":[75],"assessment":[76],"criteria,":[77],"meaning":[78],"treatment":[79],"across":[81],"studies":[82,103,144,166,188],"could":[83,135],"not":[84,105],"be":[85,150,198],"compared.":[86],"Uncontrolled":[87],"suggested":[91],"that":[92,133,146],"bDMARDs":[93,112,134,147,196],"have":[94],"an":[95],"effect":[96],"AOSD,":[100],"but":[101],"these":[102],"did":[104],"provide":[106],"comparative":[107,165],"data":[108,140],"to":[109,149,154,174,191],"show":[110],"whether":[111,120],"more":[114,124,199],"effective":[115,125,200],"than":[116,126],"other":[117],"or,":[119],"any":[121],"bDMARD":[122],"another":[127],"bDMARD.":[128],"However,":[129],"there":[130],"evidence":[132],"reduce":[136],"steroid":[137],"dose.":[138],"Safety":[139],"from":[141],"all":[142],"included":[143],"showed":[145],"appear":[148],"safe":[152],"alternative":[153],"DMARDs.":[156],"SR":[158],"has":[159,170],"highlighted":[160],"need":[162,173],"larger":[164],"shown":[171],"standardize":[175],"definition":[177],"therapeutic":[179],"response":[180],"AOSD.":[182,203],"would":[184],"allow":[185],"comparisons":[186],"between":[187],"order":[190],"gain":[192],"clarity":[193],"on":[194],"which":[195],"may":[197],"treatments":[201]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-11-28T00:00:00"}