{"id":"https://openalex.org/W4309091237","doi":"https://doi.org/10.3390/tomography8060224","title":"Prediction of Lung Shunt Fraction for Yttrium-90 Treatment of Hepatic Tumors Using Dynamic Contrast Enhanced MRI with Quantitative Perfusion Processing","display_name":"Prediction of Lung Shunt Fraction for Yttrium-90 Treatment of Hepatic Tumors Using Dynamic Contrast Enhanced MRI with Quantitative Perfusion Processing","publication_year":2022,"publication_date":"2022-11-03","ids":{"openalex":"https://openalex.org/W4309091237","doi":"https://doi.org/10.3390/tomography8060224","pmid":"https://pubmed.ncbi.nlm.nih.gov/36412683"},"language":"en","primary_location":{"id":"doi:10.3390/tomography8060224","doi":"https://doi.org/10.3390/tomography8060224","is_oa":true,"landing_page_url":"https://doi.org/10.3390/tomography8060224","pdf_url":"https://www.mdpi.com/2379-139X/8/6/224/pdf?version=1667457481","source":{"id":"https://openalex.org/S4210172093","display_name":"Tomography","issn_l":"2379-1381","issn":["2379-1381","2379-139X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tomography","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2379-139X/8/6/224/pdf?version=1667457481","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103072858","display_name":"Qihao Zhang","orcid":"https://orcid.org/0000-0002-8054-5849","observed_orcids":["https://orcid.org/0000-0002-8054-5849","https://orcid.org/0009-0003-1855-7747"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qihao Zhang","raw_affiliation_strings":["Department of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081476023","display_name":"Kyungmouk Steve Lee","orcid":"https://orcid.org/0000-0003-1975-4964","observed_orcids":["https://orcid.org/0000-0003-1975-4964"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyungmouk Steve Lee","raw_affiliation_strings":["Radiology, Weill Cornell Medicine, New York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology, Weill Cornell Medicine, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060114341","display_name":"Adam D. Talenfeld","orcid":"https://orcid.org/0000-0002-3029-720X","observed_orcids":["https://orcid.org/0000-0002-3029-720X"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam D. Talenfeld","raw_affiliation_strings":["Radiology, Weill Cornell Medicine, New York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology, Weill Cornell Medicine, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090143609","display_name":"Pascal Spincemaille","orcid":"https://orcid.org/0000-0002-8821-1341","observed_orcids":["https://orcid.org/0000-0002-8821-1341"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pascal Spincemaille","raw_affiliation_strings":["Radiology, Weill Cornell Medicine, New York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology, Weill Cornell Medicine, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037258527","display_name":"Martin R. Prince","orcid":"https://orcid.org/0000-0002-9883-0584","observed_orcids":["https://orcid.org/0000-0002-9883-0584"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin R. Prince","raw_affiliation_strings":["Radiology, Weill Cornell Medicine, New York, NY 10065, USA"],"raw_orcid":"https://orcid.org/0000-0002-9883-0584","affiliations":[{"raw_affiliation_string":"Radiology, Weill Cornell Medicine, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100765501","display_name":"Yi Wang","orcid":"https://orcid.org/0000-0003-1404-8526","observed_orcids":["https://orcid.org/0000-0003-1404-8526"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yi Wang","raw_affiliation_strings":["Radiology, Weill Cornell Medicine, New York, NY 10065, USA"],"raw_orcid":"https://orcid.org/0000-0003-1404-8526","affiliations":[{"raw_affiliation_string":"Radiology, Weill Cornell Medicine, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100765501"],"corresponding_institution_ids":["https://openalex.org/I4387153466"],"apc_list":{"value":1800,"currency":"CHF","value_usd":1885},"apc_paid":{"value":1800,"currency":"CHF","value_usd":1885},"fwci":1.1602,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.78518964,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":98},"biblio":{"volume":"8","issue":"6","first_page":"2687","last_page":"2697"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.44339999556541443,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.44339999556541443,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.33180001378059387,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.13989999890327454,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lung-shunt-fraction","display_name":"lung shunt fraction","score":0.9580000042915344},{"id":"https://openalex.org/keywords/yttrium-90-radioembolization","display_name":"yttrium-90 radioembolization","score":0.8889999985694885},{"id":"https://openalex.org/keywords/liver-tumors","display_name":"liver tumors","score":0.8199999928474426},{"id":"https://openalex.org/keywords/dynamic-contrast-enhanced-mri","display_name":"dynamic contrast-enhanced MRI","score":0.8190000057220459},{"id":"https://openalex.org/keywords/perfusion-quantification","display_name":"perfusion quantification","score":0.7289999723434448},{"id":"https://openalex.org/keywords/non-invasive-prediction","display_name":"non-invasive prediction","score":0.6589999794960022},{"id":"https://openalex.org/keywords/tumor-vascular-permeability","display_name":"tumor vascular permeability","score":0.3709999918937683}],"concepts":[{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.5825533866882324},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.5793081521987915},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.543275773525238},{"id":"https://openalex.org/C41727105","wikidata":"https://www.wikidata.org/wiki/Q17009718","display_name":"Dynamic contrast-enhanced MRI","level":3,"score":0.5363242626190186},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.4519668221473694},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.44596803188323975},{"id":"https://openalex.org/C2994142346","wikidata":"https://www.wikidata.org/wiki/Q353268","display_name":"Dynamic contrast","level":3,"score":0.4184775948524475},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3450930118560791},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.329683780670166}],"mesh":[{"descriptor_ui":"D006499","descriptor_name":"Hepatic Artery","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006499","descriptor_name":"Hepatic Artery","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006499","descriptor_name":"Hepatic Artery","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010477","descriptor_name":"Perfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010477","descriptor_name":"Perfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010477","descriptor_name":"Perfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015021","descriptor_name":"Yttrium Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3390/tomography8060224","doi":"https://doi.org/10.3390/tomography8060224","is_oa":true,"landing_page_url":"https://doi.org/10.3390/tomography8060224","pdf_url":"https://www.mdpi.com/2379-139X/8/6/224/pdf?version=1667457481","source":{"id":"https://openalex.org/S4210172093","display_name":"Tomography","issn_l":"2379-1381","issn":["2379-1381","2379-139X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tomography","raw_type":"journal-article"},{"id":"pmid:36412683","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36412683","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tomography (Ann Arbor, Mich.)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9680251","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9680251","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tomography","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:6b5f3ebac22a4ea1b3a7d580a7e60424","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6b5f3ebac22a4ea1b3a7d580a7e60424","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tomography, Vol 8, Iss 6, Pp 2687-2697 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/tomography8060224","doi":"https://doi.org/10.3390/tomography8060224","is_oa":true,"landing_page_url":"https://doi.org/10.3390/tomography8060224","pdf_url":"https://www.mdpi.com/2379-139X/8/6/224/pdf?version=1667457481","source":{"id":"https://openalex.org/S4210172093","display_name":"Tomography","issn_l":"2379-1381","issn":["2379-1381","2379-139X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tomography","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8100000023841858}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4309091237.pdf","grobid_xml":"https://content.openalex.org/works/W4309091237.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W1961519259","https://openalex.org/W1967735756","https://openalex.org/W1972656626","https://openalex.org/W1984869178","https://openalex.org/W2008457375","https://openalex.org/W2008979634","https://openalex.org/W2024247808","https://openalex.org/W2025725701","https://openalex.org/W2034411486","https://openalex.org/W2039385259","https://openalex.org/W2040530812","https://openalex.org/W2042098439","https://openalex.org/W2055447603","https://openalex.org/W2056450893","https://openalex.org/W2066037527","https://openalex.org/W2077862300","https://openalex.org/W2082602973","https://openalex.org/W2084035327","https://openalex.org/W2091422377","https://openalex.org/W2091650440","https://openalex.org/W2096029667","https://openalex.org/W2103545475","https://openalex.org/W2103849118","https://openalex.org/W2114355982","https://openalex.org/W2123093983","https://openalex.org/W2141640262","https://openalex.org/W2148464313","https://openalex.org/W2149138557","https://openalex.org/W2157980628","https://openalex.org/W2235703329","https://openalex.org/W2280732323","https://openalex.org/W2296193683","https://openalex.org/W2322564098","https://openalex.org/W2343563442","https://openalex.org/W2346693478","https://openalex.org/W2520669866","https://openalex.org/W2746245149","https://openalex.org/W2772445760","https://openalex.org/W2774659630","https://openalex.org/W2808343263","https://openalex.org/W2917537324","https://openalex.org/W2939547669","https://openalex.org/W2975732255","https://openalex.org/W3003504374","https://openalex.org/W3089394501","https://openalex.org/W3098349601","https://openalex.org/W3120026487","https://openalex.org/W3158944344","https://openalex.org/W3203921329","https://openalex.org/W3204052113","https://openalex.org/W3212344632","https://openalex.org/W4248580358","https://openalex.org/W6660670818","https://openalex.org/W6689366530","https://openalex.org/W6705260092","https://openalex.org/W6827387910"],"related_works":["https://openalex.org/W2017058200","https://openalex.org/W2299779964","https://openalex.org/W2419198331","https://openalex.org/W2117889023","https://openalex.org/W2144450524","https://openalex.org/W2317772852","https://openalex.org/W4391191811","https://openalex.org/W2377517991","https://openalex.org/W2347317511","https://openalex.org/W2996905865"],"abstract_inverted_index":{"There":[0],"is":[1,231],"no":[2,136],"noninvasive":[3,26],"method":[4],"to":[5,22,41],"estimate":[6],"lung":[7],"shunting":[8],"fraction":[9],"(LSF)":[10],"in":[11,45],"patients":[12],"with":[13,54,122,141,236],"liver":[14,47],"tumors":[15],"undergoing":[16],"Yttrium-90":[17],"(Y90)":[18],"therapy.":[19],"We":[20],"propose":[21],"predict":[23],"LSF":[24,79,118,153,156,212,215,230],"from":[25,233],"dynamic":[27],"contrast":[28],"enhanced":[29],"(DCE)":[30],"MRI":[31,44,235],"using":[32,74],"perfusion":[33,36],"quantification.":[34],"Two":[35],"quantification":[37],"methods":[38],"were":[39],"used":[40],"process":[42],"DCE":[43,234],"25":[46],"tumor":[48,144],"patients:":[49],"Kety\u2019s":[50,142,178],"tracer":[51],"kinetic":[52],"modeling":[53],"a":[55,100,107,160],"delay-fitted":[56],"global":[57],"arterial":[58,92],"input":[59],"function":[60],"(AIF)":[61],"and":[62,106,135,148,154,177,190,213,223],"quantitative":[63],"transport":[64,72],"mapping":[65],"(QTM)":[66],"based":[67],"on":[68,82],"the":[69,151,205],"inversion":[70],"of":[71,229],"equation":[73],"spatial":[75],"deconvolution":[76],"without":[77],"AIF.":[78],"was":[80,97,119,139,159,216],"measured":[81],"SPECT":[83],"following":[84],"Tc-99m":[85],"macroaggregated":[86],"albumin":[87],"(MAA)":[88],"administration":[89],"via":[90],"hepatic":[91],"catheter.":[93],"The":[94,202],"patient":[95,116,146],"cohort":[96],"partitioned":[98],"into":[99],"low-risk":[101],"group":[102,109],"(LSF":[103,110],"\u2264":[104],"10%)":[105],"high-risk":[108],">":[111],"10%).":[112],"Results:":[113],"In":[114],"this":[115],"cohort,":[117],"positively":[120],"correlated":[121],"QTM":[123,164,237],"velocity":[124,238],"|u|":[125,165],"(r":[126],"=":[127,130,133,175,188,200],"0.61,":[128],"F":[129],"14.0363,":[131],"p":[132,174,187,199],"0.0021),":[134],"significant":[137,161],"correlation":[138],"observed":[140],"parameters,":[143],"volume,":[145],"age":[147],"gender.":[149],"Between":[150],"low":[152,211],"high":[155,214],"groups,":[157],"there":[158],"difference":[162],"for":[163,208,218,221,225],"(0.0760":[166],"\u00b1":[167,171,181,185,193,197],"0.0440":[168],"vs.":[169,195],"0.1822":[170],"0.1225":[172],"mm/s,":[173],"0.0011),":[176],"Ktrans":[179],"(0.0401":[180],"0.0360":[182],"vs":[183],"0.1198":[184],"0.3048,":[186],"0.0471)":[189],"Ve":[191,222],"(0.0900":[192],"0.0307":[194],"0.1495":[196],"0.0485,":[198],"0.0114).":[201],"area":[203],"under":[204],"curve":[206],"(AUC)":[207],"distinguishing":[209],"between":[210],"0.87":[217],"|u|,":[219],"0.80":[220],"0.74":[224],"Ktrans.":[226],"Noninvasive":[227],"prediction":[228],"feasible":[232],"postprocessing.":[239]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4}],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2025-10-10T00:00:00"}