{"id":"https://openalex.org/W4308697121","doi":"https://doi.org/10.3390/ijms232213822","title":"miRNAs in Regulation of Tumor Microenvironment, Chemotherapy Resistance, Immunotherapy Modulation and miRNA Therapeutics in Cancer","display_name":"miRNAs in Regulation of Tumor Microenvironment, Chemotherapy Resistance, Immunotherapy Modulation and miRNA Therapeutics in Cancer","publication_year":2022,"publication_date":"2022-11-10","ids":{"openalex":"https://openalex.org/W4308697121","doi":"https://doi.org/10.3390/ijms232213822","pmid":"https://pubmed.ncbi.nlm.nih.gov/36430305","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9699074"},"language":"en","primary_location":{"id":"doi:10.3390/ijms232213822","doi":"https://doi.org/10.3390/ijms232213822","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms232213822","pdf_url":"https://www.mdpi.com/1422-0067/23/22/13822/pdf?version=1668066732","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1422-0067/23/22/13822/pdf?version=1668066732","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026008292","display_name":"Kousain Kousar","orcid":"https://orcid.org/0000-0002-0325-0131","observed_orcids":["https://orcid.org/0000-0002-0325-0131"]},"institutions":[{"id":"https://openalex.org/I929597975","display_name":"National University of Sciences and Technology","ror":"https://ror.org/03w2j5y17","country_code":"PK","type":"education","lineage":["https://openalex.org/I929597975"]}],"countries":["PK"],"is_corresponding":true,"raw_author_name":"Kousain Kousar","raw_affiliation_strings":["Industrial Biotechnology, Atta Ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Industrial Biotechnology, Atta Ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan","institution_ids":["https://openalex.org/I929597975"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tahir Ahmad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I929597975","display_name":"National University of Sciences and Technology","ror":"https://ror.org/03w2j5y17","country_code":"PK","type":"education","lineage":["https://openalex.org/I929597975"]}],"countries":["PK"],"is_corresponding":true,"raw_author_name":"Tahir Ahmad","raw_affiliation_strings":["Industrial Biotechnology, Atta Ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Industrial Biotechnology, Atta Ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan","institution_ids":["https://openalex.org/I929597975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064214529","display_name":"Maisa Siddiq Abduh","orcid":"https://orcid.org/0000-0002-7231-3386","observed_orcids":["https://orcid.org/0000-0002-7231-3386"]},"institutions":[{"id":"https://openalex.org/I185163786","display_name":"King Abdulaziz University","ror":"https://ror.org/02ma4wv74","country_code":"SA","type":"education","lineage":["https://openalex.org/I185163786"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Maisa S. Abduh","raw_affiliation_strings":["Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia"],"raw_orcid":"https://orcid.org/0000-0002-7231-3386","affiliations":[{"raw_affiliation_string":"Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia","institution_ids":["https://openalex.org/I185163786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014314988","display_name":"Balquees Kanwal","orcid":"https://orcid.org/0000-0001-5464-3923","observed_orcids":["https://orcid.org/0000-0001-5464-3923"]},"institutions":[{"id":"https://openalex.org/I929597975","display_name":"National University of Sciences and Technology","ror":"https://ror.org/03w2j5y17","country_code":"PK","type":"education","lineage":["https://openalex.org/I929597975"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Balquees Kanwal","raw_affiliation_strings":["Healthcare Biotechnology, Atta Ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Healthcare Biotechnology, Atta Ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan","institution_ids":["https://openalex.org/I929597975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068759050","display_name":"Syeda Saba Shah","orcid":"https://orcid.org/0009-0004-2218-6421","observed_orcids":["https://orcid.org/0009-0004-2218-6421"]},"institutions":[{"id":"https://openalex.org/I929597975","display_name":"National University of Sciences and Technology","ror":"https://ror.org/03w2j5y17","country_code":"PK","type":"education","lineage":["https://openalex.org/I929597975"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Syeda Saba Shah","raw_affiliation_strings":["Healthcare Biotechnology, Atta Ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Healthcare Biotechnology, Atta Ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan","institution_ids":["https://openalex.org/I929597975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061077446","display_name":"Faiza Naseer","orcid":"https://orcid.org/0000-0002-4146-3146","observed_orcids":["https://orcid.org/0000-0002-4146-3146"]},"institutions":[{"id":"https://openalex.org/I179531654","display_name":"Shifa Tameer-e-Millat University","ror":"https://ror.org/021p6rb08","country_code":"PK","type":"education","lineage":["https://openalex.org/I179531654"]},{"id":"https://openalex.org/I929597975","display_name":"National University of Sciences and Technology","ror":"https://ror.org/03w2j5y17","country_code":"PK","type":"education","lineage":["https://openalex.org/I929597975"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Faiza Naseer","raw_affiliation_strings":["Industrial Biotechnology, Atta Ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan","Shifa College of Pharmaceutical Sciences, Shifa Tameer e Millat University, Islamabad 44000, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Industrial Biotechnology, Atta Ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad 44000, Pakistan","institution_ids":["https://openalex.org/I929597975"]},{"raw_affiliation_string":"Shifa College of Pharmaceutical Sciences, Shifa Tameer e Millat University, Islamabad 44000, Pakistan","institution_ids":["https://openalex.org/I179531654"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032703069","display_name":"Sadia Anjum","orcid":"https://orcid.org/0000-0001-9678-7861","observed_orcids":["https://orcid.org/0000-0001-9678-7861"]},"institutions":[{"id":"https://openalex.org/I4210088963","display_name":"University of Ha'il","ror":"https://ror.org/013w98a82","country_code":"SA","type":"education","lineage":["https://openalex.org/I4210088963"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Sadia Anjum","raw_affiliation_strings":["Department of Biology, University of Hail, Hail 81442, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Hail, Hail 81442, Saudi Arabia","institution_ids":["https://openalex.org/I4210088963"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5026008292"],"corresponding_institution_ids":["https://openalex.org/I929597975"],"apc_list":{"value":2300,"currency":"CHF","value_usd":2408},"apc_paid":{"value":2300,"currency":"CHF","value_usd":2408},"fwci":1.149,"has_fulltext":true,"cited_by_count":60,"citation_normalized_percentile":{"value":0.80100056,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"23","issue":"22","first_page":"13822","last_page":"13822"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.9919999837875366},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.9950000047683716},{"id":"https://openalex.org/keywords/chemoresistance","display_name":"chemoresistance","score":0.9620000123977661},{"id":"https://openalex.org/keywords/immunotherapy","display_name":"immunotherapy","score":0.7749999761581421},{"id":"https://openalex.org/keywords/immune-evasion","display_name":"immune evasion","score":0.8489999771118164},{"id":"https://openalex.org/keywords/tumor-associated-macrophages","display_name":"tumor-associated macrophages","score":0.8659999966621399},{"id":"https://openalex.org/keywords/regulatory-t-cells","display_name":"regulatory T cells","score":0.8479999899864197},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.9620000123977661},{"id":"https://openalex.org/keywords/t-helper-cells","display_name":"T helper cells","score":0.6499999761581421},{"id":"https://openalex.org/keywords/tumor-suppressor-microrna","display_name":"tumor suppressor microRNA","score":0.656000018119812},{"id":"https://openalex.org/keywords/oncogenic-microrna","display_name":"oncogenic microRNA","score":0.9300000071525574},{"id":"https://openalex.org/keywords/checkpoint-blockade","display_name":"checkpoint blockade","score":0.5929999947547913},{"id":"https://openalex.org/keywords/adoptive-t-cell-therapy","display_name":"adoptive T cell therapy","score":0.9900000095367432},{"id":"https://openalex.org/keywords/oncolytic-virotherapy","display_name":"oncolytic virotherapy","score":0.9950000047683716},{"id":"https://openalex.org/keywords/microrna-therapy","display_name":"miRNA-based therapy","score":0.8930000066757202},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.703000009059906},{"id":"https://openalex.org/keywords/chronic-inflammation","display_name":"chronic inflammation","score":0.8370000123977661}],"concepts":[{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.7434829473495483},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6547285318374634},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.6411371231079102},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5946574807167053},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5725827217102051},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.513647735118866},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5074593424797058},{"id":"https://openalex.org/C82210918","wikidata":"https://www.wikidata.org/wiki/Q1560099","display_name":"Oncolytic virus","level":3,"score":0.44537994265556335},{"id":"https://openalex.org/C2780674031","wikidata":"https://www.wikidata.org/wiki/Q2012719","display_name":"Cancer immunotherapy","level":4,"score":0.44143927097320557},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3982962965965271},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.38935989141464233},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08421620726585388},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007155","descriptor_name":"Immunologic Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3390/ijms232213822","doi":"https://doi.org/10.3390/ijms232213822","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms232213822","pdf_url":"https://www.mdpi.com/1422-0067/23/22/13822/pdf?version=1668066732","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},{"id":"pmid:36430305","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36430305","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of molecular sciences","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9699074","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9699074/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Mol Sci","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:d304ff48bb2f49bebc0edf0ac3757f3f","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/d304ff48bb2f49bebc0edf0ac3757f3f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Molecular Sciences, Vol 23, Iss 13822, p 13822 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/ijms232213822","doi":"https://doi.org/10.3390/ijms232213822","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms232213822","pdf_url":"https://www.mdpi.com/1422-0067/23/22/13822/pdf?version=1668066732","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9922999739646912,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322322","display_name":"King Abdulaziz University","ror":"https://ror.org/02ma4wv74"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4308697121.pdf","grobid_xml":"https://content.openalex.org/works/W4308697121.grobid-xml"},"referenced_works_count":89,"referenced_works":["https://openalex.org/W1966059799","https://openalex.org/W2004793776","https://openalex.org/W2062380899","https://openalex.org/W2076600424","https://openalex.org/W2077981848","https://openalex.org/W2160153675","https://openalex.org/W2214960086","https://openalex.org/W2328650364","https://openalex.org/W2330289614","https://openalex.org/W2469459870","https://openalex.org/W2505716482","https://openalex.org/W2559922077","https://openalex.org/W2562367675","https://openalex.org/W2592021046","https://openalex.org/W2605111841","https://openalex.org/W2605437897","https://openalex.org/W2732104535","https://openalex.org/W2734323448","https://openalex.org/W2744657869","https://openalex.org/W2755550738","https://openalex.org/W2770878260","https://openalex.org/W2773279071","https://openalex.org/W2793675794","https://openalex.org/W2801932471","https://openalex.org/W2806546829","https://openalex.org/W2806593469","https://openalex.org/W2811212358","https://openalex.org/W2811453807","https://openalex.org/W2886810945","https://openalex.org/W2891691090","https://openalex.org/W2896672574","https://openalex.org/W2900533499","https://openalex.org/W2906260974","https://openalex.org/W2906335862","https://openalex.org/W2911775745","https://openalex.org/W2943702218","https://openalex.org/W2946971144","https://openalex.org/W2957883742","https://openalex.org/W2968702228","https://openalex.org/W2970033143","https://openalex.org/W2970661365","https://openalex.org/W2971629072","https://openalex.org/W2972973587","https://openalex.org/W2974034981","https://openalex.org/W2982350172","https://openalex.org/W2990438875","https://openalex.org/W2995326687","https://openalex.org/W2995416048","https://openalex.org/W2996236370","https://openalex.org/W3010228870","https://openalex.org/W3010881000","https://openalex.org/W3016565860","https://openalex.org/W3047523306","https://openalex.org/W3048404543","https://openalex.org/W3081386532","https://openalex.org/W3090466759","https://openalex.org/W3105938835","https://openalex.org/W3111745408","https://openalex.org/W3120278224","https://openalex.org/W3151646265","https://openalex.org/W3195231616","https://openalex.org/W3199530227","https://openalex.org/W3199732256","https://openalex.org/W3201558704","https://openalex.org/W3203608704","https://openalex.org/W3214150948","https://openalex.org/W3215594691","https://openalex.org/W3217771471","https://openalex.org/W4200458196","https://openalex.org/W4205123568","https://openalex.org/W4210379772","https://openalex.org/W4214812612","https://openalex.org/W4220736375","https://openalex.org/W4221004204","https://openalex.org/W4223538657","https://openalex.org/W4224037815","https://openalex.org/W4224250839","https://openalex.org/W4281254006","https://openalex.org/W4282829530","https://openalex.org/W4285264344","https://openalex.org/W4286599437","https://openalex.org/W4292246694","https://openalex.org/W4301394290","https://openalex.org/W4307374344","https://openalex.org/W6749271757","https://openalex.org/W6758101118","https://openalex.org/W6761816707","https://openalex.org/W6765291831","https://openalex.org/W6767916610"],"related_works":["https://openalex.org/W4411823592","https://openalex.org/W4285275840","https://openalex.org/W7204962706","https://openalex.org/W7115178945","https://openalex.org/W4309093325","https://openalex.org/W7165934618","https://openalex.org/W4200497833","https://openalex.org/W3156958341","https://openalex.org/W4405335554","https://openalex.org/W3162299961"],"abstract_inverted_index":{"miRNAs":[0,37,80,136],"are":[1,26],"20-22":[2],"long":[3],"nucleotide":[4],"non-coding":[5],"ribonucleic":[6],"acid":[7],"molecules":[8,131],"critical":[9],"to":[10,116],"the":[11,19,87,109,139],"modulation":[12],"of":[13,21,65,89,108,111,128,141],"molecular":[14],"pathways.":[15],"Immune":[16],"evasion":[17],"and":[18,34,54,63,77,100,137],"establishment":[20],"a":[22,82],"suitable":[23],"tumor":[24,32,142],"microenvironment":[25],"two":[27,40],"major":[28],"contributors":[29],"that":[30,74,132],"support":[31,38],"invasion":[33],"metastasis.":[35],"Tumorigenic":[36],"these":[39],"hallmarks":[41],"by":[42],"desensitizing":[43],"important":[44],"tumor-sensitive":[45],"regulatory":[46],"cells":[47,57,67],"such":[48],"as":[49,125],"dendritic":[50],"cells,":[51,70],"M1":[52],"macrophages,":[53],"T":[55,97],"helper":[56],"towards":[58],"tumors":[59],"while":[60],"supporting":[61],"infiltration":[62],"proliferation":[64],"immune":[66],"like":[68,92],"Treg":[69],"tumor-associated":[71],"M2":[72],"macrophages":[73],"promote":[75,138],"self-tolerance":[76],"chronic":[78],"inflammation.":[79],"have":[81,123],"significant":[83],"role":[84,110],"in":[85,103],"enhancing":[86],"efficacies":[88],"immunotherapy":[90],"treatments":[91],"checkpoint":[93],"blockade":[94],"therapy,":[95,99],"adoptive":[96],"cell":[98],"oncolytic":[101],"virotherapy":[102],"cancer.":[104],"A":[105],"clear":[106],"understanding":[107],"miRNA":[112,121],"can":[113,133],"help":[114],"scientists":[115],"formulate":[117],"better-targeted":[118],"treatment":[119],"modalities.":[120],"therapeutics":[122],"emerged":[124],"diverse":[126],"class":[127],"nucleic":[129],"acid-based":[130],"suppress":[134],"oncogenic":[135],"expression":[140],"suppressor":[143],"miRNAs.":[144]},"counts_by_year":[{"year":2026,"cited_by_count":17},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":14},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-11-14T00:00:00"}