{"id":"https://openalex.org/W4308596291","doi":"https://doi.org/10.9734/jpri/2022/v34i52b7219","title":"A Systematic Review and Meta-analysis of Efficacy of Carbapenems versus Other Best Available Antibiotics in the Management of Patients with Urinary Tract Infections","display_name":"A Systematic Review and Meta-analysis of Efficacy of Carbapenems versus Other Best Available Antibiotics in the Management of Patients with Urinary Tract Infections","publication_year":2022,"publication_date":"2022-11-08","ids":{"openalex":"https://openalex.org/W4308596291","doi":"https://doi.org/10.9734/jpri/2022/v34i52b7219"},"language":"en","primary_location":{"id":"doi:10.9734/jpri/2022/v34i52b7219","doi":"https://doi.org/10.9734/jpri/2022/v34i52b7219","is_oa":true,"landing_page_url":"https://doi.org/10.9734/jpri/2022/v34i52b7219","pdf_url":"https://journaljpri.com/index.php/JPRI/article/download/7219/14441","source":{"id":"https://openalex.org/S4210206555","display_name":"Journal of Pharmaceutical Research International","issn_l":"2231-2919","issn":["2231-2919","2456-9119"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20"],"host_organization":"https://openalex.org/P4310320855","host_organization_name":"Sciencedomain International","host_organization_lineage":["https://openalex.org/P4310320855"],"host_organization_lineage_names":["Sciencedomain International"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Research International","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://journaljpri.com/index.php/JPRI/article/download/7219/14441","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002242466","display_name":"Ruoa Faisal Albunayyan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130698","display_name":"Security Forces Hospital","ror":"https://ror.org/035n3nf68","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210130698"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Ruoa Albunayyan","raw_affiliation_strings":["Pharmacy Department, Security Forces Hospital (SFH), Mecca, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacy Department, Security Forces Hospital (SFH), Mecca, Saudi Arabia","institution_ids":["https://openalex.org/I4210130698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090919453","display_name":"Bushra Alqurashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130698","display_name":"Security Forces Hospital","ror":"https://ror.org/035n3nf68","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210130698"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Bushra Alqurashi","raw_affiliation_strings":["Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia","institution_ids":["https://openalex.org/I4210130698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113130365","display_name":"Yasser Alharbi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130698","display_name":"Security Forces Hospital","ror":"https://ror.org/035n3nf68","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210130698"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Yasser Alharbi","raw_affiliation_strings":["Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia","institution_ids":["https://openalex.org/I4210130698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060643196","display_name":"Aisha Alshaer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130698","display_name":"Security Forces Hospital","ror":"https://ror.org/035n3nf68","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210130698"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Aisha Alshaer","raw_affiliation_strings":["Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia","institution_ids":["https://openalex.org/I4210130698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080990452","display_name":"Jomana Alsudais","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130698","display_name":"Security Forces Hospital","ror":"https://ror.org/035n3nf68","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210130698"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Jomana Alsudais","raw_affiliation_strings":["Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia","institution_ids":["https://openalex.org/I4210130698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081662341","display_name":"Ahad Alghthami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130698","display_name":"Security Forces Hospital","ror":"https://ror.org/035n3nf68","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210130698"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Ahad Alghthami","raw_affiliation_strings":["Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia","institution_ids":["https://openalex.org/I4210130698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052390325","display_name":"Jumana Alsharif","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130698","display_name":"Security Forces Hospital","ror":"https://ror.org/035n3nf68","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210130698"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Jumana Alsharif","raw_affiliation_strings":["Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia","institution_ids":["https://openalex.org/I4210130698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068834704","display_name":"Lujain Alabbas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130698","display_name":"Security Forces Hospital","ror":"https://ror.org/035n3nf68","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210130698"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Lujain Alabbas","raw_affiliation_strings":["Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia","institution_ids":["https://openalex.org/I4210130698"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065767227","display_name":"Rehab Almehmadi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130698","display_name":"Security Forces Hospital","ror":"https://ror.org/035n3nf68","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210130698"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Rehab Almehmadi","raw_affiliation_strings":["Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacy Department, Security Forces Hospital (SFH), College of Pharmacy, Mecca,  Saudi Arabia","institution_ids":["https://openalex.org/I4210130698"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210130698"],"apc_list":null,"apc_paid":null,"fwci":0.1212,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.15903414,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":"34","issue":"52B","first_page":"27","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11232","display_name":"Urinary Tract Infections Management","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11232","display_name":"Urinary Tract Infections Management","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbapenems","display_name":"carbapenems","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pyelonephritis","display_name":"pyelonephritis","score":0.8790000081062317},{"id":"https://openalex.org/keywords/complicated-urinary-tract-infection","display_name":"complicated urinary tract infection","score":0.9490000009536743},{"id":"https://openalex.org/keywords/piperacillin-tazobactam","display_name":"piperacillin-tazobactam","score":0.9419999718666077},{"id":"https://openalex.org/keywords/meropenem","display_name":"meropenem","score":0.847000002861023},{"id":"https://openalex.org/keywords/meropenem-vaborbactam","display_name":"meropenem-vaborbactam","score":0.8790000081062317},{"id":"https://openalex.org/keywords/biapenem","display_name":"biapenem","score":0.7540000081062317},{"id":"https://openalex.org/keywords/doripenem","display_name":"doripenem","score":0.9869999885559082},{"id":"https://openalex.org/keywords/ertapenem","display_name":"ertapenem","score":0.9990000128746033},{"id":"https://openalex.org/keywords/extended-spectrum-beta-lactamase","display_name":"extended-spectrum beta-lactamase","score":0.9129999876022339},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.7049999833106995},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.6980000138282776},{"id":"https://openalex.org/keywords/clinical-failure","display_name":"clinical failure","score":0.6650000214576721}],"concepts":[{"id":"https://openalex.org/C2777821550","wikidata":"https://www.wikidata.org/wiki/Q411552","display_name":"Doripenem","level":5,"score":0.8964192867279053},{"id":"https://openalex.org/C2778368673","wikidata":"https://www.wikidata.org/wiki/Q553220","display_name":"Ertapenem","level":5,"score":0.8227112293243408},{"id":"https://openalex.org/C2779375183","wikidata":"https://www.wikidata.org/wiki/Q421670","display_name":"Meropenem","level":4,"score":0.81464022397995},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7394822835922241},{"id":"https://openalex.org/C2778193466","wikidata":"https://www.wikidata.org/wiki/Q423787","display_name":"Piperacillin","level":4,"score":0.7292040586471558},{"id":"https://openalex.org/C2776685102","wikidata":"https://www.wikidata.org/wiki/Q410897","display_name":"Carbapenem","level":3,"score":0.6708972454071045},{"id":"https://openalex.org/C2778266534","wikidata":"https://www.wikidata.org/wiki/Q423376","display_name":"Tazobactam","level":5,"score":0.652423083782196},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.6148005723953247},{"id":"https://openalex.org/C2777858937","wikidata":"https://www.wikidata.org/wiki/Q423376","display_name":"Piperacillin/tazobactam","level":5,"score":0.5660485029220581},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.5055246353149414},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5027332305908203},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4985682964324951},{"id":"https://openalex.org/C64778159","wikidata":"https://www.wikidata.org/wiki/Q271021","display_name":"Cephalosporin","level":3,"score":0.4452308416366577},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.43003469705581665},{"id":"https://openalex.org/C2779631663","wikidata":"https://www.wikidata.org/wiki/Q425152","display_name":"Imipenem","level":4,"score":0.31609728932380676},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.2822578251361847},{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.2301829755306244},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.22983723878860474},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09417226910591125},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.07107651233673096},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.9734/jpri/2022/v34i52b7219","doi":"https://doi.org/10.9734/jpri/2022/v34i52b7219","is_oa":true,"landing_page_url":"https://doi.org/10.9734/jpri/2022/v34i52b7219","pdf_url":"https://journaljpri.com/index.php/JPRI/article/download/7219/14441","source":{"id":"https://openalex.org/S4210206555","display_name":"Journal of Pharmaceutical Research International","issn_l":"2231-2919","issn":["2231-2919","2456-9119"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20"],"host_organization":"https://openalex.org/P4310320855","host_organization_name":"Sciencedomain International","host_organization_lineage":["https://openalex.org/P4310320855"],"host_organization_lineage_names":["Sciencedomain International"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Research International","raw_type":"journal-article"},{"id":"pmh:oai:HAL:hal-05213404v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-05213404","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Pharmaceutical Research International, 2022, 34 (52B), pp.27-37","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.9734/jpri/2022/v34i52b7219","doi":"https://doi.org/10.9734/jpri/2022/v34i52b7219","is_oa":true,"landing_page_url":"https://doi.org/10.9734/jpri/2022/v34i52b7219","pdf_url":"https://journaljpri.com/index.php/JPRI/article/download/7219/14441","source":{"id":"https://openalex.org/S4210206555","display_name":"Journal of Pharmaceutical Research International","issn_l":"2231-2919","issn":["2231-2919","2456-9119"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20"],"host_organization":"https://openalex.org/P4310320855","host_organization_name":"Sciencedomain International","host_organization_lineage":["https://openalex.org/P4310320855"],"host_organization_lineage_names":["Sciencedomain International"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmaceutical Research International","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4308596291.pdf","grobid_xml":"https://content.openalex.org/works/W4308596291.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W106328305","https://openalex.org/W600496258","https://openalex.org/W1970243973","https://openalex.org/W1972079818","https://openalex.org/W2009574631","https://openalex.org/W2013188208","https://openalex.org/W2017585134","https://openalex.org/W2031240692","https://openalex.org/W2037002909","https://openalex.org/W2044612684","https://openalex.org/W2068407882","https://openalex.org/W2090889747","https://openalex.org/W2097341466","https://openalex.org/W2101568459","https://openalex.org/W2106946222","https://openalex.org/W2169722890","https://openalex.org/W2236111090","https://openalex.org/W2261296125","https://openalex.org/W2318963346","https://openalex.org/W2565419026","https://openalex.org/W2971556577","https://openalex.org/W2980192927","https://openalex.org/W3002996511","https://openalex.org/W3037933356","https://openalex.org/W3048794793","https://openalex.org/W3081358183","https://openalex.org/W4206709280","https://openalex.org/W4388308668","https://openalex.org/W6808432448"],"related_works":["https://openalex.org/W4366742270","https://openalex.org/W3092071308","https://openalex.org/W3000585845","https://openalex.org/W4396640583","https://openalex.org/W2904660060","https://openalex.org/W4406503314","https://openalex.org/W2544831261","https://openalex.org/W4405138301","https://openalex.org/W4200552456","https://openalex.org/W4327693309"],"abstract_inverted_index":{"Introduction:":[0],"Carbapenems":[1,66,101,266],"are":[2,10,18,267],"found":[3],"in":[4,7,47,75,80,104],"high":[5],"concentrations":[6],"urine":[8],"and":[9,24,133,152,156,180,189,235,237,254],"mainly":[11],"eliminated":[12],"by":[13,31,147],"the":[14,19,48,63,70,76,98,105,120,148,167,222,241,259,261,271,274],"kidney.":[15],"Hence,":[16],"they":[17],"preferred":[20],"treatment":[21,106,168],"for":[22,52,55,238,273],"pyelonephritis":[23,79],"complicated":[25,56,170,277],"urinary":[26,109,278],"tract":[27,110,279],"infections":[28],"(cUTIs)":[29],"caused":[30],"extended-spectrum":[32],"\u03b2-lactamase":[33],"(ESBL)":[34],"producing":[35],"bacteria.":[36],"The":[37,172,203],"recent":[38],"emergence":[39],"of":[40,65,78,100,107,119,127,142,150,154,169,174,191,276],"bacterial":[41],"resistance":[42],"to":[43,50,61,92,184,208,258,270],"carbapenems":[44,192,207],"has":[45],"resulted":[46],"need":[49],"search":[51],"alternative":[53],"treatments":[54],"UTIs.":[57,84],"This":[58,161],"review":[59,88,162],"aims":[60],"evaluate":[62],"efficacy":[64],"versus":[67,102],"Piperacillin/tacobactam":[68,103],"(or":[69],"best":[71,212],"available":[72,213],"antibiotic":[73],"therapy)":[74],"management":[77,275],"patients":[81,129,175],"with":[82,138,228,247],"upper":[83,108],"Methods:":[85],"A":[86,114],"systematic":[87],"was":[89,116,145,226,245],"carried":[90,117],"out":[91,118],"compile":[93],"all":[94],"relevant":[95],"studies":[96,144,165,205,263],"on":[97,166],"use":[99],"infections,":[111],"namely":[112],"pyelonephritis.":[113,139,171],"meta-analysis":[115],"selected":[121],"studies,":[122],"including":[123,195],"clinical":[124,239],"trials":[125],"composed":[126],"adult":[128],"aged":[130],"between":[131,233,252],"18":[132],"80":[134],"years":[135],"old":[136],"diagnosed":[137],"Primary":[140],"screening":[141],"eligible":[143],"followed":[146],"removal":[149],"duplicates":[151],"exclusion":[153],"non-eligible":[155],"unavailable":[157],"full-text":[158],"trials.":[159],"Results:":[160],"included":[163,176,204,262],"four":[164],"number":[173],"per":[177],"study":[178],"varied":[179],"ranged":[181],"from":[182],"62":[183],"421":[185],"cases.":[186],"Different":[187],"types":[188],"regimes":[190],"were":[193],"used,":[194],"intravenous":[196],"Meropenem-Vaborbactam,":[197],"Meropenem,":[198],"Biapenem,":[199],"Doripenem,":[200],"or":[201,210],"Ertapenem.":[202],"compared":[206],"Piperacillin/tazobactam":[209],"other":[211],"therapies,":[214],"such":[215],"as":[216],"third-generation":[217],"cephalosporin.":[218],"For":[219],"microbial":[220],"failure,":[221,240],"overall":[223,242],"risk":[224,243],"ratio":[225,244],"0.95":[227],"a":[229,248],"confidence":[230,249],"interval":[231,250],"range":[232,251],"0.62":[234],"1.45,":[236],"0.86":[246],"0.51":[253],"1.45.":[255],"Conclusions:":[256],"According":[257],"meta-analysis,":[260],"showed":[264],"that":[265],"not":[268],"inferior":[269],"comparators":[272],"infections.":[280]},"counts_by_year":[{"year":2025,"cited_by_count":2}],"updated_date":"2026-10-25T09:29:13.331239","created_date":"2022-11-12T00:00:00"}