{"id":"https://openalex.org/W4308592425","doi":"https://doi.org/10.1117/1.jbo.27.11.116002","title":"Algorithms and instrumentation for rapid spatial frequency domain fluorescence diffuse optical imaging","display_name":"Algorithms and instrumentation for rapid spatial frequency domain fluorescence diffuse optical imaging","publication_year":2022,"publication_date":"2022-11-08","ids":{"openalex":"https://openalex.org/W4308592425","doi":"https://doi.org/10.1117/1.jbo.27.11.116002","pmid":"https://pubmed.ncbi.nlm.nih.gov/36348511","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9641268"},"language":"en","primary_location":{"id":"doi:10.1117/1.jbo.27.11.116002","doi":"https://doi.org/10.1117/1.jbo.27.11.116002","is_oa":true,"landing_page_url":"https://doi.org/10.1117/1.jbo.27.11.116002","pdf_url":"https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-27/issue-11/116002/Algorithms-and-instrumentation-for-rapid-spatial-frequency-domain-fluorescence-diffuse/10.1117/1.JBO.27.11.116002.pdf","source":{"id":"https://openalex.org/S117354312","display_name":"Journal of Biomedical Optics","issn_l":"1083-3668","issn":["1083-3668","1560-2281"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Optics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-27/issue-11/116002/Algorithms-and-instrumentation-for-rapid-spatial-frequency-domain-fluorescence-diffuse/10.1117/1.JBO.27.11.116002.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110152502","display_name":"Sang Hoon Chong","orcid":"https://orcid.org/0000-0002-6722-0812","observed_orcids":["https://orcid.org/0000-0002-6722-0812"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sang Hoon Chong","raw_affiliation_strings":["Univ. of Pennsylvania","University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States"],"raw_orcid":"https://orcid.org/0000-0002-6722-0812","affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020897629","display_name":"Vadim A. Markel","orcid":"https://orcid.org/0000-0002-9748-6865","observed_orcids":["https://orcid.org/0000-0002-9748-6865"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vadim A. Markel","raw_affiliation_strings":["Univ. of Pennsylvania","University of Pennsylvania, Department of Radiology, Philadelphia, Pennsylvania, United States"],"raw_orcid":"https://orcid.org/0000-0002-9748-6865","affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"University of Pennsylvania, Department of Radiology, Philadelphia, Pennsylvania, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090464228","display_name":"Ashwin B. Parthasarathy","orcid":"https://orcid.org/0000-0003-2024-3432","observed_orcids":["https://orcid.org/0000-0003-2024-3432"]},"institutions":[{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashwin B. Parthasarathy","raw_affiliation_strings":["Univ. of South Florida","University of South Florida, Department of Electrical Engineering, Tampa, Florida, United States"],"raw_orcid":"https://orcid.org/0000-0003-2024-3432","affiliations":[{"raw_affiliation_string":"Univ. of South Florida","institution_ids":["https://openalex.org/I2613432"]},{"raw_affiliation_string":"University of South Florida, Department of Electrical Engineering, Tampa, Florida, United States","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083769022","display_name":"Yi Hong Ong","orcid":"https://orcid.org/0000-0002-2826-1451","observed_orcids":["https://orcid.org/0000-0002-2826-1451"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yihong Ong","raw_affiliation_strings":["Univ. of Pennsylvania","University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States"],"raw_orcid":"https://orcid.org/0000-0002-2826-1451","affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044728429","display_name":"Kenneth Abramson","orcid":"https://orcid.org/0000-0002-0781-2648","observed_orcids":["https://orcid.org/0000-0002-0781-2648"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth Abramson","raw_affiliation_strings":["Univ. of Pennsylvania","University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007427427","display_name":"Frank A. Moscatelli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frank A. Moscatelli","raw_affiliation_strings":["New York University, Department of Physics, New York, United States","New York University, Department of Physics, New York, United States (United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University, Department of Physics, New York, United States","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York University, Department of Physics, New York, United States (United States)","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026866208","display_name":"Arjun G. Yodh","orcid":"https://orcid.org/0000-0003-4744-2706","observed_orcids":["https://orcid.org/0000-0003-4744-2706"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arjun G. Yodh","raw_affiliation_strings":["Univ. of Pennsylvania","University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States"],"raw_orcid":"https://orcid.org/0000-0003-4744-2706","affiliations":[{"raw_affiliation_string":"Univ. of Pennsylvania","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania, United States","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5110152502"],"corresponding_institution_ids":["https://openalex.org/I79576946"],"apc_list":{"value":1675,"currency":"USD","value_usd":1675},"apc_paid":{"value":1675,"currency":"USD","value_usd":1675},"fwci":0.2844,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.49971772,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"27","issue":"11","first_page":"1","last_page":"19"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/image-guided-surgery","display_name":"image-guided surgery","score":0.8500000238418579},{"id":"https://openalex.org/keywords/tumor-resection","display_name":"tumor resection","score":0.9810000061988831},{"id":"https://openalex.org/keywords/turbid-media","display_name":"turbid media","score":0.6019999980926514},{"id":"https://openalex.org/keywords/tissue-phantoms","display_name":"tissue phantoms","score":0.8339999914169312},{"id":"https://openalex.org/keywords/analytical-inversion","display_name":"analytical inversion","score":0.5360000133514404},{"id":"https://openalex.org/keywords/depth-sensitivity","display_name":"depth sensitivity","score":0.4860000014305115}],"concepts":[{"id":"https://openalex.org/C145417883","wikidata":"https://www.wikidata.org/wiki/Q5275421","display_name":"Diffuse optical imaging","level":3,"score":0.6909459829330444},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.5766025185585022},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.566481351852417},{"id":"https://openalex.org/C154954056","wikidata":"https://www.wikidata.org/wiki/Q1604164","display_name":"Transverse plane","level":2,"score":0.5317819118499756},{"id":"https://openalex.org/C2778617687","wikidata":"https://www.wikidata.org/wiki/Q2448456","display_name":"Fluorophore","level":3,"score":0.4929904639720917},{"id":"https://openalex.org/C118530786","wikidata":"https://www.wikidata.org/wiki/Q1134732","display_name":"Instrumentation (computer programming)","level":2,"score":0.48843351006507874},{"id":"https://openalex.org/C2777413408","wikidata":"https://www.wikidata.org/wiki/Q1968843","display_name":"Optical tomography","level":3,"score":0.4753831624984741},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4555893540382385},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.42678534984588623},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3806627094745636},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.37742704153060913},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3603173494338989},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.3596827983856201},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.293906569480896},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C66938386","wikidata":"https://www.wikidata.org/wiki/Q633538","display_name":"Structural engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005453","descriptor_name":"Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025321","descriptor_name":"Surgery, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1117/1.jbo.27.11.116002","doi":"https://doi.org/10.1117/1.jbo.27.11.116002","is_oa":true,"landing_page_url":"https://doi.org/10.1117/1.jbo.27.11.116002","pdf_url":"https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-27/issue-11/116002/Algorithms-and-instrumentation-for-rapid-spatial-frequency-domain-fluorescence-diffuse/10.1117/1.JBO.27.11.116002.pdf","source":{"id":"https://openalex.org/S117354312","display_name":"Journal of Biomedical Optics","issn_l":"1083-3668","issn":["1083-3668","1560-2281"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Optics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9641268","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9641268","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biomed Opt","raw_type":"Text"},{"id":"pmid:36348511","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36348511","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomedical optics","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1117/1.jbo.27.11.116002","doi":"https://doi.org/10.1117/1.jbo.27.11.116002","is_oa":true,"landing_page_url":"https://doi.org/10.1117/1.jbo.27.11.116002","pdf_url":"https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-27/issue-11/116002/Algorithms-and-instrumentation-for-rapid-spatial-frequency-domain-fluorescence-diffuse/10.1117/1.JBO.27.11.116002.pdf","source":{"id":"https://openalex.org/S117354312","display_name":"Journal of Biomedical Optics","issn_l":"1083-3668","issn":["1083-3668","1560-2281"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Optics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1199494025","display_name":"Diffuse Optics for Acute Stroke Management","funder_award_id":"R01NS060653","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3771344960","display_name":"A Resource for Magnetic Resonance and Optical Imaging","funder_award_id":"P41EB015893","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G9000130740","display_name":null,"funder_award_id":"EB015893","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320309370","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10"},{"id":"https://openalex.org/F4320310180","display_name":"Institute for Translational Medicine and Therapeutics","ror":"https://ror.org/00b30xv10"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4308592425.pdf","grobid_xml":"https://content.openalex.org/works/W4308592425.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W608653923","https://openalex.org/W1768281865","https://openalex.org/W1969678816","https://openalex.org/W1979309097","https://openalex.org/W1980422655","https://openalex.org/W1990538901","https://openalex.org/W2023014506","https://openalex.org/W2039728465","https://openalex.org/W2042582517","https://openalex.org/W2063709657","https://openalex.org/W2106147817","https://openalex.org/W2110012738","https://openalex.org/W2123873515","https://openalex.org/W2127476889","https://openalex.org/W2136708034","https://openalex.org/W2163828524","https://openalex.org/W2312123650","https://openalex.org/W2527718370","https://openalex.org/W2530071270","https://openalex.org/W2588162919","https://openalex.org/W2613597769","https://openalex.org/W2724217665","https://openalex.org/W2758371826","https://openalex.org/W2764265920","https://openalex.org/W2886775628","https://openalex.org/W2903910008","https://openalex.org/W2956043600","https://openalex.org/W3037464161","https://openalex.org/W3038056254","https://openalex.org/W3108068113","https://openalex.org/W3136730344","https://openalex.org/W3153624600","https://openalex.org/W3162626667","https://openalex.org/W4213220310"],"related_works":["https://openalex.org/W2082165590","https://openalex.org/W2795095480","https://openalex.org/W2016541074","https://openalex.org/W2340600261","https://openalex.org/W100934958","https://openalex.org/W3135042779","https://openalex.org/W2605810547","https://openalex.org/W2399954257","https://openalex.org/W3037464161","https://openalex.org/W1996085026"],"abstract_inverted_index":{"Significance:":[0],"Rapid":[1],"estimation":[2,35,76],"of":[3,8,36,42,77,89,109,202],"the":[4,13,37,48,57,87,110,117,158,176],"depth":[5,38,80,113],"and":[6,30,39,55,73,81,134,157],"margins":[7,41,103,161],"fluorescence":[9,43,63,91],"targets":[10,127,136],"buried":[11],"below":[12],"tissue":[14],"surface":[15],"could":[16,180],"improve":[17],"upon":[18],"current":[19,203],"image-guided":[20],"surgery":[21,185],"techniques":[22],"for":[23,71],"tumor":[24],"resection.":[25],"Aim:":[26],"We":[27,120],"describe":[28],"algorithms":[29],"instrumentation":[31],"that":[32,175],"permit":[33,200],"rapid":[34,72,177],"transverse":[40,160],"target(s)":[44],"in":[45,129,183,193],"turbid":[46],"media;":[47],"work":[49],"aims":[50],"to":[51,95,97],"introduce,":[52],"experimentally":[53],"demonstrate,":[54],"characterize":[56,121],"methodology.":[58],"Approach:":[59],"Spatial":[60],"frequency":[61],"domain":[62],"diffuse":[64,90],"optical":[65],"tomography":[66],"(SFD-FDOT)":[67],"technique":[68],"is":[69],"adapted":[70],"computationally":[74],"inexpensive":[75],"fluorophore":[78],"target":[79,99],"lateral":[82,102,139],"margins.":[83,170],"The":[84,101,172,198],"algorithm":[85],"utilizes":[86],"variation":[88],"intensity":[92],"with":[93,137],"respect":[94],"spatial-modulation-frequency":[96],"compute":[98],"depth.":[100],"are":[104],"determined":[105],"via":[106],"analytical":[107],"inversion":[108],"data":[111,152],"using":[112,124],"information":[114],"obtained":[115],"from":[116,168],"first":[118,191],"step.":[119],"method":[122],"performance":[123],"fluorescent":[125],"contrast":[126],"embedded":[128],"tissue-simulating":[130],"phantoms.":[131],"Results:":[132],"Single":[133],"multiple":[135],"significant":[138],"size":[140],"were":[141,162],"imaged":[142],"at":[143],"varying":[144],"depths":[145],"as":[146,148,189],"deep":[147],"1":[149],"cm.":[150],"Phantom":[151],"analysis":[153],"showed":[154],"good":[155],"depth-sensitivity,":[156],"reconstructed":[159],"mostly":[163],"within":[164],"\u223c30":[165],"%":[166],"error":[167],"true":[169],"Conclusions:":[171],"study":[173],"suggests":[174],"SFD-FDOT":[178,196],"approach":[179],"be":[181],"useful":[182],"resection":[184],"and,":[186],"more":[187,194],"broadly,":[188],"a":[190],"step":[192],"rigorous":[195],"reconstructions.":[197],"experiments":[199],"evaluation":[201],"limitations.":[204]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-11-12T00:00:00"}