{"id":"https://openalex.org/W4308490641","doi":"https://doi.org/10.1016/j.fpurol.2022.07.084","title":"La m\u00e9thylation d\u2019ADN chez des patients suivis pour tumeur de vessie : \u00e0 propos d\u2019une \u00e9tude prospective","display_name":"La m\u00e9thylation d\u2019ADN chez des patients suivis pour tumeur de vessie : \u00e0 propos d\u2019une \u00e9tude prospective","publication_year":2022,"publication_date":"2022-10-29","ids":{"openalex":"https://openalex.org/W4308490641","doi":"https://doi.org/10.1016/j.fpurol.2022.07.084"},"language":"fr","primary_location":{"id":"doi:10.1016/j.fpurol.2022.07.084","doi":"https://doi.org/10.1016/j.fpurol.2022.07.084","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.fpurol.2022.07.084","pdf_url":null,"source":{"id":"https://openalex.org/S2898272304","display_name":"Progr\u00e8s en Urologie - FMC","issn_l":"1761-676X","issn":["1761-676X","2405-514X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progr\u00e8s en Urologie - FMC","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039859167","display_name":"M. Tetou","orcid":"https://orcid.org/0000-0002-1719-5532","observed_orcids":["https://orcid.org/0000-0002-1719-5532"]},"institutions":[{"id":"https://openalex.org/I126477371","display_name":"Mohammed V University","ror":"https://ror.org/00r8w8f84","country_code":"MA","type":"education","lineage":["https://openalex.org/I126477371"]}],"countries":["MA"],"is_corresponding":true,"raw_author_name":"M. Tetou","raw_affiliation_strings":["Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc","institution_ids":["https://openalex.org/I126477371"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006900579","display_name":"I. Hassan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126477371","display_name":"Mohammed V University","ror":"https://ror.org/00r8w8f84","country_code":"MA","type":"education","lineage":["https://openalex.org/I126477371"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"I. Hassan","raw_affiliation_strings":["Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc","institution_ids":["https://openalex.org/I126477371"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014207714","display_name":"Mohammed Mrabti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126477371","display_name":"Mohammed V University","ror":"https://ror.org/00r8w8f84","country_code":"MA","type":"education","lineage":["https://openalex.org/I126477371"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"M. Mrabti","raw_affiliation_strings":["Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V, Rabat, Maroc","institution_ids":["https://openalex.org/I126477371"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012970323","display_name":"Y. Boukhlifi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y. Boukhlifi","raw_affiliation_strings":["Service urologie. H\u00f4pital militaire d\u2019instruction Mohammed V, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service urologie. H\u00f4pital militaire d\u2019instruction Mohammed V, Rabat, Maroc","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043964320","display_name":"O. Jendouzi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126477371","display_name":"Mohammed V University","ror":"https://ror.org/00r8w8f84","country_code":"MA","type":"education","lineage":["https://openalex.org/I126477371"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"O. Jendouzi","raw_affiliation_strings":["Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V, Rabat, Maroc","institution_ids":["https://openalex.org/I126477371"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047426144","display_name":"Meryem El Azzouzi","orcid":"https://orcid.org/0000-0002-1008-7109","observed_orcids":["https://orcid.org/0000-0002-1008-7109"]},"institutions":[{"id":"https://openalex.org/I4210094396","display_name":"National Centre for Nuclear Energy, Science and Technology","ror":"https://ror.org/00qyat195","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210094396"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"M. El Azzouzi","raw_affiliation_strings":["Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Rabat, Maroc","institution_ids":["https://openalex.org/I4210094396"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052633759","display_name":"Hajar El Ahanidi","orcid":"https://orcid.org/0000-0001-7322-4804","observed_orcids":["https://orcid.org/0000-0001-7322-4804"]},"institutions":[{"id":"https://openalex.org/I126477371","display_name":"Mohammed V University","ror":"https://ror.org/00r8w8f84","country_code":"MA","type":"education","lineage":["https://openalex.org/I126477371"]},{"id":"https://openalex.org/I4210094396","display_name":"National Centre for Nuclear Energy, Science and Technology","ror":"https://ror.org/00qyat195","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210094396"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"H. El Ahanidi","raw_affiliation_strings":["Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat. Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat. Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc","institution_ids":["https://openalex.org/I126477371","https://openalex.org/I4210094396"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012361954","display_name":"C. Hafidi alaoui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126477371","display_name":"Mohammed V University","ror":"https://ror.org/00r8w8f84","country_code":"MA","type":"education","lineage":["https://openalex.org/I126477371"]},{"id":"https://openalex.org/I4210094396","display_name":"National Centre for Nuclear Energy, Science and Technology","ror":"https://ror.org/00qyat195","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210094396"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"C. Hafidi Alaoui","raw_affiliation_strings":["Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Facult\u00e9s des sciences, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Facult\u00e9s des sciences, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc","institution_ids":["https://openalex.org/I126477371","https://openalex.org/I4210094396"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085181191","display_name":"Leila Benbacer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094396","display_name":"National Centre for Nuclear Energy, Science and Technology","ror":"https://ror.org/00qyat195","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210094396"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"L. Benbacer","raw_affiliation_strings":["Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Rabat, Maroc","institution_ids":["https://openalex.org/I4210094396"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073522238","display_name":"Mounia Bensaid","orcid":"https://orcid.org/0000-0001-7322-0627","observed_orcids":["https://orcid.org/0000-0001-7322-0627"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Bensaid","raw_affiliation_strings":["H\u00f4pital militaire Mohammed V, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00f4pital militaire Mohammed V, Rabat, Maroc","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043659188","display_name":"M. Oukabli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126477371","display_name":"Mohammed V University","ror":"https://ror.org/00r8w8f84","country_code":"MA","type":"education","lineage":["https://openalex.org/I126477371"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"M. Oukabli","raw_affiliation_strings":["Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc","institution_ids":["https://openalex.org/I126477371"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028112803","display_name":"A. Al Bouzidi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126477371","display_name":"Mohammed V University","ror":"https://ror.org/00r8w8f84","country_code":"MA","type":"education","lineage":["https://openalex.org/I126477371"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"A. Al Bouzidi","raw_affiliation_strings":["Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat. Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat. Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc","institution_ids":["https://openalex.org/I126477371"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064175572","display_name":"M. El Mzibri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094396","display_name":"National Centre for Nuclear Energy, Science and Technology","ror":"https://ror.org/00qyat195","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210094396"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"M. El Mzibri","raw_affiliation_strings":["Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Rabat, Maroc","institution_ids":["https://openalex.org/I4210094396"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045454500","display_name":"M. Attaleb","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094396","display_name":"National Centre for Nuclear Energy, Science and Technology","ror":"https://ror.org/00qyat195","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210094396"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"M. Attaleb","raw_affiliation_strings":["Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit\u00e9 de Biologie et de Recherche M\u00e9dicale, CNESTEN, Rabat, Maroc","institution_ids":["https://openalex.org/I4210094396"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102160162","display_name":"Ahmed Ameur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126477371","display_name":"Mohammed V University","ror":"https://ror.org/00r8w8f84","country_code":"MA","type":"education","lineage":["https://openalex.org/I126477371"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"A. Ameur","raw_affiliation_strings":["Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc","institution_ids":["https://openalex.org/I126477371"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022237755","display_name":"Mohammed Alami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126477371","display_name":"Mohammed V University","ror":"https://ror.org/00r8w8f84","country_code":"MA","type":"education","lineage":["https://openalex.org/I126477371"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"M. Alami","raw_affiliation_strings":["Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service urologie, H\u00f4pital militaire d\u2019instruction Mohammed V, Facult\u00e9 de m\u00e9decine et de pharmacie de Rabat, Universit\u00e9 Mohammed V de Rabat, Rabat, Maroc","institution_ids":["https://openalex.org/I126477371"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5039859167"],"corresponding_institution_ids":["https://openalex.org/I126477371"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"3","first_page":"S77","last_page":"S78"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.013799999840557575,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.968999981880188},{"id":"https://openalex.org/keywords/promoter-hypermethylation","display_name":"promoter hypermethylation","score":0.9729999899864197},{"id":"https://openalex.org/keywords/bladder-cancer","display_name":"bladder cancer","score":0.9869999885559082},{"id":"https://openalex.org/keywords/htert","display_name":"hTERT","score":0.9160000085830688},{"id":"https://openalex.org/keywords/twist1","display_name":"TWIST1","score":1.0},{"id":"https://openalex.org/keywords/vim","display_name":"VIM","score":0.9940000176429749},{"id":"https://openalex.org/keywords/nidogen-2","display_name":"NID2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.7179999947547913},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.6759999990463257},{"id":"https://openalex.org/keywords/non-muscle-invasive-bladder-cancer","display_name":"non-muscle-invasive bladder cancer","score":0.9160000085830688},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.5559999942779541},{"id":"https://openalex.org/keywords/transurethral-resection-of-bladder-tumor","display_name":"transurethral resection of bladder tumor","score":0.6830000281333923},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.5580000281333923},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.48500001430511475},{"id":"https://openalex.org/keywords/gene-downregulation","display_name":"gene downregulation","score":0.45899999141693115},{"id":"https://openalex.org/keywords/epigenetics","display_name":"epigenetics","score":0.4350000023841858}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.535365104675293},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4524402320384979}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.fpurol.2022.07.084","doi":"https://doi.org/10.1016/j.fpurol.2022.07.084","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.fpurol.2022.07.084","pdf_url":null,"source":{"id":"https://openalex.org/S2898272304","display_name":"Progr\u00e8s en Urologie - FMC","issn_l":"1761-676X","issn":["1761-676X","2405-514X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progr\u00e8s en Urologie - FMC","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4388424387","https://openalex.org/W2197424039","https://openalex.org/W4388445393","https://openalex.org/W7143410513","https://openalex.org/W4200236417","https://openalex.org/W2803709493","https://openalex.org/W6997194492","https://openalex.org/W289260038","https://openalex.org/W2590355921","https://openalex.org/W4392442727"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2022-11-12T00:00:00"}