{"id":"https://openalex.org/W4308153140","doi":"https://doi.org/10.1016/j.envexpbot.2022.105122","title":"Uranium triggers ferroptosis-like cell death in Vicia faba roots by increasing iron accumulation and inhibiting glutathione peroxidase activity","display_name":"Uranium triggers ferroptosis-like cell death in Vicia faba roots by increasing iron accumulation and inhibiting glutathione peroxidase activity","publication_year":2022,"publication_date":"2022-10-31","ids":{"openalex":"https://openalex.org/W4308153140","doi":"https://doi.org/10.1016/j.envexpbot.2022.105122"},"language":"en","primary_location":{"id":"doi:10.1016/j.envexpbot.2022.105122","doi":"https://doi.org/10.1016/j.envexpbot.2022.105122","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.envexpbot.2022.105122","pdf_url":null,"source":{"id":"https://openalex.org/S202986090","display_name":"Environmental and Experimental Botany","issn_l":"0098-8472","issn":["0098-8472","1873-7307"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental and Experimental Botany","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100330006","display_name":"Xi Chen","orcid":"https://orcid.org/0000-0002-9877-2396","observed_orcids":["https://orcid.org/0000-0002-9877-2396"]},"institutions":[{"id":"https://openalex.org/I63354593","display_name":"Sichuan Normal University","ror":"https://ror.org/043dxc061","country_code":"CN","type":"education","lineage":["https://openalex.org/I63354593"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xi Chen","raw_affiliation_strings":["Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China","institution_ids":["https://openalex.org/I63354593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035714699","display_name":"Guo Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63354593","display_name":"Sichuan Normal University","ror":"https://ror.org/043dxc061","country_code":"CN","type":"education","lineage":["https://openalex.org/I63354593"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guo Wu","raw_affiliation_strings":["Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China","Plant Functional Genomics and Bioinformatics Research Center, Sichuan Normal University, Chengdu 610101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China","institution_ids":["https://openalex.org/I63354593"]},{"raw_affiliation_string":"Plant Functional Genomics and Bioinformatics Research Center, Sichuan Normal University, Chengdu 610101, China","institution_ids":["https://openalex.org/I63354593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059874594","display_name":"Yuxi Dang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63354593","display_name":"Sichuan Normal University","ror":"https://ror.org/043dxc061","country_code":"CN","type":"education","lineage":["https://openalex.org/I63354593"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu-Xi Dang","raw_affiliation_strings":["Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China","institution_ids":["https://openalex.org/I63354593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101789591","display_name":"Qingling Li","orcid":"https://orcid.org/0000-0002-8978-7588","observed_orcids":["https://orcid.org/0000-0002-8978-7588"]},"institutions":[{"id":"https://openalex.org/I63354593","display_name":"Sichuan Normal University","ror":"https://ror.org/043dxc061","country_code":"CN","type":"education","lineage":["https://openalex.org/I63354593"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qing-ling Li","raw_affiliation_strings":["Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China","institution_ids":["https://openalex.org/I63354593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053336399","display_name":"Meng-ting Xie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63354593","display_name":"Sichuan Normal University","ror":"https://ror.org/043dxc061","country_code":"CN","type":"education","lineage":["https://openalex.org/I63354593"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Meng-Ting Xie","raw_affiliation_strings":["Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China","institution_ids":["https://openalex.org/I63354593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100318082","display_name":"Wei Li","orcid":"https://orcid.org/0000-0001-9931-5990","observed_orcids":["https://orcid.org/0000-0001-9931-5990"]},"institutions":[{"id":"https://openalex.org/I63354593","display_name":"Sichuan Normal University","ror":"https://ror.org/043dxc061","country_code":"CN","type":"education","lineage":["https://openalex.org/I63354593"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Li","raw_affiliation_strings":["Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China","institution_ids":["https://openalex.org/I63354593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100430372","display_name":"Hong Zhang","orcid":"https://orcid.org/0000-0003-4943-1859","observed_orcids":["https://orcid.org/0000-0003-4943-1859"]},"institutions":[{"id":"https://openalex.org/I63354593","display_name":"Sichuan Normal University","ror":"https://ror.org/043dxc061","country_code":"CN","type":"education","lineage":["https://openalex.org/I63354593"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Zhang","raw_affiliation_strings":["Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Life Science College, Sichuan Normal University, Chengdu, Sichuan 610101, China","institution_ids":["https://openalex.org/I63354593"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046954247","display_name":"Jin-long Lai","orcid":"https://orcid.org/0000-0002-5542-3559","observed_orcids":["https://orcid.org/0000-0002-5542-3559"]},"institutions":[{"id":"https://openalex.org/I1297991670","display_name":"Southwest University of Science and Technology","ror":"https://ror.org/04d996474","country_code":"CN","type":"education","lineage":["https://openalex.org/I1297991670"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jin-Long Lai","raw_affiliation_strings":["Engineering Research Center of Biomass Materials, Ministry of Education, Southwest University of Science and Technology, Mianyang 621010, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Engineering Research Center of Biomass Materials, Ministry of Education, Southwest University of Science and Technology, Mianyang 621010, China","institution_ids":["https://openalex.org/I1297991670"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5035714699","https://openalex.org/A5046954247"],"corresponding_institution_ids":["https://openalex.org/I1297991670","https://openalex.org/I63354593"],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":1.2991,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.80854299,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"205","issue":null,"first_page":"105122","last_page":"105122"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.5698000192642212,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.5698000192642212,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10014","display_name":"Plant Stress Responses and Tolerance","score":0.25609999895095825,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.03959999978542328,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/uranium-toxicity","display_name":"uranium toxicity","score":0.9620000123977661},{"id":"https://openalex.org/keywords/vicia-faba","display_name":"Vicia faba","score":0.8539999723434448},{"id":"https://openalex.org/keywords/iron-accumulation","display_name":"iron accumulation","score":0.7760000228881836},{"id":"https://openalex.org/keywords/glutathione-peroxidase","display_name":"glutathione peroxidase","score":0.9049999713897705},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9860000014305115},{"id":"https://openalex.org/keywords/mitochondrial-morphology","display_name":"mitochondrial morphology","score":0.7770000100135803},{"id":"https://openalex.org/keywords/peroxidase-activity","display_name":"peroxidase activity","score":0.7179999947547913},{"id":"https://openalex.org/keywords/ferrostatin-1","display_name":"ferrostatin-1","score":0.8309999704360962},{"id":"https://openalex.org/keywords/vitamin-e","display_name":"vitamin E","score":0.8949999809265137},{"id":"https://openalex.org/keywords/iron-chelators","display_name":"iron chelators","score":0.7699999809265137},{"id":"https://openalex.org/keywords/heavy-metal-toxicity-in-plants","display_name":"heavy metal phytotoxicity","score":0.800000011920929},{"id":"https://openalex.org/keywords/root-cell-death","display_name":"root cell death","score":0.609000027179718}],"concepts":[{"id":"https://openalex.org/C2992233211","wikidata":"https://www.wikidata.org/wiki/Q131342","display_name":"Vicia faba","level":2,"score":0.7869555950164795},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.7832697033882141},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.6967113018035889},{"id":"https://openalex.org/C158086472","wikidata":"https://www.wikidata.org/wiki/Q21103287","display_name":"GPX4","level":5,"score":0.5882799029350281},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5650634169578552},{"id":"https://openalex.org/C2781264002","wikidata":"https://www.wikidata.org/wiki/Q3724651","display_name":"Phospholipid-hydroperoxide glutathione peroxidase","level":5,"score":0.5096232891082764},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46096086502075195},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.4295623302459717},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41145169734954834},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.40784740447998047},{"id":"https://openalex.org/C2778760513","wikidata":"https://www.wikidata.org/wiki/Q24773045","display_name":"Glutathione peroxidase","level":4,"score":0.38162392377853394},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.3549927771091461},{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.2957739233970642},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.27352625131607056},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.27242833375930786},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.13149195909500122}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.envexpbot.2022.105122","doi":"https://doi.org/10.1016/j.envexpbot.2022.105122","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.envexpbot.2022.105122","pdf_url":null,"source":{"id":"https://openalex.org/S202986090","display_name":"Environmental and Experimental Botany","issn_l":"0098-8472","issn":["0098-8472","1873-7307"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental and Experimental Botany","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.6735000014305115,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1669174029","https://openalex.org/W1997183854","https://openalex.org/W2000686250","https://openalex.org/W2010656744","https://openalex.org/W2038784725","https://openalex.org/W2045204781","https://openalex.org/W2050221235","https://openalex.org/W2080843596","https://openalex.org/W2102652793","https://openalex.org/W2109897883","https://openalex.org/W2153273464","https://openalex.org/W2267117640","https://openalex.org/W2297832822","https://openalex.org/W2377922336","https://openalex.org/W2547303460","https://openalex.org/W2563348538","https://openalex.org/W2577539162","https://openalex.org/W2597874027","https://openalex.org/W2768482093","https://openalex.org/W2895252545","https://openalex.org/W2905483103","https://openalex.org/W2910911994","https://openalex.org/W2949760153","https://openalex.org/W2979807290","https://openalex.org/W2998620691","https://openalex.org/W3024548219","https://openalex.org/W3026541740","https://openalex.org/W3030112010","https://openalex.org/W3037266065","https://openalex.org/W3048364851","https://openalex.org/W3086893610","https://openalex.org/W3093089689","https://openalex.org/W3102801063","https://openalex.org/W3114970301","https://openalex.org/W3120023325","https://openalex.org/W3121008803","https://openalex.org/W3126569431","https://openalex.org/W3127184027","https://openalex.org/W3176576804","https://openalex.org/W3204673926","https://openalex.org/W3214534995","https://openalex.org/W3215478040","https://openalex.org/W4220724485","https://openalex.org/W4220730548","https://openalex.org/W4293085775"],"related_works":["https://openalex.org/W4321748265","https://openalex.org/W2979807290","https://openalex.org/W3026541740","https://openalex.org/W4412106067","https://openalex.org/W3086893610","https://openalex.org/W2923076701","https://openalex.org/W4318982874","https://openalex.org/W2164197565","https://openalex.org/W7128001086","https://openalex.org/W2895252545"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2022-11-08T00:00:00"}