{"id":"https://openalex.org/W4307147131","doi":"https://doi.org/10.1016/j.ijrobp.2022.07.626","title":"Stereotactic Body Radiation Therapy vs. Conventional External Beam Radiation Therapy for Painful Bone Metastases: A Systematic Review and Meta-Analysis of Randomized Trials","display_name":"Stereotactic Body Radiation Therapy vs. Conventional External Beam Radiation Therapy for Painful Bone Metastases: A Systematic Review and Meta-Analysis of Randomized Trials","publication_year":2022,"publication_date":"2022-10-22","ids":{"openalex":"https://openalex.org/W4307147131","doi":"https://doi.org/10.1016/j.ijrobp.2022.07.626"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijrobp.2022.07.626","doi":"https://doi.org/10.1016/j.ijrobp.2022.07.626","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijrobp.2022.07.626","pdf_url":null,"source":{"id":"https://openalex.org/S110533041","display_name":"International Journal of Radiation Oncology*Biology*Physics","issn_l":"0360-3016","issn":["0360-3016","1879-355X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Radiation Oncology*Biology*Physics","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5115601647","display_name":"C.C. Lee","orcid":"https://orcid.org/0009-0004-2323-0973","observed_orcids":["https://orcid.org/0009-0004-2323-0973"]},"institutions":[{"id":"https://openalex.org/I4210103786","display_name":"National University Cancer Institute, Singapore","ror":"https://ror.org/025yypj46","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210103786","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"C.C. Lee","raw_affiliation_strings":["Department of Radiation Oncology, National University Cancer Institute Singapore, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, National University Cancer Institute Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I4210103786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112331092","display_name":"Y.Y. Soon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103786","display_name":"National University Cancer Institute, Singapore","ror":"https://ror.org/025yypj46","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210103786","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Y.Y. Soon","raw_affiliation_strings":["Department of Radiation Oncology, National University Cancer Institute Singapore, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, National University Cancer Institute Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I4210103786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066056034","display_name":"Timothy Cheo","orcid":"https://orcid.org/0000-0002-8783-6454","observed_orcids":["https://orcid.org/0000-0002-8783-6454"]},"institutions":[{"id":"https://openalex.org/I4210103786","display_name":"National University Cancer Institute, Singapore","ror":"https://ror.org/025yypj46","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210103786","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"T. Cheo","raw_affiliation_strings":["Department of Radiation Oncology, National University Cancer Institute Singapore, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, National University Cancer Institute Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I4210103786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087090962","display_name":"Balamurugan A. Vellayappan","orcid":"https://orcid.org/0000-0002-1077-1840","observed_orcids":["https://orcid.org/0000-0002-1077-1840"]},"institutions":[{"id":"https://openalex.org/I4210103786","display_name":"National University Cancer Institute, Singapore","ror":"https://ror.org/025yypj46","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210103786","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"B. Vellayappan","raw_affiliation_strings":["Department of Radiation Oncology, National University Cancer Institute Singapore, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, National University Cancer Institute Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I4210103786"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032649814","display_name":"J. Tey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103786","display_name":"National University Cancer Institute, Singapore","ror":"https://ror.org/025yypj46","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210103786","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"J. Tey","raw_affiliation_strings":["Department of Radiation Oncology, National University Cancer Institute Singapore, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, National University Cancer Institute Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I4210103786"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5115601647"],"corresponding_institution_ids":["https://openalex.org/I4210103786"],"apc_list":{"value":3600,"currency":"USD","value_usd":3600},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"114","issue":"3","first_page":"S150","last_page":"S150"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12108","display_name":"Management of metastatic bone disease","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12108","display_name":"Management of metastatic bone disease","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11600","display_name":"Brain Metastases and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stereotactic-body-radiation-therapy","display_name":"stereotactic body radiotherapy","score":0.9890000224113464},{"id":"https://openalex.org/keywords/external-beam-radiotherapy","display_name":"external beam radiotherapy","score":0.9369999766349792},{"id":"https://openalex.org/keywords/bone-metastases","display_name":"bone metastasis","score":0.9350000023841858},{"id":"https://openalex.org/keywords/bone-pain","display_name":"bone pain","score":0.6150000095367432},{"id":"https://openalex.org/keywords/pain-response","display_name":"pain response","score":0.7260000109672546},{"id":"https://openalex.org/keywords/local-progression","display_name":"local progression","score":0.8939999938011169},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.6840000152587891},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.9110000133514404},{"id":"https://openalex.org/keywords/radiation-induced-fracture","display_name":"radiation-induced fracture","score":0.6420000195503235},{"id":"https://openalex.org/keywords/pain-flare","display_name":"pain flare","score":0.7170000076293945},{"id":"https://openalex.org/keywords/radiation-myelopathy","display_name":"radiation myelopathy","score":0.9919999837875366},{"id":"https://openalex.org/keywords/treatment-related-toxicity","display_name":"treatment toxicity","score":0.5070000290870667},{"id":"https://openalex.org/keywords/grade-certainty-of-evidence","display_name":"GRADE certainty of evidence","score":0.8140000104904175},{"id":"https://openalex.org/keywords/risk-of-bias","display_name":"risk of bias","score":0.6650000214576721}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9651835560798645},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.73232102394104},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6704085469245911},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5794071555137634},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.4772048890590668},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4670965075492859},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.42431578040122986},{"id":"https://openalex.org/C2780387249","wikidata":"https://www.wikidata.org/wiki/Q973234","display_name":"Radiosurgery","level":3,"score":0.42229288816452026},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3546740412712097},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.ijrobp.2022.07.626","doi":"https://doi.org/10.1016/j.ijrobp.2022.07.626","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijrobp.2022.07.626","pdf_url":null,"source":{"id":"https://openalex.org/S110533041","display_name":"International Journal of Radiation Oncology*Biology*Physics","issn_l":"0360-3016","issn":["0360-3016","1879-355X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Radiation Oncology*Biology*Physics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4288808853","https://openalex.org/W4295419309","https://openalex.org/W4307149947","https://openalex.org/W7075731370","https://openalex.org/W4391744365","https://openalex.org/W7221472263","https://openalex.org/W4380263572","https://openalex.org/W4306843015","https://openalex.org/W4306958440","https://openalex.org/W4283464337"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2022-10-28T00:00:00"}