{"id":"https://openalex.org/W4306377291","doi":"https://doi.org/10.1017/cjn.2022.304","title":"Safety Evaluation of Primary Carotid Stenting: Transcranial Doppler and MRI","display_name":"Safety Evaluation of Primary Carotid Stenting: Transcranial Doppler and MRI","publication_year":2022,"publication_date":"2022-10-17","ids":{"openalex":"https://openalex.org/W4306377291","doi":"https://doi.org/10.1017/cjn.2022.304","pmid":"https://pubmed.ncbi.nlm.nih.gov/36245094"},"language":"en","primary_location":{"id":"doi:10.1017/cjn.2022.304","doi":"https://doi.org/10.1017/cjn.2022.304","is_oa":true,"landing_page_url":"https://doi.org/10.1017/cjn.2022.304","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/6F66FB43B0BD618F35F9B9AE1C4EB1E3/S0317167122003043a.pdf/div-class-title-safety-evaluation-of-primary-carotid-stenting-transcranial-doppler-and-mri-div.pdf","source":{"id":"https://openalex.org/S3196323","display_name":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","issn_l":"0317-1671","issn":["0317-1671","2057-0155"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/6F66FB43B0BD618F35F9B9AE1C4EB1E3/S0317167122003043a.pdf/div-class-title-safety-evaluation-of-primary-carotid-stenting-transcranial-doppler-and-mri-div.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066818331","display_name":"David M. Pelz","orcid":"https://orcid.org/0000-0002-7669-7313","observed_orcids":["https://orcid.org/0000-0002-7669-7313"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"David M. Pelz","raw_affiliation_strings":["Departments of Medical Imaging and Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada"],"raw_orcid":"https://orcid.org/0000-0002-7669-7313","affiliations":[{"raw_affiliation_string":"Departments of Medical Imaging and Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038892854","display_name":"Stephen P. Lownie","orcid":"https://orcid.org/0000-0003-4959-6725","observed_orcids":["https://orcid.org/0000-0003-4959-6725"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I129902397","display_name":"Dalhousie University","ror":"https://ror.org/01e6qks80","country_code":"CA","type":"education","lineage":["https://openalex.org/I129902397"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Stephen P. Lownie","raw_affiliation_strings":["Departments of Medical Imaging and Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada","Division of Neurosurgery, Dalhousie University, Halifax, NS, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medical Imaging and Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Division of Neurosurgery, Dalhousie University, Halifax, NS, Canada","institution_ids":["https://openalex.org/I129902397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058197946","display_name":"Urooj F. Iftikhar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Urooj F. Iftikhar","raw_affiliation_strings":["Schulich School of Medicine and Dentistry, Western University, London, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Schulich School of Medicine and Dentistry, Western University, London, ON, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112045447","display_name":"Claudio Munoz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I4405252475","display_name":"Robarts Research Institute","ror":"https://ror.org/01psf3m26","country_code":"CA","type":"facility","lineage":["https://openalex.org/I125749732","https://openalex.org/I4405252475"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Claudio Munoz","raw_affiliation_strings":["Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada","institution_ids":["https://openalex.org/I125749732","https://openalex.org/I4405252475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112873923","display_name":"Pablo L\u00f3pez-Ojeda","orcid":"https://orcid.org/0000-0003-3901-658X","observed_orcids":["https://orcid.org/0000-0003-3901-658X"]},"institutions":[{"id":"https://openalex.org/I2802050225","display_name":"Bellvitge University Hospital","ror":"https://ror.org/00epner96","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I157913058","https://openalex.org/I2802050225","https://openalex.org/I4210153292"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Pablo Lopez-Ojeda","raw_affiliation_strings":["Clinica Sagrada Familia, Hospital de Bellvitge, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinica Sagrada Familia, Hospital de Bellvitge, Barcelona, Spain","institution_ids":["https://openalex.org/I2802050225"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037517826","display_name":"Reza Azarpazhooh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Reza Azarpazhooh","raw_affiliation_strings":["Department of Clinical Neurological Sciences, Schulich School of Medicine and Surgery, Western University, London, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neurological Sciences, Schulich School of Medicine and Surgery, Western University, London, ON, Canada","institution_ids":["https://openalex.org/I125749732"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5066818331"],"corresponding_institution_ids":["https://openalex.org/I125749732"],"apc_list":{"value":2205,"currency":"USD","value_usd":2205},"apc_paid":{"value":2205,"currency":"USD","value_usd":2205},"fwci":0.1755,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.51649356,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"50","issue":"5","first_page":"651","last_page":"655"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carotid-stenosis","display_name":"carotid artery stenosis","score":0.8090000152587891},{"id":"https://openalex.org/keywords/cerebral-embolism","display_name":"cerebral embolism","score":0.8159999847412109},{"id":"https://openalex.org/keywords/microemboli","display_name":"microemboli","score":0.9490000009536743},{"id":"https://openalex.org/keywords/balloon-angioplasty","display_name":"balloon angioplasty","score":0.8679999709129333},{"id":"https://openalex.org/keywords/diffusion-weighted-imaging-lesions","display_name":"diffusion-weighted imaging lesions","score":0.8460000157356262},{"id":"https://openalex.org/keywords/stent-deployment","display_name":"stent deployment","score":0.8460000157356262},{"id":"https://openalex.org/keywords/procedural-safety","display_name":"procedural safety","score":0.5479999780654907},{"id":"https://openalex.org/keywords/symptomatic-carotid-stenosis","display_name":"symptomatic carotid stenosis","score":0.8199999928474426}],"concepts":[{"id":"https://openalex.org/C191616109","wikidata":"https://www.wikidata.org/wiki/Q3512319","display_name":"Transcranial Doppler","level":2,"score":0.7948912382125854},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7658872604370117},{"id":"https://openalex.org/C2779169563","wikidata":"https://www.wikidata.org/wiki/Q5045546","display_name":"Carotid stenting","level":4,"score":0.6259808540344238},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.48368579149246216},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.2029488980770111},{"id":"https://openalex.org/C2781068581","wikidata":"https://www.wikidata.org/wiki/Q5045544","display_name":"Carotid endarterectomy","level":3,"score":0.11199650168418884}],"mesh":[{"descriptor_ui":"D002339","descriptor_name":"Carotid Arteries","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D004617","descriptor_name":"Embolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015607","descriptor_name":"Stents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016893","descriptor_name":"Carotid Stenosis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D016893","descriptor_name":"Carotid Stenosis","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017585","descriptor_name":"Ultrasonography, Doppler, Transcranial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020766","descriptor_name":"Intracranial Embolism","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D020766","descriptor_name":"Intracranial Embolism","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D020766","descriptor_name":"Intracranial Embolism","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D038524","descriptor_name":"Diffusion Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1017/cjn.2022.304","doi":"https://doi.org/10.1017/cjn.2022.304","is_oa":true,"landing_page_url":"https://doi.org/10.1017/cjn.2022.304","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/6F66FB43B0BD618F35F9B9AE1C4EB1E3/S0317167122003043a.pdf/div-class-title-safety-evaluation-of-primary-carotid-stenting-transcranial-doppler-and-mri-div.pdf","source":{"id":"https://openalex.org/S3196323","display_name":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","issn_l":"0317-1671","issn":["0317-1671","2057-0155"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","raw_type":"journal-article"},{"id":"pmid:36245094","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36245094","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1017/cjn.2022.304","doi":"https://doi.org/10.1017/cjn.2022.304","is_oa":true,"landing_page_url":"https://doi.org/10.1017/cjn.2022.304","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/6F66FB43B0BD618F35F9B9AE1C4EB1E3/S0317167122003043a.pdf/div-class-title-safety-evaluation-of-primary-carotid-stenting-transcranial-doppler-and-mri-div.pdf","source":{"id":"https://openalex.org/S3196323","display_name":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","issn_l":"0317-1671","issn":["0317-1671","2057-0155"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4306377291.pdf","grobid_xml":"https://content.openalex.org/works/W4306377291.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W1122092268","https://openalex.org/W1506959497","https://openalex.org/W1718787560","https://openalex.org/W1931075451","https://openalex.org/W1998527195","https://openalex.org/W2000225366","https://openalex.org/W2004617752","https://openalex.org/W2017914279","https://openalex.org/W2018853927","https://openalex.org/W2019465816","https://openalex.org/W2036301547","https://openalex.org/W2094376398","https://openalex.org/W2107645482","https://openalex.org/W2110288150","https://openalex.org/W2125162409","https://openalex.org/W2144106890","https://openalex.org/W2154079847","https://openalex.org/W2154380132","https://openalex.org/W2157487972","https://openalex.org/W2168729202","https://openalex.org/W2169527012","https://openalex.org/W2173409329","https://openalex.org/W2332609836","https://openalex.org/W2343298377","https://openalex.org/W2412560354","https://openalex.org/W2594959528","https://openalex.org/W2599460594","https://openalex.org/W2787226317","https://openalex.org/W2809389088","https://openalex.org/W3009953678","https://openalex.org/W4213358578","https://openalex.org/W4248425111"],"related_works":["https://openalex.org/W2322365443","https://openalex.org/W2282916921","https://openalex.org/W2061052038","https://openalex.org/W2050626432","https://openalex.org/W2018853927","https://openalex.org/W2122712760","https://openalex.org/W2461543068","https://openalex.org/W7019012254","https://openalex.org/W2121939476","https://openalex.org/W2343298377"],"abstract_inverted_index":{"ABSTRACT:":[0],"Background":[1],"and":[2,15,59,85,99,117,143,174,181,189,230,244],"Purpose:":[3],"Cerebral":[4],"emboli":[5,51,159,202,222,227],"are":[6,203,223,228],"generated":[7,52,147,156,204,224],"by":[8,53,148,152,205],"every":[9],"step":[10,55],"of":[11,28,42,50,56,101,105,119,139,192,213,254],"standard":[12],"carotid":[13,18,80,87],"angioplasty":[14,30],"stenting.":[16,88],"Primary":[17],"stenting":[19,58,162],"(PCS)":[20],"is":[21,32,45,218,232,242,245],"a":[22,168],"technique":[23],"in":[24,94,127,133,186,235],"which":[25],"the":[26,36,48,61,115,190,214,252],"use":[27],"balloon":[29],"(BA)":[31],"minimized":[33],"to":[34,46,63,248],"decrease":[35],"embolic":[37],"load.":[38],"The":[39,97,136],"primary":[40,57,161],"aim":[41],"this":[43],"study":[44],"establish":[47],"number":[49,98,116,138],"each":[54,104],"determine":[60],"relationship":[62,170],"new":[64,120,175,183,236,255],"diffusion":[65,237],"(DWI)":[66],"lesions":[67,177,185,238],"on":[68,239],"subsequent":[69],"magnetic":[70],"resonance":[71],"imaging":[72],"(MRI).":[73],"Methods:":[74],"Eighty-five":[75],"patients":[76],"with":[77,114],"severe,":[78],"symptomatic":[79],"stenosis":[81,194],"were":[82,109,146],"prospectively":[83],"recruited":[84],"underwent":[86],"Intraoperative":[89],"transcranial":[90],"Doppler":[91],"was":[92,112,125,131,141,167],"performed":[93,126],"77":[95],"patients.":[96,129,135],"size":[100],"microemboli":[102,140,145,173],"for":[103,251],"seven":[106],"procedural":[107],"steps":[108],"recorded.":[110],"Correlation":[111],"made":[113],"location":[118],"DWI":[121,176,184,256],"lesions.":[122,257],"Results:":[123],"PCS":[124,241],"73":[128],"BA":[130,217],"required":[132],"12":[134],"mean":[137],"114,":[142],"most":[144],"stent":[149,206],"deployment,":[150],"followed":[151],"BA.":[153],"Balloon":[154],"techniques":[155],"significantly":[157],"more":[158,201,220],"than":[160,208],"(p":[163,178,195],"=":[164,179,196],"0.017).":[165],"There":[166],"significant":[169],"between":[171,182],"total":[172,226],"0.009),":[180],"multiple":[187],"territories":[188],"severity":[191],"pretreatment":[193],"0.002).":[197],"Conclusions:":[198],"During":[199],"PCS,":[200],"deployment":[207],"during":[209],"any":[210],"other":[211],"stage":[212],"procedure.":[215],"When":[216],"necessary,":[219],"malignant":[221],"but":[225],"unchanged":[229],"there":[231],"no":[233],"difference":[234],"MRI.":[240],"safe":[243],"not":[246],"inferior":[247],"historical":[249],"controls":[250],"generation":[253]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-10-17T00:00:00"}