{"id":"https://openalex.org/W4306354500","doi":"https://doi.org/10.7759/cureus.30358","title":"Adipose Tissue Grafting for the Treatment of Morphea En Coup De Sabre: A Simple Filler or an Emerging Cellular Therapy?","display_name":"Adipose Tissue Grafting for the Treatment of Morphea En Coup De Sabre: A Simple Filler or an Emerging Cellular Therapy?","publication_year":2022,"publication_date":"2022-10-16","ids":{"openalex":"https://openalex.org/W4306354500","doi":"https://doi.org/10.7759/cureus.30358","pmid":"https://pubmed.ncbi.nlm.nih.gov/36407158","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9665929"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.30358","doi":"https://doi.org/10.7759/cureus.30358","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.30358","pdf_url":"https://assets.cureus.com/uploads/case_report/pdf/95925/20221115-26862-1v6pe1y.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://assets.cureus.com/uploads/case_report/pdf/95925/20221115-26862-1v6pe1y.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104006540","display_name":"Mounia El Omari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119819","display_name":"Universit\u00e9 Mohammed VI des Sciences et de la Sant\u00e9","ror":"https://ror.org/01tezat55","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210119819"]},{"id":"https://openalex.org/I4210145847","display_name":"H\u00f4pital Universitaire International Cheikh Khalifa","ror":"https://ror.org/03g26ah87","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210145847"]}],"countries":["MA"],"is_corresponding":true,"raw_author_name":"Mounia El Omari","raw_affiliation_strings":["Plastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR",". Medicine, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR","institution_ids":["https://openalex.org/I4210119819","https://openalex.org/I4210145847"]},{"raw_affiliation_string":". Medicine, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR","institution_ids":["https://openalex.org/I4210119819","https://openalex.org/I4210145847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047735529","display_name":"Malak Debbarh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119819","display_name":"Universit\u00e9 Mohammed VI des Sciences et de la Sant\u00e9","ror":"https://ror.org/01tezat55","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210119819"]},{"id":"https://openalex.org/I4210145847","display_name":"H\u00f4pital Universitaire International Cheikh Khalifa","ror":"https://ror.org/03g26ah87","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210145847"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Malak Debbarh","raw_affiliation_strings":["Plastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR","institution_ids":["https://openalex.org/I4210119819","https://openalex.org/I4210145847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066558290","display_name":"Mohamed Amine Lakhdari","orcid":"https://orcid.org/0000-0002-6963-7099","observed_orcids":["https://orcid.org/0000-0002-6963-7099"]},"institutions":[{"id":"https://openalex.org/I4210119819","display_name":"Universit\u00e9 Mohammed VI des Sciences et de la Sant\u00e9","ror":"https://ror.org/01tezat55","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210119819"]},{"id":"https://openalex.org/I4210145847","display_name":"H\u00f4pital Universitaire International Cheikh Khalifa","ror":"https://ror.org/03g26ah87","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210145847"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Mohamed Amine Lakhdari","raw_affiliation_strings":["Plastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR","institution_ids":["https://openalex.org/I4210119819","https://openalex.org/I4210145847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088335934","display_name":"Zineb Basri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119819","display_name":"Universit\u00e9 Mohammed VI des Sciences et de la Sant\u00e9","ror":"https://ror.org/01tezat55","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210119819"]},{"id":"https://openalex.org/I4210145847","display_name":"H\u00f4pital Universitaire International Cheikh Khalifa","ror":"https://ror.org/03g26ah87","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210145847"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Zineb Basri","raw_affiliation_strings":["Medicine, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR",". Plastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR","institution_ids":["https://openalex.org/I4210119819","https://openalex.org/I4210145847"]},{"raw_affiliation_string":". Plastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR","institution_ids":["https://openalex.org/I4210119819","https://openalex.org/I4210145847"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044547777","display_name":"R Benhamou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119819","display_name":"Universit\u00e9 Mohammed VI des Sciences et de la Sant\u00e9","ror":"https://ror.org/01tezat55","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210119819"]},{"id":"https://openalex.org/I4210145847","display_name":"H\u00f4pital Universitaire International Cheikh Khalifa","ror":"https://ror.org/03g26ah87","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210145847"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Rita Ait Benhamou","raw_affiliation_strings":["Plastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plastic and Reconstructive Surgery, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR","institution_ids":["https://openalex.org/I4210119819","https://openalex.org/I4210145847"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5104006540"],"corresponding_institution_ids":["https://openalex.org/I4210119819","https://openalex.org/I4210145847"],"apc_list":null,"apc_paid":null,"fwci":1.377,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.78586143,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"14","issue":"10","first_page":"e30358","last_page":"e30358"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":0.9423999786376953,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":0.9423999786376953,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11322","display_name":"Facial Rejuvenation and Surgery Techniques","score":0.024900000542402267,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":0.011699999682605267,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/localized-scleroderma","display_name":"morphea","score":0.906000018119812},{"id":"https://openalex.org/keywords/fat-grafting","display_name":"fat grafting","score":0.9879999756813049},{"id":"https://openalex.org/keywords/facial-scars","display_name":"facial scars","score":0.47699999809265137},{"id":"https://openalex.org/keywords/alopecia","display_name":"hair loss","score":0.7099999785423279},{"id":"https://openalex.org/keywords/cosmetic-outcome","display_name":"cosmetic outcome","score":0.5260000228881836},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.6259999871253967},{"id":"https://openalex.org/keywords/collagen-overproduction","display_name":"collagen overproduction","score":0.734000027179718},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.7049999833106995}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9324905276298523},{"id":"https://openalex.org/C2775938904","wikidata":"https://www.wikidata.org/wiki/Q3324389","display_name":"Morphea","level":3,"score":0.7665334939956665},{"id":"https://openalex.org/C2779967694","wikidata":"https://www.wikidata.org/wiki/Q1383511","display_name":"Scleroderma (fungus)","level":3,"score":0.6078029870986938},{"id":"https://openalex.org/C2910390209","wikidata":"https://www.wikidata.org/wiki/Q3324389","display_name":"Localized Scleroderma","level":3,"score":0.5492010116577148},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.5268753170967102},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.5157275795936584},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.489289253950119},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.45592430233955383},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4459383189678192},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.4323440194129944},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3977992832660675},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3418582081794739},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15247821807861328},{"id":"https://openalex.org/C180032290","wikidata":"https://www.wikidata.org/wiki/Q1664296","display_name":"Inoculation","level":2,"score":0.0},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.0},{"id":"https://openalex.org/C2776552008","wikidata":"https://www.wikidata.org/wiki/Q1641400","display_name":"Lichen sclerosus","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.7759/cureus.30358","doi":"https://doi.org/10.7759/cureus.30358","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.30358","pdf_url":"https://assets.cureus.com/uploads/case_report/pdf/95925/20221115-26862-1v6pe1y.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},{"id":"pmid:36407158","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36407158","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:9665929","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9665929/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.7759/cureus.30358","doi":"https://doi.org/10.7759/cureus.30358","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.30358","pdf_url":"https://assets.cureus.com/uploads/case_report/pdf/95925/20221115-26862-1v6pe1y.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4306354500.pdf","grobid_xml":"https://content.openalex.org/works/W4306354500.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1988527938","https://openalex.org/W2002362842","https://openalex.org/W2013737401","https://openalex.org/W2014139103","https://openalex.org/W2065290803","https://openalex.org/W2070126777","https://openalex.org/W2075184591","https://openalex.org/W2081163651","https://openalex.org/W2088899972","https://openalex.org/W2090631808","https://openalex.org/W2095374912","https://openalex.org/W2173497140","https://openalex.org/W2264349843","https://openalex.org/W2326366005","https://openalex.org/W2605187236","https://openalex.org/W2809833064","https://openalex.org/W2886681889","https://openalex.org/W2896249608","https://openalex.org/W2897205889"],"related_works":["https://openalex.org/W2400495639","https://openalex.org/W3027467678","https://openalex.org/W3181860195","https://openalex.org/W2264349843","https://openalex.org/W2075111407","https://openalex.org/W7133341377","https://openalex.org/W2057856413","https://openalex.org/W3113417778","https://openalex.org/W4380083382","https://openalex.org/W3178658013"],"abstract_inverted_index":{"Linear":[0],"scleroderma":[1,16],"en":[2,125],"coup":[3,126],"de":[4,127],"sabre":[5,128],"is":[6,42,120],"a":[7,94,102,111],"rare":[8],"chronic":[9],"autoimmune":[10],"disease.":[11],"This":[12,38],"form":[13],"of":[14,22,35,98,104,154],"localized":[15],"manifests":[17],"through":[18,110],"an":[19,58],"inflammatory":[20],"phenomenon":[21],"collagen":[23],"overproduction":[24],"and":[25,32,46,68,107,142],"extracellular":[26],"matrix":[27],"destruction,":[28],"affecting":[29],"the":[30,36,64],"skin":[31],"subcutaneous":[33],"tissues":[34],"face.":[37],"active":[39],"pathological":[40],"process":[41],"challenging":[43],"to":[44],"control":[45],"often":[47],"goes":[48],"unnoticed":[49],"at":[50],"its":[51,133,139],"early":[52],"stage.":[53],"The":[54],"sequelae":[55,82],"manifest":[56],"as":[57],"alopecic":[59],"frontal":[60],"scar":[61],"lesion,":[62],"causing":[63],"patient":[65],"significant":[66],"aesthetic":[67,81,96],"psychological":[69],"damage.":[70],"In":[71],"this":[72,155],"study,":[73],"we":[74],"report":[75],"two":[76],"clinical":[77],"cases":[78],"in":[79],"which":[80,146],"were":[83],"treated":[84],"by":[85,101],"autologous":[86],"fat":[87,118],"transplantation.":[88],"We":[89],"found":[90],"encouraging":[91],"results,":[92],"with":[93],"global":[95],"improvement":[97],"86.2%":[99],"measured":[100],"jury":[103],"medical":[105],"specialists":[106],"outcome":[108],"stability":[109],"nine-year":[112],"follow-up":[113],"for":[114,122,132,138,151],"one":[115],"patient.":[116],"Autologous":[117],"transfer":[119],"excellent":[121],"treating":[123],"stabilized":[124],"morphea,":[129],"not":[130],"only":[131],"filling":[134],"abilities":[135],"but":[136],"also":[137],"regeneration":[140],"activating":[141],"inflammation":[143],"regulating":[144],"abilities,":[145],"could":[147],"open":[148],"new":[149],"prospects":[150],"curative":[152],"treatment":[153],"pathology.":[156]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-10-16T00:00:00"}