{"id":"https://openalex.org/W4306181587","doi":"https://doi.org/10.17650/2219-4614-2022-14-3-26-32","title":"Prospective trial of efficiency and safety of fibrin sealant criofit after autologous breast reconstruction in stages I\u2013III breast cancer","display_name":"Prospective trial of efficiency and safety of fibrin sealant criofit after autologous breast reconstruction in stages I\u2013III breast cancer","publication_year":2022,"publication_date":"2022-10-12","ids":{"openalex":"https://openalex.org/W4306181587","doi":"https://doi.org/10.17650/2219-4614-2022-14-3-26-32"},"language":"en","primary_location":{"id":"doi:10.17650/2219-4614-2022-14-3-26-32","doi":"https://doi.org/10.17650/2219-4614-2022-14-3-26-32","is_oa":true,"landing_page_url":"https://doi.org/10.17650/2219-4614-2022-14-3-26-32","pdf_url":"https://sarbon.elpub.ru/jour/article/download/575/570","source":{"id":"https://openalex.org/S4210172299","display_name":"Bone and soft tissue sarcomas tumors of the skin","issn_l":"2219-4614","issn":["2219-4614","2782-3687"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone and soft tissue sarcomas, tumors of the skin","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://sarbon.elpub.ru/jour/article/download/575/570","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031930981","display_name":"Vladimir Yu. Ivashkov","orcid":"https://orcid.org/0000-0003-3872-7478","observed_orcids":["https://orcid.org/0000-0003-3872-7478"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V. Yu. Ivashkov","raw_affiliation_strings":["Medsi Group"],"raw_orcid":"https://orcid.org/0000-0003-3872-7478","affiliations":[{"raw_affiliation_string":"Medsi Group","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113037778","display_name":"K. Zirov","orcid":"https://orcid.org/0000-0001-5486-7708","observed_orcids":["https://orcid.org/0000-0001-5486-7708"]},"institutions":[{"id":"https://openalex.org/I4210092247","display_name":"Leningrad Regional Cancer Center","ror":"https://ror.org/00hkez230","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210092247"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"K. Yu. Zirov","raw_affiliation_strings":["L.D. Roman Leningrad Regional Clinical Oncological Dispensary"],"raw_orcid":"https://orcid.org/0000-0001-5486-7708","affiliations":[{"raw_affiliation_string":"L.D. Roman Leningrad Regional Clinical Oncological Dispensary","institution_ids":["https://openalex.org/I4210092247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008386957","display_name":"\u041a\u043e\u043f\u044b\u0442\u0438\u0447 \u0418\u0433\u043e\u0440\u044c \u0412\u0438\u043a\u0442\u043e\u0440\u043e\u0432\u0438\u0447","orcid":"https://orcid.org/0000-0003-2713-0115","observed_orcids":["https://orcid.org/0000-0003-2713-0115"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I. V. Kopytich","raw_affiliation_strings":["Medsi Group"],"raw_orcid":"https://orcid.org/0000-0003-2713-0115","affiliations":[{"raw_affiliation_string":"Medsi Group","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055821514","display_name":"Roman Pesotsky","orcid":"https://orcid.org/0000-0002-2573-2211","observed_orcids":["https://orcid.org/0000-0002-2573-2211"]},"institutions":[{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"R. S. Pesotsky","raw_affiliation_strings":["N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia"],"raw_orcid":"https://orcid.org/0000-0002-2573-2211","affiliations":[{"raw_affiliation_string":"N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia","institution_ids":["https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060462995","display_name":"S.V. Semenov","orcid":"https://orcid.org/0000-0002-4291-5765","observed_orcids":["https://orcid.org/0000-0002-4291-5765"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. V. Semenov","raw_affiliation_strings":["Medsi Group"],"raw_orcid":"https://orcid.org/0000-0002-4291-5765","affiliations":[{"raw_affiliation_string":"Medsi Group","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067649306","display_name":"Alexander Bessonov","orcid":"https://orcid.org/0000-0002-6649-7641","observed_orcids":["https://orcid.org/0000-0002-6649-7641"]},"institutions":[{"id":"https://openalex.org/I4210092247","display_name":"Leningrad Regional Cancer Center","ror":"https://ror.org/00hkez230","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210092247"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"A. A. Bessonov","raw_affiliation_strings":["L.D. Roman Leningrad Regional Clinical Oncological Dispensary"],"raw_orcid":"https://orcid.org/0000-0002-6649-7641","affiliations":[{"raw_affiliation_string":"L.D. Roman Leningrad Regional Clinical Oncological Dispensary","institution_ids":["https://openalex.org/I4210092247"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"3","first_page":"26","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11258","display_name":"Breast Implant and Reconstruction","score":0.9042999744415283,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11258","display_name":"Breast Implant and Reconstruction","score":0.9042999744415283,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12548","display_name":"Hemostasis and retained surgical items","score":0.06750000268220901,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10599","display_name":"Reconstructive Surgery and Microvascular Techniques","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/autologous-breast-reconstruction","display_name":"autologous breast reconstruction","score":0.9789999723434448},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.7680000066757202},{"id":"https://openalex.org/keywords/seroma-prevention","display_name":"seroma prevention","score":0.8830000162124634},{"id":"https://openalex.org/keywords/drain-removal-timing","display_name":"drain removal timing","score":0.6069999933242798},{"id":"https://openalex.org/keywords/postoperative-drainage-volume","display_name":"postoperative drainage volume","score":0.5680000185966492},{"id":"https://openalex.org/keywords/breast-conserving-surgery","display_name":"breast-conserving surgery","score":0.5600000023841858}],"concepts":[{"id":"https://openalex.org/C2779409168","wikidata":"https://www.wikidata.org/wiki/Q727291","display_name":"Seroma","level":3,"score":0.9447227716445923},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9032392501831055},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.7378334999084473},{"id":"https://openalex.org/C2775883587","wikidata":"https://www.wikidata.org/wiki/Q1427914","display_name":"Sealant","level":2,"score":0.7295515537261963},{"id":"https://openalex.org/C2781001896","wikidata":"https://www.wikidata.org/wiki/Q994507","display_name":"Breast reconstruction","level":4,"score":0.640582263469696},{"id":"https://openalex.org/C54173615","wikidata":"https://www.wikidata.org/wiki/Q27205","display_name":"Fibrin","level":2,"score":0.640229344367981},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6082403063774109},{"id":"https://openalex.org/C2777757722","wikidata":"https://www.wikidata.org/wiki/Q848318","display_name":"Mastectomy","level":4,"score":0.5902755260467529},{"id":"https://openalex.org/C2781037480","wikidata":"https://www.wikidata.org/wiki/Q11002196","display_name":"Mammaplasty","level":2,"score":0.45075884461402893},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4362866282463074},{"id":"https://openalex.org/C81182388","wikidata":"https://www.wikidata.org/wiki/Q353963","display_name":"Complication","level":2,"score":0.4180334508419037},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.296233594417572},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1079513430595398},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.17650/2219-4614-2022-14-3-26-32","doi":"https://doi.org/10.17650/2219-4614-2022-14-3-26-32","is_oa":true,"landing_page_url":"https://doi.org/10.17650/2219-4614-2022-14-3-26-32","pdf_url":"https://sarbon.elpub.ru/jour/article/download/575/570","source":{"id":"https://openalex.org/S4210172299","display_name":"Bone and soft tissue sarcomas tumors of the skin","issn_l":"2219-4614","issn":["2219-4614","2782-3687"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone and soft tissue sarcomas, tumors of the skin","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.17650/2219-4614-2022-14-3-26-32","doi":"https://doi.org/10.17650/2219-4614-2022-14-3-26-32","is_oa":true,"landing_page_url":"https://doi.org/10.17650/2219-4614-2022-14-3-26-32","pdf_url":"https://sarbon.elpub.ru/jour/article/download/575/570","source":{"id":"https://openalex.org/S4210172299","display_name":"Bone and soft tissue sarcomas tumors of the skin","issn_l":"2219-4614","issn":["2219-4614","2782-3687"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone and soft tissue sarcomas, tumors of the skin","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4306181587.pdf","grobid_xml":"https://content.openalex.org/works/W4306181587.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1999957775","https://openalex.org/W2013860415","https://openalex.org/W2026922206","https://openalex.org/W2034858243","https://openalex.org/W2041750930","https://openalex.org/W2064485818","https://openalex.org/W2067420088","https://openalex.org/W2097027477","https://openalex.org/W2130495209","https://openalex.org/W2130746306","https://openalex.org/W2331889019","https://openalex.org/W2346953327","https://openalex.org/W2420401027","https://openalex.org/W2546495771","https://openalex.org/W2790145394","https://openalex.org/W3047733773","https://openalex.org/W3128646645"],"related_works":["https://openalex.org/W7220452842","https://openalex.org/W2054573351","https://openalex.org/W2130495209","https://openalex.org/W3128765091","https://openalex.org/W3036119233","https://openalex.org/W7117677850","https://openalex.org/W2049550642","https://openalex.org/W2086448714","https://openalex.org/W2334273916","https://openalex.org/W2119937105"],"abstract_inverted_index":{"Introduction.":[0],"Breast":[1],"cancer":[2],"is":[3,15,23,31,60],"the":[4,18,24,109,195,210],"most":[5],"common":[6,32],"cancer.":[7],"Success":[8],"in":[9,53,86,101,143,152,172,177,215,242],"early":[10],"diagnostic":[11],"and":[12,57,96,123,225],"system":[13],"treatment":[14],"achieved.":[16],"All":[17],"same":[19],"mastectomy":[20],"with":[21,88,179],"reconstruction":[22,52,85],"best":[25],"option":[26],"for":[27],"some":[28],"patients.":[29],"Seroma":[30,170],"complication":[33],"after":[34,49,82,138,204,218],"reconstructive":[35],"plastic":[36],"surgery.Aim.":[37],"To":[38],"analyze":[39],"efficiency":[40,196],"of":[41,65,72,76,148,150,197,212,221,223],"using":[42],"fibrin":[43,66,198],"sealant":[44,67,199],"criofit":[45,68,153,200],"at":[46,79,201],"donor":[47,80,202],"zone":[48,81,203],"autologous":[50,83,205],"breast":[51,84,206],"decreasing":[54],"seroma":[55,73,226],"incidences.Materials":[56],"methods.":[58],"This":[59],"randomised":[61],"controlled":[62],"clinical":[63,232],"trial":[64],"effect":[69],"on":[70,108],"assessing":[71],"incidences,":[74],"timing":[75],"drain":[77,105],"removal":[78,94],"comparison":[87,178],"control":[89,180],"group.":[90,145],"Surgical":[91],"technic,":[92],"drains":[93],"criteria":[95],"patients":[97],"characteristics":[98],"were":[99],"identical":[100],"both":[102],"groups.Results.":[103],"Average":[104,146],"fluid":[106],"volume":[107,211],"first":[110,216],"day":[111,125],"(150.9":[112],"\u00b1":[113,118,127,132,159,164],"40.7":[114],"ml":[115,129],"vs":[116,130,162,184],"190.6":[117],"60.7":[119],"ml;":[120,134],"p":[121,135,167],"0.001)":[122],"second":[124],"(152.6":[126],"53.3":[128],"184.9":[131],"90.3":[133],"=":[136,168],"0.04)":[137],"surgery":[139,243],"was":[140,155,175,188],"significantly":[141,156],"lower":[142,157,176],"experimental":[144,173],"number":[147,220],"days":[149,161,217,222],"drainage":[151,224],"group":[154,174,181],"(6.3":[158],"1.1":[160],"7.4":[163],"2.1":[165],"days;":[166],"0.01).":[169],"incidences":[171,227],"(10":[182],"%":[183],"23":[185],"%).":[186],"It":[187],"statistically":[189],"significant.Conclusion.":[190],"We":[191],"aimed":[192],"to":[193],"asses":[194],"reconstruction.":[207],"Criofit":[208],"decrese":[209],"serous":[213],"draining":[214],"surgery,":[219],"significantly.":[228],"But":[229],"more":[230],"powerful":[231],"trials":[233],"are":[234,238],"needed.":[235],"Study":[236],"limitations":[237],"small":[239,245],"sample,":[240],"changes":[241],"team,":[244],"observation":[246],"period.":[247]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2022-10-14T00:00:00"}