{"id":"https://openalex.org/W4306181562","doi":"https://doi.org/10.1016/j.addr.2022.114569","title":"RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer","display_name":"RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer","publication_year":2022,"publication_date":"2022-10-14","ids":{"openalex":"https://openalex.org/W4306181562","doi":"https://doi.org/10.1016/j.addr.2022.114569","pmid":"https://pubmed.ncbi.nlm.nih.gov/36252617","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10411638"},"language":"en","primary_location":{"id":"doi:10.1016/j.addr.2022.114569","doi":"https://doi.org/10.1016/j.addr.2022.114569","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.addr.2022.114569","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0169409X22004598/pdf","source":{"id":"https://openalex.org/S114437232","display_name":"Advanced Drug Delivery Reviews","issn_l":"0169-409X","issn":["0169-409X","1872-8294"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Drug Delivery Reviews","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S0169409X22004598/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064427446","display_name":"Meghna Mehta","orcid":"https://orcid.org/0000-0001-7636-4749","observed_orcids":["https://orcid.org/0000-0001-7636-4749"]},"institutions":[{"id":"https://openalex.org/I4390039380","display_name":"OU Health Stephenson Cancer Center","ror":"https://ror.org/02bmcqd02","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039271","https://openalex.org/I4390039380"]},{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Meghna Mehta","raw_affiliation_strings":["Department of Radiation Oncology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA; Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","Department of Radiation Oncology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA; Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","institution_ids":["https://openalex.org/I4390039380","https://openalex.org/I49332381"]},{"raw_affiliation_string":"Department of Radiation Oncology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","institution_ids":["https://openalex.org/I49332381"]},{"raw_affiliation_string":"Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","institution_ids":["https://openalex.org/I4390039380","https://openalex.org/I49332381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072157708","display_name":"Rajeswari Raguraman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4390039380","display_name":"OU Health Stephenson Cancer Center","ror":"https://ror.org/02bmcqd02","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039271","https://openalex.org/I4390039380"]},{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rajeswari Raguraman","raw_affiliation_strings":["Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA; Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA; Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","institution_ids":["https://openalex.org/I4390039380","https://openalex.org/I49332381"]},{"raw_affiliation_string":"Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","institution_ids":["https://openalex.org/I49332381"]},{"raw_affiliation_string":"Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","institution_ids":["https://openalex.org/I4390039380","https://openalex.org/I49332381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068736204","display_name":"Rajagopal Ramesh","orcid":"https://orcid.org/0000-0002-7658-5338","observed_orcids":["https://orcid.org/0000-0002-7658-5338"]},"institutions":[{"id":"https://openalex.org/I4390039380","display_name":"OU Health Stephenson Cancer Center","ror":"https://ror.org/02bmcqd02","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039271","https://openalex.org/I4390039380"]},{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rajagopal Ramesh","raw_affiliation_strings":["Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA; Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA; Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","institution_ids":["https://openalex.org/I4390039380","https://openalex.org/I49332381"]},{"raw_affiliation_string":"Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","institution_ids":["https://openalex.org/I49332381"]},{"raw_affiliation_string":"Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","institution_ids":["https://openalex.org/I4390039380","https://openalex.org/I49332381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085523826","display_name":"Anupama Munshi","orcid":"https://orcid.org/0000-0003-1466-1419","observed_orcids":["https://orcid.org/0000-0003-1466-1419"]},"institutions":[{"id":"https://openalex.org/I4390039380","display_name":"OU Health Stephenson Cancer Center","ror":"https://ror.org/02bmcqd02","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039271","https://openalex.org/I4390039380"]},{"id":"https://openalex.org/I49332381","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I49332381"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Anupama Munshi","raw_affiliation_strings":["Department of Radiation Oncology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA; Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA. Electronic address: amunshi@ouhsc.edu","Department of Radiation Oncology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA; Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA. Electronic address: amunshi@ouhsc.edu","institution_ids":["https://openalex.org/I4390039380","https://openalex.org/I49332381"]},{"raw_affiliation_string":"Department of Radiation Oncology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","institution_ids":["https://openalex.org/I49332381"]},{"raw_affiliation_string":"Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73013, USA","institution_ids":["https://openalex.org/I4390039380","https://openalex.org/I49332381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5085523826"],"corresponding_institution_ids":["https://openalex.org/I4390039380","https://openalex.org/I49332381"],"apc_list":{"value":5150,"currency":"USD","value_usd":5150},"apc_paid":{"value":5150,"currency":"USD","value_usd":5150},"fwci":1.418,"has_fulltext":true,"cited_by_count":67,"citation_normalized_percentile":{"value":0.8352707,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"191","issue":null,"first_page":"114569","last_page":"114569"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rna-binding-proteins","display_name":"RNA-binding proteins","score":0.968999981880188},{"id":"https://openalex.org/keywords/post-transcriptional-regulation","display_name":"post-transcriptional regulation","score":0.8970000147819519},{"id":"https://openalex.org/keywords/dna-damage-response","display_name":"DNA damage response","score":0.9779999852180481},{"id":"https://openalex.org/keywords/radiation-response","display_name":"radiation response","score":0.9570000171661377},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.5759999752044678},{"id":"https://openalex.org/keywords/hur","display_name":"HuR","score":0.9309999942779541},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.7850000262260437},{"id":"https://openalex.org/keywords/cancer-therapy-targets","display_name":"cancer therapy targets","score":0.5289999842643738},{"id":"https://openalex.org/keywords/rbm38","display_name":"RBM38","score":0.6970000267028809},{"id":"https://openalex.org/keywords/auf1","display_name":"AUF1","score":0.8339999914169312},{"id":"https://openalex.org/keywords/lin28","display_name":"Lin28","score":0.8050000071525574},{"id":"https://openalex.org/keywords/rbm24","display_name":"RBM24","score":0.8740000128746033},{"id":"https://openalex.org/keywords/musashi","display_name":"Musashi","score":0.9150000214576721},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.7459999918937683},{"id":"https://openalex.org/keywords/oncoprotein","display_name":"oncoprotein","score":0.9860000014305115}],"concepts":[{"id":"https://openalex.org/C41282012","wikidata":"https://www.wikidata.org/wiki/Q3928341","display_name":"RNA-binding protein","level":4,"score":0.8142803311347961},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7060986161231995},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.5546219348907471},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5509150624275208},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.5346279144287109},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.4960730969905853},{"id":"https://openalex.org/C27153228","wikidata":"https://www.wikidata.org/wiki/Q3787274","display_name":"Transcriptional regulation","level":4,"score":0.46196502447128296},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.45729032158851624},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.45068517327308655},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.42985376715660095},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4066212773323059},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.39092808961868286},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3241921663284302},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2929363250732422},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.2706848382949829}],"mesh":[{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.addr.2022.114569","doi":"https://doi.org/10.1016/j.addr.2022.114569","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.addr.2022.114569","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0169409X22004598/pdf","source":{"id":"https://openalex.org/S114437232","display_name":"Advanced Drug Delivery Reviews","issn_l":"0169-409X","issn":["0169-409X","1872-8294"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Drug Delivery Reviews","raw_type":"journal-article"},{"id":"pmid:36252617","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36252617","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced drug delivery reviews","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10411638","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10411638","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10411638/pdf/nihms-1917487.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Adv Drug Deliv Rev","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.addr.2022.114569","doi":"https://doi.org/10.1016/j.addr.2022.114569","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.addr.2022.114569","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0169409X22004598/pdf","source":{"id":"https://openalex.org/S114437232","display_name":"Advanced Drug Delivery Reviews","issn_l":"0169-409X","issn":["0169-409X","1872-8294"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Drug Delivery Reviews","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1181589793","display_name":null,"funder_award_id":"GM103639","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G285398573","display_name":null,"funder_award_id":"I01 BX003420","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G4473694703","display_name":"Mentoring Translational Cancer Research in Oklahoma","funder_award_id":"P20GM103639","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G501766673","display_name":null,"funder_award_id":"#P30CA225520","funder_id":"https://openalex.org/F4320333795","funder_display_name":"Stephenson Cancer Center"},{"id":"https://openalex.org/G5246722282","display_name":"An improved IL-24 gene-based therapeutic for cancer","funder_award_id":"R01CA233201","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5281897802","display_name":"HuR Targeted Nanotherapy for Lung Cancer","funder_award_id":"R01CA167516","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G854442891","display_name":null,"funder_award_id":"P30 CA225520","funder_id":"https://openalex.org/F4320310179","funder_display_name":"University of Oklahoma"},{"id":"https://openalex.org/G9000049281","display_name":null,"funder_award_id":"CA225520","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000264061","display_name":null,"funder_award_id":"GM103639","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000877612","display_name":"Exosomes as carriers of cancer therapeutics","funder_award_id":"R01CA254192","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000881557","display_name":"Stephenson Cancer Center - Cancer Center Support Grant","funder_award_id":"P30CA225520","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320306480","display_name":"Presbyterian Health Foundation","ror":"https://ror.org/01nbasn20"},{"id":"https://openalex.org/F4320310179","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83"},{"id":"https://openalex.org/F4320315709","display_name":"Tobacco Settlement Endowment Trust","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332607","display_name":"University of Oklahoma Health Sciences Center","ror":"https://ror.org/0457zbj98"},{"id":"https://openalex.org/F4320333795","display_name":"Stephenson Cancer Center","ror":"https://ror.org/02bmcqd02"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4306181562.pdf","grobid_xml":"https://content.openalex.org/works/W4306181562.grobid-xml"},"referenced_works_count":354,"referenced_works":["https://openalex.org/W235945138","https://openalex.org/W254359070","https://openalex.org/W300853132","https://openalex.org/W986753386","https://openalex.org/W1492126200","https://openalex.org/W1492237306","https://openalex.org/W1511669342","https://openalex.org/W1518912170","https://openalex.org/W1545084887","https://openalex.org/W1566677249","https://openalex.org/W1584107383","https://openalex.org/W1608233475","https://openalex.org/W1717645955","https://openalex.org/W1752089945","https://openalex.org/W1820862923","https://openalex.org/W1826852120","https://openalex.org/W1887986120","https://openalex.org/W1907787906","https://openalex.org/W1911808035","https://openalex.org/W1965517002","https://openalex.org/W1967167264","https://openalex.org/W1968919723","https://openalex.org/W1969078911","https://openalex.org/W1969905300","https://openalex.org/W1970108031","https://openalex.org/W1972736792","https://openalex.org/W1973397682","https://openalex.org/W1973480874","https://openalex.org/W1975511102","https://openalex.org/W1976238769","https://openalex.org/W1977145129","https://openalex.org/W1977218170","https://openalex.org/W1977429742","https://openalex.org/W1977629626","https://openalex.org/W1978124642","https://openalex.org/W1978947011","https://openalex.org/W1980144864","https://openalex.org/W1980534599","https://openalex.org/W1981650365","https://openalex.org/W1982443445","https://openalex.org/W1982476634","https://openalex.org/W1982684918","https://openalex.org/W1984705747","https://openalex.org/W1989504358","https://openalex.org/W1990539408","https://openalex.org/W1995128552","https://openalex.org/W1996283740","https://openalex.org/W1998116314","https://openalex.org/W1999776725","https://openalex.org/W2000117535","https://openalex.org/W2000162145","https://openalex.org/W2000341255","https://openalex.org/W2001513844","https://openalex.org/W2002595212","https://openalex.org/W2003478746","https://openalex.org/W2003756264","https://openalex.org/W2004451132","https://openalex.org/W2004662257","https://openalex.org/W2004851542","https://openalex.org/W2005176113","https://openalex.org/W2005558505","https://openalex.org/W2006437549","https://openalex.org/W2008932845","https://openalex.org/W2009462679","https://openalex.org/W2009845901","https://openalex.org/W2010852376","https://openalex.org/W2011253545","https://openalex.org/W2012112428","https://openalex.org/W2014209078","https://openalex.org/W2014593047","https://openalex.org/W2014708467","https://openalex.org/W2019928317","https://openalex.org/W2020911849","https://openalex.org/W2023532020","https://openalex.org/W2024010247","https://openalex.org/W2024216102","https://openalex.org/W2030051678","https://openalex.org/W2030714059","https://openalex.org/W2032042016","https://openalex.org/W2032863945","https://openalex.org/W2033489247","https://openalex.org/W2034502973","https://openalex.org/W2036995683","https://openalex.org/W2039041285","https://openalex.org/W2039143648","https://openalex.org/W2040885133","https://openalex.org/W2041081715","https://openalex.org/W2042556780","https://openalex.org/W2043915025","https://openalex.org/W2044824066","https://openalex.org/W2045342567","https://openalex.org/W2045632759","https://openalex.org/W2045925560","https://openalex.org/W2046100110","https://openalex.org/W2046792302","https://openalex.org/W2047346696","https://openalex.org/W2047664934","https://openalex.org/W2047713688","https://openalex.org/W2048255587","https://openalex.org/W2049462796","https://openalex.org/W2052973047","https://openalex.org/W2054394510","https://openalex.org/W2054630268","https://openalex.org/W2056406429","https://openalex.org/W2056443428","https://openalex.org/W2057271684","https://openalex.org/W2058953427","https://openalex.org/W2059796196","https://openalex.org/W2060850139","https://openalex.org/W2065387333","https://openalex.org/W2066234893","https://openalex.org/W2069994852","https://openalex.org/W2071958575","https://openalex.org/W2072954540","https://openalex.org/W2074634070","https://openalex.org/W2076627833","https://openalex.org/W2077091701","https://openalex.org/W2080986274","https://openalex.org/W2082078734","https://openalex.org/W2083960841","https://openalex.org/W2085555782","https://openalex.org/W2086536239","https://openalex.org/W2089854613","https://openalex.org/W2090703970","https://openalex.org/W2091488826","https://openalex.org/W2092078270","https://openalex.org/W2092718815","https://openalex.org/W2092759184","https://openalex.org/W2095157964","https://openalex.org/W2097257853","https://openalex.org/W2098016561","https://openalex.org/W2098297062","https://openalex.org/W2100163552","https://openalex.org/W2100468603","https://openalex.org/W2102430149","https://openalex.org/W2102982658","https://openalex.org/W2103374010","https://openalex.org/W2104957429","https://openalex.org/W2106625506","https://openalex.org/W2108090987","https://openalex.org/W2110002004","https://openalex.org/W2110439394","https://openalex.org/W2113508481","https://openalex.org/W2114160973","https://openalex.org/W2114801789","https://openalex.org/W2115670698","https://openalex.org/W2116445108","https://openalex.org/W2119703555","https://openalex.org/W2119802952","https://openalex.org/W2120777670","https://openalex.org/W2121583448","https://openalex.org/W2122599809","https://openalex.org/W2123737072","https://openalex.org/W2124213396","https://openalex.org/W2124255030","https://openalex.org/W2124766044","https://openalex.org/W2125043493","https://openalex.org/W2125460615","https://openalex.org/W2127876070","https://openalex.org/W2128209214","https://openalex.org/W2130036151","https://openalex.org/W2130287530","https://openalex.org/W2132295996","https://openalex.org/W2134052952","https://openalex.org/W2134424067","https://openalex.org/W2136159122","https://openalex.org/W2141381043","https://openalex.org/W2143858946","https://openalex.org/W2143942514","https://openalex.org/W2144088824","https://openalex.org/W2146169914","https://openalex.org/W2146416818","https://openalex.org/W2146998614","https://openalex.org/W2147863515","https://openalex.org/W2148417009","https://openalex.org/W2152445360","https://openalex.org/W2153095847","https://openalex.org/W2153825225","https://openalex.org/W2155432224","https://openalex.org/W2157277499","https://openalex.org/W2157502876","https://openalex.org/W2157840751","https://openalex.org/W2159871027","https://openalex.org/W2160532161","https://openalex.org/W2161011316","https://openalex.org/W2162930641","https://openalex.org/W2163107196","https://openalex.org/W2163939306","https://openalex.org/W2165178850","https://openalex.org/W2165781226","https://openalex.org/W2165806251","https://openalex.org/W2166842799","https://openalex.org/W2170078083","https://openalex.org/W2170849399","https://openalex.org/W2175961264","https://openalex.org/W2216001724","https://openalex.org/W2231236206","https://openalex.org/W2280016334","https://openalex.org/W2285541813","https://openalex.org/W2291209850","https://openalex.org/W2318125498","https://openalex.org/W2333547858","https://openalex.org/W2340295145","https://openalex.org/W2341857169","https://openalex.org/W2342398096","https://openalex.org/W2344774066","https://openalex.org/W2345969280","https://openalex.org/W2407531000","https://openalex.org/W2416081551","https://openalex.org/W2418255697","https://openalex.org/W2418418689","https://openalex.org/W2444184208","https://openalex.org/W2467076016","https://openalex.org/W2472500434","https://openalex.org/W2477719030","https://openalex.org/W2485667397","https://openalex.org/W2509153611","https://openalex.org/W2513898207","https://openalex.org/W2517290979","https://openalex.org/W2521390122","https://openalex.org/W2522409468","https://openalex.org/W2525348210","https://openalex.org/W2525446808","https://openalex.org/W2527660600","https://openalex.org/W2528875185","https://openalex.org/W2530453716","https://openalex.org/W2537974699","https://openalex.org/W2553755721","https://openalex.org/W2555871987","https://openalex.org/W2565349538","https://openalex.org/W2566575894","https://openalex.org/W2579100713","https://openalex.org/W2584218507","https://openalex.org/W2584254370","https://openalex.org/W2599276599","https://openalex.org/W2603213989","https://openalex.org/W2605818487","https://openalex.org/W2605980370","https://openalex.org/W2606669462","https://openalex.org/W2621066222","https://openalex.org/W2652154361","https://openalex.org/W2695589886","https://openalex.org/W2699729855","https://openalex.org/W2724166000","https://openalex.org/W2725043720","https://openalex.org/W2725733926","https://openalex.org/W2726313327","https://openalex.org/W2734989022","https://openalex.org/W2739870478","https://openalex.org/W2742512275","https://openalex.org/W2743641223","https://openalex.org/W2745147187","https://openalex.org/W2748564011","https://openalex.org/W2749722012","https://openalex.org/W2750530161","https://openalex.org/W2754846502","https://openalex.org/W2756363936","https://openalex.org/W2756634225","https://openalex.org/W2765386082","https://openalex.org/W2769280193","https://openalex.org/W2771247031","https://openalex.org/W2775867587","https://openalex.org/W2782411240","https://openalex.org/W2782602358","https://openalex.org/W2783890003","https://openalex.org/W2784958513","https://openalex.org/W2785329615","https://openalex.org/W2787166852","https://openalex.org/W2788397742","https://openalex.org/W2789956212","https://openalex.org/W2790732335","https://openalex.org/W2791403577","https://openalex.org/W2801454076","https://openalex.org/W2804311499","https://openalex.org/W2806242678","https://openalex.org/W2807931555","https://openalex.org/W2809229380","https://openalex.org/W2889210641","https://openalex.org/W2889271227","https://openalex.org/W2898185118","https://openalex.org/W2898774052","https://openalex.org/W2899716463","https://openalex.org/W2901313212","https://openalex.org/W2901861413","https://openalex.org/W2908003276","https://openalex.org/W2911120459","https://openalex.org/W2912245607","https://openalex.org/W2912631813","https://openalex.org/W2913769190","https://openalex.org/W2917724292","https://openalex.org/W2918532348","https://openalex.org/W2923023971","https://openalex.org/W2923090623","https://openalex.org/W2932844691","https://openalex.org/W2939398224","https://openalex.org/W2947329869","https://openalex.org/W2949626630","https://openalex.org/W2952105231","https://openalex.org/W2957608739","https://openalex.org/W2960027376","https://openalex.org/W2960563220","https://openalex.org/W2969516501","https://openalex.org/W2986752244","https://openalex.org/W2988451562","https://openalex.org/W2995302866","https://openalex.org/W2995354482","https://openalex.org/W2995953990","https://openalex.org/W2997657154","https://openalex.org/W2998094044","https://openalex.org/W3008388902","https://openalex.org/W3010659583","https://openalex.org/W3010700839","https://openalex.org/W3025174127","https://openalex.org/W3027048395","https://openalex.org/W3031127341","https://openalex.org/W3038818544","https://openalex.org/W3041157841","https://openalex.org/W3043489078","https://openalex.org/W3047086344","https://openalex.org/W3087311660","https://openalex.org/W3091472338","https://openalex.org/W3092583403","https://openalex.org/W3098263827","https://openalex.org/W3106930452","https://openalex.org/W3108794039","https://openalex.org/W3111642970","https://openalex.org/W3125275699","https://openalex.org/W3126427614","https://openalex.org/W3139433309","https://openalex.org/W3158463440","https://openalex.org/W3165143074","https://openalex.org/W3169818427","https://openalex.org/W3179450541","https://openalex.org/W3187838163","https://openalex.org/W3200323187","https://openalex.org/W3207074037","https://openalex.org/W3207450601","https://openalex.org/W3210615301","https://openalex.org/W3213834237","https://openalex.org/W3215777951","https://openalex.org/W4200212774","https://openalex.org/W4210641096","https://openalex.org/W4213118725","https://openalex.org/W4213203946","https://openalex.org/W4213356901","https://openalex.org/W4225565073","https://openalex.org/W6629988080","https://openalex.org/W6633919919","https://openalex.org/W6704535917","https://openalex.org/W6758386031","https://openalex.org/W6774725773","https://openalex.org/W6787508247","https://openalex.org/W6808639711","https://openalex.org/W7140267905"],"related_works":["https://openalex.org/W345076137","https://openalex.org/W3087311660","https://openalex.org/W4391133086","https://openalex.org/W2960027376","https://openalex.org/W4388835782","https://openalex.org/W1977145129","https://openalex.org/W4214860682","https://openalex.org/W3128611965","https://openalex.org/W4322485121","https://openalex.org/W4392626593"],"abstract_inverted_index":{"Traditionally":[0],"majority":[1],"of":[2,17,35,48,62,92,121,146,156,161],"eukaryotic":[3],"gene":[4,49],"expression":[5,16,50,70,91,126],"is":[6],"influenced":[7],"by":[8],"transcriptional":[9],"and":[10,26,42,51,59,65,95,113,123,153,169,173],"post-transcriptional":[11,46],"events.":[12],"Alterations":[13],"in":[14,45,68,88,98,118,127,150,165],"the":[15,90,159],"proteins":[18,30,36],"that":[19,37],"act":[20],"post-transcriptionally":[21],"can":[22,73],"affect":[23],"cellular":[24,53],"signaling":[25],"homeostasis.":[27],"RNA":[28],"binding":[29],"(RBPs)":[31],"are":[32,43],"a":[33],"family":[34,112],"specifically":[38],"bind":[39],"to":[40,75],"RNAs":[41],"involved":[44,97,149],"regulation":[47],"important":[52,86],"processes":[54],"such":[55,104],"as":[56,105,181],"cell":[57],"differentiation":[58],"metabolism.":[60],"Deregulation":[61],"RNA-RBP":[63],"interactions":[64],"any":[66],"changes":[67],"RBP":[69],"or":[71],"function":[72],"lead":[74],"various":[76,99,119],"diseases":[77],"including":[78,163],"cancer.":[79],"In":[80,139],"cancer":[81,128,137,151,167,186],"cells,":[82],"RBPs":[83,103,148,176],"play":[84,115],"an":[85,132,144],"role":[87,160],"regulating":[89],"tumor":[93],"suppressors":[94],"oncoproteins":[96],"cell-signaling":[100],"pathways.":[101],"Several":[102],"HuR,":[106,164],"AUF1,":[107],"RBM38,":[108],"LIN28,":[109],"RBM24,":[110],"tristetrapolin":[111],"Musashi":[114],"critical":[116],"roles":[117],"types":[120],"cancers":[122],"their":[124,154],"aberrant":[125],"cells":[129],"makes":[130],"them":[131],"attractive":[133],"therapeutic":[134,182],"target":[135,183],"for":[136,184],"treatment.":[138],"this":[140],"review":[141],"we":[142],"provide":[143],"overview":[145],"i).":[147],"progression":[152,168],"mechanism":[155],"action":[157],"ii).":[158],"RBPs,":[162],"breast":[166,185],"DNA":[170],"damage":[171],"response":[172],"iii).":[174],"explore":[175],"with":[177],"emphasis":[178],"on":[179],"HuR":[180],"therapy.":[187]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":25},{"year":2024,"cited_by_count":23},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-10-14T00:00:00"}
