{"id":"https://openalex.org/W4304205457","doi":"https://doi.org/10.1136/jnis-2022-019130","title":"Safety and efficacy of intensive systolic blood pressure lowering after successful endovascular therapy: a post hoc analysis of the BP TARGET trial","display_name":"Safety and efficacy of intensive systolic blood pressure lowering after successful endovascular therapy: a post hoc analysis of the BP TARGET trial","publication_year":2022,"publication_date":"2022-10-11","ids":{"openalex":"https://openalex.org/W4304205457","doi":"https://doi.org/10.1136/jnis-2022-019130","pmid":"https://pubmed.ncbi.nlm.nih.gov/36220337"},"language":"en","primary_location":{"id":"doi:10.1136/jnis-2022-019130","doi":"https://doi.org/10.1136/jnis-2022-019130","is_oa":false,"landing_page_url":"https://doi.org/10.1136/jnis-2022-019130","pdf_url":null,"source":{"id":"https://openalex.org/S66405466","display_name":"Journal of NeuroInterventional Surgery","issn_l":"1759-8478","issn":["1759-8478","1759-8486"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of NeuroInterventional Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063636629","display_name":"Mohammad Anadani","orcid":"https://orcid.org/0000-0002-7813-2949","observed_orcids":["https://orcid.org/0000-0002-7813-2949"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohammad Anadani","raw_affiliation_strings":["Neurosurgery, Medical University of South Carolina, Charleston, SC, USA"],"raw_orcid":"https://orcid.org/0000-0002-7813-2949","affiliations":[{"raw_affiliation_string":"Neurosurgery, Medical University of South Carolina, Charleston, SC, USA","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049635906","display_name":"Benjamin Ma\u00efer","orcid":"https://orcid.org/0000-0003-3993-1024","observed_orcids":["https://orcid.org/0000-0003-3993-1024"]},"institutions":[{"id":"https://openalex.org/I4210122116","display_name":"Fondation Ophtalmologique Adolphe de Rothschild","ror":"https://ror.org/02mdxv534","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210122116"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Benjamin Maier","raw_affiliation_strings":["Department of Interventional Neuroradiology, Adolphe de Rothschild Ophthalmological Foundation, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Neuroradiology, Adolphe de Rothschild Ophthalmological Foundation, Paris, France","institution_ids":["https://openalex.org/I4210122116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018010330","display_name":"Simon Escalard","orcid":"https://orcid.org/0000-0003-1306-1008","observed_orcids":["https://orcid.org/0000-0003-1306-1008"]},"institutions":[{"id":"https://openalex.org/I4210090185","display_name":"H\u00f4pital Rothschild","ror":"https://ror.org/009kb8w74","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210090185","https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Simon Escalard","raw_affiliation_strings":["Departement of Interventional Neuroradiology, Fondation Rothschild Hospital, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departement of Interventional Neuroradiology, Fondation Rothschild Hospital, Paris, France","institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013990412","display_name":"Julien Labreuche","orcid":"https://orcid.org/0000-0002-3384-0423","observed_orcids":["https://orcid.org/0000-0002-3384-0423"]},"institutions":[{"id":"https://openalex.org/I2279609970","display_name":"Universit\u00e9 de Lille","ror":"https://ror.org/02kzqn938","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970"]},{"id":"https://openalex.org/I3018718406","display_name":"Centre Hospitalier Universitaire de Lille","ror":"https://ror.org/02ppyfa04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3018718406"]},{"id":"https://openalex.org/I4387155751","display_name":"Evaluation des technologies de sant\u00e9 et des pratiques m\u00e9dicales","ror":"https://ror.org/01qygwc68","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2279609970","https://openalex.org/I3018718406","https://openalex.org/I4387155751"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Julien Labreuche","raw_affiliation_strings":["Univ. Lille, CHU Lille, ULR 2694-METRICS, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Lille, CHU Lille, ULR 2694-METRICS, Lille, France","institution_ids":["https://openalex.org/I2279609970","https://openalex.org/I3018718406","https://openalex.org/I4387155751"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054587412","display_name":"Adam de Havenon","orcid":"https://orcid.org/0000-0001-8178-8597","observed_orcids":["https://orcid.org/0000-0001-8178-8597"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam de Havenon","raw_affiliation_strings":["Department of Neurology, Yale University, New Haven, Connecticut, USA"],"raw_orcid":"https://orcid.org/0000-0001-8178-8597","affiliations":[{"raw_affiliation_string":"Department of Neurology, Yale University, New Haven, Connecticut, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034286418","display_name":"Candice Sabben","orcid":"https://orcid.org/0000-0003-1721-2694","observed_orcids":["https://orcid.org/0000-0003-1721-2694"]},"institutions":[{"id":"https://openalex.org/I4210090185","display_name":"H\u00f4pital Rothschild","ror":"https://ror.org/009kb8w74","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210090185","https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Candice Sabben","raw_affiliation_strings":["Department of Neurology, Fondation Rothschild Hospital, paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Fondation Rothschild Hospital, paris, France","institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090096595","display_name":"Bertrand Lapergue","orcid":"https://orcid.org/0000-0002-8993-2175","observed_orcids":["https://orcid.org/0000-0002-8993-2175"]},"institutions":[{"id":"https://openalex.org/I4210156825","display_name":"H\u00f4pital Foch","ror":"https://ror.org/058td2q88","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210156825"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bertrand Lapergue","raw_affiliation_strings":["Hospital Foch, Suresnes, \u00cele-de-France, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Foch, Suresnes, \u00cele-de-France, France","institution_ids":["https://openalex.org/I4210156825"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020824375","display_name":"Eva A. Mistry","orcid":"https://orcid.org/0000-0002-7426-3650","observed_orcids":["https://orcid.org/0000-0002-7426-3650"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eva A Mistry","raw_affiliation_strings":["Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019973522","display_name":"Benjamin Gory","orcid":"https://orcid.org/0000-0001-8424-4464","observed_orcids":["https://orcid.org/0000-0001-8424-4464","https://orcid.org/0000-0003-1186-3656"]},"institutions":[{"id":"https://openalex.org/I4210100260","display_name":"Centre Hospitalier R\u00e9gional et Universitaire de Nancy","ror":"https://ror.org/016ncsr12","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100260"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Benjamin Gory","raw_affiliation_strings":["Department of Diagnostic and Interventional Neuroradiology, CHRU Nancy, Nancy, Lorraine, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic and Interventional Neuroradiology, CHRU Nancy, Nancy, Lorraine, France","institution_ids":["https://openalex.org/I4210100260"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034122925","display_name":"Alejandro M Spiotta","orcid":"https://orcid.org/0000-0002-7142-5538","observed_orcids":["https://orcid.org/0000-0002-7142-5538"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alejandro M Spiotta","raw_affiliation_strings":["Department of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina, USA","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038541072","display_name":"S\u00e9bastien Richard","orcid":"https://orcid.org/0000-0002-0945-5656","observed_orcids":["https://orcid.org/0000-0002-0945-5656"]},"institutions":[{"id":"https://openalex.org/I4210100260","display_name":"Centre Hospitalier R\u00e9gional et Universitaire de Nancy","ror":"https://ror.org/016ncsr12","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100260"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S\u00e9bastien Richard","raw_affiliation_strings":["Neurology Stroke Unit, University Hospital Centre Nancy, Nancy, France"],"raw_orcid":"https://orcid.org/0000-0002-0945-5656","affiliations":[{"raw_affiliation_string":"Neurology Stroke Unit, University Hospital Centre Nancy, Nancy, France","institution_ids":["https://openalex.org/I4210100260"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078825588","display_name":"Igor Sibon","orcid":"https://orcid.org/0000-0002-1171-4215","observed_orcids":["https://orcid.org/0000-0002-1171-4215"]},"institutions":[{"id":"https://openalex.org/I3018323443","display_name":"Centre Hospitalier Universitaire de Bordeaux","ror":"https://ror.org/01hq89f96","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3018323443"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Igor Sibon","raw_affiliation_strings":["CHU de Bordeaux, Bordeaux, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHU de Bordeaux, Bordeaux, France","institution_ids":["https://openalex.org/I3018323443"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048720974","display_name":"Jean\u2010Philippe D\u00e9silles","orcid":"https://orcid.org/0000-0001-8395-6312","observed_orcids":["https://orcid.org/0000-0001-8395-6312"]},"institutions":[{"id":"https://openalex.org/I4210122116","display_name":"Fondation Ophtalmologique Adolphe de Rothschild","ror":"https://ror.org/02mdxv534","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210122116"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Philippe Desilles","raw_affiliation_strings":["Fondation Ophtalmologique Adolphe de Rothschild, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondation Ophtalmologique Adolphe de Rothschild, Paris, France","institution_ids":["https://openalex.org/I4210122116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086707201","display_name":"Rapha\u00ebl Blanc","orcid":"https://orcid.org/0000-0002-3975-3865","observed_orcids":["https://orcid.org/0000-0002-3975-3865","https://orcid.org/0000-0002-0086-8614"]},"institutions":[{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Raphael Blanc","raw_affiliation_strings":["Department of Interventional Neuroradiology, Fondation Rothschild, Paris, \u00cele-de-France, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Interventional Neuroradiology, Fondation Rothschild, Paris, \u00cele-de-France, France","institution_ids":["https://openalex.org/I4210127304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058666169","display_name":"Michel Piotin","orcid":"https://orcid.org/0000-0002-1354-4328","observed_orcids":["https://orcid.org/0000-0002-1354-4328"]},"institutions":[{"id":"https://openalex.org/I4210090185","display_name":"H\u00f4pital Rothschild","ror":"https://ror.org/009kb8w74","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210090185","https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Michel Piotin","raw_affiliation_strings":["Departement of Interventional Neuroradiology, Fondation Rothschild Hospital, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departement of Interventional Neuroradiology, Fondation Rothschild Hospital, Paris, France","institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057038228","display_name":"Mika\u00ebl Mazighi","orcid":"https://orcid.org/0000-0003-0911-8999","observed_orcids":["https://orcid.org/0000-0003-0911-8999"]},"institutions":[{"id":"https://openalex.org/I4210090185","display_name":"H\u00f4pital Rothschild","ror":"https://ror.org/009kb8w74","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210090185","https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210111631","display_name":"H\u00f4pital Fernand-Widal","ror":"https://ror.org/01zkyzz15","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210111631"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]},{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Mika\u00ebl Mazighi","raw_affiliation_strings":["Departement of Interventional Neuroradiology, Fondation Rothschild Hospital, Paris, France","Department of Neurology, GH Lariboisiere Fernand-Widal, Paris, France"],"raw_orcid":"https://orcid.org/0000-0003-0911-8999","affiliations":[{"raw_affiliation_string":"Departement of Interventional Neuroradiology, Fondation Rothschild Hospital, Paris, France","institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"]},{"raw_affiliation_string":"Department of Neurology, GH Lariboisiere Fernand-Widal, Paris, France","institution_ids":["https://openalex.org/I4210111631","https://openalex.org/I4210119095"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5057038228"],"corresponding_institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210111631","https://openalex.org/I4210119095","https://openalex.org/I4210127304"],"apc_list":null,"apc_paid":null,"fwci":0.1425,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.44478212,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"15","issue":"e1","first_page":"e142","last_page":"e147"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-ischemic-stroke","display_name":"acute ischemic stroke","score":0.9309999942779541},{"id":"https://openalex.org/keywords/endovascular-treatment","display_name":"endovascular treatment","score":0.9359999895095825},{"id":"https://openalex.org/keywords/intraparenchymal-hemorrhage","display_name":"intraparenchymal hemorrhage","score":0.9390000104904175},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.6869999766349792},{"id":"https://openalex.org/keywords/intravenous-thrombolysis","display_name":"intravenous thrombolysis","score":0.8930000066757202},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.5260000228881836},{"id":"https://openalex.org/keywords/recanalization","display_name":"recanalization","score":0.7260000109672546},{"id":"https://openalex.org/keywords/occlusion-location","display_name":"occlusion location","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.95048987865448},{"id":"https://openalex.org/C67761136","wikidata":"https://www.wikidata.org/wiki/Q2105849","display_name":"Post-hoc analysis","level":2,"score":0.8690069913864136},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7328779697418213},{"id":"https://openalex.org/C2992886853","wikidata":"https://www.wikidata.org/wiki/Q18381816","display_name":"Post hoc","level":2,"score":0.5823354125022888},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.41864609718322754},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4176541566848755},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.36797353625297546},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.35413986444473267},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33831897377967834},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.33541250228881836}],"mesh":[{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D057510","descriptor_name":"Endovascular Procedures","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1136/jnis-2022-019130","doi":"https://doi.org/10.1136/jnis-2022-019130","is_oa":false,"landing_page_url":"https://doi.org/10.1136/jnis-2022-019130","pdf_url":null,"source":{"id":"https://openalex.org/S66405466","display_name":"Journal of NeuroInterventional Surgery","issn_l":"1759-8478","issn":["1759-8478","1759-8486"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of NeuroInterventional Surgery","raw_type":"journal-article"},{"id":"pmid:36220337","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36220337","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurointerventional surgery","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04554285v1","doi":null,"is_oa":false,"landing_page_url":"https://lilloa.hal.science/hal-04554285","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Neurointerventional Surgery, 2022, Journal of Neurointerventional Surgery, ⟨10.1136/jnis-2022-019130⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:open-archive.highwire.org:neurintsurg:15/e1/e142","doi":null,"is_oa":false,"landing_page_url":"http://jnis.bmj.com/cgi/content/short/15/e1/e142","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:orbi.ulg.ac.be:2268/327123","doi":null,"is_oa":false,"landing_page_url":"https://orbi.uliege.be/handle/2268/327123","pdf_url":null,"source":{"id":"https://openalex.org/S4306400651","display_name":"Open Repository and Bibliography (University of Li\u00e8ge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I157674565","host_organization_name":"University of Li\u00e8ge","host_organization_lineage":["https://openalex.org/I157674565"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of NeuroInterventional Surgery, 15 (e1), e142 - e147 (2023-09)","raw_type":"http://purl.org/coar/resource_type/c_6501"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5471845620","display_name":null,"funder_award_id":"NCT03160677","funder_id":"https://openalex.org/F4320308007","funder_display_name":"Target Corporation"}],"funders":[{"id":"https://openalex.org/F4320308007","display_name":"Target Corporation","ror":"https://ror.org/05mkyac79"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W2021806767","https://openalex.org/W2022417869","https://openalex.org/W2095459189","https://openalex.org/W2104852105","https://openalex.org/W2147537676","https://openalex.org/W2153200583","https://openalex.org/W2620784009","https://openalex.org/W2726995814","https://openalex.org/W2906973732","https://openalex.org/W2963274253","https://openalex.org/W2988732543","https://openalex.org/W2993175382","https://openalex.org/W2998957896","https://openalex.org/W3012027895","https://openalex.org/W3036269319","https://openalex.org/W3083295686","https://openalex.org/W3084803525","https://openalex.org/W3133993978","https://openalex.org/W3135686458","https://openalex.org/W3163782056","https://openalex.org/W3212381039","https://openalex.org/W3214305484","https://openalex.org/W4200210060"],"related_works":["https://openalex.org/W4210627283","https://openalex.org/W3133993978","https://openalex.org/W4210593077","https://openalex.org/W4393382679","https://openalex.org/W4210334879","https://openalex.org/W7160422201","https://openalex.org/W4307728974","https://openalex.org/W3216769246","https://openalex.org/W4403838393","https://openalex.org/W4390841966"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,132,202],"Safety":[2],"and":[3,127,183,221,233,252],"Efficacy":[4],"of":[5,61,84,89,105,122,125,175,185,192,198,204,214,217,228],"Intensive":[6],"Blood":[7],"Pressure":[8],"Lowering":[9],"after":[10,31],"Successful":[11],"Endovascular":[12],"Therapy":[13],"in":[14,151,163,244],"Acute":[15],"Ischaemic":[16],"Stroke":[17],"(BP":[18],"TARGET)":[19],"trial":[20,65],"demonstrated":[21],"no":[22],"benefit":[23,146,239],"from":[24,147,240],"intensive":[25,148,193,229,241],"systolic":[26],"blood":[27,45,73,119],"pressure":[28,46,74],"(SBP)":[29],"treatment":[30,47,75,150,195,207,243],"successful":[32],"reperfusion":[33],"with":[34,95,129,180],"endovascular":[35],"therapy.":[36],"However,":[37],"it":[38],"remains":[39],"unknown":[40],"if":[41,69],"the":[42,62,70,106,190,199,226],"response":[43,71],"to":[44,67,72,158,169],"is":[48,76,100,249],"modified":[49,77,210,225],"by":[50,78,211],"other":[51],"factors.":[52],"OBJECTIVE:":[53],"To":[54],"carry":[55],"out":[56],"a":[57,101,143,236],"post":[58,102],"hoc":[59,103],"analysis":[60,104],"BP":[63,107],"TARGET":[64,108],"data":[66],"determine":[68],"factors":[79],"such":[80],"as":[81],"age,":[82,117,212],"history":[83,124,184,216],"hypertension,":[85,126,218],"recanalization":[86],"status,":[87],"location":[88,174,213],"occlusion,":[90,123,176],"diabetes,":[91,118],"hyperglycemia,":[92],"or":[93],"pretreatment":[94,128,179],"intravenous":[96,130,181,219],"thrombolysis.":[97,131],"METHODS:":[98],"This":[99,247],"trial.":[109],"Patients":[110],"were":[111],"divided":[112],"into":[113],"groups":[114],"based":[115],"on":[116,196],"glucose,":[120],"site":[121],"primary":[133],"outcome":[134],"was":[135,142,208,235],"any":[136,197],"intraparenchymal":[137],"hemorrhage.":[138],"RESULTS:":[139],"=0.041).":[140],"There":[141],"trend":[144,237],"towards":[145,238],"SBP":[149,194,205,230,242],"diabetic":[152,245],"patients":[153,165],"(OR=2.81;":[154],"95%":[155,167],"CI":[156],"0.88":[157],"8.88;":[159],"p=0.08)":[160],"but":[161],"not":[162,188,209],"non-diabetic":[164],"(OR=0.75;":[166],"0.45":[168],"126;":[170],"p":[171],"0.28).":[172],"Age,":[173],"admission":[177,222],"SBP,":[178],"thrombolysis,":[182,220],"hypertension":[186],"did":[187],"modify":[189],"effect":[191,203,227],"outcomes.":[200],"CONCLUSION:":[201],"lowering":[206,231],"occlusion":[215],"SBP.":[223],"Diabetes":[224],"treatment,":[232],"there":[234],"patients.":[246],"finding":[248],"hypothesis":[250],"generating":[251],"requires":[253],"further":[254],"validation.":[255]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2022-10-11T00:00:00"}