{"id":"https://openalex.org/W4303628080","doi":"https://doi.org/10.3390/covid2100100","title":"Effect of Cold Atmospheric Plasma on SARS-CoV-2 Inactivation: A Pilot Study in the Hospital Environment","display_name":"Effect of Cold Atmospheric Plasma on SARS-CoV-2 Inactivation: A Pilot Study in the Hospital Environment","publication_year":2022,"publication_date":"2022-09-30","ids":{"openalex":"https://openalex.org/W4303628080","doi":"https://doi.org/10.3390/covid2100100"},"language":"en","primary_location":{"id":"doi:10.3390/covid2100100","doi":"https://doi.org/10.3390/covid2100100","is_oa":true,"landing_page_url":"https://doi.org/10.3390/covid2100100","pdf_url":"https://www.mdpi.com/2673-8112/2/10/100/pdf?version=1666243475","source":{"id":"https://openalex.org/S4210226090","display_name":"COVID","issn_l":"2673-8112","issn":["2673-8112"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"COVID","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2673-8112/2/10/100/pdf?version=1666243475","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072045577","display_name":"Konstantinos Loizou","orcid":"https://orcid.org/0000-0003-0355-6162","observed_orcids":["https://orcid.org/0000-0003-0355-6162"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Constantinos Loizou","raw_affiliation_strings":["EMBIO Diagnostics Ltd., 2018 Nicosia, Cyprus"],"raw_orcid":"https://orcid.org/0000-0003-0355-6162","affiliations":[{"raw_affiliation_string":"EMBIO Diagnostics Ltd., 2018 Nicosia, Cyprus","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054599645","display_name":"Volha Kniazeva","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Volha Kniazeva","raw_affiliation_strings":["R.SC. Real Scientists Cyprus Ltd., 4101 Limassol, Cyprus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"R.SC. Real Scientists Cyprus Ltd., 4101 Limassol, Cyprus","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078837890","display_name":"Theofylaktos Apostolou","orcid":"https://orcid.org/0000-0002-2087-8860","observed_orcids":["https://orcid.org/0000-0002-2087-8860"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Theofylaktos Apostolou","raw_affiliation_strings":["EMBIO Diagnostics Ltd., 2018 Nicosia, Cyprus"],"raw_orcid":"https://orcid.org/0000-0002-2087-8860","affiliations":[{"raw_affiliation_string":"EMBIO Diagnostics Ltd., 2018 Nicosia, Cyprus","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Alexander Kornev","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexander Kornev","raw_affiliation_strings":["R.SC. Real Scientists Cyprus Ltd., 4101 Limassol, Cyprus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"R.SC. Real Scientists Cyprus Ltd., 4101 Limassol, Cyprus","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081561064","display_name":"Serhei Kostevitch","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Serhei Kostevitch","raw_affiliation_strings":["R.SC. Real Scientists Cyprus Ltd., 4101 Limassol, Cyprus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"R.SC. Real Scientists Cyprus Ltd., 4101 Limassol, Cyprus","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049676169","display_name":"Evgeny Roslyakov","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Evgeny Roslyakov","raw_affiliation_strings":["R.SC. Real Scientists Cyprus Ltd., 4101 Limassol, Cyprus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"R.SC. Real Scientists Cyprus Ltd., 4101 Limassol, Cyprus","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112879511","display_name":"Costas S. Constantinou","orcid":"https://orcid.org/0009-0003-2987-617X","observed_orcids":["https://orcid.org/0009-0003-2987-617X"]},"institutions":[{"id":"https://openalex.org/I2800486594","display_name":"Nicosia General Hospital","ror":"https://ror.org/056v1sx90","country_code":"CY","type":"healthcare","lineage":["https://openalex.org/I2800486594","https://openalex.org/I4210137065"]}],"countries":["CY"],"is_corresponding":false,"raw_author_name":"Costas Constantinou","raw_affiliation_strings":["Nicosia General Hospital, 2029 Nicosia, Cyprus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nicosia General Hospital, 2029 Nicosia, Cyprus","institution_ids":["https://openalex.org/I2800486594"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016403324","display_name":"Linos Hadjihannas","orcid":"https://orcid.org/0009-0009-4334-4050","observed_orcids":["https://orcid.org/0009-0009-4334-4050"]},"institutions":[{"id":"https://openalex.org/I2800486594","display_name":"Nicosia General Hospital","ror":"https://ror.org/056v1sx90","country_code":"CY","type":"healthcare","lineage":["https://openalex.org/I2800486594","https://openalex.org/I4210137065"]}],"countries":["CY"],"is_corresponding":false,"raw_author_name":"Linos Hadjihannas","raw_affiliation_strings":["Nicosia General Hospital, 2029 Nicosia, Cyprus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nicosia General Hospital, 2029 Nicosia, Cyprus","institution_ids":["https://openalex.org/I2800486594"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5054599645","https://openalex.org/A5072045577"],"corresponding_institution_ids":[],"apc_list":{"value":1000,"currency":"CHF","value_usd":1047},"apc_paid":{"value":1000,"currency":"CHF","value_usd":1047},"fwci":0.7791,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.63181806,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"2","issue":"10","first_page":"1396","last_page":"1404"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10642","display_name":"Atmospheric-Pressure Plasma Applications","score":0.9218999743461609,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10642","display_name":"Atmospheric-Pressure Plasma Applications","score":0.9218999743461609,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10990","display_name":"Infection Control and Ventilation","score":0.0706000030040741,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12916","display_name":"COVID-19 impact on air quality","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2306","display_name":"Global and Planetary Change"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cold-atmospheric-plasma","display_name":"cold atmospheric plasma","score":1.0},{"id":"https://openalex.org/keywords/sars-cov-2-inactivation","display_name":"SARS-CoV-2 inactivation","score":0.9610000252723694},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.703000009059906},{"id":"https://openalex.org/keywords/airborne-virus-transmission","display_name":"airborne virus transmission","score":0.6460000276565552},{"id":"https://openalex.org/keywords/ion-emitters","display_name":"ion emitters","score":0.7710000276565552},{"id":"https://openalex.org/keywords/hospital-wards","display_name":"hospital wards","score":0.5260000228881836},{"id":"https://openalex.org/keywords/hospital-discharge","display_name":"hospital discharge","score":0.33899998664855957}],"concepts":[{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.7190240621566772},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.5561926364898682},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5267350673675537},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.5147411823272705},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.49316900968551636},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.3821560740470886},{"id":"https://openalex.org/C39432304","wikidata":"https://www.wikidata.org/wiki/Q188847","display_name":"Environmental science","level":0,"score":0.36923158168792725},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.3295276165008545},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2890770435333252},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18228858709335327},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.12779629230499268},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.10643771290779114},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.08932799100875854},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/covid2100100","doi":"https://doi.org/10.3390/covid2100100","is_oa":true,"landing_page_url":"https://doi.org/10.3390/covid2100100","pdf_url":"https://www.mdpi.com/2673-8112/2/10/100/pdf?version=1666243475","source":{"id":"https://openalex.org/S4210226090","display_name":"COVID","issn_l":"2673-8112","issn":["2673-8112"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"COVID","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/covid2100100","doi":"https://doi.org/10.3390/covid2100100","is_oa":true,"landing_page_url":"https://doi.org/10.3390/covid2100100","pdf_url":"https://www.mdpi.com/2673-8112/2/10/100/pdf?version=1666243475","source":{"id":"https://openalex.org/S4210226090","display_name":"COVID","issn_l":"2673-8112","issn":["2673-8112"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"COVID","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4303628080.pdf","grobid_xml":"https://content.openalex.org/works/W4303628080.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1766381468","https://openalex.org/W2029176742","https://openalex.org/W2058465738","https://openalex.org/W2095070917","https://openalex.org/W2102517635","https://openalex.org/W2121597163","https://openalex.org/W2404733084","https://openalex.org/W2553593772","https://openalex.org/W2739820821","https://openalex.org/W2793306696","https://openalex.org/W2948344040","https://openalex.org/W3005652542","https://openalex.org/W3013531488","https://openalex.org/W3015266612","https://openalex.org/W3018334611","https://openalex.org/W3026051701","https://openalex.org/W3085656071","https://openalex.org/W3091928367","https://openalex.org/W3092655831","https://openalex.org/W3115676058","https://openalex.org/W3148521889","https://openalex.org/W3149156279","https://openalex.org/W3165361457","https://openalex.org/W3187335143","https://openalex.org/W3197810858","https://openalex.org/W3210275226","https://openalex.org/W4200360642","https://openalex.org/W4206990971","https://openalex.org/W4213457829","https://openalex.org/W4220735306"],"related_works":["https://openalex.org/W6903686921","https://openalex.org/W4312692340","https://openalex.org/W7122924179","https://openalex.org/W4294344136","https://openalex.org/W3187335143","https://openalex.org/W3101830981","https://openalex.org/W6922455749","https://openalex.org/W4200220661","https://openalex.org/W4362679556","https://openalex.org/W4389207599"],"abstract_inverted_index":{"The":[0,140,176],"spread":[1,187],"of":[2,43,78,92,142],"the":[3,18,38,41,55,76,83,87,111,123,127,131,134,146,149,157,165,171],"new":[4,34],"coronavirus":[5,186],"SARS-CoV-2":[6],"has":[7,54],"substantial":[8],"social,":[9],"health,":[10],"and":[11,50,122,160,191],"economic":[12],"impacts.":[13],"High":[14],"viral":[15,84],"load":[16,85],"in":[17,20,40,86,148,156,164,170,188],"air":[19,42],"hospitals":[21],"poses":[22],"a":[23,33],"risk":[24],"to":[25,74,138],"medical":[26],"personnel.":[27],"Cold":[28],"atmospheric":[29],"plasma":[30],"(CAP)":[31],"is":[32],"technology":[35],"based":[36],"on":[37],"emission":[39],"reactive":[44],"species,":[45],"neutral":[46],"particles,":[47],"UV":[48],"radiation,":[49],"electromagnetic":[51],"field.":[52],"CAP":[53,79,183],"potential":[56],"as":[57],"an":[58,64,114],"antiviral":[59],"agent.":[60],"In":[61],"this":[62],"study,":[63],"80-day":[65],"clinical":[66,177],"trial":[67,178],"took":[68],"place":[69],"at":[70],"Nicosia":[71],"General":[72],"Hospital":[73],"evaluate":[75],"application":[77],"devices":[80],"for":[81,101],"lowering":[82],"COVID":[88,135],"rooms.":[89],"A":[90],"total":[91],"284":[93],"indoor":[94],"environment":[95],"samples":[96],"were":[97,104],"tested":[98],"by":[99],"RT-PCR,":[100],"which":[102],"9":[103],"positive":[105],"(~3%":[106],"Positive":[107],"Rate).":[108],"After":[109],"analyzing":[110],"initial":[112],"results,":[113],"ion":[115],"emitter":[116],"was":[117,152],"paired":[118],"with":[119],"each":[120],"patient,":[121],"results":[124],"showed":[125],"that":[126,181],"method":[128],"could":[129],"eliminate":[130],"virus":[132,194],"from":[133,145],"wards":[136],"up":[137],"100%.":[139],"number":[141],"patients":[143,163],"discharged":[144],"hospital":[147,189],"ionizer":[150,166],"group":[151,167],"4.8%":[153],"higher":[154],"than":[155],"non-ionizer":[158],"group,":[159],"45%":[161],"fewer":[162],"who":[168],"remained":[169],"rooms":[172],"required":[173],"oxygen":[174],"support.":[175],"shows":[179],"evidence":[180],"composite":[182],"can":[184],"decrease":[185],"environments":[190],"potentially":[192],"prevent":[193],"transmission.":[195]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2022-10-08T00:00:00"}