{"id":"https://openalex.org/W4300588952","doi":"https://doi.org/10.1097/00004714-198912000-00002","title":"Dietary Restriction, Tyramine, and the Use of Monoamine Oxidase Inhibitors","display_name":"Dietary Restriction, Tyramine, and the Use of Monoamine Oxidase Inhibitors","publication_year":1989,"publication_date":"1989-12-01","ids":{"openalex":"https://openalex.org/W4300588952","doi":"https://doi.org/10.1097/00004714-198912000-00002","mag":"1984871706","pmid":"https://pubmed.ncbi.nlm.nih.gov/2592589"},"language":"en","primary_location":{"id":"doi:10.1097/00004714-198912000-00002","doi":"https://doi.org/10.1097/00004714-198912000-00002","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00004714-198912000-00002","pdf_url":null,"source":{"id":"https://openalex.org/S76849566","display_name":"Journal of Clinical Psychopharmacology","issn_l":"0271-0749","issn":["0271-0749","1533-712X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Psychopharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069880992","display_name":"Kenneth I. Shulman","orcid":"https://orcid.org/0000-0002-6558-5770","observed_orcids":["https://orcid.org/0000-0002-6558-5770"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"KENNETH I. SHULMAN","raw_affiliation_strings":["Departments of Psychiatry and Pharmacy, University of Toronto, Snnnybrook Medical Centre, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Psychiatry and Pharmacy, University of Toronto, Snnnybrook Medical Centre, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057832019","display_name":"Scott E. Walker","orcid":"https://orcid.org/0000-0002-1762-427X","observed_orcids":["https://orcid.org/0000-0002-1762-427X"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"SCOTT E. WALKER","raw_affiliation_strings":["Departments of Psychiatry and Pharmacy, University of Toronto, Snnnybrook Medical Centre, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Psychiatry and Pharmacy, University of Toronto, Snnnybrook Medical Centre, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059979692","display_name":"SUSAN MACKENZIE","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"SUSAN MACKENZIE","raw_affiliation_strings":["Departments of Psychiatry and Pharmacy, University of Toronto, Snnnybrook Medical Centre, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Psychiatry and Pharmacy, University of Toronto, Snnnybrook Medical Centre, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091604935","display_name":"Knowles Sandra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"SANDRA KNOWLES","raw_affiliation_strings":["Departments of Psychiatry and Pharmacy, University of Toronto, Snnnybrook Medical Centre, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Psychiatry and Pharmacy, University of Toronto, Snnnybrook Medical Centre, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I185261750"],"apc_list":null,"apc_paid":null,"fwci":0.3231,"has_fulltext":false,"cited_by_count":69,"citation_normalized_percentile":{"value":0.53383295,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"9","issue":"6","first_page":"397???402","last_page":"397???402"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11924","display_name":"Polyamine Metabolism and Applications","score":0.7515000104904175,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11924","display_name":"Polyamine Metabolism and Applications","score":0.7515000104904175,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.03700000047683716,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.02419999986886978,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dietary-restriction","display_name":"dietary restriction","score":0.8740000128746033},{"id":"https://openalex.org/keywords/tyramine","display_name":"tyramine","score":0.9480000138282776},{"id":"https://openalex.org/keywords/monoamine-oxidase-inhibitors","display_name":"monoamine oxidase inhibitors","score":0.9990000128746033},{"id":"https://openalex.org/keywords/food-safety","display_name":"food safety","score":0.5820000171661377},{"id":"https://openalex.org/keywords/aged-cheese","display_name":"aged cheese","score":0.9319999814033508},{"id":"https://openalex.org/keywords/marmite","display_name":"marmite","score":0.8019999861717224},{"id":"https://openalex.org/keywords/sauerkraut","display_name":"sauerkraut","score":0.9810000061988831},{"id":"https://openalex.org/keywords/spirit","display_name":"alcoholic beverages","score":0.8510000109672546},{"id":"https://openalex.org/keywords/drug-interactions","display_name":"drug interactions","score":0.5170000195503235}],"concepts":[{"id":"https://openalex.org/C2776077682","wikidata":"https://www.wikidata.org/wiki/Q165930","display_name":"Tyramine","level":2,"score":0.9723570346832275},{"id":"https://openalex.org/C2776024655","wikidata":"https://www.wikidata.org/wiki/Q410867","display_name":"Monoamine oxidase","level":3,"score":0.8750697374343872},{"id":"https://openalex.org/C55952523","wikidata":"https://www.wikidata.org/wiki/Q3014419","display_name":"Wine","level":2,"score":0.5923771858215332},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.5657854080200195},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.41060835123062134},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3594258427619934},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.324579656124115},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.32047978043556213},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.1787208616733551}],"mesh":[{"descriptor_ui":"D005504","descriptor_name":"Food Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D008996","descriptor_name":"Monoamine Oxidase Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D008996","descriptor_name":"Monoamine Oxidase Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D014439","descriptor_name":"Tyramine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D014439","descriptor_name":"Tyramine","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1097/00004714-198912000-00002","doi":"https://doi.org/10.1097/00004714-198912000-00002","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00004714-198912000-00002","pdf_url":null,"source":{"id":"https://openalex.org/S76849566","display_name":"Journal of Clinical Psychopharmacology","issn_l":"0271-0749","issn":["0271-0749","1533-712X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Psychopharmacology","raw_type":"journal-article"},{"id":"pmid:2592589","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2592589","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical psychopharmacology","raw_type":"Journal Article"},{"id":"mag:1984871706","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2592589","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2334709760","https://openalex.org/W1275227374","https://openalex.org/W193065994","https://openalex.org/W2893335423","https://openalex.org/W2182236286","https://openalex.org/W203031526","https://openalex.org/W2088719192","https://openalex.org/W4253972074","https://openalex.org/W1998408883","https://openalex.org/W2116057877"],"abstract_inverted_index":{"The":[0],"aim":[1],"of":[2,30,47,54,95],"this":[3],"study":[4],"is":[5],"to":[6,43,57,85],"provide":[7],"clearer":[8],"guidelines":[9],"for":[10,17],"rational,":[11],"safe,":[12],"and":[13,72,97],"practical":[14],"dietary":[15],"restriction":[16],"use":[18],"with":[19,38],"monoamine":[20],"oxidase":[21],"inhibitors.":[22],"Tyramine":[23],"levels":[24,46,94],"were":[25],"assayed":[26],"in":[27,82],"over":[28],"100":[29],"the":[31],"controversial":[32],"foods":[33,55],"that":[34],"have":[35],"been":[36],"associated":[37],"hypertensive":[39],"reactions":[40],"or":[41],"reported":[42],"contain":[44,91],"high":[45,93],"tyramine.":[48],"Only":[49],"a":[50],"very":[51],"limited":[52],"number":[53],"appear":[56,84],"require":[58,98],"absolute":[59],"restriction.":[60],"These":[61],"include":[62],"all":[63],"aged":[64,89],"cheeses,":[65],"concentrated":[66],"yeast":[67],"extracts":[68],"(e.g.,":[69],"Marmite),":[70],"sauerkraut,":[71],"broad":[73],"bean":[74],"pods.":[75],"Alcoholic":[76],"beverages,":[77],"including":[78],"Chianti":[79],"wine":[80],"consumed":[81],"moderation,":[83],"be":[86],"safe.":[87],"Some":[88],"meats":[90],"relatively":[92],"tyramine":[96],"closer":[99],"investigation.":[100]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-10-03T00:00:00"}