{"id":"https://openalex.org/W4298129233","doi":"https://doi.org/10.2307/3284013","title":"Protection against Murine Cerebral Malaria by Dietary-Induced Oxidative Stress","display_name":"Protection against Murine Cerebral Malaria by Dietary-Induced Oxidative Stress","publication_year":1995,"publication_date":"1995-02-01","ids":{"openalex":"https://openalex.org/W4298129233","doi":"https://doi.org/10.2307/3284013","mag":"1980672627","pmid":"https://pubmed.ncbi.nlm.nih.gov/7876987"},"language":"en","primary_location":{"id":"doi:10.2307/3284013","doi":"https://doi.org/10.2307/3284013","is_oa":false,"landing_page_url":"https://doi.org/10.2307/3284013","pdf_url":null,"source":{"id":"https://openalex.org/S31573680","display_name":"Journal of Parasitology","issn_l":"0022-3395","issn":["0022-3395","1937-2345"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310316431","host_organization_name":"American Society of Parasitologists","host_organization_lineage":["https://openalex.org/P4310316431"],"host_organization_lineage_names":["American Society of Parasitologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Parasitology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113994832","display_name":"Orville A. Levander","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Orville A. Levander","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075775349","display_name":"Rosa Fontela","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rosa Fontela","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051130566","display_name":"Virginia C. Morris","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Virginia C. Morris","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5113870937","display_name":"Arba L. Ager","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arba L. Ager","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4659,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.89993919,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"81","issue":"1","first_page":"99","last_page":"99"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12178","display_name":"Bird parasitology and diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerebral-malaria","display_name":"cerebral malaria","score":0.9850000143051147},{"id":"https://openalex.org/keywords/plasmodium-berghei-anka","display_name":"Plasmodium berghei ANKA","score":0.9160000085830688},{"id":"https://openalex.org/keywords/menhaden-oil","display_name":"menhaden oil","score":0.8980000019073486},{"id":"https://openalex.org/keywords/vitamin-e-deficiency","display_name":"vitamin E deficiency","score":0.9520000219345093},{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.5879999995231628},{"id":"https://openalex.org/keywords/probucol","display_name":"probucol","score":0.8119999766349792},{"id":"https://openalex.org/keywords/nutritional-therapy","display_name":"nutritional therapy","score":0.4440000057220459}],"concepts":[{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.8155144453048706},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7970514297485352},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.7013318538665771},{"id":"https://openalex.org/C2908793570","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Cerebral Malaria","level":4,"score":0.5934482216835022},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.46004632115364075},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3615756332874298},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.32142195105552673},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.29383569955825806},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1519961953163147},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14987152814865112}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000821","descriptor_name":"Animal Feed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005395","descriptor_name":"Fish Oils","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005395","descriptor_name":"Fish Oils","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008808","descriptor_name":"Mice, Inbred CBA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010655","descriptor_name":"Phenylenediamines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010655","descriptor_name":"Phenylenediamines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010962","descriptor_name":"Plasmodium berghei","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011341","descriptor_name":"Probucol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D011341","descriptor_name":"Probucol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014811","descriptor_name":"Vitamin E Deficiency","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D016779","descriptor_name":"Malaria, Cerebral","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D016779","descriptor_name":"Malaria, Cerebral","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016779","descriptor_name":"Malaria, Cerebral","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.2307/3284013","doi":"https://doi.org/10.2307/3284013","is_oa":false,"landing_page_url":"https://doi.org/10.2307/3284013","pdf_url":null,"source":{"id":"https://openalex.org/S31573680","display_name":"Journal of Parasitology","issn_l":"0022-3395","issn":["0022-3395","1937-2345"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310316431","host_organization_name":"American Society of Parasitologists","host_organization_lineage":["https://openalex.org/P4310316431"],"host_organization_lineage_names":["American Society of Parasitologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Parasitology","raw_type":"journal-article"},{"id":"pmid:7876987","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7876987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of parasitology","raw_type":"Journal Article"},{"id":"mag:1980672627","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7876987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.5365999937057495,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W55075274","https://openalex.org/W103502324","https://openalex.org/W1034587186","https://openalex.org/W1671539701","https://openalex.org/W1891450090","https://openalex.org/W1895462365","https://openalex.org/W1978446484","https://openalex.org/W1993470718","https://openalex.org/W2004515700","https://openalex.org/W2010698686","https://openalex.org/W2015073860","https://openalex.org/W2016388562","https://openalex.org/W2042558624","https://openalex.org/W2053389978","https://openalex.org/W2069415529","https://openalex.org/W2070679789","https://openalex.org/W2082243209","https://openalex.org/W2094478720","https://openalex.org/W2121554370","https://openalex.org/W2130563538","https://openalex.org/W2152209378","https://openalex.org/W2163567334","https://openalex.org/W2323870293","https://openalex.org/W2327515496"],"related_works":["https://openalex.org/W2010698686","https://openalex.org/W2163567334","https://openalex.org/W2152209378","https://openalex.org/W2124699814","https://openalex.org/W7100141625","https://openalex.org/W1991752959","https://openalex.org/W2782708830","https://openalex.org/W1993470718","https://openalex.org/W2130563538","https://openalex.org/W4389089927"],"abstract_inverted_index":{"Feeding":[0],"20%":[1],"(w/w)":[2,51],"menhaden-fish":[3],"oil":[4,53,112],"in":[5,145],"a":[6,43,67,119,141],"standard":[7],"laboratory":[8],"chow":[9],"diet":[10,48,64,85,92],"for":[11,34],"4":[12],"wk":[13],"partially":[14],"protected":[15],"CBA/CaJ":[16],"mice":[17],"from":[18],"the":[19,72,81,91,110,124,128,156],"central":[20],"nervous":[21],"system":[22],"consequences":[23],"of":[24,80,99,134,155],"infection":[25],"with":[26,93,97,149],"Plasmodium":[27],"berghei":[28],"(ANKA).":[29],"Full":[30],"protection":[31],"(complete":[32],"survival":[33],"14":[35],"days":[36],"postinfection)":[37],"could":[38,86],"be":[39,87,140],"obtained":[40],"by":[41,89,117],"feeding":[42],"purified":[44,59],"pro-oxidant":[45,60,150],"vitamin":[46,94],"E-deficient":[47],"containing":[49],"4%":[50],"menhaden":[52],"(MO":[54],"-":[55,62,83],"VE":[56,63,84],"diet).":[57],"The":[58,77],"MO":[61,82],"also":[65],"exerted":[66],"pronounced":[68],"suppressive":[69],"effect":[70,79,116],"against":[71],"parasite":[73],"(depressed":[74],"6-day":[75],"parasitemias).":[76],"anitmalarial":[78],"prevented":[88],"supplementing":[90],"E":[95],"or":[96,104,130],"either":[98],"2":[100],"synthetic":[101],"antioxidants,":[102],"N,N'-diphenyl-p-phenylenediamine":[103],"probucol.":[105],"These":[106],"results":[107],"suggest":[108],"that":[109],"fish":[111],"exerts":[113],"its":[114],"antimalarial":[115],"imposing":[118],"dietary-induced":[120],"oxidative":[121,136],"stress":[122,137],"on":[123],"infected":[125],"host":[126,135],"erythrocyte,":[127],"parasite,":[129],"both.":[131],"Nutritional":[132],"manipulation":[133],"status":[138],"may":[139],"useful":[142],"adjunct":[143],"therapy":[144],"patients":[146],"undergoing":[147],"treatment":[148],"antimalarials":[151],"such":[152],"as":[153],"drugs":[154],"qinghaosu":[157],"family.":[158]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2022-10-01T00:00:00"}