{"id":"https://openalex.org/W4297994972","doi":"https://doi.org/10.1016/j.euroneuro.2022.09.002","title":"The role of metformin as a treatment for neuropsychiatric illness","display_name":"The role of metformin as a treatment for neuropsychiatric illness","publication_year":2022,"publication_date":"2022-09-30","ids":{"openalex":"https://openalex.org/W4297994972","doi":"https://doi.org/10.1016/j.euroneuro.2022.09.002","pmid":"https://pubmed.ncbi.nlm.nih.gov/36191545"},"language":"en","primary_location":{"id":"doi:10.1016/j.euroneuro.2022.09.002","doi":"https://doi.org/10.1016/j.euroneuro.2022.09.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.euroneuro.2022.09.002","pdf_url":null,"source":{"id":"https://openalex.org/S168041952","display_name":"European Neuropsychopharmacology","issn_l":"0924-977X","issn":["0924-977X","1873-7862"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Neuropsychopharmacology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/journal_contribution/The_role_of_metformin_as_a_treatment_for_neuropsychiatric_illness/21352659","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042812626","display_name":"Seetal Dodd","orcid":"https://orcid.org/0000-0002-7918-4636","observed_orcids":["https://orcid.org/0000-0002-7918-4636"]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]},{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Seetal Dodd","raw_affiliation_strings":["Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia; Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia. Electronic address: seetald@barwonhealth.org.au","Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia","Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia"],"raw_orcid":"https://orcid.org/0000-0002-7918-4636","affiliations":[{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia; Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia. Electronic address: seetald@barwonhealth.org.au","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539","https://openalex.org/I165779595"]},{"raw_affiliation_string":"Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539"]},{"raw_affiliation_string":"Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005870070","display_name":"Luba Sominsky","orcid":"https://orcid.org/0000-0002-0674-8824","observed_orcids":["https://orcid.org/0000-0002-0674-8824"]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]},{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]},{"id":"https://openalex.org/I2799712879","display_name":"Geelong Hospital","ror":"https://ror.org/00jrpxe15","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203","https://openalex.org/I2799712879"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Luba Sominsky","raw_affiliation_strings":["Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Barwon Health Laboratory, University Hospital Geelong, Barwon Health, VIC, Australia","Barwon Health Laboratory, University Hospital Geelong, Barwon Health, VIC, Australia","Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Barwon Health Laboratory, University Hospital Geelong, Barwon Health, VIC, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539","https://openalex.org/I2799712879"]},{"raw_affiliation_string":"Barwon Health Laboratory, University Hospital Geelong, Barwon Health, VIC, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I2799712879"]},{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001271340","display_name":"Dan J. Siskind","orcid":"https://orcid.org/0000-0002-2072-9216","observed_orcids":["https://orcid.org/0000-0002-2072-9216"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]},{"id":"https://openalex.org/I4210089726","display_name":"Metro South Health","ror":"https://ror.org/016gd3115","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2801244131","https://openalex.org/I4210089726"]},{"id":"https://openalex.org/I4210105605","display_name":"Queensland Centre for Mental Health Research","ror":"https://ror.org/017zhda45","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2801244131","https://openalex.org/I4210105605"]},{"id":"https://openalex.org/I4405258507","display_name":"Addiction and Mental Health Services - MSH","ror":"https://ror.org/00s894y88","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2801244131","https://openalex.org/I4210089726","https://openalex.org/I4405258507"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Dan Siskind","raw_affiliation_strings":["Metro South Addiction and Mental Health Service, MIRT, Level 2, 228 Logan Rd, Woolloongabba, Brisbane, Qld 4102, Australia University of Queensland School of Clinical Medicine, Brisbane, Australia Queensland Centre for Mental Health Research, Brisbane, Australia; Faculty of Medicine, University of Queensland, Brisbane, Australia","Faculty of Medicine, University of Queensland, Brisbane, Australia","Metro South Addiction and Mental Health Service, MIRT, Level 2, 228 Logan Rd, Woolloongabba, Brisbane, Qld 4102, Australia University of Queensland School of Clinical Medicine, Brisbane, Australia Queensland Centre for Mental Health Research, Brisbane, Australia"],"raw_orcid":"https://orcid.org/0000-0002-2072-9216","affiliations":[{"raw_affiliation_string":"Metro South Addiction and Mental Health Service, MIRT, Level 2, 228 Logan Rd, Woolloongabba, Brisbane, Qld 4102, Australia University of Queensland School of Clinical Medicine, Brisbane, Australia Queensland Centre for Mental Health Research, Brisbane, Australia; Faculty of Medicine, University of Queensland, Brisbane, Australia","institution_ids":["https://openalex.org/I165143802","https://openalex.org/I4210105605","https://openalex.org/I4405258507"]},{"raw_affiliation_string":"Faculty of Medicine, University of Queensland, Brisbane, Australia","institution_ids":["https://openalex.org/I165143802"]},{"raw_affiliation_string":"Metro South Addiction and Mental Health Service, MIRT, Level 2, 228 Logan Rd, Woolloongabba, Brisbane, Qld 4102, Australia University of Queensland School of Clinical Medicine, Brisbane, Australia Queensland Centre for Mental Health Research, Brisbane, Australia","institution_ids":["https://openalex.org/I165143802","https://openalex.org/I4210089726","https://openalex.org/I4210105605","https://openalex.org/I4405258507"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023365501","display_name":"Chiara C. Bortolasci","orcid":"https://orcid.org/0000-0002-0794-6363","observed_orcids":["https://orcid.org/0000-0002-0794-6363"]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]},{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Chiara C Bortolasci","raw_affiliation_strings":["Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014656654","display_name":"Andre Ferrer Carvalho","orcid":"https://orcid.org/0000-0002-2500-5671","observed_orcids":["https://orcid.org/0000-0002-2500-5671"]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]},{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Andre F. Carvalho","raw_affiliation_strings":["Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032880777","display_name":"Michael H. J. Maes","orcid":"https://orcid.org/0000-0002-2012-871X","observed_orcids":["https://orcid.org/0000-0002-2012-871X","https://orcid.org/0000-0003-2178-7589"]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]},{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Michael Maes","raw_affiliation_strings":["Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036731916","display_name":"Adam J. Walker","orcid":"https://orcid.org/0000-0002-5399-1245","observed_orcids":["https://orcid.org/0000-0002-5399-1245"]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]},{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Adam J. Walker","raw_affiliation_strings":["Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia"],"raw_orcid":"https://orcid.org/0000-0002-5399-1245","affiliations":[{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070000043","display_name":"Ken R. Walder","orcid":"https://orcid.org/0000-0002-6758-4763","observed_orcids":["https://orcid.org/0000-0002-6758-4763"]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]},{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Ken Walder","raw_affiliation_strings":["Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia"],"raw_orcid":"https://orcid.org/0000-0002-6758-4763","affiliations":[{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081014409","display_name":"Alison Ruth Yung","orcid":"https://orcid.org/0000-0002-0401-9791","observed_orcids":["https://orcid.org/0000-0002-0401-9791"]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]},{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["AU","GB"],"is_corresponding":false,"raw_author_name":"Alison R Yung","raw_affiliation_strings":["Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia; School of Health Sciences, University of Manchester, Manchester, United Kingdom","Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia","Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","School of Health Sciences, University of Manchester, Manchester, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-0401-9791","affiliations":[{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia; School of Health Sciences, University of Manchester, Manchester, United Kingdom","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539","https://openalex.org/I165779595","https://openalex.org/I28407311"]},{"raw_affiliation_string":"Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539"]},{"raw_affiliation_string":"School of Health Sciences, University of Manchester, Manchester, United Kingdom","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057787833","display_name":"Lana J. Williams","orcid":"https://orcid.org/0000-0002-1377-1272","observed_orcids":["https://orcid.org/0000-0002-1377-1272"]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]},{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Lana J. Williams","raw_affiliation_strings":["Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007257339","display_name":"Hannah Myles","orcid":"https://orcid.org/0000-0003-3411-5693","observed_orcids":["https://orcid.org/0000-0003-3411-5693"]},"institutions":[{"id":"https://openalex.org/I4210120278","display_name":"SA Health","ror":"https://ror.org/01tg7a346","country_code":"AU","type":"government","lineage":["https://openalex.org/I2800277939","https://openalex.org/I4210120278"]},{"id":"https://openalex.org/I5681781","display_name":"The University of Adelaide","ror":"https://ror.org/00892tw58","country_code":"AU","type":"education","lineage":["https://openalex.org/I4405259444","https://openalex.org/I5681781"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Hannah Myles","raw_affiliation_strings":["Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia; Northern Adelaide Mental Health Service, Salisbury, SA, Australia","Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia","Northern Adelaide Mental Health Service, Salisbury, SA, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia; Northern Adelaide Mental Health Service, Salisbury, SA, Australia","institution_ids":["https://openalex.org/I5681781"]},{"raw_affiliation_string":"Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia","institution_ids":["https://openalex.org/I5681781"]},{"raw_affiliation_string":"Northern Adelaide Mental Health Service, Salisbury, SA, Australia","institution_ids":["https://openalex.org/I4210120278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053381101","display_name":"Tayler Watson","orcid":"https://orcid.org/0000-0003-0840-8476","observed_orcids":["https://orcid.org/0000-0003-0840-8476"]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Tayler Watson","raw_affiliation_strings":["Mental Health, Drugs and Alcohol Service, Barwon Health, Geelong VIC, Australia"],"raw_orcid":"https://orcid.org/0000-0003-0840-8476","affiliations":[{"raw_affiliation_string":"Mental Health, Drugs and Alcohol Service, Barwon Health, Geelong VIC, Australia","institution_ids":["https://openalex.org/I132157203"]}]},{"author_position":"last","author":{"id":null,"display_name":"Michael Berk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]},{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Michael Berk","raw_affiliation_strings":["Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia; Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia","Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia","Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia","Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia; Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia; Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"raw_affiliation_string":"Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Deakin University, IMPACT, The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539"]},{"raw_affiliation_string":"Department of Psychiatry, the University of Melbourne, Parkville, VIC, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia","institution_ids":["https://openalex.org/I165779595","https://openalex.org/I242743682"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5042812626"],"corresponding_institution_ids":["https://openalex.org/I132157203","https://openalex.org/I149704539","https://openalex.org/I165779595"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.9124,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.65158018,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"64","issue":null,"first_page":"32","last_page":"43"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.46140000224113464,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.46140000224113464,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.38530001044273376,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.04399999976158142,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metformin","display_name":"metformin","score":1.0},{"id":"https://openalex.org/keywords/drug-repurposing","display_name":"drug repurposing","score":0.9309999942779541},{"id":"https://openalex.org/keywords/neuropsychiatric-disorders","display_name":"neuropsychiatric disorders","score":0.8529999852180481},{"id":"https://openalex.org/keywords/ampk","display_name":"AMPK","score":0.753000020980835},{"id":"https://openalex.org/keywords/blood-glucose-reduction","display_name":"blood glucose reduction","score":0.7749999761581421},{"id":"https://openalex.org/keywords/neuroimmunology","display_name":"neuroimmunology","score":0.8320000171661377},{"id":"https://openalex.org/keywords/neuroplasticity","display_name":"neuroplasticity","score":0.9800000190734863},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7960000038146973},{"id":"https://openalex.org/keywords/nitrosative-stress","display_name":"nitrosative stress","score":0.8700000047683716},{"id":"https://openalex.org/keywords/metabolic-comorbidities","display_name":"metabolic comorbidities","score":0.8180000185966492},{"id":"https://openalex.org/keywords/endocrinology","display_name":"endocrinology","score":0.5960000157356262},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.8190000057220459},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.6919999718666077},{"id":"https://openalex.org/keywords/psychopharmacology","display_name":"psychopharmacology","score":0.8870000243186951}],"concepts":[{"id":"https://openalex.org/C2780323712","wikidata":"https://www.wikidata.org/wiki/Q19484","display_name":"Metformin","level":3,"score":0.9339410066604614},{"id":"https://openalex.org/C103709681","wikidata":"https://www.wikidata.org/wiki/Q1515727","display_name":"Psychopharmacology","level":2,"score":0.6342807412147522},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6323384642601013},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6086517572402954},{"id":"https://openalex.org/C2780124434","wikidata":"https://www.wikidata.org/wiki/Q12357464","display_name":"AMPK","level":4,"score":0.5758435726165771},{"id":"https://openalex.org/C2776674806","wikidata":"https://www.wikidata.org/wiki/Q12135","display_name":"Mental illness","level":3,"score":0.5526590347290039},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.43786340951919556},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.41868436336517334},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.37131381034851074},{"id":"https://openalex.org/C134362201","wikidata":"https://www.wikidata.org/wiki/Q317309","display_name":"Mental health","level":2,"score":0.30339694023132324},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.13514897227287292},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1056266725063324},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.09266626834869385},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09117671847343445},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.euroneuro.2022.09.002","doi":"https://doi.org/10.1016/j.euroneuro.2022.09.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.euroneuro.2022.09.002","pdf_url":null,"source":{"id":"https://openalex.org/S168041952","display_name":"European Neuropsychopharmacology","issn_l":"0924-977X","issn":["0924-977X","1873-7862"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Neuropsychopharmacology","raw_type":"journal-article"},{"id":"pmid:36191545","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36191545","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology","raw_type":"Journal Article"},{"id":"pmh:oai:digital.library.adelaide.edu.au:2440/152225","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2440/152225","pdf_url":null,"source":{"id":"https://openalex.org/S4306401835","display_name":"Adelaide Research & Scholarship (AR&S) (University of Adelaide)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I5681781","host_organization_name":"The University of Adelaide","host_organization_lineage":["https://openalex.org/I5681781"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://doi.org/10.1016/j.euroneuro.2022.09.002","raw_type":"Journal article"},{"id":"pmh:oai:figshare.com:article/21352659","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/The_role_of_metformin_as_a_treatment_for_neuropsychiatric_illness/21352659","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/21352659","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/The_role_of_metformin_as_a_treatment_for_neuropsychiatric_illness/21352659","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":92,"referenced_works":["https://openalex.org/W23780688","https://openalex.org/W185214937","https://openalex.org/W1533842935","https://openalex.org/W1654164926","https://openalex.org/W1721575563","https://openalex.org/W1854257503","https://openalex.org/W1893959718","https://openalex.org/W1909117315","https://openalex.org/W1966805395","https://openalex.org/W1968767676","https://openalex.org/W1984202512","https://openalex.org/W1999881425","https://openalex.org/W2007473119","https://openalex.org/W2017266270","https://openalex.org/W2019017315","https://openalex.org/W2020474316","https://openalex.org/W2029891577","https://openalex.org/W2039304002","https://openalex.org/W2047122869","https://openalex.org/W2050621767","https://openalex.org/W2058677294","https://openalex.org/W2058802517","https://openalex.org/W2064018079","https://openalex.org/W2084049865","https://openalex.org/W2097576923","https://openalex.org/W2113506865","https://openalex.org/W2125306830","https://openalex.org/W2126623223","https://openalex.org/W2128771042","https://openalex.org/W2137293650","https://openalex.org/W2154024784","https://openalex.org/W2161376690","https://openalex.org/W2162361973","https://openalex.org/W2170708988","https://openalex.org/W2188846692","https://openalex.org/W2268421734","https://openalex.org/W2312968642","https://openalex.org/W2406458472","https://openalex.org/W2428885023","https://openalex.org/W2436128242","https://openalex.org/W2474518039","https://openalex.org/W2484520098","https://openalex.org/W2529188573","https://openalex.org/W2572252150","https://openalex.org/W2604753146","https://openalex.org/W2606457199","https://openalex.org/W2609050420","https://openalex.org/W2769466337","https://openalex.org/W2779090429","https://openalex.org/W2802094546","https://openalex.org/W2804795923","https://openalex.org/W2806638867","https://openalex.org/W2900537649","https://openalex.org/W2902912703","https://openalex.org/W2905939204","https://openalex.org/W2907830451","https://openalex.org/W2908827463","https://openalex.org/W2921277338","https://openalex.org/W2925054441","https://openalex.org/W2941499365","https://openalex.org/W2944348781","https://openalex.org/W2947301433","https://openalex.org/W2948900739","https://openalex.org/W2958971346","https://openalex.org/W2964394554","https://openalex.org/W2971940423","https://openalex.org/W2981767691","https://openalex.org/W2985421076","https://openalex.org/W2997621205","https://openalex.org/W3000639965","https://openalex.org/W3007105983","https://openalex.org/W3007281681","https://openalex.org/W3009569400","https://openalex.org/W3018354989","https://openalex.org/W3033359790","https://openalex.org/W3043760418","https://openalex.org/W3086326189","https://openalex.org/W3089092310","https://openalex.org/W3089135006","https://openalex.org/W3111703679","https://openalex.org/W3131407568","https://openalex.org/W3137514586","https://openalex.org/W3138661979","https://openalex.org/W3153610861","https://openalex.org/W3161940807","https://openalex.org/W3163458768","https://openalex.org/W3205249774","https://openalex.org/W4210519941","https://openalex.org/W4211080275","https://openalex.org/W4225314865","https://openalex.org/W4288068670","https://openalex.org/W4297520042"],"related_works":["https://openalex.org/W7171964000","https://openalex.org/W4407034401","https://openalex.org/W3084274097","https://openalex.org/W4313200242","https://openalex.org/W3032395406","https://openalex.org/W7117233621","https://openalex.org/W4288068670","https://openalex.org/W4223421624","https://openalex.org/W7162612633","https://openalex.org/W3169620149"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-10-01T00:00:00"}