{"id":"https://openalex.org/W4297724993","doi":"https://doi.org/10.2147/ott.s3651","title":"Current status of treatment of metastatic colorectal cancer with special reference to cetuximab and elderly patients","display_name":"Current status of treatment of metastatic colorectal cancer with special reference to cetuximab and elderly patients","publication_year":2008,"publication_date":"2008-12-01","ids":{"openalex":"https://openalex.org/W4297724993","doi":"https://doi.org/10.2147/ott.s3651","mag":"2009635875","pmid":"https://pubmed.ncbi.nlm.nih.gov/20616891","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2886318"},"language":"en","primary_location":{"id":"doi:10.2147/ott.s3651","doi":"https://doi.org/10.2147/ott.s3651","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ott.s3651","pdf_url":"https://www.dovepress.com/getfile.php?fileID=4114","source":{"id":"https://openalex.org/S120324992","display_name":"OncoTargets and Therapy","issn_l":"1178-6930","issn":["1178-6930"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OncoTargets and Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/getfile.php?fileID=4114","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068848511","display_name":"Per Pfeiffer","orcid":"https://orcid.org/0000-0002-2925-0586","observed_orcids":["https://orcid.org/0000-0002-2925-0586"]},"institutions":[{"id":"https://openalex.org/I177969490","display_name":"University of Southern Denmark","ror":"https://ror.org/03yrrjy16","country_code":"DK","type":"education","lineage":["https://openalex.org/I177969490"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801498763"]}],"countries":["DK"],"is_corresponding":true,"raw_author_name":"Per Pfeiffer","raw_affiliation_strings":["Department of Oncology, Odense University Hospital, Sdr Boulevard 29, DK -5000 Odense C, Denmark","Department of Oncology , Odense University Hospital . Institute of Clinical Research , University of Southern Denmark. Odense C , Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Odense University Hospital, Sdr Boulevard 29, DK -5000 Odense C, Denmark","institution_ids":["https://openalex.org/I2801498763"]},{"raw_affiliation_string":"Department of Oncology , Odense University Hospital . Institute of Clinical Research , University of Southern Denmark. Odense C , Denmark","institution_ids":["https://openalex.org/I177969490","https://openalex.org/I2801498763"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044982282","display_name":"Qvortrup","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177969490","display_name":"University of Southern Denmark","ror":"https://ror.org/03yrrjy16","country_code":"DK","type":"education","lineage":["https://openalex.org/I177969490"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801498763"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Qvortrup","raw_affiliation_strings":["Department of Oncology, Odense University Hospital. Institute of Clinical Research, University of Southern Denmark. Odense C, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Odense University Hospital. Institute of Clinical Research, University of Southern Denmark. Odense C, Denmark","institution_ids":["https://openalex.org/I177969490","https://openalex.org/I2801498763"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032823171","display_name":"Bjerregaard","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bjerregaard","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5068848511"],"corresponding_institution_ids":["https://openalex.org/I177969490","https://openalex.org/I2801498763"],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":0.0,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"2","issue":null,"first_page":"17","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12064","display_name":"Intraperitoneal and Appendiceal Malignancies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metastatic-colorectal-cancer","display_name":"metastatic colorectal cancer","score":0.9890000224113464},{"id":"https://openalex.org/keywords/cetuximab","display_name":"cetuximab","score":1.0},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.9869999885559082},{"id":"https://openalex.org/keywords/anti-egfr-monoclonal-antibody","display_name":"anti-EGFR monoclonal antibody","score":0.6079999804496765},{"id":"https://openalex.org/keywords/combination-chemotherapy","display_name":"combination chemotherapy","score":0.7720000147819519},{"id":"https://openalex.org/keywords/targeted-therapy","display_name":"targeted therapy","score":0.8119999766349792},{"id":"https://openalex.org/keywords/treatment-related-toxicity","display_name":"treatment toxicity","score":0.6140000224113464},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.796999990940094},{"id":"https://openalex.org/keywords/treatment-selection","display_name":"treatment selection","score":0.42899999022483826}],"concepts":[{"id":"https://openalex.org/C2779998722","wikidata":"https://www.wikidata.org/wiki/Q420296","display_name":"Cetuximab","level":4,"score":0.9923828840255737},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9137569069862366},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.8174327611923218},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6765545606613159},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6446422338485718},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5377943515777588},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5195927619934082},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4655279517173767},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.41419869661331177}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.2147/ott.s3651","doi":"https://doi.org/10.2147/ott.s3651","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ott.s3651","pdf_url":"https://www.dovepress.com/getfile.php?fileID=4114","source":{"id":"https://openalex.org/S120324992","display_name":"OncoTargets and Therapy","issn_l":"1178-6930","issn":["1178-6930"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OncoTargets and Therapy","raw_type":"journal-article"},{"id":"pmid:20616891","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20616891","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OncoTargets and therapy","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2886318","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2886318/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Onco Targets Ther","raw_type":"Text"},{"id":"pmh:oai:sdu.dk:openaire_cris_publications/89e14e70-d7aa-11de-b0fe-000ea68e967b","doi":null,"is_oa":false,"landing_page_url":"https://portal.findresearcher.sdu.dk/da/publications/89e14e70-d7aa-11de-b0fe-000ea68e967b","pdf_url":null,"source":{"id":"https://openalex.org/S4306400423","display_name":"University of Southern Denmark Research Portal (University of Southern Denmark)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177969490","host_organization_name":"University of Southern Denmark","host_organization_lineage":["https://openalex.org/I177969490"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pfeiffer, P, Qvortrup, C & Kroll Bjerregaard, J 2009, 'Current status of treatment of metastatic colorectal cancer with special reference to cetuximab and elderly patients', OncoTargets and Therapy, vol. 2, pp. 17-27.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:212b2e97e42e4dc8a1337f896c79e3b9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/212b2e97e42e4dc8a1337f896c79e3b9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"OncoTargets and Therapy, Vol 2009, Iss default, Pp 17-27 (2008)","raw_type":"article"},{"id":"pmh:oai:dovepress.com/2759","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/current-status-of-treatment-of-metastatic-colorectal-cancer-with-speci-peer-reviewed-article-OTT","pdf_url":null,"source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Review"},{"id":"mag:2009635875","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20616891","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"doi:10.2147/ott.s3651","doi":"https://doi.org/10.2147/ott.s3651","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ott.s3651","pdf_url":"https://www.dovepress.com/getfile.php?fileID=4114","source":{"id":"https://openalex.org/S120324992","display_name":"OncoTargets and Therapy","issn_l":"1178-6930","issn":["1178-6930"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OncoTargets and Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4297724993.pdf","grobid_xml":"https://content.openalex.org/works/W4297724993.grobid-xml"},"referenced_works_count":109,"referenced_works":["https://openalex.org/W1596261235","https://openalex.org/W1847661643","https://openalex.org/W1874410314","https://openalex.org/W1923056904","https://openalex.org/W1939364580","https://openalex.org/W1966872277","https://openalex.org/W1968282664","https://openalex.org/W1971452237","https://openalex.org/W1972729559","https://openalex.org/W1975426795","https://openalex.org/W1976367809","https://openalex.org/W1999250974","https://openalex.org/W2000436105","https://openalex.org/W2003369307","https://openalex.org/W2006824814","https://openalex.org/W2009443603","https://openalex.org/W2017654486","https://openalex.org/W2021585972","https://openalex.org/W2031389016","https://openalex.org/W2033261360","https://openalex.org/W2038033632","https://openalex.org/W2038828905","https://openalex.org/W2039144093","https://openalex.org/W2040287930","https://openalex.org/W2052899264","https://openalex.org/W2053230335","https://openalex.org/W2054614254","https://openalex.org/W2058934913","https://openalex.org/W2061995614","https://openalex.org/W2066375220","https://openalex.org/W2066497136","https://openalex.org/W2069305509","https://openalex.org/W2074473619","https://openalex.org/W2074937425","https://openalex.org/W2078908647","https://openalex.org/W2085705101","https://openalex.org/W2089612100","https://openalex.org/W2090359261","https://openalex.org/W2092861431","https://openalex.org/W2096122707","https://openalex.org/W2097121246","https://openalex.org/W2098223440","https://openalex.org/W2100589633","https://openalex.org/W2100842180","https://openalex.org/W2102601598","https://openalex.org/W2106712365","https://openalex.org/W2106789440","https://openalex.org/W2107601678","https://openalex.org/W2115090138","https://openalex.org/W2115790682","https://openalex.org/W2116781863","https://openalex.org/W2118902065","https://openalex.org/W2120490763","https://openalex.org/W2121368761","https://openalex.org/W2122885616","https://openalex.org/W2124495521","https://openalex.org/W2124531563","https://openalex.org/W2127500959","https://openalex.org/W2128403792","https://openalex.org/W2128447158","https://openalex.org/W2130816987","https://openalex.org/W2133399075","https://openalex.org/W2136055188","https://openalex.org/W2137242191","https://openalex.org/W2137759849","https://openalex.org/W2142564546","https://openalex.org/W2145818888","https://openalex.org/W2146100972","https://openalex.org/W2151595445","https://openalex.org/W2152632692","https://openalex.org/W2155311724","https://openalex.org/W2156700619","https://openalex.org/W2157416388","https://openalex.org/W2158863975","https://openalex.org/W2158997283","https://openalex.org/W2161482321","https://openalex.org/W2162313061","https://openalex.org/W2162315065","https://openalex.org/W2164837623","https://openalex.org/W2165132869","https://openalex.org/W2165164569","https://openalex.org/W2166112130","https://openalex.org/W2168213749","https://openalex.org/W2168377135","https://openalex.org/W2171429059","https://openalex.org/W2172181172","https://openalex.org/W2183739716","https://openalex.org/W2217081518","https://openalex.org/W2227477053","https://openalex.org/W2272586831","https://openalex.org/W2274027958","https://openalex.org/W2312990179","https://openalex.org/W2314927739","https://openalex.org/W2319860625","https://openalex.org/W2325087121","https://openalex.org/W2325130914","https://openalex.org/W2331849216","https://openalex.org/W2341036513","https://openalex.org/W2344396584","https://openalex.org/W2371259918","https://openalex.org/W2410392468","https://openalex.org/W2589823065","https://openalex.org/W2599727572","https://openalex.org/W2619195059","https://openalex.org/W3011151394","https://openalex.org/W4239226594","https://openalex.org/W4253960919","https://openalex.org/W4382359474","https://openalex.org/W4382359689"],"related_works":["https://openalex.org/W2332381564","https://openalex.org/W2125942839","https://openalex.org/W4254167620","https://openalex.org/W2590116100","https://openalex.org/W2328431720","https://openalex.org/W2124039860","https://openalex.org/W2227480549","https://openalex.org/W1987187839","https://openalex.org/W2277954680","https://openalex.org/W2321286369"],"abstract_inverted_index":{"Current":[0],"status":[1],"of":[2,4,23,29,33,52,59,77,98,167,195],"treatment":[3,54],"metastatic":[5,115,214],"colorectal":[6,63,116,215],"cancer":[7,40,64,117],"with":[8,100,106,108,114,121,140,178],"special":[9],"reference":[10],"to":[11,94,128],"cetuximab":[12,81,141,150,170,186],"and":[13,45,133,160,169],"elderly":[14,83,112,152,175,196,207,218],"patients":[15,41,113,120,219],"Per":[16],"Pfeiffer,":[17],"Camilla":[18],"Qvortrup,":[19],"Jon":[20],"K":[21],"BjerregaardDepartment":[22],"Oncology,":[24],"Odense":[25,36],"University":[26,32],"Hospital.":[27],"Institute":[28],"Clinical":[30],"Research,":[31],"Southern":[34],"Denmark.":[35],"C,":[37],"DenmarkPurpose:":[38],"Elderly":[39],"often":[42],"have":[43,86,148,188],"co-morbidities":[44],"other":[46],"characteristics":[47],"that":[48,164,202],"make":[49],"the":[50,75,78,88,92,96,165,205],"selection":[51],"optimal":[53],"more":[55,129],"complex.":[56],"The":[57],"introduction":[58],"targeted":[60],"therapies":[61],"in":[62,82,91,104,138,142,151,173,192,204,211],"has":[65],"further":[66],"complicated":[67],"this":[68],"problem.":[69],"This":[70],"review":[71],"will":[72],"focus":[73,110],"on":[74,111],"role":[76],"EGFR":[79],"antibody":[80],"patients.Methods:":[84],"We":[85],"reviewed":[87],"available":[89,199],"evidence":[90],"literature":[93],"evaluate":[95],"results":[97,209],"therapy":[99],"cetuximab,":[101,217],"alone":[102],"or":[103],"combination":[105,123,139],"chemotherapy,":[107],"a":[109,193],"(mCRC).Results:":[118],"In":[119],"mCRC,":[122],"chemotherapy":[124,168],"prolongs":[125],"median":[126],"survival":[127],"than":[130],"18":[131],"months":[132,137],"even":[134],"around":[135],"24":[136],"selected":[143],"patients.":[144,153,197],"No":[145,184],"prospective":[146,185],"studies":[147,187],"evaluated":[149],"However,":[154,198],"subgroup":[155],"analyses":[156],"from":[157],"randomized":[158],"trials":[159],"retrospective":[161],"analysis":[162],"suggest":[163,201],"efficacy":[166],"is":[171],"maintained":[172],"fit":[174,206],"patients,":[176],"but":[177,181],"slightly":[179],"increased":[180],"acceptable":[182],"toxicity.Conclusion:":[183],"been":[189],"conducted":[190],"solely":[191],"population":[194],"data":[200],"outcomes":[203],"mirror":[208],"observed":[210],"younger":[212],"patients.Keywords:":[213],"cancer,":[216]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-09-30T00:00:00"}