{"id":"https://openalex.org/W4297597600","doi":null,"title":"Detection of circulating PR3-specific B cells in patients with active ANCA-associated vasculitis","display_name":"Detection of circulating PR3-specific B cells in patients with active ANCA-associated vasculitis","publication_year":2019,"publication_date":"2019-06-12","ids":{"openalex":"https://openalex.org/W4297597600"},"language":"en","primary_location":{"id":"pmh:oai:HAL:hal-02149065v1","doi":null,"is_oa":false,"landing_page_url":"https://univ-brest.hal.science/hal-02149065","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"EULAR European Congress of Rheumatology 2019, Jun 2019, Madrid, Spain","raw_type":"info:eu-repo/semantics/conferenceObject"},"volume":null,"type":"conference-paper","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007242477","display_name":"Divi Cornec","orcid":"https://orcid.org/0000-0002-9159-702X","observed_orcids":["https://orcid.org/0000-0002-9159-702X"]},"institutions":[{"id":"https://openalex.org/I4210132604","display_name":"Centre Hospitalier R\u00e9gional Universitaire de Brest","ror":"https://ror.org/03evbwn87","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I154526488","https://openalex.org/I4210105774","https://openalex.org/I4210132604","https://openalex.org/I4210161065"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Cornec, D.","raw_affiliation_strings":["CHU - BREST - Rhumato - CHRU Brest - Service de Rhumatologie (H\u00f4pital de la Cavale Blanche, Boulevard Tanguy Prigent, 29200 Brest  - France)","LBAI - Lymphocytes B, Autoimmunit\u00e9 et Immunoth\u00e9rapies (5 Foch - CHU Morvan - BP 824 - 29609 Brest - France - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHU - BREST - Rhumato - CHRU Brest - Service de Rhumatologie (H\u00f4pital de la Cavale Blanche, Boulevard Tanguy Prigent, 29200 Brest  - France)","institution_ids":["https://openalex.org/I4210132604"]},{"raw_affiliation_string":"LBAI - Lymphocytes B, Autoimmunit\u00e9 et Immunoth\u00e9rapies (5 Foch - CHU Morvan - BP 824 - 29609 Brest - France - France)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022570560","display_name":"Alvise Berti","orcid":"https://orcid.org/0000-0002-7831-921X","observed_orcids":["https://orcid.org/0000-0002-7831-921X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Berti, A","raw_affiliation_strings":["Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108414055","display_name":"Amber M. Hummel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hummel, A.","raw_affiliation_strings":["Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007441721","display_name":"Eva M. Carmona","orcid":"https://orcid.org/0000-0001-9852-8396","observed_orcids":["https://orcid.org/0000-0001-9852-8396"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carmona, E","raw_affiliation_strings":["Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108726564","display_name":"Tobias Peikert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peikert, T","raw_affiliation_strings":["Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113825642","display_name":"C. A. Langford","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Langford, C","raw_affiliation_strings":["Cleveland Clinic (9500 Euclid Avenue, Cleveland, Ohio 44195 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cleveland Clinic (9500 Euclid Avenue, Cleveland, Ohio 44195 - United States)","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082909035","display_name":"Paul A. Monach","orcid":"https://orcid.org/0000-0003-4937-0515","observed_orcids":["https://orcid.org/0000-0003-4937-0515"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Monach, P","raw_affiliation_strings":["BWH - Brigham & Women\u2019s Hospital [Boston] (75 Francis street, Boston MA 02115 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BWH - Brigham & Women\u2019s Hospital [Boston] (75 Francis street, Boston MA 02115 - United States)","institution_ids":["https://openalex.org/I1283280774"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106744504","display_name":"Peter A. Merkel","orcid":"https://orcid.org/0000-0001-9284-7345","observed_orcids":["https://orcid.org/0000-0001-9284-7345"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Merkel, P","raw_affiliation_strings":["University of Pennsylvania (3451 Walnut Street, Philadelphia, PA 19104 | 215-898-5000 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania (3451 Walnut Street, Philadelphia, PA 19104 | 215-898-5000 - United States)","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073621138","display_name":"Philip Seo","orcid":"https://orcid.org/0000-0003-3435-6737","observed_orcids":["https://orcid.org/0000-0003-3435-6737"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Seo, P","raw_affiliation_strings":["Johns Hopkins Hospital (Baltimore, MD - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins Hospital (Baltimore, MD - United States)","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004355994","display_name":"Robert Spiera","orcid":"https://orcid.org/0000-0003-2911-6800","observed_orcids":["https://orcid.org/0000-0003-2911-6800"]},"institutions":[{"id":"https://openalex.org/I1281539108","display_name":"Hospital for Special Surgery","ror":"https://ror.org/03zjqec80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1281539108"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Spiera, R","raw_affiliation_strings":["Hospital for Special Surgery (535 E 70th St, New York, NY 10021, \u00c9tats-Unis - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital for Special Surgery (535 E 70th St, New York, NY 10021, \u00c9tats-Unis - United States)","institution_ids":["https://openalex.org/I1281539108"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113655834","display_name":"E. W. St. Clair","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"St. Clair, E","raw_affiliation_strings":["Duke University Medical Center (2301 Erwin Rd, Durham, NC 27710 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Medical Center (2301 Erwin Rd, Durham, NC 27710 - United States)","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073207965","display_name":"Fernando Custodio Fervenza","orcid":"https://orcid.org/0000-0002-9952-209X","observed_orcids":["https://orcid.org/0000-0002-9952-209X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fervenza, F.","raw_affiliation_strings":["Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060457096","display_name":"Kristina M. Harris","orcid":"https://orcid.org/0000-0002-6957-514X","observed_orcids":["https://orcid.org/0000-0002-6957-514X"]},"institutions":[{"id":"https://openalex.org/I4210094308","display_name":"Immune Tolerance Network","ror":"https://ror.org/00pjnm784","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210094308","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harris, K","raw_affiliation_strings":["Immune Tolerance Network (7500 Old Georgetown Rd, Bethesda, MD 20814. - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immune Tolerance Network (7500 Old Georgetown Rd, Bethesda, MD 20814. - United States)","institution_ids":["https://openalex.org/I4210094308"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Stone, J","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stone, J","raw_affiliation_strings":["Massachusetts General Hospital [Boston] (55 Fruit Street\r\nBoston, MA 02114 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital [Boston] (55 Fruit Street\r\nBoston, MA 02114 - United States)","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111954024","display_name":"J.\u2010O. Pers","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pers, Jo","raw_affiliation_strings":["LBAI - Lymphocytes B, Autoimmunit\u00e9 et Immunoth\u00e9rapies (5 Foch - CHU Morvan - BP 824 - 29609 Brest - France - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LBAI - Lymphocytes B, Autoimmunit\u00e9 et Immunoth\u00e9rapies (5 Foch - CHU Morvan - BP 824 - 29609 Brest - France - France)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063701076","display_name":"Peter Heeringa","orcid":"https://orcid.org/0000-0001-8684-763X","observed_orcids":["https://orcid.org/0000-0001-8684-763X"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Heeringa, P","raw_affiliation_strings":["UMCG - University Medical Center Groningen [Groningen] (PO box 30.001\r\n9700 RB Groningen - Netherlands)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UMCG - University Medical Center Groningen [Groningen] (PO box 30.001\r\n9700 RB Groningen - Netherlands)","institution_ids":["https://openalex.org/I1334415907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002770850","display_name":"Wayel Habib Abdulahad","orcid":"https://orcid.org/0000-0003-3109-4487","observed_orcids":["https://orcid.org/0000-0003-3109-4487"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Abdulahad, W","raw_affiliation_strings":["UMCG - University Medical Center Groningen [Groningen] (PO box 30.001\r\n9700 RB Groningen - Netherlands)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UMCG - University Medical Center Groningen [Groningen] (PO box 30.001\r\n9700 RB Groningen - Netherlands)","institution_ids":["https://openalex.org/I1334415907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012967877","display_name":"Ulrich Specks","orcid":"https://orcid.org/0000-0002-6559-1206","observed_orcids":["https://orcid.org/0000-0002-6559-1206"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Specks, U","raw_affiliation_strings":["Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic [Rochester] (200 First St. SW\r\nRochester, MN 55905 - United States)","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":12,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.55296432,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anca-associated-vasculitis","display_name":"ANCA-associated vasculitis","score":0.9200000166893005},{"id":"https://openalex.org/keywords/circulating-b-cells","display_name":"circulating B cells","score":0.722000002861023},{"id":"https://openalex.org/keywords/anti-proteinase-3-antibodies","display_name":"anti-proteinase 3 antibodies","score":0.6779999732971191},{"id":"https://openalex.org/keywords/autoantibody-testing","display_name":"autoantibody detection","score":0.6859999895095825}],"concepts":[{"id":"https://openalex.org/C2910998276","wikidata":"https://www.wikidata.org/wiki/Q7148839","display_name":"ANCA-Associated Vasculitis","level":4,"score":0.5282950401306152},{"id":"https://openalex.org/C2776015282","wikidata":"https://www.wikidata.org/wiki/Q644318","display_name":"Vasculitis","level":3,"score":0.4777892529964447},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4378594160079956},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4065195620059967},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1595754623413086},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.05317193269729614}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:HAL:hal-02149065v1","doi":null,"is_oa":false,"landing_page_url":"https://univ-brest.hal.science/hal-02149065","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"EULAR European Congress of Rheumatology 2019, Jun 2019, Madrid, Spain","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3009801373","https://openalex.org/W2755529829","https://openalex.org/W2950164262","https://openalex.org/W4297601937","https://openalex.org/W2934898400","https://openalex.org/W2752789881","https://openalex.org/W3204763137","https://openalex.org/W4404405554","https://openalex.org/W4391274753","https://openalex.org/W6886893552"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2022-09-30T00:00:00"}