{"id":"https://openalex.org/W4296908217","doi":"https://doi.org/10.1101/2022.09.19.22280125","title":"Knowledge and attitudes towards thalassemia among university students in Bangladesh","display_name":"Knowledge and attitudes towards thalassemia among university students in Bangladesh","publication_year":2022,"publication_date":"2022-09-20","ids":{"openalex":"https://openalex.org/W4296908217","doi":"https://doi.org/10.1101/2022.09.19.22280125"},"language":"en","primary_location":{"id":"doi:10.1101/2022.09.19.22280125","doi":"https://doi.org/10.1101/2022.09.19.22280125","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2022.09.19.22280125","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2022/09/20/2022.09.19.22280125.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.medrxiv.org/content/medrxiv/early/2022/09/20/2022.09.19.22280125.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109586420","display_name":"Jubayer Hossain","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jubayer Hossain","raw_affiliation_strings":["Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh"],"raw_orcid":"https://orcid.org/0000-0001-9323-4997","affiliations":[{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","institution_ids":[]},{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013812916","display_name":"Syeda Tasneem Towhid","orcid":"https://orcid.org/0000-0001-5168-2572","observed_orcids":["https://orcid.org/0000-0001-5168-2572"]},"institutions":[{"id":"https://openalex.org/I4210125938","display_name":"Jagannath University","ror":"https://ror.org/02c4z7527","country_code":"BD","type":"education","lineage":["https://openalex.org/I4210125938"]}],"countries":["BD"],"is_corresponding":true,"raw_author_name":"Syeda Tasneem Towhid","raw_affiliation_strings":["Department of Microbiology, Jagannath University, 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh"],"raw_orcid":"https://orcid.org/0000-0001-5168-2572","affiliations":[{"raw_affiliation_string":"Department of Microbiology, Jagannath University, 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","institution_ids":["https://openalex.org/I4210125938"]},{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","institution_ids":[]},{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042241068","display_name":"Sabia Sultana","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125938","display_name":"Jagannath University","ror":"https://ror.org/02c4z7527","country_code":"BD","type":"education","lineage":["https://openalex.org/I4210125938"]}],"countries":["BD"],"is_corresponding":false,"raw_author_name":"Sabia Sultana","raw_affiliation_strings":["Department of Microbiology, Jagannath University, 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Jagannath University, 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","institution_ids":["https://openalex.org/I4210125938"]},{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","institution_ids":[]},{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086730004","display_name":"Sumaiya Akter Mukta","orcid":"https://orcid.org/0000-0001-8025-1501","observed_orcids":["https://orcid.org/0000-0001-8025-1501"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sumaiya Akter Mukta","raw_affiliation_strings":["Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh"],"raw_orcid":"https://orcid.org/0000-0001-8025-1501","affiliations":[{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","institution_ids":[]},{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034748688","display_name":"Rubaiya Gulshan","orcid":"https://orcid.org/0000-0002-8247-0932","observed_orcids":["https://orcid.org/0000-0002-8247-0932"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rubaiya Gulshan","raw_affiliation_strings":["Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh"],"raw_orcid":"https://orcid.org/0000-0002-8247-0932","affiliations":[{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","institution_ids":[]},{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016725437","display_name":"Sharif Miah","orcid":"https://orcid.org/0000-0001-5801-3136","observed_orcids":["https://orcid.org/0000-0001-5801-3136"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sharif Miah","raw_affiliation_strings":["Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh"],"raw_orcid":"https://orcid.org/0000-0001-5801-3136","affiliations":[{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-10 Chittaranjan Avenue, Dhaka-1100, Bangladesh","institution_ids":[]},{"raw_affiliation_string":"Population Health Studies Division, Center for Health Innovation, Research, Action, and Learning \u2013 Bangladesh (CHIRAL Bangladesh), 9-0 Chittaranjan Avenue, Dhaka-00, Bangladesh","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5013812916"],"corresponding_institution_ids":["https://openalex.org/I4210125938"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12413","display_name":"Health and Medical Education","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thalassemia","display_name":"thalassemia","score":1.0},{"id":"https://openalex.org/keywords/knowledge-and-attitudes","display_name":"knowledge and attitudes","score":0.8080000281333923},{"id":"https://openalex.org/keywords/college-students","display_name":"university students","score":0.972000002861023},{"id":"https://openalex.org/keywords/premarital-screening","display_name":"premarital screening","score":0.8970000147819519},{"id":"https://openalex.org/keywords/genetic-counseling","display_name":"genetic counseling","score":0.48899999260902405},{"id":"https://openalex.org/keywords/hemoglobinopathies","display_name":"hemoglobinopathies","score":0.5889999866485596},{"id":"https://openalex.org/keywords/bangladesh","display_name":"Bangladesh","score":0.3199999928474426}],"concepts":[{"id":"https://openalex.org/C2777799968","wikidata":"https://www.wikidata.org/wiki/Q185137","display_name":"Thalassemia","level":2,"score":0.6103162169456482},{"id":"https://openalex.org/C39896193","wikidata":"https://www.wikidata.org/wiki/Q380344","display_name":"Descriptive statistics","level":2,"score":0.5411578416824341},{"id":"https://openalex.org/C2781354955","wikidata":"https://www.wikidata.org/wiki/Q11920938","display_name":"Marital status","level":3,"score":0.48089078068733215},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4776971638202667},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42959272861480713},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.4233907461166382},{"id":"https://openalex.org/C509550671","wikidata":"https://www.wikidata.org/wiki/Q126945","display_name":"Medical education","level":1,"score":0.38677409291267395},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.34575843811035156},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.18537014722824097},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.1771768033504486},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.14625340700149536},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.12556025385856628},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.10193303227424622},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08957222104072571}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1101/2022.09.19.22280125","doi":"https://doi.org/10.1101/2022.09.19.22280125","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2022.09.19.22280125","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2022/09/20/2022.09.19.22280125.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1101/2022.09.19.22280125","doi":"https://doi.org/10.1101/2022.09.19.22280125","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2022.09.19.22280125","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2022/09/20/2022.09.19.22280125.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4296908217.pdf","grobid_xml":"https://content.openalex.org/works/W4296908217.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W2137755173","https://openalex.org/W2152345935","https://openalex.org/W2586419285","https://openalex.org/W2613605480","https://openalex.org/W2615246307","https://openalex.org/W2965585133","https://openalex.org/W3109881942","https://openalex.org/W4307003143"],"related_works":["https://openalex.org/W4317627200","https://openalex.org/W4307003143","https://openalex.org/W3143905807","https://openalex.org/W4390410380","https://openalex.org/W7151816309","https://openalex.org/W6958038364","https://openalex.org/W3119860964","https://openalex.org/W7220395146","https://openalex.org/W7118175645","https://openalex.org/W4386889197"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Thalassemia":[2],"is":[3,11,244,247],"the":[4,22,132,139,155,166,239,253,281],"most":[5],"common":[6],"congenital":[7],"single-gene":[8],"condition.":[9],"It":[10],"marked":[12],"by":[13,194,216],"a":[14,71,95,148,169,213,226],"lack":[15],"of":[16,20,48,84,97,127,138,151,154,165,172,218,241,272,283],"or":[17,24,204],"reduced":[18],"synthesis":[19],"either":[21],"alpha-":[23],"beta-globin":[25],"chains":[26],"and":[27,50,76,101,117,179,252,268,276],"passed":[28],"down":[29],"from":[30],"parents":[31],"to":[32,37,99,121,232],"offspring.":[33],"This":[34],"study":[35,143,219],"aimed":[36],"determine":[38],"how":[39,51],"healthy":[40],"students":[41,67,129,167,251],"in":[42,68,131,141,257],"Bangladeshi":[43],"public":[44,65,255],"universities":[45],"were":[46,107,119],"aware":[47],"thalassemia":[49,273],"they":[52],"felt":[53],"about":[54,160],"it.":[55],"Methods":[56],"A":[57,125],"cross-sectional":[58],"descriptive":[59],"online":[60,133],"survey":[61],"was":[62,144,212],"conducted":[63],"on":[64,94],"university":[66,250],"Bangladesh":[69],"using":[70,109],"structured":[72,81],"questionnaire":[73],"between":[74],"June":[75],"November":[77],"2020.":[78],"Students":[79],"completed":[80],"questionnaires":[82],"consisting":[83],"three":[85],"sections:":[86],"demographic":[87],"information,":[88],"ten":[89,102],"multiple-choice":[90],"knowledge":[91,188],"questions":[92],"rated":[93],"scale":[96],"0":[98],"10,":[100],"attitude":[103,228],"questions.":[104],"The":[105,135],"data":[106],"analyzed":[108],"Python.":[110],"Descriptive":[111],"statistics":[112],"methods":[113],"such":[114],"as":[115],"frequencies":[116],"percentages":[118],"used":[120],"present":[122],"data.":[123],"Results":[124],"total":[126],"681":[128],"participated":[130],"survey.":[134],"average":[136],"age":[137],"respondents":[140],"this":[142],"21.97":[145],"years,":[146],"with":[147,174],"standard":[149],"deviation":[150],"2.9.":[152],"Most":[153],"students,":[156],"611(89.72%),":[157],"had":[158,168],"heard":[159],"thalassemia.":[161,234],"Only":[162],"248":[163],"(36.42%)":[164],"fair":[170],"understanding":[171],"thalassemia,":[173],"138":[175],"(22.62%)":[176],"being":[177,182],"male":[178],"110":[180],"(18.03%)":[181],"female":[183],"(P-value":[184,196,201,207],"=":[185,197,202,208],"0.0819).":[186],"Students\u2019":[187],"level":[189],"did":[190],"not":[191],"differ":[192],"significantly":[193],"gender":[195],"0.0819),":[198],"marital":[199],"status":[200],"0.2281),":[203],"academic":[205],"year":[206],"0.4619),":[209],"but":[210],"there":[211],"substantial":[214],"variation":[215],"field":[217],"(0.0042).":[220],"However,":[221],"478":[222],"(78.36%)":[223],"participants":[224],"showed":[225],"positive":[227],"toward":[229],"\u201cPremarital":[230],"Screening\u201d":[231],"prevent":[233],"Conclusions":[235],"In":[236],"Bangladesh,":[237],"where":[238],"rate":[240],"family":[242],"marriage":[243],"high,":[245],"it":[246],"recommended":[248],"that":[249],"general":[254],"engage":[256],"long-term,":[258],"goal-oriented":[259],"prevention":[260],"measures.":[261],"These":[262],"initiatives":[263],"would":[264],"provide":[265],"crucial":[266],"information":[267],"increase":[269],"people\u2019s":[270],"awareness":[271],"when":[274],"married":[275],"after":[277],"becoming":[278],"parents,":[279],"reducing":[280],"impacts":[282],"illnesses.":[284]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2022-09-24T00:00:00"}