{"id":"https://openalex.org/W4296887696","doi":"https://doi.org/10.1016/j.arr.2022.101738","title":"The effects of aerobic exercise and transcranial direct current stimulation on cognitive function in older adults with and without cognitive impairment: A systematic review and meta-analysis","display_name":"The effects of aerobic exercise and transcranial direct current stimulation on cognitive function in older adults with and without cognitive impairment: A systematic review and meta-analysis","publication_year":2022,"publication_date":"2022-09-23","ids":{"openalex":"https://openalex.org/W4296887696","doi":"https://doi.org/10.1016/j.arr.2022.101738","pmid":"https://pubmed.ncbi.nlm.nih.gov/36162707"},"language":"en","primary_location":{"id":"doi:10.1016/j.arr.2022.101738","doi":"https://doi.org/10.1016/j.arr.2022.101738","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.arr.2022.101738","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1568163722001805/pdf","source":{"id":"https://openalex.org/S117312820","display_name":"Ageing Research Reviews","issn_l":"1568-1637","issn":["1568-1637","1872-9649"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ageing Research Reviews","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S1568163722001805/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027223981","display_name":"Karolina Talar","orcid":"https://orcid.org/0000-0001-5945-2130","observed_orcids":["https://orcid.org/0000-0001-5945-2130"]},"institutions":[{"id":"https://openalex.org/I227774917","display_name":"University of Physical Culture in Krak\u00f3w","ror":"https://ror.org/05vy8np18","country_code":"PL","type":"education","lineage":["https://openalex.org/I227774917"]},{"id":"https://openalex.org/I4210094118","display_name":"Universit\u00e4tsklinikum T\u00fcbingen","ror":"https://ror.org/00pjgxh97","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094118"]},{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE","PL"],"is_corresponding":true,"raw_author_name":"K. Talar","raw_affiliation_strings":["Faculty of Motor Rehabilitation, University of Physical Education, Krakow, Poland; Institute for Neuromodulation and Neurotechnology, Department of Neurosurgery and Neurotechnology, University Hospital and University of T\u00fcbingen, Germany. Electronic address: karolina.talar@uni-tuebingen.de","Faculty of Motor Rehabilitation, University of Physical Education, Krakow, Poland","Institute for Neuromodulation and Neurotechnology, Department of Neurosurgery and Neurotechnology, University Hospital and University of T\u00fcbingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Motor Rehabilitation, University of Physical Education, Krakow, Poland; Institute for Neuromodulation and Neurotechnology, Department of Neurosurgery and Neurotechnology, University Hospital and University of T\u00fcbingen, Germany. Electronic address: karolina.talar@uni-tuebingen.de","institution_ids":["https://openalex.org/I227774917","https://openalex.org/I8087733"]},{"raw_affiliation_string":"Faculty of Motor Rehabilitation, University of Physical Education, Krakow, Poland","institution_ids":["https://openalex.org/I227774917"]},{"raw_affiliation_string":"Institute for Neuromodulation and Neurotechnology, Department of Neurosurgery and Neurotechnology, University Hospital and University of T\u00fcbingen, Germany","institution_ids":["https://openalex.org/I4210094118","https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073133890","display_name":"Tom\u00e1\u0161 V\u011btrovsk\u00fd","orcid":"https://orcid.org/0000-0003-2529-7069","observed_orcids":["https://orcid.org/0000-0003-2529-7069"]},"institutions":[{"id":"https://openalex.org/I21250087","display_name":"Charles University","ror":"https://ror.org/024d6js02","country_code":"CZ","type":"education","lineage":["https://openalex.org/I21250087"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"T. Vetrovsky","raw_affiliation_strings":["Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic","institution_ids":["https://openalex.org/I21250087"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050615075","display_name":"M. van Haren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"M. van Haren","raw_affiliation_strings":["Department of Human Movement Sciences, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Movement Sciences, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001041664","display_name":"J\u00e1nos N\u00e9gyesi","orcid":"https://orcid.org/0000-0001-5055-3242","observed_orcids":["https://orcid.org/0000-0001-5055-3242"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"J. N\u00e9gyesi","raw_affiliation_strings":["Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083984924","display_name":"Urs Granacher","orcid":"https://orcid.org/0000-0002-7095-813X","observed_orcids":["https://orcid.org/0000-0002-7095-813X"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"U. Granacher","raw_affiliation_strings":["Department of Sport and Sport Science, Exercise and Human Movement Science, University of Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sport and Sport Science, Exercise and Human Movement Science, University of Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024281883","display_name":"M\u00e1rk V\u00e1czi","orcid":"https://orcid.org/0000-0002-7047-7088","observed_orcids":["https://orcid.org/0000-0002-7047-7088"]},"institutions":[{"id":"https://openalex.org/I79741316","display_name":"University of Pecs","ror":"https://ror.org/037b5pv06","country_code":"HU","type":"education","lineage":["https://openalex.org/I79741316"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"M. V\u00e1czi","raw_affiliation_strings":["Institute of Sport Sciences and Physical Education, University of P\u00e9cs, P\u00e9cs, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Sport Sciences and Physical Education, University of P\u00e9cs, P\u00e9cs, Hungary","institution_ids":["https://openalex.org/I79741316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032987201","display_name":"Elisa Mart\u00edn\u2010Ar\u00e9valo","orcid":"https://orcid.org/0000-0002-4546-6440","observed_orcids":["https://orcid.org/0000-0002-4546-6440"]},"institutions":[{"id":"https://openalex.org/I173304897","display_name":"Universidad de Granada","ror":"https://ror.org/04njjy449","country_code":"ES","type":"education","lineage":["https://openalex.org/I173304897"]},{"id":"https://openalex.org/I4405276228","display_name":"Centro de Investigaci\u00f3n Mente, Cerebro y Comportamiento","ror":"https://ror.org/051r21g65","country_code":"ES","type":"facility","lineage":["https://openalex.org/I173304897","https://openalex.org/I4405276228"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"E. Mart\u00edn-Ar\u00e9valo","raw_affiliation_strings":["Department of Experimental Psychology, and Mind, Brain, and Behavior Research Center (CIMCYC), University of Granada, Granada, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Psychology, and Mind, Brain, and Behavior Research Center (CIMCYC), University of Granada, Granada, Spain","institution_ids":["https://openalex.org/I173304897","https://openalex.org/I4405276228"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M.F. Del Olmo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I182083151","display_name":"Universidad Rey Juan Carlos","ror":"https://ror.org/01v5cv687","country_code":"ES","type":"education","lineage":["https://openalex.org/I182083151"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M.F. Del Olmo","raw_affiliation_strings":["Area of Sport Sciences, Faculty of Sports Sciences and Physical Education, Center for Sport Studies, King Juan Carlos University, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Area of Sport Sciences, Faculty of Sports Sciences and Physical Education, Center for Sport Studies, King Juan Carlos University, Madrid, Spain","institution_ids":["https://openalex.org/I182083151"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078244785","display_name":"Ewa Ka\u0142amacka","orcid":"https://orcid.org/0000-0002-7813-2930","observed_orcids":["https://orcid.org/0000-0002-7813-2930"]},"institutions":[{"id":"https://openalex.org/I227774917","display_name":"University of Physical Culture in Krak\u00f3w","ror":"https://ror.org/05vy8np18","country_code":"PL","type":"education","lineage":["https://openalex.org/I227774917"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"E. Ka\u0142amacka","raw_affiliation_strings":["Faculty of Motor Rehabilitation, University of Physical Education, Krakow, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Motor Rehabilitation, University of Physical Education, Krakow, Poland","institution_ids":["https://openalex.org/I227774917"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063397302","display_name":"Tibor Hortob\u00e1gyi","orcid":"https://orcid.org/0000-0002-5731-6423","observed_orcids":["https://orcid.org/0000-0002-5731-6423"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]},{"id":"https://openalex.org/I4210099897","display_name":"Somogy Megyei Kaposi M\u00f3r Oktat\u00f3 K\u00f3rh\u00e1z","ror":"https://ror.org/015mptv94","country_code":"HU","type":"healthcare","lineage":["https://openalex.org/I4210099897"]},{"id":"https://openalex.org/I4210112186","display_name":"Hungarian University of Sports Science","ror":"https://ror.org/01zh80k81","country_code":"HU","type":"education","lineage":["https://openalex.org/I4210112186"]},{"id":"https://openalex.org/I79741316","display_name":"University of Pecs","ror":"https://ror.org/037b5pv06","country_code":"HU","type":"education","lineage":["https://openalex.org/I79741316"]}],"countries":["HU","NL"],"is_corresponding":false,"raw_author_name":"T. Hortob\u00e1gyi","raw_affiliation_strings":["Department of Human Movement Sciences, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Institute of Sport Sciences and Physical Education, University of P\u00e9cs, P\u00e9cs, Hungary; Department of Kinesiology, Hungarian University of Sport Science, Budapest, Hungary; Somogy County Kaposi M\u00f3r Teaching Hospital, Kaposv\u00e1r, Hungary","Department of Human Movement Sciences, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands","Department of Kinesiology, Hungarian University of Sport Science, Budapest, Hungary","Institute of Sport Sciences and Physical Education, University of P\u00e9cs, P\u00e9cs, Hungary","Somogy County Kaposi M\u00f3r Teaching Hospital, Kaposv\u00e1r, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Movement Sciences, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Institute of Sport Sciences and Physical Education, University of P\u00e9cs, P\u00e9cs, Hungary; Department of Kinesiology, Hungarian University of Sport Science, Budapest, Hungary; Somogy County Kaposi M\u00f3r Teaching Hospital, Kaposv\u00e1r, Hungary","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384","https://openalex.org/I4210112186","https://openalex.org/I79741316"]},{"raw_affiliation_string":"Department of Human Movement Sciences, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]},{"raw_affiliation_string":"Department of Kinesiology, Hungarian University of Sport Science, Budapest, Hungary","institution_ids":["https://openalex.org/I4210112186"]},{"raw_affiliation_string":"Institute of Sport Sciences and Physical Education, University of P\u00e9cs, P\u00e9cs, Hungary","institution_ids":["https://openalex.org/I79741316"]},{"raw_affiliation_string":"Somogy County Kaposi M\u00f3r Teaching Hospital, Kaposv\u00e1r, Hungary","institution_ids":["https://openalex.org/I4210099897"]}]}],"institutions":[],"countries_distinct_count":7,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5027223981"],"corresponding_institution_ids":["https://openalex.org/I227774917","https://openalex.org/I4210094118","https://openalex.org/I8087733"],"apc_list":{"value":4820,"currency":"USD","value_usd":4820},"apc_paid":{"value":4820,"currency":"USD","value_usd":4820},"fwci":1.6087,"has_fulltext":true,"cited_by_count":58,"citation_normalized_percentile":{"value":0.84895833,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"81","issue":null,"first_page":"101738","last_page":"101738"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10614","display_name":"Transcranial Magnetic Stimulation Studies","score":0.8794000148773193,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10614","display_name":"Transcranial Magnetic Stimulation Studies","score":0.8794000148773193,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.10459999740123749,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10352","display_name":"Physical Activity and Health","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aerobic-exercise","display_name":"aerobic exercise","score":0.9929999709129333},{"id":"https://openalex.org/keywords/transcranial-direct-current-stimulation","display_name":"transcranial direct current stimulation","score":1.0},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.6510000228881836},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.8659999966621399},{"id":"https://openalex.org/keywords/mild-cognitive-impairment","display_name":"mild cognitive impairment","score":0.9909999966621399},{"id":"https://openalex.org/keywords/dementia","display_name":"dementia","score":1.0},{"id":"https://openalex.org/keywords/global-cognition","display_name":"global cognition","score":0.6460000276565552},{"id":"https://openalex.org/keywords/working-memory","display_name":"working memory","score":0.9890000224113464},{"id":"https://openalex.org/keywords/executive-function","display_name":"executive function","score":0.9990000128746033},{"id":"https://openalex.org/keywords/age-related-cognitive-decline","display_name":"age-related cognitive decline","score":0.7799999713897705},{"id":"https://openalex.org/keywords/non-invasive-brain-stimulation","display_name":"non-invasive brain stimulation","score":0.753000020980835},{"id":"https://openalex.org/keywords/cognitive-training","display_name":"cognitive training","score":0.6269999742507935},{"id":"https://openalex.org/keywords/synergistic-effect","display_name":"synergistic effect","score":0.5130000114440918},{"id":"https://openalex.org/keywords/cognitive-rehabilitation","display_name":"cognitive rehabilitation","score":0.30300000309944153},{"id":"https://openalex.org/keywords/neuroplasticity","display_name":"neuroplasticity","score":0.5379999876022339},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.4269999861717224},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.7749999761581421},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.5379999876022339},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.32199999690055847}],"concepts":[{"id":"https://openalex.org/C2777803708","wikidata":"https://www.wikidata.org/wiki/Q603398","display_name":"Transcranial direct-current stimulation","level":3,"score":0.83609938621521},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.7874826192855835},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.704580545425415},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5885508060455322},{"id":"https://openalex.org/C2779602242","wikidata":"https://www.wikidata.org/wiki/Q1498506","display_name":"Cognitive training","level":3,"score":0.5339533090591431},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.5257081389427185},{"id":"https://openalex.org/C2776632958","wikidata":"https://www.wikidata.org/wiki/Q6906262","display_name":"Montreal Cognitive Assessment","level":4,"score":0.5178161263465881},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.46666449308395386},{"id":"https://openalex.org/C2775968953","wikidata":"https://www.wikidata.org/wiki/Q783092","display_name":"Executive functions","level":3,"score":0.4561215937137604},{"id":"https://openalex.org/C2985799443","wikidata":"https://www.wikidata.org/wiki/Q4955838","display_name":"Brain stimulation","level":3,"score":0.45518726110458374},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.4486631155014038},{"id":"https://openalex.org/C185711340","wikidata":"https://www.wikidata.org/wiki/Q5347381","display_name":"Effects of sleep deprivation on cognitive performance","level":3,"score":0.44522470235824585},{"id":"https://openalex.org/C21963081","wikidata":"https://www.wikidata.org/wiki/Q11337567","display_name":"Working memory","level":3,"score":0.42701026797294617},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2916589379310608},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29072731733322144},{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.25092893838882446},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.14687860012054443},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.08233964443206787},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0687071681022644}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003704","descriptor_name":"Dementia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003704","descriptor_name":"Dementia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003704","descriptor_name":"Dementia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003704","descriptor_name":"Dementia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D065908","descriptor_name":"Transcranial Direct Current Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D065908","descriptor_name":"Transcranial Direct Current Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D065908","descriptor_name":"Transcranial Direct Current Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D065908","descriptor_name":"Transcranial Direct Current Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.arr.2022.101738","doi":"https://doi.org/10.1016/j.arr.2022.101738","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.arr.2022.101738","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1568163722001805/pdf","source":{"id":"https://openalex.org/S117312820","display_name":"Ageing Research Reviews","issn_l":"1568-1637","issn":["1568-1637","1872-9649"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ageing Research Reviews","raw_type":"journal-article"},{"id":"pmid:36162707","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36162707","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ageing research reviews","raw_type":"Journal Article"},{"id":"pmh:oai:digibug.ugr.es:10481/77642","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10481/77642","pdf_url":null,"source":{"id":"https://openalex.org/S4306400567","display_name":"Institutional Repository of the University of Granada (University of Granada)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I173304897","host_organization_name":"Universidad de Granada","host_organization_lineage":["https://openalex.org/I173304897"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.rug.nl:openaire/616abbe6-ee35-4ef2-bfc2-fb387d75fff2","doi":null,"is_oa":true,"landing_page_url":"https://research.rug.nl/files/247460292/1_s2.0_S1568163722001805_main.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Talar, K, Vetrovsky, T, van Haren, M, N\u00e9gyesi, J, Granacher, U, V\u00e1czi, M, Mart\u00edn-Ar\u00e9valo, E, Del Olmo, M F, Ka\u0142amacka, E & Hortob\u00e1gyi, T 2022, 'The effects of aerobic exercise and transcranial direct current stimulation on cognitive function in older adults with and without cognitive impairment : A systematic review and meta-analysis', Ageing Research Reviews, vol. 81, 101738. https://doi.org/10.1016/j.arr.2022.101738","raw_type":"info:eu-repo/semantics/review"},{"id":"pmh:rug:oai:pure.rug.nl:publications/616abbe6-ee35-4ef2-bfc2-fb387d75fff2","doi":null,"is_oa":true,"landing_page_url":"https://research.rug.nl/en/publications/616abbe6-ee35-4ef2-bfc2-fb387d75fff2","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Ageing Research Reviews, 81:101738. ELSEVIER IRELAND LTD","raw_type":"info:eu-repo/semantics/other"}],"best_oa_location":{"id":"doi:10.1016/j.arr.2022.101738","doi":"https://doi.org/10.1016/j.arr.2022.101738","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.arr.2022.101738","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1568163722001805/pdf","source":{"id":"https://openalex.org/S117312820","display_name":"Ageing Research Reviews","issn_l":"1568-1637","issn":["1568-1637","1872-9649"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ageing Research Reviews","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320309755","display_name":"Univerzita Karlova v Praze","ror":"https://ror.org/024d6js02"},{"id":"https://openalex.org/F4320325904","display_name":"P\u00e9csi Tudom\u00e1nyegyetem","ror":"https://ror.org/037b5pv06"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4296887696.pdf","grobid_xml":"https://content.openalex.org/works/W4296887696.grobid-xml"},"referenced_works_count":231,"referenced_works":["https://openalex.org/W111317458","https://openalex.org/W136768607","https://openalex.org/W610095188","https://openalex.org/W1536479623","https://openalex.org/W1546116882","https://openalex.org/W1614035160","https://openalex.org/W1727379187","https://openalex.org/W1884715243","https://openalex.org/W1910549955","https://openalex.org/W1963553614","https://openalex.org/W1963811662","https://openalex.org/W1968580928","https://openalex.org/W1973526337","https://openalex.org/W1977466344","https://openalex.org/W1979325947","https://openalex.org/W1981188819","https://openalex.org/W1990749080","https://openalex.org/W2000822413","https://openalex.org/W2003418939","https://openalex.org/W2005355670","https://openalex.org/W2007948103","https://openalex.org/W2009292210","https://openalex.org/W2010860427","https://openalex.org/W2014877105","https://openalex.org/W2015247655","https://openalex.org/W2017192319","https://openalex.org/W2034488360","https://openalex.org/W2035028229","https://openalex.org/W2039688993","https://openalex.org/W2045296013","https://openalex.org/W2047262956","https://openalex.org/W2055362996","https://openalex.org/W2055649795","https://openalex.org/W2057070604","https://openalex.org/W2058264807","https://openalex.org/W2067071866","https://openalex.org/W2068800228","https://openalex.org/W2070310146","https://openalex.org/W2071762564","https://openalex.org/W2072963015","https://openalex.org/W2074127930","https://openalex.org/W2077711513","https://openalex.org/W2079890482","https://openalex.org/W2085043903","https://openalex.org/W2087813588","https://openalex.org/W2092674727","https://openalex.org/W2096248731","https://openalex.org/W2096688252","https://openalex.org/W2097273459","https://openalex.org/W2099899980","https://openalex.org/W2102968146","https://openalex.org/W2107501599","https://openalex.org/W2110367802","https://openalex.org/W2113982001","https://openalex.org/W2114849332","https://openalex.org/W2115040753","https://openalex.org/W2115625328","https://openalex.org/W2116428877","https://openalex.org/W2117641008","https://openalex.org/W2119268626","https://openalex.org/W2123845631","https://openalex.org/W2125657871","https://openalex.org/W2127818482","https://openalex.org/W2128127086","https://openalex.org/W2128409798","https://openalex.org/W2129980646","https://openalex.org/W2133114348","https://openalex.org/W2133911471","https://openalex.org/W2135810292","https://openalex.org/W2138234128","https://openalex.org/W2141061973","https://openalex.org/W2143997631","https://openalex.org/W2144051538","https://openalex.org/W2148716787","https://openalex.org/W2149113801","https://openalex.org/W2149983193","https://openalex.org/W2150849842","https://openalex.org/W2154074499","https://openalex.org/W2154159504","https://openalex.org/W2156681310","https://openalex.org/W2163600133","https://openalex.org/W2165922581","https://openalex.org/W2166949480","https://openalex.org/W2178625776","https://openalex.org/W2217398503","https://openalex.org/W2265969495","https://openalex.org/W2280991203","https://openalex.org/W2283864761","https://openalex.org/W2286113349","https://openalex.org/W2315929518","https://openalex.org/W2317922289","https://openalex.org/W2339661176","https://openalex.org/W2339940577","https://openalex.org/W2368066211","https://openalex.org/W2419371116","https://openalex.org/W2419644991","https://openalex.org/W2426876147","https://openalex.org/W2429502974","https://openalex.org/W2465651823","https://openalex.org/W2467410650","https://openalex.org/W2467453756","https://openalex.org/W2482468748","https://openalex.org/W2518187356","https://openalex.org/W2519565472","https://openalex.org/W2520082135","https://openalex.org/W2529310142","https://openalex.org/W2532210012","https://openalex.org/W2551013628","https://openalex.org/W2551842538","https://openalex.org/W2578753593","https://openalex.org/W2586548781","https://openalex.org/W2606017535","https://openalex.org/W2607215421","https://openalex.org/W2608193295","https://openalex.org/W2611227403","https://openalex.org/W2616004589","https://openalex.org/W2620562051","https://openalex.org/W2745375780","https://openalex.org/W2747000752","https://openalex.org/W2753461022","https://openalex.org/W2754070404","https://openalex.org/W2757881549","https://openalex.org/W2760038953","https://openalex.org/W2766233271","https://openalex.org/W2771594778","https://openalex.org/W2784013409","https://openalex.org/W2785876227","https://openalex.org/W2787983500","https://openalex.org/W2801573807","https://openalex.org/W2803160270","https://openalex.org/W2808541049","https://openalex.org/W2809104382","https://openalex.org/W2810234006","https://openalex.org/W2810371602","https://openalex.org/W2888288537","https://openalex.org/W2890130377","https://openalex.org/W2893047117","https://openalex.org/W2898401647","https://openalex.org/W2903356514","https://openalex.org/W2903772775","https://openalex.org/W2905294679","https://openalex.org/W2907895038","https://openalex.org/W2908556655","https://openalex.org/W2909610103","https://openalex.org/W2912676447","https://openalex.org/W2915023902","https://openalex.org/W2917196673","https://openalex.org/W2918514057","https://openalex.org/W2923162815","https://openalex.org/W2927777239","https://openalex.org/W2933586395","https://openalex.org/W2934350162","https://openalex.org/W2941236380","https://openalex.org/W2944012487","https://openalex.org/W2944071401","https://openalex.org/W2945523093","https://openalex.org/W2950048198","https://openalex.org/W2955151020","https://openalex.org/W2955786710","https://openalex.org/W2958717882","https://openalex.org/W2959443811","https://openalex.org/W2963806677","https://openalex.org/W2973351917","https://openalex.org/W2982627628","https://openalex.org/W2991049508","https://openalex.org/W2992750141","https://openalex.org/W2995042276","https://openalex.org/W2995990008","https://openalex.org/W2996309028","https://openalex.org/W2998189584","https://openalex.org/W2999148048","https://openalex.org/W3000512444","https://openalex.org/W3000620631","https://openalex.org/W3007983647","https://openalex.org/W3009219707","https://openalex.org/W3010705665","https://openalex.org/W3012773541","https://openalex.org/W3012896574","https://openalex.org/W3016719937","https://openalex.org/W3017338992","https://openalex.org/W3019744878","https://openalex.org/W3024205036","https://openalex.org/W3024408794","https://openalex.org/W3027731438","https://openalex.org/W3034761510","https://openalex.org/W3035449539","https://openalex.org/W3037073394","https://openalex.org/W3038863628","https://openalex.org/W3040243326","https://openalex.org/W3041679845","https://openalex.org/W3042406196","https://openalex.org/W3045879016","https://openalex.org/W3070191335","https://openalex.org/W3091653260","https://openalex.org/W3092684083","https://openalex.org/W3093585643","https://openalex.org/W3097964601","https://openalex.org/W3108507079","https://openalex.org/W3110133582","https://openalex.org/W3118601194","https://openalex.org/W3118615836","https://openalex.org/W3125322711","https://openalex.org/W3127411414","https://openalex.org/W3127520585","https://openalex.org/W3130994319","https://openalex.org/W3132860003","https://openalex.org/W3136980102","https://openalex.org/W3142417005","https://openalex.org/W3143866006","https://openalex.org/W3147475940","https://openalex.org/W3153539755","https://openalex.org/W3153642330","https://openalex.org/W3153959819","https://openalex.org/W3158867864","https://openalex.org/W3164195187","https://openalex.org/W3171666325","https://openalex.org/W3174104939","https://openalex.org/W3174678736","https://openalex.org/W3175460829","https://openalex.org/W3175936564","https://openalex.org/W3175947353","https://openalex.org/W3177981858","https://openalex.org/W3180161429","https://openalex.org/W3181129875","https://openalex.org/W3183910177","https://openalex.org/W3187842018","https://openalex.org/W3190464732","https://openalex.org/W3193651338","https://openalex.org/W3208615649","https://openalex.org/W4200594556","https://openalex.org/W4234085405"],"related_works":["https://openalex.org/W3094606447","https://openalex.org/W4386092312","https://openalex.org/W2911887425","https://openalex.org/W2592166659","https://openalex.org/W2608007647","https://openalex.org/W2616004589","https://openalex.org/W2096118154","https://openalex.org/W1605889908","https://openalex.org/W3207952290","https://openalex.org/W4311710260"],"abstract_inverted_index":{"BACKGROUND:":[0],"Aerobic":[1],"exercise":[2],"(AE)":[3],"may":[4,438],"slow":[5,443],"age-related":[6],"cognitive":[7,17,55,83,94,107,181,190,379,402,447,475],"decline.":[8],"However,":[9],"such":[10,88],"cognition-sparing":[11],"effects":[12,71,76,90,132,169],"are":[13],"not":[14],"uniform":[15],"across":[16],"domains":[18],"and":[19,33,66,72,81,104,135,144,155,175,177,187,204,220,298,337,383,400,429,451],"studies.":[20],"Transcranial":[21],"direct":[22],"current":[23],"stimulation":[24,32],"(tDCS)":[25],"is":[26,34,50,96],"a":[27,38,159,196,464],"form":[28],"of":[29,48,115,133,170,206,267,315,432,446,459,474],"non-invasive":[30],"brain":[31],"also":[35,51],"emerging":[36],"as":[37],"potential":[39,441],"alternative":[40],"to":[41,122,210,442],"pharmaceutical":[42],"therapies.":[43],"Like":[44],"AE,":[45,433],"the":[46,168,253,264,268,273,286,427,440,457],"effectiveness":[47],"tDCS":[49,67,99,128,136,173,178,299,365,437],"inconsistent":[52],"for":[53],"reducing":[54],"impairment":[56,108,191],"in":[57,77,100,148,183,244,248,285,311,351,386,404,449],"ageing.":[58],"The":[59,113],"unexplored":[60],"possibility":[61],"exists":[62],"that":[63,166,425,463],"pairing":[64,125,434],"AE":[65,126,134,171,176,288,325,348,435],"could":[68,129],"produce":[69],"synergistic":[70,89],"reciprocally":[73],"augment":[74,130],"cognition-improving":[75],"older":[78,101,149,184,316,352,387,405],"individuals":[79,102,150,185],"with":[80,98,103,119,127,151,186,257,354,389,421,436,471],"without":[82,105,153,188],"impairments.":[84],"Previous":[85],"research":[86],"found":[87],"on":[91,137,180,215],"cognition":[92,139,470],"when":[93],"training":[95],"paired":[97],"mild":[106,189],"(MCI)":[109,192],"or":[110,152,193],"dementia.":[111,156,194,452],"AIM:":[112],"purpose":[114],"this":[116,460],"systematic":[117,161,419],"review":[118,420,462],"meta-analysis":[120,422],"was":[121],"explore":[123],"if":[124,246],"singular":[131],"global":[138],"(GC),":[140],"working":[141],"memory":[142],"(WM)":[143],"executive":[145],"function":[146,182,380,403],"(EF)":[147],"MCI":[154,355,450],"METHODS:":[157],"Using":[158,195],"PRISMA-based":[160],"review,":[162],"we":[163,199,213],"compiled":[164],"studies":[165,270,282,454],"examined":[167],"alone,":[172,174],"combined":[179,318,385],"PICOS":[197],"approach,":[198],"systematically":[200],"searched":[201],"PubMed,":[202],"Scopus":[203],"Web":[205],"Science":[207],"searches":[208],"up":[209],"December":[211],"2021,":[212],"focused":[214],"'MoCA',":[216],"'MMSE',":[217],"'Mini-Cog'":[218],"(measures)":[219],"'cognition',":[221],"'cognitive":[222,225],"function',":[223,228],"'cognitive',":[224],"performance',":[226],"'executive":[227,229],"process',":[230],"'attention',":[231],"'memory',":[232],"'memory":[233],"performance'":[234],"(outcome":[235],"terms).":[236],"We":[237,262],"included":[238,269,284],"only":[239],"randomized":[240],"controlled":[241],"trials":[242],"(RTC)":[243,271],"humans":[245],"available":[247],"English":[249],"full":[250],"text":[251],"over":[252,260],"past":[254],"20":[255],"years,":[256],"participants'":[258],"age":[259],"60.":[261],"assessed":[263],"methodological":[265],"quality":[266],"by":[272],"Physiotherapy":[274],"Evidence":[275],"Database":[276],"(PEDro)":[277],"scale.":[278],"RESULTS:":[279],"Overall,":[280],"68":[281],"were":[283],"meta-analyses.":[287],"(ES":[289,300,328,339,356,368,391,408],"=":[290,296,301,307,329,335,340,346,357,363,369,375,392,398,409,415],"0.56":[291],"[95%":[292,303,331,342,359,394,411],"CI:":[293,304,332,343,360,372,395,412],"0.28-0.83],":[294],"p":[295,306,334,345,362,374,397,414],"0.01)":[297,336],"0.69":[302,370,410],"0.12-1.26],":[305,373],"0.02)":[308],"improved":[309,326,349,366,401],"GC":[310,327,350,367],"all":[312,377],"three":[313,378],"groups":[314],"adults":[317,353,388,406],"(healthy,":[319],"MCI,":[320],"demented).":[321],"In":[322],"healthy":[323],"population,":[324],"0.46":[330],"0.22-0.69],":[333],"EF":[338],"0.27":[341],"0.05-0.49],":[344],"0.02).":[347],"0.76":[358],"0.21-1.32],":[361],"0.01).":[364,416],"[90%":[371],"0.02),":[376],"(GC,":[381],"WM":[382],"EF)":[384],"dementia":[390],"1.12":[393],"0.04-2.19],":[396],"0.04)":[399],"overall":[407],"0.20-1,18],":[413],"CONCLUSION:":[417],"Our":[418],"provided":[423],"evidence":[424],"beyond":[426],"cardiovascular":[428],"fitness":[430],"benefits":[431],"have":[439],"symptom":[444],"progression":[445],"decline":[448],"Future":[453],"will":[455],"examine":[456],"hypothesis":[458],"present":[461],"potentiating":[465],"effect":[466],"would":[467],"incrementally":[468],"improve":[469],"increasing":[472],"severity":[473],"impairment.":[476]},"counts_by_year":[{"year":2026,"cited_by_count":18},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":9}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}