{"id":"https://openalex.org/W4296794633","doi":"https://doi.org/10.1017/s0954579422000931","title":"Gene\u2013environment interaction using polygenic scores: Do polygenic scores for psychopathology moderate predictions from environmental risk to behavior problems?","display_name":"Gene\u2013environment interaction using polygenic scores: Do polygenic scores for psychopathology moderate predictions from environmental risk to behavior problems?","publication_year":2022,"publication_date":"2022-09-23","ids":{"openalex":"https://openalex.org/W4296794633","doi":"https://doi.org/10.1017/s0954579422000931","pmid":"https://pubmed.ncbi.nlm.nih.gov/36148872","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7613991"},"language":"en","primary_location":{"id":"doi:10.1017/s0954579422000931","doi":"https://doi.org/10.1017/s0954579422000931","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0954579422000931","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/20A7246CEF99EFD0B8EA104983EA127C/S0954579422000931a.pdf/div-class-title-gene-environment-interaction-using-polygenic-scores-do-polygenic-scores-for-psychopathology-moderate-predictions-from-environmental-risk-to-behavior-problems-div.pdf","source":{"id":"https://openalex.org/S6115874","display_name":"Development and Psychopathology","issn_l":"0954-5794","issn":["0954-5794","1469-2198"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development and Psychopathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/20A7246CEF99EFD0B8EA104983EA127C/S0954579422000931a.pdf/div-class-title-gene-environment-interaction-using-polygenic-scores-do-polygenic-scores-for-psychopathology-moderate-predictions-from-environmental-risk-to-behavior-problems-div.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007723142","display_name":"Robert J. Plomin","orcid":"https://orcid.org/0000-0002-0756-3629","observed_orcids":["https://orcid.org/0000-0002-0756-3629"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Robert Plomin","raw_affiliation_strings":["Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK"],"raw_orcid":"https://orcid.org/0000-0002-0756-3629","affiliations":[{"raw_affiliation_string":"Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053018192","display_name":"Agnieszka Gidziela","orcid":"https://orcid.org/0000-0002-3400-4638","observed_orcids":["https://orcid.org/0000-0002-3400-4638"]},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Agnieszka Gidziela","raw_affiliation_strings":["School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK","School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK","institution_ids":["https://openalex.org/I166337079"]},{"raw_affiliation_string":"School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK and","institution_ids":["https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026023368","display_name":"Margherita Malanchini","orcid":"https://orcid.org/0000-0002-7257-6119","observed_orcids":["https://orcid.org/0000-0002-7257-6119"]},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Margherita Malanchini","raw_affiliation_strings":["School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK","School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK","institution_ids":["https://openalex.org/I166337079"]},{"raw_affiliation_string":"School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK and","institution_ids":["https://openalex.org/I166337079"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039018032","display_name":"Sophie von Stumm","orcid":"https://orcid.org/0000-0002-0447-5471","observed_orcids":["https://orcid.org/0000-0002-0447-5471"]},"institutions":[{"id":"https://openalex.org/I52099693","display_name":"University of York","ror":"https://ror.org/04m01e293","country_code":"GB","type":"education","lineage":["https://openalex.org/I52099693"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sophie von Stumm","raw_affiliation_strings":["Department of Education, University of York, York, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Education, University of York, York, UK","institution_ids":["https://openalex.org/I52099693"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5007723142"],"corresponding_institution_ids":["https://openalex.org/I183935753"],"apc_list":{"value":3255,"currency":"USD","value_usd":3255},"apc_paid":{"value":3255,"currency":"USD","value_usd":3255},"fwci":3.4545,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.94000346,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"34","issue":"5","first_page":"1816","last_page":"1826"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.4844000041484833,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.4844000041484833,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10182","display_name":"Child and Adolescent Psychosocial and Emotional Development","score":0.2791000008583069,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.09860000014305115,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-environment-interaction","display_name":"gene-environment interaction","score":0.9980000257492065},{"id":"https://openalex.org/keywords/polygenic-risk-score","display_name":"polygenic risk score","score":0.9990000128746033},{"id":"https://openalex.org/keywords/attention-deficit-hyperactivity-disorder","display_name":"attention deficit hyperactivity disorder","score":0.9710000157356262},{"id":"https://openalex.org/keywords/neuroticism","display_name":"neuroticism","score":0.9879999756813049},{"id":"https://openalex.org/keywords/environmental-risk","display_name":"environmental risk","score":0.8410000205039978},{"id":"https://openalex.org/keywords/child-behavior-problems","display_name":"child behavior problems","score":0.7850000262260437},{"id":"https://openalex.org/keywords/hyperactivity-inattention","display_name":"hyperactivity/inattention","score":0.8809999823570251},{"id":"https://openalex.org/keywords/conduct-problems","display_name":"conduct problems","score":1.0},{"id":"https://openalex.org/keywords/emotional-symptoms","display_name":"emotional symptoms","score":0.9620000123977661},{"id":"https://openalex.org/keywords/peer-relationship-problems","display_name":"peer relationship problems","score":0.9829999804496765},{"id":"https://openalex.org/keywords/externalizing-problems","display_name":"externalizing problems","score":0.7039999961853027},{"id":"https://openalex.org/keywords/early-childhood","display_name":"early childhood","score":0.4309999942779541},{"id":"https://openalex.org/keywords/heritability-of-behavior","display_name":"heritability of behavior","score":0.546999990940094}],"concepts":[{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.7247470021247864},{"id":"https://openalex.org/C94612546","wikidata":"https://www.wikidata.org/wiki/Q1540168","display_name":"Neuroticism","level":3,"score":0.7068856954574585},{"id":"https://openalex.org/C123273963","wikidata":"https://www.wikidata.org/wiki/Q624758","display_name":"Psychopathology","level":2,"score":0.5279202461242676},{"id":"https://openalex.org/C2780783007","wikidata":"https://www.wikidata.org/wiki/Q181923","display_name":"Attention deficit hyperactivity disorder","level":2,"score":0.4654237926006317},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.4635540544986725},{"id":"https://openalex.org/C53500534","wikidata":"https://www.wikidata.org/wiki/Q1204375","display_name":"Behavioural genetics","level":2,"score":0.4401613771915436},{"id":"https://openalex.org/C2993137441","wikidata":"https://www.wikidata.org/wiki/Q28135712","display_name":"Polygenic risk score","level":5,"score":0.43316149711608887},{"id":"https://openalex.org/C2780135496","wikidata":"https://www.wikidata.org/wiki/Q596474","display_name":"Conduct disorder","level":2,"score":0.4311678111553192},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.35581403970718384},{"id":"https://openalex.org/C187288502","wikidata":"https://www.wikidata.org/wiki/Q641118","display_name":"Personality","level":2,"score":0.2035168707370758},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1191626787185669},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10778650641441345},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.08518058061599731},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.0},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1017/s0954579422000931","doi":"https://doi.org/10.1017/s0954579422000931","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0954579422000931","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/20A7246CEF99EFD0B8EA104983EA127C/S0954579422000931a.pdf/div-class-title-gene-environment-interaction-using-polygenic-scores-do-polygenic-scores-for-psychopathology-moderate-predictions-from-environmental-risk-to-behavior-problems-div.pdf","source":{"id":"https://openalex.org/S6115874","display_name":"Development and Psychopathology","issn_l":"0954-5794","issn":["0954-5794","1469-2198"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development and Psychopathology","raw_type":"journal-article"},{"id":"pmid:36148872","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36148872","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development and psychopathology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7613991","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7613991","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Dev Psychopathol","raw_type":"Text"},{"id":"pmh:oai:eprints.whiterose.ac.uk:197411","doi":null,"is_oa":true,"landing_page_url":"https://eprints.whiterose.ac.uk/id/eprint/197411/1/gene_environment_interaction_using_polygenic_scores_do_polygenic_scores_for_psychopathology_moderate_predictions_from_environmental_risk_to_behavior_problems.pdf","pdf_url":"https://eprints.whiterose.ac.uk/id/eprint/197411/1/gene_environment_interaction_using_polygenic_scores_do_polygenic_scores_for_psychopathology_moderate_predictions_from_environmental_risk_to_behavior_problems.pdf","source":{"id":"https://openalex.org/S4306400854","display_name":"White Rose Research Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:kclpure.kcl.ac.uk:openaire/e0842dfa-e01d-488f-bbbe-cb31a65875d7","doi":null,"is_oa":true,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/e0842dfa-e01d-488f-bbbe-cb31a65875d7","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Plomin, R, Gidziela, A, Malanchini, M & von Stumm, S 2022, 'Gene-environment interaction using polygenic scores: Do polygenic scores for psychopathology moderate predictions from environmental risk to behavior problems?', Development and Psychopathology, pp. 1-11. https://doi.org/10.1017/S0954579422000931","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:qmro.qmul.ac.uk:123456789/88445","doi":null,"is_oa":true,"landing_page_url":"https://qmro.qmul.ac.uk/xmlui/handle/123456789/88445","pdf_url":null,"source":{"id":"https://openalex.org/S4306400530","display_name":"Queen Mary Research Online (Queen Mary University of London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I166337079","host_organization_name":"Queen Mary University of London","host_organization_lineage":["https://openalex.org/I166337079"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1017/s0954579422000931","doi":"https://doi.org/10.1017/s0954579422000931","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0954579422000931","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/20A7246CEF99EFD0B8EA104983EA127C/S0954579422000931a.pdf/div-class-title-gene-environment-interaction-using-polygenic-scores-do-polygenic-scores-for-psychopathology-moderate-predictions-from-environmental-risk-to-behavior-problems-div.pdf","source":{"id":"https://openalex.org/S6115874","display_name":"Development and Psychopathology","issn_l":"0954-5794","issn":["0954-5794","1469-2198"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","erih-plus","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development and Psychopathology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G4795622352","display_name":"Origins of learning difficulties and behaviour problems: from behavioural genetics to behavioural genomics.","funder_award_id":"MR/M021475/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4296794633.pdf","grobid_xml":"https://content.openalex.org/works/W4296794633.grobid-xml"},"referenced_works_count":84,"referenced_works":["https://openalex.org/W94078271","https://openalex.org/W564195063","https://openalex.org/W582609932","https://openalex.org/W617721604","https://openalex.org/W1829178133","https://openalex.org/W1966758272","https://openalex.org/W1980519570","https://openalex.org/W1991994331","https://openalex.org/W1992204010","https://openalex.org/W1998126202","https://openalex.org/W2004880902","https://openalex.org/W2007537842","https://openalex.org/W2014622153","https://openalex.org/W2020543623","https://openalex.org/W2025664462","https://openalex.org/W2025802167","https://openalex.org/W2031415599","https://openalex.org/W2031725110","https://openalex.org/W2035304341","https://openalex.org/W2040040975","https://openalex.org/W2049023055","https://openalex.org/W2059611659","https://openalex.org/W2061349672","https://openalex.org/W2064192406","https://openalex.org/W2087414280","https://openalex.org/W2088842558","https://openalex.org/W2096360465","https://openalex.org/W2097074714","https://openalex.org/W2099557441","https://openalex.org/W2103768332","https://openalex.org/W2142161268","https://openalex.org/W2144875296","https://openalex.org/W2149016179","https://openalex.org/W2149264570","https://openalex.org/W2153876142","https://openalex.org/W2157729171","https://openalex.org/W2160074632","https://openalex.org/W2162196924","https://openalex.org/W2284729062","https://openalex.org/W2314816382","https://openalex.org/W2346626662","https://openalex.org/W2508866329","https://openalex.org/W2513402838","https://openalex.org/W2735059498","https://openalex.org/W2740637836","https://openalex.org/W2742719784","https://openalex.org/W2758725377","https://openalex.org/W2765638133","https://openalex.org/W2769841767","https://openalex.org/W2782281891","https://openalex.org/W2792787334","https://openalex.org/W2802815532","https://openalex.org/W2806899908","https://openalex.org/W2883573930","https://openalex.org/W2890624363","https://openalex.org/W2903051174","https://openalex.org/W2937611850","https://openalex.org/W2944339144","https://openalex.org/W2951936974","https://openalex.org/W2952197861","https://openalex.org/W2968262757","https://openalex.org/W2971401229","https://openalex.org/W2973631625","https://openalex.org/W2999275395","https://openalex.org/W3004773588","https://openalex.org/W3024217604","https://openalex.org/W3042353117","https://openalex.org/W3045441625","https://openalex.org/W3086322343","https://openalex.org/W3095744893","https://openalex.org/W3107352016","https://openalex.org/W3134017561","https://openalex.org/W3159881528","https://openalex.org/W3160129852","https://openalex.org/W3161467534","https://openalex.org/W3169005485","https://openalex.org/W3173578818","https://openalex.org/W3192494735","https://openalex.org/W3197485676","https://openalex.org/W3198532564","https://openalex.org/W3201845428","https://openalex.org/W3207416862","https://openalex.org/W4200088389","https://openalex.org/W4220711675"],"related_works":["https://openalex.org/W4381377054","https://openalex.org/W4293104711","https://openalex.org/W7133564241","https://openalex.org/W4366819827","https://openalex.org/W4414825140","https://openalex.org/W7046028839","https://openalex.org/W7220679502","https://openalex.org/W3095744893","https://openalex.org/W4414973092","https://openalex.org/W2168088534"],"abstract_inverted_index":{"Abstract":[0],"The":[1,79],"DNA":[2],"revolution":[3],"has":[4],"energized":[5],"research":[6],"on":[7,96],"interactions":[8],"between":[9,44],"genes":[10],"and":[11,40,56,58,69,77,103,111,118,129,136,144,150,178],"environments":[12],"(GxE)":[13],"by":[14],"creating":[15],"indices":[16],"of":[17,25,47,61,100,121,147,159,161,164,176],"G":[18,143,177],"(polygenic":[19],"scores)":[20],"that":[21],"are":[22],"powerful":[23],"predictors":[24],"behavioral":[26],"traits.":[27],"Here,":[28],"we":[29],"test":[30],"the":[31,88,122,173,182],"extent":[32],"to":[33,84,115],"which":[34],"polygenic":[35],"scores":[36],"for":[37,184],"attention-deficit/hyperactivity":[38],"disorder":[39],"neuroticism":[41],"moderate":[42],"associations":[43],"parent":[45],"reports":[46],"their":[48],"children\u2019s":[49],"environmental":[50],"risk":[51],"(E)":[52],"at":[53,73],"ages":[54,74,133],"3":[55],"4":[57],"teacher":[59],"ratings":[60],"behavior":[62,107,126],"problems":[63,127,153],"(hyperactivity/inattention,":[64],"conduct":[65,130],"problems,":[66],"emotional":[67,148],"symptoms,":[68],"peer":[70,151],"relationship":[71,152],"problems)":[72,131],"7,":[75,134],"9":[76,135],"12.":[78],"sampling":[80],"frame":[81],"included":[82],"up":[83,114],"6687":[85],"twins":[86],"from":[87],"Twins":[89],"Early":[90],"Development":[91],"Study.":[92],"Our":[93],"analyses":[94],"focused":[95],"relative":[97],"effect":[98],"sizes":[99],"G,":[101,109],"E":[102,110,145,179],"GxE":[104,112,165],"in":[105,124],"predicting":[106],"problems.":[108],"predicted":[113],"2%,":[116],"2%":[117],"0.4%,":[119],"respectively,":[120],"variance":[123],"externalizing":[125],"(hyperactivity/inattention":[128],"across":[132],"12,":[137],"with":[138],"no":[139],"clear":[140],"developmental":[141],"trends.":[142],"predictions":[146],"symptoms":[149],"were":[154,166],"weaker.":[155],"A":[156],"quarter":[157],"(12":[158],"48)":[160],"our":[162],"tests":[163],"nominally":[167],"significant":[168],"(p":[169],"=":[170],".05).":[171],"Increasing":[172],"predictive":[174],"power":[175],"would":[180],"enhance":[181],"search":[183],"GxE.":[185]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2022-09-24T00:00:00"}