{"id":"https://openalex.org/W4296546737","doi":"https://doi.org/10.1080/10408398.2022.2119931","title":"Insoluble dietary fibers: structure, metabolism, interactions with human microbiome, and role in gut homeostasis","display_name":"Insoluble dietary fibers: structure, metabolism, interactions with human microbiome, and role in gut homeostasis","publication_year":2022,"publication_date":"2022-09-12","ids":{"openalex":"https://openalex.org/W4296546737","doi":"https://doi.org/10.1080/10408398.2022.2119931","pmid":"https://pubmed.ncbi.nlm.nih.gov/36094440"},"language":"en","primary_location":{"id":"doi:10.1080/10408398.2022.2119931","doi":"https://doi.org/10.1080/10408398.2022.2119931","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10408398.2022.2119931","pdf_url":null,"source":{"id":"https://openalex.org/S70620193","display_name":"Critical Reviews in Food Science and Nutrition","issn_l":"1040-8398","issn":["1040-8398","1549-7852"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Reviews in Food Science and Nutrition","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073372439","display_name":"Mostafa H. Baky","orcid":"https://orcid.org/0000-0002-8597-7974","observed_orcids":["https://orcid.org/0000-0002-8597-7974"]},"institutions":[{"id":"https://openalex.org/I67337280","display_name":"Egyptian Russian University","ror":"https://ror.org/029me2q51","country_code":"EG","type":"education","lineage":["https://openalex.org/I67337280"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mostafa H. Baky","raw_affiliation_strings":["Pharmacognosy Department, College of Pharmacy, Egyptian Russian University, Badr City, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacognosy Department, College of Pharmacy, Egyptian Russian University, Badr City, Egypt","institution_ids":["https://openalex.org/I67337280"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mohamed Salah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I88017793","display_name":"Port Said University","ror":"https://ror.org/01vx5yq44","country_code":"EG","type":"education","lineage":["https://openalex.org/I88017793"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mohamed Salah","raw_affiliation_strings":["Microbiology Department, College of Pharmacy, Port Said University, Port Said, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology Department, College of Pharmacy, Port Said University, Port Said, Egypt","institution_ids":["https://openalex.org/I88017793"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041707474","display_name":"Nada M. Ezzelarab","orcid":"https://orcid.org/0000-0001-7992-7260","observed_orcids":["https://orcid.org/0000-0001-7992-7260"]},"institutions":[{"id":"https://openalex.org/I80693520","display_name":"American University in Cairo","ror":"https://ror.org/0176yqn58","country_code":"EG","type":"education","lineage":["https://openalex.org/I80693520"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Nada Ezzelarab","raw_affiliation_strings":["Biology Department, School of Sciences & Engineering, The American University in Cairo, New Cairo, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, School of Sciences & Engineering, The American University in Cairo, New Cairo, Egypt","institution_ids":["https://openalex.org/I80693520"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029701714","display_name":"Ping Shao","orcid":"https://orcid.org/0000-0001-7078-7003","observed_orcids":["https://orcid.org/0000-0001-7078-7003"]},"institutions":[{"id":"https://openalex.org/I55712492","display_name":"Zhejiang University of Technology","ror":"https://ror.org/02djqfd08","country_code":"CN","type":"education","lineage":["https://openalex.org/I55712492"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Shao","raw_affiliation_strings":["Department of Food Science and Technology, Zhejiang University of Technology, Zhejiang, Hangzhou, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science and Technology, Zhejiang University of Technology, Zhejiang, Hangzhou, PR China","institution_ids":["https://openalex.org/I55712492"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038529807","display_name":"Mostafa S. Elshahed","orcid":"https://orcid.org/0000-0002-1067-1647","observed_orcids":["https://orcid.org/0000-0002-1067-1647"]},"institutions":[{"id":"https://openalex.org/I115475287","display_name":"Oklahoma State University","ror":"https://ror.org/01g9vbr38","country_code":"US","type":"education","lineage":["https://openalex.org/I115475287"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mostafa S. Elshahed","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA","institution_ids":["https://openalex.org/I115475287"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028476979","display_name":"Mohamed Ali Farag","orcid":"https://orcid.org/0000-0001-5139-1863","observed_orcids":["https://orcid.org/0000-0001-5139-1863"]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Mohamed A. Farag","raw_affiliation_strings":["Pharmacognosy Department, College of Pharmacy, Cairo University, Cairo, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacognosy Department, College of Pharmacy, Cairo University, Cairo, Egypt","institution_ids":["https://openalex.org/I145487455"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5028476979"],"corresponding_institution_ids":["https://openalex.org/I145487455"],"apc_list":null,"apc_paid":null,"fwci":1.9912,"has_fulltext":false,"cited_by_count":114,"citation_normalized_percentile":{"value":0.9027642,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"64","issue":"7","first_page":"1954","last_page":"1968"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.5590999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.5590999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10140","display_name":"Food composition and properties","score":0.4081999957561493,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12489","display_name":"Microbial Metabolites in Food Biotechnology","score":0.028699999675154686,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/insoluble-dietary-fiber","display_name":"insoluble dietary fiber","score":0.9079999923706055},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.824999988079071},{"id":"https://openalex.org/keywords/intestinal-homeostasis","display_name":"intestinal homeostasis","score":0.9610000252723694},{"id":"https://openalex.org/keywords/cellulose","display_name":"cellulose","score":0.8619999885559082},{"id":"https://openalex.org/keywords/hemicellulose","display_name":"hemicellulose","score":1.0},{"id":"https://openalex.org/keywords/resistant-starch","display_name":"resistant starch","score":0.996999979019165},{"id":"https://openalex.org/keywords/lignin","display_name":"lignin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/intestinal-immunity","display_name":"intestinal immunity","score":0.6930000185966492},{"id":"https://openalex.org/keywords/intestinal-barrier-integrity","display_name":"intestinal barrier integrity","score":0.8550000190734863},{"id":"https://openalex.org/keywords/probiotic-adhesion","display_name":"probiotic adhesion","score":0.9660000205039978},{"id":"https://openalex.org/keywords/functional-foods","display_name":"functional foods","score":0.8169999718666077},{"id":"https://openalex.org/keywords/food-industry-by-products","display_name":"food by-products","score":0.5299999713897705},{"id":"https://openalex.org/keywords/pathogen-colonization","display_name":"pathogen colonization","score":0.6759999990463257}],"concepts":[{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.5184525847434998},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.5138056874275208},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47148796916007996},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11620837450027466},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.10597863793373108}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004043","descriptor_name":"Dietary Fiber","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1080/10408398.2022.2119931","doi":"https://doi.org/10.1080/10408398.2022.2119931","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10408398.2022.2119931","pdf_url":null,"source":{"id":"https://openalex.org/S70620193","display_name":"Critical Reviews in Food Science and Nutrition","issn_l":"1040-8398","issn":["1040-8398","1549-7852"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Reviews in Food Science and Nutrition","raw_type":"journal-article"},{"id":"pmid:36094440","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36094440","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical reviews in food science and nutrition","raw_type":"Review"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":97,"referenced_works":["https://openalex.org/W1969735171","https://openalex.org/W1969954634","https://openalex.org/W1971135240","https://openalex.org/W1975758482","https://openalex.org/W2000952387","https://openalex.org/W2002940994","https://openalex.org/W2032319408","https://openalex.org/W2038293079","https://openalex.org/W2045654294","https://openalex.org/W2050441581","https://openalex.org/W2056397579","https://openalex.org/W2076953752","https://openalex.org/W2084037262","https://openalex.org/W2089633816","https://openalex.org/W2098039321","https://openalex.org/W2098149200","https://openalex.org/W2098614291","https://openalex.org/W2099740349","https://openalex.org/W2100829837","https://openalex.org/W2109792269","https://openalex.org/W2115581755","https://openalex.org/W2116350924","https://openalex.org/W2126991474","https://openalex.org/W2142537875","https://openalex.org/W2142871107","https://openalex.org/W2146860605","https://openalex.org/W2150916966","https://openalex.org/W2167008140","https://openalex.org/W2168842536","https://openalex.org/W2171697053","https://openalex.org/W2235429139","https://openalex.org/W2254321658","https://openalex.org/W2291477483","https://openalex.org/W2305325432","https://openalex.org/W2401555166","https://openalex.org/W2404378559","https://openalex.org/W2464380244","https://openalex.org/W2467528364","https://openalex.org/W2512643090","https://openalex.org/W2525923213","https://openalex.org/W2553392328","https://openalex.org/W2585111741","https://openalex.org/W2599579733","https://openalex.org/W2621268362","https://openalex.org/W2626935023","https://openalex.org/W2732274229","https://openalex.org/W2754317298","https://openalex.org/W2755513907","https://openalex.org/W2759505346","https://openalex.org/W2765206455","https://openalex.org/W2771965785","https://openalex.org/W2774174297","https://openalex.org/W2777228601","https://openalex.org/W2781217172","https://openalex.org/W2790374493","https://openalex.org/W2793178934","https://openalex.org/W2799897236","https://openalex.org/W2803293884","https://openalex.org/W2890786626","https://openalex.org/W2894471192","https://openalex.org/W2895397659","https://openalex.org/W2903653104","https://openalex.org/W2904355230","https://openalex.org/W2906309239","https://openalex.org/W2907097889","https://openalex.org/W2909668868","https://openalex.org/W2910667514","https://openalex.org/W2913634276","https://openalex.org/W2914018305","https://openalex.org/W2915393868","https://openalex.org/W2924868976","https://openalex.org/W2938915280","https://openalex.org/W2944690368","https://openalex.org/W2948431467","https://openalex.org/W2969258672","https://openalex.org/W2969434506","https://openalex.org/W2979668360","https://openalex.org/W2984746109","https://openalex.org/W2985523803","https://openalex.org/W2986031300","https://openalex.org/W2991084977","https://openalex.org/W2999593906","https://openalex.org/W3019088644","https://openalex.org/W3026412632","https://openalex.org/W3081971156","https://openalex.org/W3089835816","https://openalex.org/W3156820397","https://openalex.org/W3158601927","https://openalex.org/W3159041877","https://openalex.org/W3176811053","https://openalex.org/W3196884658","https://openalex.org/W3199864063","https://openalex.org/W3201647445","https://openalex.org/W3203029982","https://openalex.org/W3205027920","https://openalex.org/W4206067569","https://openalex.org/W4248866015"],"related_works":["https://openalex.org/W4406705045","https://openalex.org/W7134947333","https://openalex.org/W4293090209","https://openalex.org/W2969232541","https://openalex.org/W4409363492","https://openalex.org/W7067815975","https://openalex.org/W3214085000","https://openalex.org/W4292481014","https://openalex.org/W4403512470","https://openalex.org/W3001232849"],"abstract_inverted_index":{"Consumption":[0],"of":[1,41,58,70,74,92,110,129,167,182,214],"food":[2,145,203],"rich":[3],"in":[4,144,205],"dietary":[5,192],"fibers":[6,193,216],"(DFs)":[7],"has":[8],"been":[9],"long":[10],"recognized":[11],"to":[12,24,154,178,199,207],"exert":[13],"an":[14,68],"overall":[15,126],"beneficial":[16],"effect":[17],"on":[18,29,94,112],"human":[19,33,103,172],"health.":[20,173],"This":[21],"review":[22],"aims":[23],"provide":[25],"a":[26],"holistic":[27],"overview":[28,69],"how":[30],"IDFs":[31,77,93,111,130,134,151,175],"impact":[32,91,109],"gut":[34,43,83,104,113,156],"health":[35],"either":[36],"directly,":[37],"or":[38],"through":[39],"modulation":[40],"the":[42,71,75,79,102,108,119,125,180,209],"microbiome.":[44],"Several":[45],"databases":[46],"were":[47,132,152,176],"searched":[48],"for":[49,85,148],"collecting":[50],"papers":[51],"such":[52],"as":[53,122,124],"PubMed,":[54],"Google":[55],"Scholar,":[56],"Web":[57],"Science,":[59],"Scopus":[60],"and":[61,78,98,115,140,161,164,169,185,212,217],"Reaxys":[62],"from":[63],"2000":[64],"till":[65],"2022.":[66],"Firstly,":[67],"chemical":[72],"structure":[73,97],"various":[76],"pathways":[80],"employed":[81],"by":[82,195],"microbiota":[84],"their":[86,187,218],"degradation":[87],"is":[88],"provided.":[89],"The":[90],"microbial":[95],"community":[96],"pathogens":[99],"colonization":[100],"inside":[101],"was":[105],"discussed.":[106],"Finally,":[107],"homeostasis":[114],"systemic":[116],"effects":[117],"at":[118],"cellular":[120],"level,":[121],"well":[123],"immunological":[127],"benefits":[128],"consumption":[131],"analyzed.":[133],"viz.,":[135],"cellulose,":[136],"hemicellulose,":[137],"resistant":[138],"starch,":[139],"lignin":[141],"found":[142,153],"enriched":[143],"are":[146],"discussed":[147],"these":[149],"effects.":[150],"induce":[155],"immunity,":[157],"improve":[158,171,179,186],"intestinal":[159],"integrity":[160],"mucosal":[162],"proliferation,":[163],"favor":[165],"adhesion":[166],"probiotics":[168],"hence":[170],"Also,":[174],"concluded":[177],"bioavailability":[181],"plant":[183],"polyphenols":[184],"health-related":[188],"functional":[189,202],"roles.":[190],"Ultimately,":[191],"processing":[194],"modification":[196],"shows":[197],"potential":[198],"enhance":[200],"fibers-based":[201],"production,":[204],"addition":[206],"increase":[208],"economic":[210],"value":[211],"usage":[213],"food-rich":[215],"by-products.":[219]},"counts_by_year":[{"year":2026,"cited_by_count":35},{"year":2025,"cited_by_count":34},{"year":2024,"cited_by_count":35},{"year":2023,"cited_by_count":10}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-09-21T00:00:00"}
