{"id":"https://openalex.org/W4296479312","doi":"https://doi.org/10.1093/mmy/myac072.p286","title":"P286 Histoplasmosis in Sri Lanka","display_name":"P286 Histoplasmosis in Sri Lanka","publication_year":2022,"publication_date":"2022-09-01","ids":{"openalex":"https://openalex.org/W4296479312","doi":"https://doi.org/10.1093/mmy/myac072.p286"},"language":"en","primary_location":{"id":"doi:10.1093/mmy/myac072.p286","doi":"https://doi.org/10.1093/mmy/myac072.p286","is_oa":true,"landing_page_url":"https://doi.org/10.1093/mmy/myac072.p286","pdf_url":null,"source":{"id":"https://openalex.org/S93288122","display_name":"Medical Mycology","issn_l":"0268-1218","issn":["0268-1218","1365-280X","1369-3786","1460-2709"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Mycology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1093/mmy/myac072.p286","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062988639","display_name":"L. S. M. Sigera","orcid":"https://orcid.org/0000-0002-5519-7619","observed_orcids":["https://orcid.org/0000-0002-5519-7619"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Liyanage Shamithra Madhumali Sigera","raw_affiliation_strings":["Manchester Fungal Infection Group , Core Technology Facility, University of Manchester, Manchester , United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Fungal Infection Group , Core Technology Facility, University of Manchester, Manchester , United Kingdom","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066644201","display_name":"Primali I. Jayasekera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144322","display_name":"Medical Research Institute","ror":"https://ror.org/0582gcw47","country_code":"LK","type":"healthcare","lineage":["https://openalex.org/I4210144322"]}],"countries":["LK"],"is_corresponding":false,"raw_author_name":"Primali I Jayasekera","raw_affiliation_strings":["Department of Mycology , Medical Research Institute, Colombo , Sri Lanka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mycology , Medical Research Institute, Colombo , Sri Lanka","institution_ids":["https://openalex.org/I4210144322"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083752740","display_name":"David W. Denning","orcid":"https://orcid.org/0000-0001-5626-2251","observed_orcids":["https://orcid.org/0000-0001-5626-2251","https://orcid.org/0000-0002-0955-0151"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David W Denning","raw_affiliation_strings":["Manchester Fungal Infection Group , Core Technology Facility, University of Manchester, Manchester , United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Fungal Infection Group , Core Technology Facility, University of Manchester, Manchester , United Kingdom","institution_ids":["https://openalex.org/I28407311"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4477,"currency":"USD","value_usd":4477},"apc_paid":{"value":4477,"currency":"USD","value_usd":4477},"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"60","issue":"Supplement_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11909","display_name":"Histiocytic Disorders and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/histoplasmosis","display_name":"histoplasmosis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/histoplasma-capsulatum","display_name":"Histoplasma capsulatum","score":0.996999979019165},{"id":"https://openalex.org/keywords/sri-lanka","display_name":"Sri Lanka","score":0.9850000143051147},{"id":"https://openalex.org/keywords/oral-histoplasmosis","display_name":"oral histoplasmosis","score":0.9150000214576721},{"id":"https://openalex.org/keywords/histoplasmin-skin-test","display_name":"histoplasmin skin test","score":0.8479999899864197},{"id":"https://openalex.org/keywords/disseminated-histoplasmosis","display_name":"disseminated histoplasmosis","score":0.902999997138977},{"id":"https://openalex.org/keywords/oral-lesions","display_name":"oral lesions","score":0.5189999938011169},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.5070000290870667},{"id":"https://openalex.org/keywords/betel-nut-chewing","display_name":"betel quid chewing","score":0.996999979019165},{"id":"https://openalex.org/keywords/itraconazole","display_name":"itraconazole","score":0.8159999847412109},{"id":"https://openalex.org/keywords/amphotericin-b","display_name":"amphotericin B","score":0.996999979019165},{"id":"https://openalex.org/keywords/endemic-fungal-infection","display_name":"endemic fungal infection","score":0.5270000100135803},{"id":"https://openalex.org/keywords/clinical-characteristics","display_name":"clinical features","score":0.45399999618530273}],"concepts":[{"id":"https://openalex.org/C2780318139","wikidata":"https://www.wikidata.org/wiki/Q627625","display_name":"Histoplasmosis","level":2,"score":0.9409880638122559},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6615663766860962},{"id":"https://openalex.org/C2778803964","wikidata":"https://www.wikidata.org/wiki/Q143747","display_name":"Histoplasma capsulatum","level":3,"score":0.5909426808357239},{"id":"https://openalex.org/C2777802930","wikidata":"https://www.wikidata.org/wiki/Q10941019","display_name":"Histoplasma","level":4,"score":0.5793046355247498},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.5324315428733826},{"id":"https://openalex.org/C3017649214","wikidata":"https://www.wikidata.org/wiki/Q854","display_name":"Sri lanka","level":3,"score":0.49011024832725525},{"id":"https://openalex.org/C2780908437","wikidata":"https://www.wikidata.org/wiki/Q464067","display_name":"Mycosis","level":2,"score":0.4809786081314087},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3903142511844635},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.323161244392395},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.22481590509414673},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.13629552721977234},{"id":"https://openalex.org/C2779357621","wikidata":"https://www.wikidata.org/wiki/Q655495","display_name":"Tanzania","level":2,"score":0.10065996646881104},{"id":"https://openalex.org/C91375879","wikidata":"https://www.wikidata.org/wiki/Q15473274","display_name":"Environmental planning","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/mmy/myac072.p286","doi":"https://doi.org/10.1093/mmy/myac072.p286","is_oa":true,"landing_page_url":"https://doi.org/10.1093/mmy/myac072.p286","pdf_url":null,"source":{"id":"https://openalex.org/S93288122","display_name":"Medical Mycology","issn_l":"0268-1218","issn":["0268-1218","1365-280X","1369-3786","1460-2709"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Mycology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9509929","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9509929","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Med Mycol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/mmy/myac072.p286","doi":"https://doi.org/10.1093/mmy/myac072.p286","is_oa":true,"landing_page_url":"https://doi.org/10.1093/mmy/myac072.p286","pdf_url":null,"source":{"id":"https://openalex.org/S93288122","display_name":"Medical Mycology","issn_l":"0268-1218","issn":["0268-1218","1365-280X","1369-3786","1460-2709"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Mycology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4381743719","https://openalex.org/W2087563322","https://openalex.org/W4389769121","https://openalex.org/W2022061726","https://openalex.org/W7202154803","https://openalex.org/W2340995118","https://openalex.org/W7162293060","https://openalex.org/W3025964726","https://openalex.org/W2005442877","https://openalex.org/W4378232291"],"abstract_inverted_index":{"Abstract":[0],"Poster":[1],"session":[2],"2,":[3],"September":[4],"22,":[5],"2022,":[6],"12:30":[7],"PM":[8,11],"-":[9],"1:30":[10],"Background":[12],"Histoplasmosis":[13,54,325],"is":[14,55,68],"a":[15,22,49],"systemic":[16],"mycosis":[17],"caused":[18],"by":[19],"Histoplasma":[20],"capsulatum,":[21],"dimorphic":[23],"fungus.":[24],"More":[25],"severe":[26],"disease":[27],"has":[28],"been":[29,154],"observed":[30,141,155,197],"in":[31,37,58,77,156,174,198,248,327,347,363],"immunocompromised":[32],"individuals.":[33],"Most":[34,176],"cases":[35,67,94,134,195,333],"occur":[36],"certain":[38],"endemic":[39],"regions":[40],"of":[41,64,74,127,135,148,150,159,167,177,210,238,250,279,300,318,332,360],"the":[42,62,78,121,143,157,168,171,178,183,188,201,205,251,280,295,298,316,319,345,358],"world":[43],"however":[44,253],"it":[45],"seems":[46],"to":[47,86,241,271,337],"have":[48],"much":[50,339],"wider":[51],"global":[52],"distribution.":[53],"infrequently":[56],"recognized":[57],"Sri":[59,138,164,328,364],"Lanka":[60,139],"and":[61,115,132,170,204,217,236,257,266,277,288,302,310,356],"dispersion":[63],"information":[65],"on":[66,108],"fragmented.":[69],"Method":[70],"The":[71,208,223,330],"comprehensive":[72],"search":[73],"medical":[75,361],"literature":[76],"English":[79],"language":[80],"through":[81],"databases":[82],"from":[83,182,227],"any":[84],"time":[85],"February":[87],"2022.":[88],"Either,":[89],"culture-proven":[90],"or":[91],"histopathologically":[92],"proven":[93],"were":[95,103,118,140,180,196,213,220,282,292,305,313],"selected":[96],"as":[97],"diagnostically":[98],"confirmed":[99],"histoplasmosis.":[100],"Duplicate":[101],"reports":[102],"excluded.":[104],"All":[105],"available":[106],"data":[107],"demography,":[109],"clinical":[110,116,224],"presentation,":[111],"diagnostic":[112,354],"method,":[113],"management,":[114],"outcome":[117],"appraised":[119],"for":[120,284,294,315],"reported":[122,181,342],"cases.":[123],"Result":[124],"One":[125],"survey":[126,158],"histoplasmin":[128,151,160,190],"skin":[129,234],"sensitivity":[130,161],"testing":[131,304],"ten":[133],"histoplasmosis":[136,245,260,276],"across":[137],"during":[142],"above":[144],"period.":[145],"A":[146],"total":[147],"5.7%":[149],"positivity":[152],"had":[153,187],"among":[162],"1366":[163],"Lankan":[165],"volunteers":[166],"Western":[169],"Central":[172,184],"Provinces":[173],"1969.":[175],"patients":[179,219,252,281,320],"province":[185],"which":[186],"positive":[189,283],"test":[191],"previously.":[192],"In":[193],"addition,":[194],"Southern":[199],"Province,":[200,203],"Sabragamuwa":[202],"Eastern":[206],"Province.":[207],"majority":[209],"affected":[211],"individuals":[212],"adult":[214],"males":[215],"(90%)":[216],"pediatric":[218],"not":[221,262,306],"observed.":[222,263],"presentation":[225],"stretched":[226],"oral":[228,275],"lesions":[229],"(the":[230],"most":[231],"common":[232],"presentation),":[233],"lesions,":[235],"fever":[237],"unknown":[239],"origin,":[240],"adrenal":[242],"crisis.":[243],"Disseminated":[244],"was":[246,261],"diagnosed":[247],"50%":[249],"asymptomatic,":[254],"acute":[255],"pulmonary,":[256],"chronic":[258],"pulmonary":[259],"Both":[264,286,308],"diabetes":[265],"betel":[267],"chewing":[268],"are":[269],"likely":[270],"be":[272,335,338],"linked":[273],"with":[274,321,344],"none":[278],"HIV.":[285],"histopathology":[287],"fungal":[289],"culture":[290],"methods":[291],"used":[293,314],"diagnosis":[296],"while":[297],"use":[299],"antigen":[301],"antibody":[303],"popular.":[307],"itraconazole":[309],"amphotericin":[311],"B":[312],"treatment":[317],"variable":[322],"outcomes.":[323],"Conclusion":[324],"exists":[326],"Lanka.":[329,365],"number":[331],"could":[334],"expected":[336],"higher":[340],"than":[341],"along":[343],"increase":[346,357],"at-risk":[348],"populations.":[349],"These":[350],"mandates":[351],"enhance":[352],"laboratory":[353],"facilities":[355],"awareness":[359],"professionals":[362]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2022-09-21T00:00:00"}