{"id":"https://openalex.org/W4296311446","doi":"https://doi.org/10.1016/j.crbiot.2022.09.004","title":"A systematic analysis of biotech startups that went public in the first half of 2021","display_name":"A systematic analysis of biotech startups that went public in the first half of 2021","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4296311446","doi":"https://doi.org/10.1016/j.crbiot.2022.09.004"},"language":"en","primary_location":{"id":"doi:10.1016/j.crbiot.2022.09.004","doi":"https://doi.org/10.1016/j.crbiot.2022.09.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.crbiot.2022.09.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2590262822000326/pdf","source":{"id":"https://openalex.org/S4210236447","display_name":"Current Research in Biotechnology","issn_l":"2590-2628","issn":["2590-2628"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Research in Biotechnology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["arxiv","crossref","datacite","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S2590262822000326/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070268860","display_name":"Sebastian G. Huayamares","orcid":"https://orcid.org/0000-0003-2859-3074","observed_orcids":["https://orcid.org/0000-0003-2859-3074"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]},{"id":"https://openalex.org/I2802612298","display_name":"The Wallace H. Coulter Department of Biomedical Engineering","ror":"https://ror.org/02j15s898","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sebastian G. Huayamares","raw_affiliation_strings":["Quantitative & Computational Finance Program, Georgia Institute of Technology, Atlanta, GA, 30332, USA","Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory School of Medicine, Atlanta, GA, 30332, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Quantitative & Computational Finance Program, Georgia Institute of Technology, Atlanta, GA, 30332, USA","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory School of Medicine, Atlanta, GA, 30332, USA","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I2802612298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081929582","display_name":"Melissa P. Lokugamage","orcid":"https://orcid.org/0000-0001-7064-5021","observed_orcids":["https://orcid.org/0000-0001-7064-5021"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Melissa P. Lokugamage","raw_affiliation_strings":["Alloy Therapeutics, Boston, MA, 02421, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alloy Therapeutics, Boston, MA, 02421, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030284586","display_name":"Alejandro J. Da Silva Sanchez","orcid":"https://orcid.org/0009-0005-7476-5406","observed_orcids":["https://orcid.org/0009-0005-7476-5406"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alejandro J. Da Silva Sanchez","raw_affiliation_strings":["Department of Chemical Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA","Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA","Quantitative & Computational Finance Program, Georgia Institute of Technology, Atlanta, GA, 30332, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Quantitative & Computational Finance Program, Georgia Institute of Technology, Atlanta, GA, 30332, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036723734","display_name":"James E. Dahlman","orcid":"https://orcid.org/0000-0001-7580-436X","observed_orcids":["https://orcid.org/0000-0001-7580-436X"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]},{"id":"https://openalex.org/I2802612298","display_name":"The Wallace H. Coulter Department of Biomedical Engineering","ror":"https://ror.org/02j15s898","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James E. Dahlman","raw_affiliation_strings":["Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory School of Medicine, Atlanta, GA, 30332, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory School of Medicine, Atlanta, GA, 30332, USA","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I2802612298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5070268860"],"corresponding_institution_ids":["https://openalex.org/I130701444","https://openalex.org/I2802612298"],"apc_list":{"value":2500,"currency":"USD","value_usd":2500},"apc_paid":{"value":2500,"currency":"USD","value_usd":2500},"fwci":1.6885,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.86326815,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"4","issue":null,"first_page":"392","last_page":"401"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11903","display_name":"Private Equity and Venture Capital","score":0.8422999978065491,"subfield":{"id":"https://openalex.org/subfields/2003","display_name":"Finance"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11903","display_name":"Private Equity and Venture Capital","score":0.8422999978065491,"subfield":{"id":"https://openalex.org/subfields/2003","display_name":"Finance"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T14293","display_name":"Biotechnology and Related Fields","score":0.11400000005960464,"subfield":{"id":"https://openalex.org/subfields/1405","display_name":"Management of Technology and Innovation"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11792","display_name":"Pharmaceutical Economics and Policy","score":0.015599999576807022,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biotechnology-startups","display_name":"biotechnology startups","score":0.9950000047683716},{"id":"https://openalex.org/keywords/initial-public-offerings","display_name":"initial public offerings","score":0.9610000252723694},{"id":"https://openalex.org/keywords/startup-leadership","display_name":"startup leadership","score":0.7089999914169312},{"id":"https://openalex.org/keywords/clinical-trials","display_name":"clinical trials","score":0.7799999713897705},{"id":"https://openalex.org/keywords/intellectual-property","display_name":"intellectual property","score":0.9850000143051147},{"id":"https://openalex.org/keywords/post-ipo-stock-performance","display_name":"post-IPO stock performance","score":0.9940000176429749},{"id":"https://openalex.org/keywords/commercialization-of-biotechnology","display_name":"biotechnology commercialization","score":0.699999988079071}],"concepts":[{"id":"https://openalex.org/C12559387","wikidata":"https://www.wikidata.org/wiki/Q185142","display_name":"Initial public offering","level":2,"score":0.9771378040313721},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.5298091173171997},{"id":"https://openalex.org/C34974158","wikidata":"https://www.wikidata.org/wiki/Q131257","display_name":"Intellectual property","level":2,"score":0.5112733840942383},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.48312661051750183},{"id":"https://openalex.org/C121955636","wikidata":"https://www.wikidata.org/wiki/Q4116214","display_name":"Accounting","level":1,"score":0.30718955397605896},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.2309846580028534},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20008710026741028},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.1261969804763794}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1016/j.crbiot.2022.09.004","doi":"https://doi.org/10.1016/j.crbiot.2022.09.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.crbiot.2022.09.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2590262822000326/pdf","source":{"id":"https://openalex.org/S4210236447","display_name":"Current Research in Biotechnology","issn_l":"2590-2628","issn":["2590-2628"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Research in Biotechnology","raw_type":"journal-article"},{"id":"pmh:oai:RePEc:arx:papers:2205.00993","doi":null,"is_oa":false,"landing_page_url":"http://arxiv.org/pdf/2205.00993","pdf_url":"http://arxiv.org/pdf/2205.00993","source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"preprint"},{"id":"pmh:oai:arXiv.org:2205.00993","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/2205.00993","pdf_url":"https://arxiv.org/pdf/2205.00993","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:doaj.org/article:c30e2096e5a040c5a8036c87302a70c8","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c30e2096e5a040c5a8036c87302a70c8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Current Research in Biotechnology, Vol 4, Iss , Pp 392-401 (2022)","raw_type":"article"},{"id":"doi:10.48550/arxiv.2205.00993","doi":"https://doi.org/10.48550/arxiv.2205.00993","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2205.00993","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1016/j.crbiot.2022.09.004","doi":"https://doi.org/10.1016/j.crbiot.2022.09.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.crbiot.2022.09.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2590262822000326/pdf","source":{"id":"https://openalex.org/S4210236447","display_name":"Current Research in Biotechnology","issn_l":"2590-2628","issn":["2590-2628"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Research in Biotechnology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332963","display_name":"Allos Therapeutics","ror":"https://ror.org/050473r14"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4296311446.pdf","grobid_xml":"https://content.openalex.org/works/W4296311446.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1504933094","https://openalex.org/W2002791789","https://openalex.org/W2057259827","https://openalex.org/W2078890343","https://openalex.org/W2083511086","https://openalex.org/W2096087337","https://openalex.org/W2567424265","https://openalex.org/W2806834952","https://openalex.org/W2898191328","https://openalex.org/W2965533623","https://openalex.org/W2983293026","https://openalex.org/W3011647955","https://openalex.org/W3094492244","https://openalex.org/W3111084320","https://openalex.org/W3111094104","https://openalex.org/W3111255098","https://openalex.org/W3112179900","https://openalex.org/W3113150977","https://openalex.org/W3113734454","https://openalex.org/W3119456445","https://openalex.org/W3121299736","https://openalex.org/W3121662999","https://openalex.org/W3122865358","https://openalex.org/W3123237382","https://openalex.org/W3125794209","https://openalex.org/W3133614619","https://openalex.org/W3134221148","https://openalex.org/W3141401153","https://openalex.org/W3159469843","https://openalex.org/W3164039743","https://openalex.org/W3181226580","https://openalex.org/W3199141540","https://openalex.org/W3214472150","https://openalex.org/W4205379795","https://openalex.org/W4213048306","https://openalex.org/W4214606122","https://openalex.org/W6798165554"],"related_works":["https://openalex.org/W2035434000","https://openalex.org/W2143615526","https://openalex.org/W2062118912","https://openalex.org/W3109157109","https://openalex.org/W4286620769","https://openalex.org/W6988661787","https://openalex.org/W4311897891","https://openalex.org/W2008312543","https://openalex.org/W2750919262","https://openalex.org/W3019297812"],"abstract_inverted_index":{"Biotechnologies":[0],"are":[1],"being":[2],"commercialized":[3],"at":[4],"historic":[5],"rates.":[6],"In":[7,48,116],"2020,":[8],"74":[9],"biotech":[10,39,79,97,126],"startups":[11,40],"went":[12,22],"public":[13,17],"through":[14,23],"an":[15,59],"initial":[16],"offering":[18],"(IPO)":[19],"and":[20,75,90,111],"60":[21],"the":[24,28,35,62,69,109,124,133],"IPO":[25,60],"process":[26],"in":[27,61,86,128],"first":[29,63],"six":[30],"months":[31],"of":[32,55,65,77],"2021.":[33,66],"However,":[34],"traits":[36,119],"associated":[37],"with":[38],"obtaining":[41],"recent":[42],"IPOs":[43,127],"have":[44],"not":[45,139],"been":[46],"reported.":[47],"this":[49],"study,":[50],"we":[51,81],"built":[52],"a":[53],"database":[54],"biotechs":[56],"that":[57,83,103,132],"underwent":[58],"half":[64],"After":[67],"analyzing":[68],"leadership,":[70,87],"technological":[71],"focus,":[72],"clinical":[73,88],"trials,":[74,89],"financing":[76],"these":[78,118],"startups,":[80],"found":[82],"advanced":[84],"degrees":[85],"intellectual":[91],"property":[92],"were":[93,120,138],"important":[94],"factors":[95],"for":[96,136],"startups.":[98],"The":[99],"data":[100,134],"also":[101],"suggested":[102],"large":[104],"private":[105],"rounds":[106],"could":[107],"decrease":[108],"time-to-IPO":[110],"affect":[112],"post-IPO":[113],"stock":[114],"performance.":[115],"particular,":[117],"often":[121],"exhibited":[122],"by":[123,142],"108":[125],"2018\u20132019,":[129],"thereby":[130],"suggesting":[131],"obtained":[135],"2021":[137],"necessarily":[140],"driven":[141],"COVID-19.":[143]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2022-09-20T00:00:00"}