{"id":"https://openalex.org/W4296142811","doi":"https://doi.org/10.1016/j.neubiorev.2022.104880","title":"Multi-system responses to altered gravity and spaceflight: Insights from Drosophila melanogaster","display_name":"Multi-system responses to altered gravity and spaceflight: Insights from Drosophila melanogaster","publication_year":2022,"publication_date":"2022-09-17","ids":{"openalex":"https://openalex.org/W4296142811","doi":"https://doi.org/10.1016/j.neubiorev.2022.104880","pmid":"https://pubmed.ncbi.nlm.nih.gov/36126744"},"language":"en","primary_location":{"id":"doi:10.1016/j.neubiorev.2022.104880","doi":"https://doi.org/10.1016/j.neubiorev.2022.104880","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neubiorev.2022.104880","pdf_url":null,"source":{"id":"https://openalex.org/S170052170","display_name":"Neuroscience & Biobehavioral Reviews","issn_l":"0149-7634","issn":["0149-7634","1873-7528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience & Biobehavioral Reviews","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.neubiorev.2022.104880","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042976541","display_name":"Janani S. Iyer","orcid":"https://orcid.org/0000-0003-0666-9744","observed_orcids":["https://orcid.org/0000-0003-0666-9744"]},"institutions":[{"id":"https://openalex.org/I1280536761","display_name":"Ames Research Center","ror":"https://ror.org/02acart68","country_code":"US","type":"facility","lineage":["https://openalex.org/I1280536761","https://openalex.org/I4210124779"]},{"id":"https://openalex.org/I1329765538","display_name":"Universities Space Research Association","ror":"https://ror.org/043pgqy52","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1329765538"]},{"id":"https://openalex.org/I4210124779","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80","country_code":"US","type":"government","lineage":["https://openalex.org/I4210124779"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janani Iyer","raw_affiliation_strings":["Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA; Universities Space Research Association, Columbia, MD 21046, USA; KBR, Houston, TX 77002, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA; Universities Space Research Association, Columbia, MD 21046, USA; KBR, Houston, TX 77002, USA","institution_ids":["https://openalex.org/I1280536761","https://openalex.org/I1329765538","https://openalex.org/I4210124779"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084017003","display_name":"Siddhita D. Mhatre","orcid":"https://orcid.org/0000-0001-9939-780X","observed_orcids":["https://orcid.org/0000-0001-9939-780X"]},"institutions":[{"id":"https://openalex.org/I1280536761","display_name":"Ames Research Center","ror":"https://ror.org/02acart68","country_code":"US","type":"facility","lineage":["https://openalex.org/I1280536761","https://openalex.org/I4210124779"]},{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]},{"id":"https://openalex.org/I4210124779","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80","country_code":"US","type":"government","lineage":["https://openalex.org/I4210124779"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Siddhita D. Mhatre","raw_affiliation_strings":["Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA; KBR, Houston, TX 77002, USA; COSMIAC Research Center, University of New Mexico, Albuquerque, NM 87131, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA; KBR, Houston, TX 77002, USA; COSMIAC Research Center, University of New Mexico, Albuquerque, NM 87131, USA","institution_ids":["https://openalex.org/I1280536761","https://openalex.org/I169521973","https://openalex.org/I4210124779"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040980656","display_name":"Rachel Gilbert","orcid":"https://orcid.org/0000-0003-1165-9655","observed_orcids":["https://orcid.org/0000-0003-1165-9655"]},"institutions":[{"id":"https://openalex.org/I1280536761","display_name":"Ames Research Center","ror":"https://ror.org/02acart68","country_code":"US","type":"facility","lineage":["https://openalex.org/I1280536761","https://openalex.org/I4210124779"]},{"id":"https://openalex.org/I1329765538","display_name":"Universities Space Research Association","ror":"https://ror.org/043pgqy52","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1329765538"]},{"id":"https://openalex.org/I4210124779","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80","country_code":"US","type":"government","lineage":["https://openalex.org/I4210124779"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rachel Gilbert","raw_affiliation_strings":["Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA; Universities Space Research Association, Columbia, MD 21046, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA; Universities Space Research Association, Columbia, MD 21046, USA","institution_ids":["https://openalex.org/I1280536761","https://openalex.org/I1329765538","https://openalex.org/I4210124779"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016289062","display_name":"Sharmila Bhattacharya","orcid":"https://orcid.org/0000-0002-1562-2692","observed_orcids":["https://orcid.org/0000-0002-1562-2692"]},"institutions":[{"id":"https://openalex.org/I1280536761","display_name":"Ames Research Center","ror":"https://ror.org/02acart68","country_code":"US","type":"facility","lineage":["https://openalex.org/I1280536761","https://openalex.org/I4210124779"]},{"id":"https://openalex.org/I4210124779","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80","country_code":"US","type":"government","lineage":["https://openalex.org/I4210124779"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sharmila Bhattacharya","raw_affiliation_strings":["Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA; Biological and Physical Sciences Division, NASA Headquarters, Washington DC 20024, USA. Electronic address: sharmila.bhattacharya@nasa.gov"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA; Biological and Physical Sciences Division, NASA Headquarters, Washington DC 20024, USA. Electronic address: sharmila.bhattacharya@nasa.gov","institution_ids":["https://openalex.org/I1280536761","https://openalex.org/I4210124779"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5016289062"],"corresponding_institution_ids":["https://openalex.org/I1280536761","https://openalex.org/I4210124779"],"apc_list":{"value":4720,"currency":"USD","value_usd":4720},"apc_paid":{"value":4720,"currency":"USD","value_usd":4720},"fwci":0.6051,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.5176565,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"142","issue":null,"first_page":"104880","last_page":"104880"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12788","display_name":"Space Science and Extraterrestrial Life","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/altered-gravity","display_name":"altered gravity","score":0.9430000185966492},{"id":"https://openalex.org/keywords/microgravity","display_name":"microgravity","score":0.8360000252723694},{"id":"https://openalex.org/keywords/spaceflight","display_name":"spaceflight","score":0.6449999809265137},{"id":"https://openalex.org/keywords/drosophila-melanogaster","display_name":"Drosophila melanogaster","score":0.9869999885559082},{"id":"https://openalex.org/keywords/gravitational-biology","display_name":"gravitational biology","score":0.6549999713897705},{"id":"https://openalex.org/keywords/long-duration-spaceflight","display_name":"long-duration spaceflight","score":0.7279999852180481},{"id":"https://openalex.org/keywords/astronaut-health","display_name":"astronaut health","score":0.5759999752044678},{"id":"https://openalex.org/keywords/neurobehavioral-effects","display_name":"neurobehavioral effects","score":0.7229999899864197},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.9610000252723694},{"id":"https://openalex.org/keywords/immune-response","display_name":"immune response","score":0.7599999904632568},{"id":"https://openalex.org/keywords/cardiovascular-system","display_name":"cardiovascular system","score":0.5979999899864197},{"id":"https://openalex.org/keywords/developmental-biology","display_name":"developmental biology","score":0.7670000195503235},{"id":"https://openalex.org/keywords/multi-omics","display_name":"multi-omics","score":0.9049999713897705},{"id":"https://openalex.org/keywords/circadian-lighting","display_name":"circadian lighting","score":0.6430000066757202},{"id":"https://openalex.org/keywords/ionizing-radiation","display_name":"ionizing radiation","score":0.8560000061988831}],"concepts":[{"id":"https://openalex.org/C103888896","wikidata":"https://www.wikidata.org/wiki/Q5916","display_name":"Spaceflight","level":2,"score":0.9420572519302368},{"id":"https://openalex.org/C2780104201","wikidata":"https://www.wikidata.org/wiki/Q130888","display_name":"Drosophila melanogaster","level":3,"score":0.7494075298309326},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5740564465522766},{"id":"https://openalex.org/C137858568","wikidata":"https://www.wikidata.org/wiki/Q7239","display_name":"Organism","level":2,"score":0.4779267907142639},{"id":"https://openalex.org/C534819032","wikidata":"https://www.wikidata.org/wiki/Q752783","display_name":"Human spaceflight","level":3,"score":0.43382686376571655},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.43332189321517944},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.41464561223983765},{"id":"https://openalex.org/C104060986","wikidata":"https://www.wikidata.org/wiki/Q180046","display_name":"Space exploration","level":2,"score":0.20961657166481018},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.18910104036331177},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13373130559921265},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.11539983749389648},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.08528661727905273},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006112","descriptor_name":"Gravitation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013026","descriptor_name":"Space Flight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018480","descriptor_name":"Astronauts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.neubiorev.2022.104880","doi":"https://doi.org/10.1016/j.neubiorev.2022.104880","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neubiorev.2022.104880","pdf_url":null,"source":{"id":"https://openalex.org/S170052170","display_name":"Neuroscience & Biobehavioral Reviews","issn_l":"0149-7634","issn":["0149-7634","1873-7528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience & Biobehavioral Reviews","raw_type":"journal-article"},{"id":"pmid:36126744","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36126744","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience and biobehavioral reviews","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.neubiorev.2022.104880","doi":"https://doi.org/10.1016/j.neubiorev.2022.104880","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neubiorev.2022.104880","pdf_url":null,"source":{"id":"https://openalex.org/S170052170","display_name":"Neuroscience & Biobehavioral Reviews","issn_l":"0149-7634","issn":["0149-7634","1873-7528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience & Biobehavioral Reviews","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1140474241","display_name":null,"funder_award_id":"NNX13AN38G","funder_id":"https://openalex.org/F4320333962","funder_display_name":"Science Mission Directorate"},{"id":"https://openalex.org/G580268649","display_name":null,"funder_award_id":"NNX15AB42G","funder_id":"https://openalex.org/F4320333962","funder_display_name":"Science Mission Directorate"}],"funders":[{"id":"https://openalex.org/F4320306101","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80"},{"id":"https://openalex.org/F4320333962","display_name":"Science Mission Directorate","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":104,"referenced_works":["https://openalex.org/W4319666","https://openalex.org/W109319306","https://openalex.org/W747538463","https://openalex.org/W980926729","https://openalex.org/W1488551842","https://openalex.org/W1567273140","https://openalex.org/W1592594564","https://openalex.org/W1625953294","https://openalex.org/W1756745003","https://openalex.org/W1799760597","https://openalex.org/W1944333689","https://openalex.org/W1974652211","https://openalex.org/W1975592927","https://openalex.org/W1980624509","https://openalex.org/W1982752795","https://openalex.org/W1986445184","https://openalex.org/W1987894596","https://openalex.org/W1992567157","https://openalex.org/W1992889302","https://openalex.org/W1998020630","https://openalex.org/W2000572318","https://openalex.org/W2000967656","https://openalex.org/W2003811750","https://openalex.org/W2004666307","https://openalex.org/W2005099705","https://openalex.org/W2006788765","https://openalex.org/W2009604662","https://openalex.org/W2012079462","https://openalex.org/W2027373024","https://openalex.org/W2039295111","https://openalex.org/W2041506510","https://openalex.org/W2045317481","https://openalex.org/W2053353041","https://openalex.org/W2053660330","https://openalex.org/W2057153376","https://openalex.org/W2057967798","https://openalex.org/W2060051326","https://openalex.org/W2061176599","https://openalex.org/W2062112950","https://openalex.org/W2065732852","https://openalex.org/W2068466141","https://openalex.org/W2072931298","https://openalex.org/W2074264546","https://openalex.org/W2080675956","https://openalex.org/W2082815622","https://openalex.org/W2083960671","https://openalex.org/W2083991002","https://openalex.org/W2093476254","https://openalex.org/W2100397154","https://openalex.org/W2102473269","https://openalex.org/W2102549002","https://openalex.org/W2102569027","https://openalex.org/W2106345203","https://openalex.org/W2115195542","https://openalex.org/W2117777628","https://openalex.org/W2127675271","https://openalex.org/W2129039672","https://openalex.org/W2131802378","https://openalex.org/W2132661305","https://openalex.org/W2141954707","https://openalex.org/W2145792907","https://openalex.org/W2156739718","https://openalex.org/W2165552650","https://openalex.org/W2304918283","https://openalex.org/W2311061917","https://openalex.org/W2325677894","https://openalex.org/W2329224694","https://openalex.org/W2419301763","https://openalex.org/W2471385389","https://openalex.org/W2474819442","https://openalex.org/W2501158984","https://openalex.org/W2519879438","https://openalex.org/W2523702009","https://openalex.org/W2552953928","https://openalex.org/W2556942022","https://openalex.org/W2564654127","https://openalex.org/W2594046448","https://openalex.org/W2594591188","https://openalex.org/W2600383617","https://openalex.org/W2605076090","https://openalex.org/W2605973827","https://openalex.org/W2615378728","https://openalex.org/W2744195203","https://openalex.org/W2755504498","https://openalex.org/W2783703909","https://openalex.org/W2794079760","https://openalex.org/W2802502574","https://openalex.org/W2808186163","https://openalex.org/W2898169239","https://openalex.org/W2919287201","https://openalex.org/W2939018266","https://openalex.org/W2966710019","https://openalex.org/W2967582487","https://openalex.org/W2998658733","https://openalex.org/W3004983543","https://openalex.org/W3094637207","https://openalex.org/W3108839190","https://openalex.org/W3109264404","https://openalex.org/W4211191954","https://openalex.org/W4225369327","https://openalex.org/W4243118145","https://openalex.org/W4294771200","https://openalex.org/W4388251269","https://openalex.org/W7075996225"],"related_works":["https://openalex.org/W7065764656","https://openalex.org/W7115723637","https://openalex.org/W3175683606","https://openalex.org/W3176688395","https://openalex.org/W4416265885","https://openalex.org/W4307395132","https://openalex.org/W4294771200","https://openalex.org/W4405559224","https://openalex.org/W7202251566","https://openalex.org/W2580458060"],"abstract_inverted_index":{"NASA":[0],"is":[1,30],"planning":[2],"to":[3,15,37,55,82],"resume":[4],"human-crewed":[5],"lunar":[6],"missions":[7],"and":[8,48,105,110],"lay":[9],"the":[10,21,64,69,79],"foundation":[11],"for":[12],"human":[13,28],"exploration":[14],"Mars.":[16],"However,":[17],"our":[18],"knowledge":[19],"of":[20,24,78],"overall":[22],"effects":[23],"long-duration":[25],"spaceflight":[26,90],"on":[27],"physiology":[29],"limited.":[31],"During":[32],"spaceflight,":[33],"astronauts":[34],"are":[35],"exposed":[36],"multiple":[38],"risk":[39],"factors,":[40],"including":[41,99],"gravitational":[42,72],"changes,":[43],"ionizing":[44],"radiation,":[45],"physiological":[46],"stress,":[47],"altered":[49],"circadian":[50],"lighting.":[51],"These":[52],"factors":[53],"contribute":[54],"pathophysiological":[56],"responses":[57],"that":[58],"target":[59],"different":[60],"organ":[61],"systems":[62],"in":[63,71,115],"body.":[65],"This":[66],"review":[67],"discusses":[68],"advancements":[70],"biology":[73],"using":[74],"Drosophila":[75],"melanogaster,":[76],"one":[77],"first":[80],"organisms":[81],"be":[83],"launched":[84],"into":[85],"space.":[86],"As":[87],"a":[88],"well-established":[89],"model":[91],"organism,":[92],"fruit":[93],"flies":[94],"have":[95],"yielded":[96],"significant":[97],"information,":[98],"neurobehavioral,":[100],"aging,":[101],"immune,":[102],"cardiovascular,":[103],"developmental,":[104],"multi-omics":[106],"changes":[107],"across":[108],"tissues":[109],"developmental":[111],"stages,":[112],"as":[113],"detailed":[114],"this":[116],"review.":[117]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2022-09-17T00:00:00"}