{"id":"https://openalex.org/W4295909083","doi":"https://doi.org/10.1172/jci.insight.161438","title":"Keratinocyte-derived cytokine TSLP promotes growth and metastasis of melanoma by regulating the tumor-associated immune microenvironment","display_name":"Keratinocyte-derived cytokine TSLP promotes growth and metastasis of melanoma by regulating the tumor-associated immune microenvironment","publication_year":2022,"publication_date":"2022-09-15","ids":{"openalex":"https://openalex.org/W4295909083","doi":"https://doi.org/10.1172/jci.insight.161438","pmid":"https://pubmed.ncbi.nlm.nih.gov/36107619","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9675576"},"language":"en","primary_location":{"id":"doi:10.1172/jci.insight.161438","doi":"https://doi.org/10.1172/jci.insight.161438","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci.insight.161438","pdf_url":"http://insight.jci.org/articles/view/161438/files/pdf","source":{"id":"https://openalex.org/S2764964142","display_name":"JCI Insight","issn_l":"2379-3708","issn":["2379-3708"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCI Insight","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://insight.jci.org/articles/view/161438/files/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070711038","display_name":"Wenjin Yao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Wenjin Yao","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039840613","display_name":"Beatriz German","orcid":"https://orcid.org/0009-0004-5105-4583","observed_orcids":["https://orcid.org/0009-0004-5105-4583","https://orcid.org/0000-0001-8561-5765"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Beatriz German","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002690057","display_name":"Dounia Chraa","orcid":"https://orcid.org/0000-0002-6868-4352","observed_orcids":["https://orcid.org/0000-0002-6868-4352"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I4210144608","display_name":"Centre de Recherche en Canc\u00e9rologie de Marseille","ror":"https://ror.org/0494jpz02","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210096427","https://openalex.org/I4210144608","https://openalex.org/I4210150365"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Dounia Chraa","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","CRCM - Centre de Recherche en Canc\u00e9rologie de Marseille (27 bd Le\u00ef Roure, BP 300059\r\n13273 Marseille Cedex 09 - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"CRCM - Centre de Recherche en Canc\u00e9rologie de Marseille (27 bd Le\u00ef Roure, BP 300059\r\n13273 Marseille Cedex 09 - France)","institution_ids":["https://openalex.org/I4210144608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091365998","display_name":"Antoine Braud","orcid":"https://orcid.org/0000-0001-5207-3357","observed_orcids":["https://orcid.org/0000-0001-5207-3357"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I4210145324","display_name":"H\u00f4pitaux Universitaires de Strasbourg","ror":"https://ror.org/04bckew43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210145324"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Antoine Braud","raw_affiliation_strings":["Dermatology Clinic, Strasbourg University Hospital, Strasbourg, France","Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","CHU Strasbourg - Centre Hospitalier Universitaire [Strasbourg] (France)","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dermatology Clinic, Strasbourg University Hospital, Strasbourg, France","institution_ids":["https://openalex.org/I4210145324"]},{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"CHU Strasbourg - Centre Hospitalier Universitaire [Strasbourg] (France)","institution_ids":["https://openalex.org/I4210145324"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060154132","display_name":"C\u00e9cile Hugel","orcid":"https://orcid.org/0000-0002-5472-0906","observed_orcids":["https://orcid.org/0000-0002-5472-0906"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Cecile Hugel","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":"https://orcid.org/0000-0002-5472-0906","affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042498713","display_name":"Pierre Meyer","orcid":"https://orcid.org/0000-0001-9547-7976","observed_orcids":["https://orcid.org/0000-0001-9547-7976"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pierre Meyer","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":"https://orcid.org/0000-0001-9547-7976","affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076592760","display_name":"Guillaume Davidson","orcid":"https://orcid.org/0000-0001-9272-3924","observed_orcids":["https://orcid.org/0000-0001-9272-3924"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Guillaume Davidson","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":"https://orcid.org/0000-0001-9272-3924","affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058611582","display_name":"Patrick Laurette","orcid":"https://orcid.org/0000-0002-8941-612X","observed_orcids":["https://orcid.org/0000-0002-8941-612X"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Patrick Laurette","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":"https://orcid.org/0000-0002-8941-612X","affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008025415","display_name":"Gabrielle Mengus","orcid":"https://orcid.org/0000-0002-2844-1778","observed_orcids":["https://orcid.org/0000-0002-2844-1778"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Gabrielle Mengus","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001775231","display_name":"Eric Flatter","orcid":"https://orcid.org/0000-0001-6812-5887","observed_orcids":["https://orcid.org/0000-0001-6812-5887"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Eric Flatter","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023871472","display_name":"Pierre Marschall","orcid":"https://orcid.org/0000-0001-6718-149X","observed_orcids":["https://orcid.org/0000-0001-6718-149X"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pierre Marschall","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075975859","display_name":"Justine Segaud","orcid":"https://orcid.org/0000-0003-4687-7046","observed_orcids":["https://orcid.org/0000-0003-4687-7046"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Justine Segaud","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":"https://orcid.org/0000-0003-4687-7046","affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072294951","display_name":"Marine Guivarch","orcid":"https://orcid.org/0000-0002-7051-9911","observed_orcids":["https://orcid.org/0000-0002-7051-9911"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marine Guivarch","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":"https://orcid.org/0000-0002-7051-9911","affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041069908","display_name":"Pierre Hener","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pierre Hener","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056396727","display_name":"Marie\u2010Christine Birling","orcid":"https://orcid.org/0000-0002-3372-8108","observed_orcids":["https://orcid.org/0000-0002-3372-8108"]},"institutions":[{"id":"https://openalex.org/I4210126578","display_name":"Ph\u00e9notypage et ing\u00e9nierie pr\u00e9cliniques des syst\u00e8mes d\u2019organismes mod\u00e8les","ror":"https://ror.org/03cjqqq10","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210126578"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie-Christine Birling","raw_affiliation_strings":["Institut Clinique de la Souris (ICS), Illkirch, France","ICS - Institut Clinique de la Souris (G\u00e9nopole de Strasbourg 67404 Illkirch Cedex - France)"],"raw_orcid":"https://orcid.org/0000-0002-3372-8108","affiliations":[{"raw_affiliation_string":"Institut Clinique de la Souris (ICS), Illkirch, France","institution_ids":["https://openalex.org/I4210126578"]},{"raw_affiliation_string":"ICS - Institut Clinique de la Souris (G\u00e9nopole de Strasbourg 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210126578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017830680","display_name":"Dan M. Lipsker","orcid":"https://orcid.org/0000-0003-4675-0336","observed_orcids":["https://orcid.org/0000-0003-4675-0336"]},"institutions":[{"id":"https://openalex.org/I4210145324","display_name":"H\u00f4pitaux Universitaires de Strasbourg","ror":"https://ror.org/04bckew43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210145324"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Dan Lipsker","raw_affiliation_strings":["Dermatology Clinic, Strasbourg University Hospital, Strasbourg, France","CHU Strasbourg - Centre Hospitalier Universitaire [Strasbourg] (France)"],"raw_orcid":"https://orcid.org/0000-0003-4675-0336","affiliations":[{"raw_affiliation_string":"Dermatology Clinic, Strasbourg University Hospital, Strasbourg, France","institution_ids":["https://openalex.org/I4210145324"]},{"raw_affiliation_string":"CHU Strasbourg - Centre Hospitalier Universitaire [Strasbourg] (France)","institution_ids":["https://openalex.org/I4210145324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037577234","display_name":"Irwin Davidson","orcid":"https://orcid.org/0000-0001-5533-1171","observed_orcids":["https://orcid.org/0000-0001-5533-1171"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Irwin Davidson","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":"https://orcid.org/0000-0001-5533-1171","affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100331935","display_name":"Mei Li","orcid":"https://orcid.org/0000-0003-4225-6699","observed_orcids":["https://orcid.org/0000-0003-4225-6699"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Mei Li","raw_affiliation_strings":["Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)"],"raw_orcid":"https://orcid.org/0000-0003-4225-6699","affiliations":[{"raw_affiliation_string":"Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (IGBMC), CNRS UMR 7104, Inserm U 1258, University of Strasbourg, Illkirch, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"]},{"raw_affiliation_string":"IGBMC - Institut de G\u00e9n\u00e9tique et de Biologie Mol\u00e9culaire et Cellulaire (Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 Illkirch Cedex - France)","institution_ids":["https://openalex.org/I4210086872"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5100331935"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I68947357"],"apc_list":{"value":4100,"currency":"USD","value_usd":4100},"apc_paid":{"value":4100,"currency":"USD","value_usd":4100},"fwci":2.2142,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.90130995,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"7","issue":"21","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.8417999744415283,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.8417999744415283,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management","score":0.04800000041723251,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.046300001442432404,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thymic-stromal-lymphopoietin","display_name":"thymic stromal lymphopoietin","score":0.984000027179718},{"id":"https://openalex.org/keywords/melanoma","display_name":"melanoma","score":0.75},{"id":"https://openalex.org/keywords/cutaneous-melanoma","display_name":"cutaneous melanoma","score":0.8299999833106995},{"id":"https://openalex.org/keywords/keratinocytes","display_name":"keratinocytes","score":0.8450000286102295},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.8320000171661377},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.8320000171661377},{"id":"https://openalex.org/keywords/regulatory-t-cells","display_name":"regulatory T cells","score":0.7979999780654907},{"id":"https://openalex.org/keywords/gata3","display_name":"GATA3","score":0.8859999775886536},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.9150000214576721},{"id":"https://openalex.org/keywords/tslp-receptor","display_name":"TSLP receptor","score":0.7910000085830688},{"id":"https://openalex.org/keywords/immune-evasion","display_name":"immune evasion","score":0.6769999861717224},{"id":"https://openalex.org/keywords/cd8-t-cell-suppression","display_name":"CD8+ T cell suppression","score":0.8460000157356262},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.7170000076293945}],"concepts":[{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.758845329284668},{"id":"https://openalex.org/C2778070265","wikidata":"https://www.wikidata.org/wiki/Q18048067","display_name":"Thymic stromal lymphopoietin","level":3,"score":0.7075422406196594},{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.696557343006134},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6440160870552063},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6196353435516357},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5374062657356262},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.5257566571235657},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5074517130851746},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.4856661558151245},{"id":"https://openalex.org/C102037460","wikidata":"https://www.wikidata.org/wiki/Q18025464","display_name":"GATA3","level":4,"score":0.4279231131076813},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.410400390625},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3922811448574066},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2687622308731079},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07136255502700806},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.06886780261993408},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000094632","descriptor_name":"Thymic Stromal Lymphopoietin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000096142","descriptor_name":"Cutaneous Malignant Melanoma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008545","descriptor_name":"Melanoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008545","descriptor_name":"Melanoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015603","descriptor_name":"Keratinocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1172/jci.insight.161438","doi":"https://doi.org/10.1172/jci.insight.161438","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci.insight.161438","pdf_url":"http://insight.jci.org/articles/view/161438/files/pdf","source":{"id":"https://openalex.org/S2764964142","display_name":"JCI Insight","issn_l":"2379-3708","issn":["2379-3708"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCI Insight","raw_type":"journal-article"},{"id":"pmid:36107619","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36107619","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCI insight","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9675576","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9675576/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCI Insight","raw_type":"Text"},{"id":"pmh:oai:HAL:hal-03808723v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-03808723v1/document","pdf_url":null,"source":{"id":"https://openalex.org/S4406922393","display_name":"HAL AMU","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"JCI Insight, 2022, ⟨10.1172/jci.insight.161438⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:806463a8c74345f79b39cc61de47f3e4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/806463a8c74345f79b39cc61de47f3e4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"JCI Insight, Vol 7, Iss 21 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1172/jci.insight.161438","doi":"https://doi.org/10.1172/jci.insight.161438","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci.insight.161438","pdf_url":"http://insight.jci.org/articles/view/161438/files/pdf","source":{"id":"https://openalex.org/S2764964142","display_name":"JCI Insight","issn_l":"2379-3708","issn":["2379-3708"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCI Insight","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2184907896","display_name":"Par-del\u00e0 les fronti\u00e8res, l'Universit\u00e9 de Strasbourg","funder_award_id":"ANR-10-IDEX-0002","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G2659019386","display_name":null,"funder_award_id":"ANR-17-EURE-","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G2694206344","display_name":null,"funder_award_id":"ANR-10-IDEX- 0002","funder_id":"https://openalex.org/F4320322147","funder_display_name":"Universit\u00e9 de Strasbourg"},{"id":"https://openalex.org/G2883645776","display_name":"Fa\u00e7onner les talents en formation et en recherche \u00e0 l'Universit\u00e9 de Strasbourg","funder_award_id":"ANR-20-SFRI-0012","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G2980570810","display_name":null,"funder_award_id":"ANR-17-EURE-0023","funder_id":"https://openalex.org/F4320322147","funder_display_name":"Universit\u00e9 de Strasbourg"},{"id":"https://openalex.org/G3010527862","display_name":null,"funder_award_id":"ANR\u201019","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G3357951378","display_name":null,"funder_award_id":"ANR 10 IDEX 0002","funder_id":"https://openalex.org/F4320320893","funder_display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale"},{"id":"https://openalex.org/G3730343","display_name":null,"funder_award_id":"ANR-17-EURE-0023","funder_id":"https://openalex.org/F4320320893","funder_display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale"},{"id":"https://openalex.org/G4523961199","display_name":"Integrative Molecular and Cellular Biology","funder_award_id":"ANR-17-EURE-0023","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G471331628","display_name":null,"funder_award_id":"ANR-10-IDEX","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G4779185514","display_name":null,"funder_award_id":"ITI 2021 2028","funder_id":"https://openalex.org/F4320322147","funder_display_name":"Universit\u00e9 de Strasbourg"},{"id":"https://openalex.org/G5068882015","display_name":"Mathematics and Interactions in Toulouse","funder_award_id":"ANR-18-EURE-0023","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G5424012126","display_name":"IL-3 axis as a target to inhibit basophils in inflammatory conditions","funder_award_id":"ANR-19-CE17-0021","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G6136357505","display_name":null,"funder_award_id":"2021-2028","funder_id":"https://openalex.org/F4320322892","funder_display_name":"Centre National de la Recherche Scientifique"},{"id":"https://openalex.org/G6803667113","display_name":null,"funder_award_id":"ANR-17","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G7240651115","display_name":null,"funder_award_id":"ANR-10","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G913179920","display_name":"Development of a novel biotherapy targeting inflammatory pathways in Netherton syndrome","funder_award_id":"ANR-19-CE17-0017","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320320893","display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","ror":"https://ror.org/02vjkv261"},{"id":"https://openalex.org/F4320322147","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24"},{"id":"https://openalex.org/F4320322361","display_name":"Fondation ARC pour la Recherche sur le Cancer","ror":"https://ror.org/0489qz649"},{"id":"https://openalex.org/F4320322363","display_name":"Ligue Contre le Cancer","ror":"https://ror.org/00rkrv905"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"},{"id":"https://openalex.org/F4320323807","display_name":"Institut National Du Cancer","ror":"https://ror.org/03m8vkq32"},{"id":"https://openalex.org/F4320331313","display_name":"Laboratoire d'Excellence INRT","ror":null},{"id":"https://openalex.org/F4320338065","display_name":"Institute of Genetics","ror":"https://ror.org/03gwhmn95"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4295909083.pdf","grobid_xml":"https://content.openalex.org/works/W4295909083.grobid-xml"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W1488736033","https://openalex.org/W1545137049","https://openalex.org/W1969030103","https://openalex.org/W1970195561","https://openalex.org/W1971896241","https://openalex.org/W1975438745","https://openalex.org/W1983180761","https://openalex.org/W1985965203","https://openalex.org/W1987896433","https://openalex.org/W1988038318","https://openalex.org/W2019544036","https://openalex.org/W2029848679","https://openalex.org/W2037033919","https://openalex.org/W2046318425","https://openalex.org/W2052071954","https://openalex.org/W2067919290","https://openalex.org/W2070829001","https://openalex.org/W2078724064","https://openalex.org/W2096322385","https://openalex.org/W2109909774","https://openalex.org/W2111709938","https://openalex.org/W2114675972","https://openalex.org/W2123105952","https://openalex.org/W2126973239","https://openalex.org/W2134471382","https://openalex.org/W2135790224","https://openalex.org/W2140299259","https://openalex.org/W2147582494","https://openalex.org/W2149336558","https://openalex.org/W2155127143","https://openalex.org/W2161275429","https://openalex.org/W2172023354","https://openalex.org/W2178170089","https://openalex.org/W2189381691","https://openalex.org/W2261557117","https://openalex.org/W2328039719","https://openalex.org/W2345395916","https://openalex.org/W2419439766","https://openalex.org/W2550291749","https://openalex.org/W2552653135","https://openalex.org/W2560367415","https://openalex.org/W2579992807","https://openalex.org/W2606447252","https://openalex.org/W2736312236","https://openalex.org/W2736723060","https://openalex.org/W2799874579","https://openalex.org/W2884462708","https://openalex.org/W2897925268","https://openalex.org/W2898830231","https://openalex.org/W2899145148","https://openalex.org/W2907549567","https://openalex.org/W2921822469","https://openalex.org/W2928824653","https://openalex.org/W2940894470","https://openalex.org/W2944426093","https://openalex.org/W2945947513","https://openalex.org/W2946348245","https://openalex.org/W2952257329","https://openalex.org/W2977406305","https://openalex.org/W2990642475","https://openalex.org/W3002455262","https://openalex.org/W3003124479","https://openalex.org/W3085191016","https://openalex.org/W3092398820","https://openalex.org/W3093152284","https://openalex.org/W3158284947","https://openalex.org/W4211033466","https://openalex.org/W4280584975"],"related_works":["https://openalex.org/W7163380552","https://openalex.org/W4416586166","https://openalex.org/W7163721010","https://openalex.org/W4313381287","https://openalex.org/W7135550257","https://openalex.org/W7101117480","https://openalex.org/W2908784041","https://openalex.org/W166228974","https://openalex.org/W7160830969","https://openalex.org/W4313351389"],"abstract_inverted_index":{"Malignant":[0],"melanoma":[1,24,60,71,86,105,115,176],"is":[2,35,56,99],"a":[3,83,94,140,153,189],"major":[4,17],"public":[5],"health":[6],"issue":[7],"displaying":[8],"frequent":[9],"resistance":[10],"to":[11,113,130],"targeted":[12],"therapy":[13],"and":[14,29,33,64,72,89,107,117,149,151,162],"immunotherapy.":[15],"A":[16],"challenge":[18],"lies":[19],"in":[20,61,92,135,174,187,193],"better":[21],"understanding":[22],"how":[23,30],"cells":[25,91,106,112],"evade":[26],"immune":[27,90,111,191],"elimination":[28],"tumor":[31,39,73],"growth":[32],"metastasis":[34],"facilitated":[36],"by":[37,53,58,101],"the":[38,47,183],"microenvironment.":[40,96],"Here,":[41],"we":[42,81,120],"show":[43,121],"that":[44,122],"expression":[45],"of":[46,70,168,185],"cytokine":[48],"thymic":[49],"stromal":[50],"lymphopoietin":[51],"(TSLP)":[52],"epidermal":[54],"keratinocytes":[55],"induced":[57,100],"cutaneous":[59,194],"both":[62],"mice":[63],"humans.":[65],"Using":[66],"genetically":[67],"engineered":[68],"models":[69],"cell":[74,160],"grafting":[75],"combined":[76],"with":[77],"TSLP-KO":[78],"or":[79],"overexpression,":[80],"defined":[82],"crosstalk":[84],"between":[85],"cells,":[87],"keratinocytes,":[88],"establishing":[93],"tumor-promoting":[95],"Keratinocyte-derived":[97],"TSLP":[98,123,126,186],"signals":[102,124],"derived":[103],"from":[104],"subsequently":[108],"acts":[109],"via":[110],"promote":[114],"progression":[116],"metastasis.":[118],"Furthermore,":[119],"through":[125],"receptor-expressing":[127],"(TSLPR-expressing)":[128],"DCs":[129],"play":[131],"an":[132],"unrecognized":[133],"role":[134,184],"promoting":[136],"GATA3+":[137],"Tregs":[138,170],"expressing":[139],"gene":[141],"signature":[142],"including":[143],"ST2,":[144],"CCR8,":[145],"ICOS,":[146],"PD-1,":[147],"CTLA-4,":[148],"OX40":[150],"exhibiting":[152],"potent":[154],"suppressive":[155],"activity":[156],"on":[157],"CD8+":[158],"T":[159],"proliferation":[161],"IFN-\u03b3":[163],"production.":[164],"An":[165],"analogous":[166],"population":[167],"GATA3-expressing":[169],"was":[171],"also":[172],"identified":[173],"human":[175],"tumors.":[177],"Our":[178],"study":[179],"provides":[180],"insights":[181],"into":[182],"programming":[188],"protumoral":[190],"microenvironment":[192],"melanoma.":[195]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":7}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2022-09-16T00:00:00"}