{"id":"https://openalex.org/W4294671773","doi":"https://doi.org/10.1002/jso.27084","title":"Short and long\u2010term outcomes of prophylactic total gastrectomy in 54 consecutive individuals with germline pathogenic mutations in the CDH1 gene","display_name":"Short and long\u2010term outcomes of prophylactic total gastrectomy in 54 consecutive individuals with germline pathogenic mutations in the CDH1 gene","publication_year":2022,"publication_date":"2022-09-05","ids":{"openalex":"https://openalex.org/W4294671773","doi":"https://doi.org/10.1002/jso.27084","pmid":"https://pubmed.ncbi.nlm.nih.gov/36063148","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9649870"},"language":"en","primary_location":{"id":"doi:10.1002/jso.27084","doi":"https://doi.org/10.1002/jso.27084","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jso.27084","pdf_url":null,"source":{"id":"https://openalex.org/S13860802","display_name":"Journal of Surgical Oncology","issn_l":"0022-4790","issn":["0022-4790","1096-9098"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9649870","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069571172","display_name":"Mason D. Stillman","orcid":"https://orcid.org/0000-0003-1058-433X","observed_orcids":["https://orcid.org/0000-0003-1058-433X"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mason D. Stillman","raw_affiliation_strings":["Division of Surgical Oncology, Department of Surgery, Columbia University Irving Medical Center, New York City, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical Oncology, Department of Surgery, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068828202","display_name":"Nicole Kusche","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole Kusche","raw_affiliation_strings":["Division of Surgical Oncology, Department of Surgery, Columbia University Irving Medical Center, New York City, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical Oncology, Department of Surgery, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060983999","display_name":"Sabrina Toledano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sabrina Toledano","raw_affiliation_strings":["Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042069476","display_name":"Kimberly J. Hilfrank","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly J. Hilfrank","raw_affiliation_strings":["Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079480597","display_name":"Changhwan Yoon","orcid":"https://orcid.org/0000-0002-8420-9818","observed_orcids":["https://orcid.org/0000-0002-8420-9818"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Changhwan Yoon","raw_affiliation_strings":["Division of Surgical Oncology, Department of Surgery, Columbia University Irving Medical Center, New York City, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical Oncology, Department of Surgery, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059326174","display_name":"Joel  T. Gabre","orcid":"https://orcid.org/0000-0002-5347-3341","observed_orcids":["https://orcid.org/0000-0002-5347-3341"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4390039230","display_name":"Herbert Irving Comprehensive Cancer Center","ror":"https://ror.org/051kc1939","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039230"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joel T. Gabre","raw_affiliation_strings":["Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA","Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York City, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I4390039230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022635801","display_name":"Sheila D. Rustgi","orcid":"https://orcid.org/0000-0002-1889-1652","observed_orcids":["https://orcid.org/0000-0002-1889-1652"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sheila D. Rustgi","raw_affiliation_strings":["Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055200350","display_name":"Chin Hur","orcid":"https://orcid.org/0000-0002-2819-7576","observed_orcids":["https://orcid.org/0000-0002-2819-7576"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4390039230","display_name":"Herbert Irving Comprehensive Cancer Center","ror":"https://ror.org/051kc1939","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039230"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chin Hur","raw_affiliation_strings":["Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA","Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York City, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I4390039230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034561048","display_name":"Fay Kastrinos","orcid":"https://orcid.org/0000-0003-2518-0100","observed_orcids":["https://orcid.org/0000-0003-2518-0100"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4390039230","display_name":"Herbert Irving Comprehensive Cancer Center","ror":"https://ror.org/051kc1939","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039230"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fay Kastrinos","raw_affiliation_strings":["Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA","Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York City, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I4390039230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045541621","display_name":"Sandra W. Ryeom","orcid":"https://orcid.org/0000-0002-9869-4455","observed_orcids":["https://orcid.org/0000-0002-9869-4455"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4390039230","display_name":"Herbert Irving Comprehensive Cancer Center","ror":"https://ror.org/051kc1939","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039230"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sandra W. Ryeom","raw_affiliation_strings":["Division of Surgical Oncology, Department of Surgery, Columbia University Irving Medical Center, New York City, New York, USA","Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York City, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical Oncology, Department of Surgery, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I4390039230"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027745721","display_name":"Sam S. Yoon","orcid":"https://orcid.org/0000-0002-5033-6501","observed_orcids":["https://orcid.org/0000-0002-5033-6501"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I4390039230","display_name":"Herbert Irving Comprehensive Cancer Center","ror":"https://ror.org/051kc1939","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039230"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sam S. Yoon","raw_affiliation_strings":["Division of Surgical Oncology, Department of Surgery, Columbia University Irving Medical Center, New York City, New York, USA","Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York City, New York, USA"],"raw_orcid":"https://orcid.org/0000-0002-5033-6501","affiliations":[{"raw_affiliation_string":"Division of Surgical Oncology, Department of Surgery, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643"]},{"raw_affiliation_string":"Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York City, New York, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I4390039230"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5027745721"],"corresponding_institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I4390039230"],"apc_list":{"value":4300,"currency":"USD","value_usd":4300},"apc_paid":null,"fwci":1.9137,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.87165609,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"126","issue":"8","first_page":"1413","last_page":"1422"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11485","display_name":"Gastrointestinal Tumor Research and Treatment","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cdh1-mutation","display_name":"CDH1 mutation","score":0.7229999899864197},{"id":"https://openalex.org/keywords/hereditary-diffuse-gastric-cancer","display_name":"hereditary diffuse gastric cancer","score":0.9610000252723694},{"id":"https://openalex.org/keywords/prophylactic-total-gastrectomy","display_name":"prophylactic total gastrectomy","score":0.9679999947547913},{"id":"https://openalex.org/keywords/germline-pathogenic-variants","display_name":"germline pathogenic variants","score":0.7039999961853027},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.6840000152587891},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.8019999861717224},{"id":"https://openalex.org/keywords/weight-loss","display_name":"weight loss","score":0.7620000243186951},{"id":"https://openalex.org/keywords/gastric-mucosa-pathology","display_name":"gastric mucosa pathology","score":0.5260000228881836},{"id":"https://openalex.org/keywords/surveillance-endoscopy","display_name":"endoscopic surveillance","score":0.5609999895095825},{"id":"https://openalex.org/keywords/lynch-syndrome","display_name":"Lynch syndrome","score":0.4169999957084656}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9616925716400146},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5323299169540405},{"id":"https://openalex.org/C13514818","wikidata":"https://www.wikidata.org/wiki/Q5552256","display_name":"Germline mutation","level":4,"score":0.5104414224624634},{"id":"https://openalex.org/C2780470880","wikidata":"https://www.wikidata.org/wiki/Q827390","display_name":"Gastrectomy","level":3,"score":0.4859400987625122},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.457788348197937},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.44721367955207825},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39220476150512695},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.1750580072402954},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005743","descriptor_name":"Gastrectomy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005854","descriptor_name":"Germ Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D015703","descriptor_name":"Antigens, CD","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015820","descriptor_name":"Cadherins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018095","descriptor_name":"Germ-Line Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/jso.27084","doi":"https://doi.org/10.1002/jso.27084","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jso.27084","pdf_url":null,"source":{"id":"https://openalex.org/S13860802","display_name":"Journal of Surgical Oncology","issn_l":"0022-4790","issn":["0022-4790","1096-9098"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Oncology","raw_type":"journal-article"},{"id":"pmid:36063148","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36063148","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of surgical oncology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9649870","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9649870","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Surg Oncol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:9649870","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9649870","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Surg Oncol","raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G7687684229","display_name":"HIF-1alpha and FBP2 in sarcoma metabolism, progression, and metastasis","funder_award_id":"R01CA158301","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000916142","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA013696","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000920410","display_name":"The Columbia University Digestive and Liver Disease Research Center","funder_award_id":"P30DK132710","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320311125","display_name":"DeGregorio Family Foundation","ror":"https://ror.org/051yr1559"},{"id":"https://openalex.org/F4320332898","display_name":"Stand Up To Cancer","ror":"https://ror.org/01dmpb598"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1526524891","https://openalex.org/W1651458958","https://openalex.org/W1827130897","https://openalex.org/W1974970070","https://openalex.org/W1979488027","https://openalex.org/W1979505082","https://openalex.org/W1995906576","https://openalex.org/W2032314108","https://openalex.org/W2055525927","https://openalex.org/W2055850634","https://openalex.org/W2060902004","https://openalex.org/W2081256791","https://openalex.org/W2082171113","https://openalex.org/W2103172754","https://openalex.org/W2105956673","https://openalex.org/W2117264602","https://openalex.org/W2120370521","https://openalex.org/W2122236541","https://openalex.org/W2131042294","https://openalex.org/W2144126050","https://openalex.org/W2152243442","https://openalex.org/W2154175915","https://openalex.org/W2160828835","https://openalex.org/W2316411948","https://openalex.org/W2338576041","https://openalex.org/W2396271593","https://openalex.org/W2418941039","https://openalex.org/W2473854056","https://openalex.org/W2550757515","https://openalex.org/W2609752905","https://openalex.org/W2724907058","https://openalex.org/W2793427543","https://openalex.org/W2886652598","https://openalex.org/W2902383515","https://openalex.org/W2902851512","https://openalex.org/W2909363710","https://openalex.org/W2953590029","https://openalex.org/W2955200305","https://openalex.org/W2959623928","https://openalex.org/W2982479752","https://openalex.org/W2991442809","https://openalex.org/W3005565316","https://openalex.org/W3047025380","https://openalex.org/W3090494833","https://openalex.org/W3119540840","https://openalex.org/W3128646645","https://openalex.org/W3128647485","https://openalex.org/W3207864114","https://openalex.org/W4250948394","https://openalex.org/W4415323928"],"related_works":["https://openalex.org/W2144126050","https://openalex.org/W4388792271","https://openalex.org/W4402462239","https://openalex.org/W7114991225","https://openalex.org/W4311709203","https://openalex.org/W2984517888","https://openalex.org/W2414934329","https://openalex.org/W2887317694","https://openalex.org/W2537865442","https://openalex.org/W3168268703"],"abstract_inverted_index":{"BACKGROUND:":[0],"Germline":[1],"mutation":[2,20],"of":[3,45,96,109,112,127,152],"CDH1":[4,19],"is":[5],"rare":[6],"and":[7,54,62,79,84,132,172],"leads":[8],"to":[9],"hereditary":[10],"diffuse":[11],"gastric":[12,104],"cancer":[13],"(DGC).":[14],"METHODS:":[15],"Patients":[16],"(pts)":[17],"with":[18,41,120,167,193],"who":[21],"underwent":[22,50],"multidisciplinary":[23],"counseling":[24],"followed":[25],"by":[26,32],"open":[27],"prophylactic":[28],"total":[29],"gastrectomy":[30],"(PTG)":[31],"a":[33,42,107,125],"single":[34],"surgeon":[35],"were":[36,72,89],"reviewed.":[37],"RESULTS:":[38],"Fifty-four":[39],"pts":[40,100,119,134],"median":[43,63,108,126,155],"age":[44],"41":[46],"years":[47],"(16-70":[48],"years)":[49,151],"PTG":[51,179,184],"between":[52],"2006":[53],"2021.":[55],"Median":[56,140],"operative":[57],"time":[58],"was":[59,66,144,158],"161":[60],"min,":[61],"hospital":[64],"stay":[65],"7":[67],"days":[68],"(range":[69,114,130],"6-12).":[70],"There":[71,88],"5":[73],"complications":[74,81],"(9.2%)":[75],"within":[76],"30":[77],"days,":[78],"two":[80,133],"(pulmonary":[82],"embolism":[83],"pancreatitis)":[85],"required":[86],"readmission.":[87],"no":[90,137],"anastomotic":[91],"leaks.":[92],"The":[93,116],"pathologic":[94],"analysis":[95,123],"the":[97,102,162],"first":[98],"10":[99],"included":[101],"entire":[103],"mucosa,":[105],"revealing":[106],"15":[110],"foci":[111,129,138],"DGC":[113],"5-136).":[115],"subsequent":[117],"44":[118],"more":[121],"limited":[122],"had":[124,136,164],"2":[128],"0-5),":[131],"(3.7%)":[135],"identified.":[139],"maximum":[141],"weight":[142],"loss":[143],"19%.":[145],"In":[146],"long-term":[147],"follow-up":[148],"(median":[149],"4.6":[150],"20":[153],"pts,":[154],"global":[156],"QOL":[157,196],"2.0":[159],"(very":[160],"good),":[161],"majority":[163],"persistent":[165],"difficulty":[166],"certain":[168],"foods":[169],"or":[170],"liquids,":[171],"all":[173],"stated":[174],"they":[175],"would":[176],"again":[177],"elect":[178],"over":[180],"surveillance":[181],"endoscopy.":[182],"CONCLUSIONS:":[183],"can":[185],"be":[186],"performed":[187],"safely":[188],"at":[189],"high-volume":[190],"referral":[191],"centers":[192],"very":[194],"good":[195],"but":[197],"nutritional":[198],"sequelae":[199],"persist.":[200]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-09-06T00:00:00"}
