{"id":"https://openalex.org/W4294408705","doi":"https://doi.org/10.2174/1570159x20666220901154034","title":"Hunting for Genes Underlying Emotionality in the Laboratory Rat: Maps, Tools and Traps","display_name":"Hunting for Genes Underlying Emotionality in the Laboratory Rat: Maps, Tools and Traps","publication_year":2022,"publication_date":"2022-09-03","ids":{"openalex":"https://openalex.org/W4294408705","doi":"https://doi.org/10.2174/1570159x20666220901154034","pmid":"https://pubmed.ncbi.nlm.nih.gov/36056863","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10514530"},"language":"en","primary_location":{"id":"doi:10.2174/1570159x20666220901154034","doi":"https://doi.org/10.2174/1570159x20666220901154034","is_oa":false,"landing_page_url":"https://doi.org/10.2174/1570159x20666220901154034","pdf_url":null,"source":{"id":"https://openalex.org/S85221069","display_name":"Current Neuropharmacology","issn_l":"1570-159X","issn":["1570-159X","1875-6190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Neuropharmacology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10514530/pdf/CN-21-1840.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089740157","display_name":"Andr\u00e9 Ramos","orcid":"https://orcid.org/0000-0003-4449-3866","observed_orcids":["https://orcid.org/0000-0003-4449-3866"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Andr\u00e9 Ramos","raw_affiliation_strings":["Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004107336","display_name":"Natalli Granzotto","orcid":"https://orcid.org/0000-0002-4617-081X","observed_orcids":["https://orcid.org/0000-0002-4617-081X"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Natalli Granzotto","raw_affiliation_strings":["Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","Graduate Program of Pharmacology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]},{"raw_affiliation_string":"Graduate Program of Pharmacology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063285922","display_name":"Rafael Kremer","orcid":"https://orcid.org/0000-0001-6114-8832","observed_orcids":["https://orcid.org/0000-0001-6114-8832"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Rafael Kremer","raw_affiliation_strings":["Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","Graduate Program of Developmental and Cellular Biology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]},{"raw_affiliation_string":"Graduate Program of Developmental and Cellular Biology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090949966","display_name":"Ariela Ma\u00edna Boeder","orcid":"https://orcid.org/0000-0003-1991-7575","observed_orcids":["https://orcid.org/0000-0003-1991-7575"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ariela Ma\u00edna Boeder","raw_affiliation_strings":["Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","Graduate Program of Pharmacology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]},{"raw_affiliation_string":"Graduate Program of Pharmacology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083255789","display_name":"Julia F.P. de Ara\u00fajo","orcid":"https://orcid.org/0000-0003-1380-481X","observed_orcids":["https://orcid.org/0000-0003-1380-481X"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Julia Fernandez Pu\u00f1al de Ara\u00fajo","raw_affiliation_strings":["Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","Graduate Program of Developmental and Cellular Biology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]},{"raw_affiliation_string":"Graduate Program of Developmental and Cellular Biology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103178905","display_name":"Aline Guimar\u00e3es Pereira","orcid":"https://orcid.org/0000-0002-9169-3812","observed_orcids":["https://orcid.org/0000-0002-9169-3812"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Aline Guimar\u00e3es Pereira","raw_affiliation_strings":["Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","Graduate Program of Developmental and Cellular Biology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]},{"raw_affiliation_string":"Graduate Program of Developmental and Cellular Biology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068617040","display_name":"Geison Souza Iz\u00eddio","orcid":"https://orcid.org/0000-0001-7406-2923","observed_orcids":["https://orcid.org/0000-0001-7406-2923"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Geison Souza Iz\u00eddio","raw_affiliation_strings":["Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","Graduate Program of Developmental and Cellular Biology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","Graduate Program of Pharmacology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Behavior Genetics Laboratory, Department of Cell Biology, Embryology and Genetics, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]},{"raw_affiliation_string":"Graduate Program of Developmental and Cellular Biology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]},{"raw_affiliation_string":"Graduate Program of Pharmacology, Center of Biological Sciences, Federal\nUniversity of Santa Catarina, Florianopolis, Brazil","institution_ids":["https://openalex.org/I4104125"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5089740157"],"corresponding_institution_ids":["https://openalex.org/I4104125"],"apc_list":null,"apc_paid":null,"fwci":0.106,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.08672799,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"21","issue":"9","first_page":"1840","last_page":"1863"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.548799991607666,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.548799991607666,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.3562000095844269,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.036400001496076584,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/emotionality","display_name":"emotionality","score":0.9919999837875366},{"id":"https://openalex.org/keywords/laboratory-rats","display_name":"laboratory rats","score":0.6909999847412109},{"id":"https://openalex.org/keywords/quantitative-trait-loci","display_name":"quantitative trait loci","score":0.9070000052452087},{"id":"https://openalex.org/keywords/genetic-mapping","display_name":"gene mapping","score":0.7269999980926514},{"id":"https://openalex.org/keywords/quantitative-trait-genes","display_name":"quantitative trait genes","score":0.800000011920929},{"id":"https://openalex.org/keywords/behavioral-genetics","display_name":"behavioral genetics","score":0.675000011920929},{"id":"https://openalex.org/keywords/heritability-of-behavior","display_name":"heritability of behavior","score":0.7419999837875366},{"id":"https://openalex.org/keywords/chromosome-mapping","display_name":"chromosome mapping","score":0.6579999923706055},{"id":"https://openalex.org/keywords/psychiatric-genetics","display_name":"psychiatric genetics","score":0.48399999737739563},{"id":"https://openalex.org/keywords/zebrafish-model","display_name":"zebrafish model","score":0.7049999833106995}],"concepts":[{"id":"https://openalex.org/C81941488","wikidata":"https://www.wikidata.org/wiki/Q853421","display_name":"Quantitative trait locus","level":3,"score":0.8104449510574341},{"id":"https://openalex.org/C168862018","wikidata":"https://www.wikidata.org/wiki/Q5373805","display_name":"Emotionality","level":2,"score":0.6836661696434021},{"id":"https://openalex.org/C106934330","wikidata":"https://www.wikidata.org/wiki/Q1971873","display_name":"Trait","level":2,"score":0.6026842594146729},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5623783469200134},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49333706498146057},{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.42035210132598877},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.38118672370910645},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.36701148748397827},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.32920196652412415},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3243183493614197},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.22035816311836243},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1756928563117981},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004644","descriptor_name":"Emotions","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D040641","descriptor_name":"Quantitative Trait Loci","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.2174/1570159x20666220901154034","doi":"https://doi.org/10.2174/1570159x20666220901154034","is_oa":false,"landing_page_url":"https://doi.org/10.2174/1570159x20666220901154034","pdf_url":null,"source":{"id":"https://openalex.org/S85221069","display_name":"Current Neuropharmacology","issn_l":"1570-159X","issn":["1570-159X","1875-6190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Neuropharmacology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10514530","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10514530","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10514530/pdf/CN-21-1840.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Curr Neuropharmacol","raw_type":"Text"},{"id":"pmid:36056863","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36056863","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current neuropharmacology","raw_type":"Review"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10514530","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10514530","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10514530/pdf/CN-21-1840.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Curr Neuropharmacol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.46810001134872437}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320324147","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4294408705.pdf","grobid_xml":"https://content.openalex.org/works/W4294408705.grobid-xml"},"referenced_works_count":238,"referenced_works":["https://openalex.org/W41870505","https://openalex.org/W200306401","https://openalex.org/W215502054","https://openalex.org/W1489805892","https://openalex.org/W1499279387","https://openalex.org/W1509539509","https://openalex.org/W1514064771","https://openalex.org/W1535114875","https://openalex.org/W1537463019","https://openalex.org/W1540969441","https://openalex.org/W1556391613","https://openalex.org/W1584910068","https://openalex.org/W1627352250","https://openalex.org/W1703928389","https://openalex.org/W1876061808","https://openalex.org/W1891173294","https://openalex.org/W1906766611","https://openalex.org/W1925287805","https://openalex.org/W1958136033","https://openalex.org/W1964873942","https://openalex.org/W1967399741","https://openalex.org/W1967765572","https://openalex.org/W1967883762","https://openalex.org/W1967930242","https://openalex.org/W1968342512","https://openalex.org/W1968638036","https://openalex.org/W1968770494","https://openalex.org/W1969184610","https://openalex.org/W1971583765","https://openalex.org/W1972725067","https://openalex.org/W1976741643","https://openalex.org/W1978176455","https://openalex.org/W1978517482","https://openalex.org/W1979543168","https://openalex.org/W1980129154","https://openalex.org/W1981239255","https://openalex.org/W1981827479","https://openalex.org/W1983539322","https://openalex.org/W1986991051","https://openalex.org/W1987064543","https://openalex.org/W1988554226","https://openalex.org/W1990473626","https://openalex.org/W1991458644","https://openalex.org/W1993895564","https://openalex.org/W1996996506","https://openalex.org/W1997465995","https://openalex.org/W2000186580","https://openalex.org/W2002955199","https://openalex.org/W2003872525","https://openalex.org/W2004049159","https://openalex.org/W2007352042","https://openalex.org/W2008904303","https://openalex.org/W2009005948","https://openalex.org/W2009011848","https://openalex.org/W2009573330","https://openalex.org/W2012483246","https://openalex.org/W2012600569","https://openalex.org/W2012641732","https://openalex.org/W2014415629","https://openalex.org/W2015828365","https://openalex.org/W2016572676","https://openalex.org/W2017605183","https://openalex.org/W2019538882","https://openalex.org/W2020233428","https://openalex.org/W2021623374","https://openalex.org/W2024380057","https://openalex.org/W2027380968","https://openalex.org/W2028481539","https://openalex.org/W2030554335","https://openalex.org/W2032764699","https://openalex.org/W2036742353","https://openalex.org/W2036842321","https://openalex.org/W2041889311","https://openalex.org/W2042103448","https://openalex.org/W2042314330","https://openalex.org/W2043102375","https://openalex.org/W2045227722","https://openalex.org/W2046388159","https://openalex.org/W2046882658","https://openalex.org/W2047004970","https://openalex.org/W2048489884","https://openalex.org/W2051229639","https://openalex.org/W2051268271","https://openalex.org/W2051323855","https://openalex.org/W2053578357","https://openalex.org/W2054950529","https://openalex.org/W2056104468","https://openalex.org/W2056978406","https://openalex.org/W2057088571","https://openalex.org/W2059158680","https://openalex.org/W2059263974","https://openalex.org/W2059408119","https://openalex.org/W2060298854","https://openalex.org/W2060907334","https://openalex.org/W2061665487","https://openalex.org/W2066154408","https://openalex.org/W2066800291","https://openalex.org/W2066960840","https://openalex.org/W2066973390","https://openalex.org/W2067156824","https://openalex.org/W2067709496","https://openalex.org/W2068702161","https://openalex.org/W2069292822","https://openalex.org/W2071565372","https://openalex.org/W2071714684","https://openalex.org/W2072016770","https://openalex.org/W2072409961","https://openalex.org/W2074125037","https://openalex.org/W2074423792","https://openalex.org/W2074431470","https://openalex.org/W2075143387","https://openalex.org/W2075151381","https://openalex.org/W2075973436","https://openalex.org/W2079682826","https://openalex.org/W2080915629","https://openalex.org/W2082859469","https://openalex.org/W2082930529","https://openalex.org/W2083014091","https://openalex.org/W2083481513","https://openalex.org/W2084038751","https://openalex.org/W2086642462","https://openalex.org/W2088958599","https://openalex.org/W2089775476","https://openalex.org/W2094698442","https://openalex.org/W2100353278","https://openalex.org/W2100439546","https://openalex.org/W2102235987","https://openalex.org/W2106701745","https://openalex.org/W2113395651","https://openalex.org/W2116310686","https://openalex.org/W2116336801","https://openalex.org/W2116629441","https://openalex.org/W2120822816","https://openalex.org/W2123432920","https://openalex.org/W2125363737","https://openalex.org/W2126055692","https://openalex.org/W2127420837","https://openalex.org/W2138105350","https://openalex.org/W2141984765","https://openalex.org/W2147974031","https://openalex.org/W2149050611","https://openalex.org/W2152651094","https://openalex.org/W2153424164","https://openalex.org/W2154989101","https://openalex.org/W2156573769","https://openalex.org/W2159975710","https://openalex.org/W2162042784","https://openalex.org/W2162954233","https://openalex.org/W2164302084","https://openalex.org/W2166564802","https://openalex.org/W2167110017","https://openalex.org/W2167342331","https://openalex.org/W2168610467","https://openalex.org/W2176080020","https://openalex.org/W2192486264","https://openalex.org/W2195052748","https://openalex.org/W2225546673","https://openalex.org/W2235476089","https://openalex.org/W2252361719","https://openalex.org/W2282036305","https://openalex.org/W2293547289","https://openalex.org/W2294385208","https://openalex.org/W2298946842","https://openalex.org/W2316247155","https://openalex.org/W2321671016","https://openalex.org/W2334565880","https://openalex.org/W2395075857","https://openalex.org/W2412581616","https://openalex.org/W2418525743","https://openalex.org/W2470741179","https://openalex.org/W2475220077","https://openalex.org/W2492719736","https://openalex.org/W2511496957","https://openalex.org/W2515216596","https://openalex.org/W2529339498","https://openalex.org/W2565762773","https://openalex.org/W2585261722","https://openalex.org/W2590599688","https://openalex.org/W2593638387","https://openalex.org/W2604480906","https://openalex.org/W2604772716","https://openalex.org/W2722517739","https://openalex.org/W2740461424","https://openalex.org/W2746610102","https://openalex.org/W2748217278","https://openalex.org/W2750679304","https://openalex.org/W2751676383","https://openalex.org/W2765440541","https://openalex.org/W2768955286","https://openalex.org/W2772152127","https://openalex.org/W2783539475","https://openalex.org/W2784299524","https://openalex.org/W2787368117","https://openalex.org/W2793876735","https://openalex.org/W2799706195","https://openalex.org/W2802815532","https://openalex.org/W2803117777","https://openalex.org/W2807577035","https://openalex.org/W2808328764","https://openalex.org/W2833527792","https://openalex.org/W2883529992","https://openalex.org/W2889190991","https://openalex.org/W2890292817","https://openalex.org/W2891053092","https://openalex.org/W2892149536","https://openalex.org/W2894702920","https://openalex.org/W2901343265","https://openalex.org/W2902581052","https://openalex.org/W2902948311","https://openalex.org/W2937071524","https://openalex.org/W2945702369","https://openalex.org/W2945884889","https://openalex.org/W2947567620","https://openalex.org/W2950435626","https://openalex.org/W2966824380","https://openalex.org/W2974338024","https://openalex.org/W2985386410","https://openalex.org/W2989915604","https://openalex.org/W3004345850","https://openalex.org/W3011365376","https://openalex.org/W3011382181","https://openalex.org/W3015368500","https://openalex.org/W3015623027","https://openalex.org/W3015810055","https://openalex.org/W3018807579","https://openalex.org/W3022955356","https://openalex.org/W3045378301","https://openalex.org/W3085338548","https://openalex.org/W3086021116","https://openalex.org/W3092989312","https://openalex.org/W3106965934","https://openalex.org/W3120232329","https://openalex.org/W3122194942","https://openalex.org/W3126482743","https://openalex.org/W3207162111","https://openalex.org/W4211162815","https://openalex.org/W4254421198","https://openalex.org/W4298477317"],"related_works":["https://openalex.org/W2012600569","https://openalex.org/W7099215025","https://openalex.org/W2051229639","https://openalex.org/W1980129154","https://openalex.org/W2060916869","https://openalex.org/W2334565880","https://openalex.org/W1989374510","https://openalex.org/W1987063383","https://openalex.org/W7097583874","https://openalex.org/W1994637662"],"abstract_inverted_index":{"Abstract:":[0],"Scientists":[1],"have":[2,163],"systematically":[3],"investigated":[4],"the":[5,11,26,39,69,119,124,133,138,144,158,165,190,238],"hereditary":[6],"bases":[7],"of":[8,29,42,52,59,103,106,127,143,193,199],"behaviors":[9,44,78,170],"since":[10],"19th":[12],"century,":[13],"moved":[14],"by":[15,48],"either":[16],"evolutionary":[17],"questions":[18],"or":[19],"clinically-motivated":[20],"purposes.":[21],"The":[22,197],"pioneer":[23],"studies":[24],"on":[25,132,214],"genetic":[27,201],"selection":[28],"laboratory":[30,134],"animals":[31,219],"had":[32],"already":[33],"indicated,":[34],"one":[35,185],"hundred":[36],"years":[37],"ago,":[38],"immense":[40],"complexity":[41],"analyzing":[43],"that":[45,84],"were":[46],"influenced":[47],"a":[49,130,152],"large":[50],"number":[51],"small-effect":[53],"genes":[54],"and":[55,65,95,114,141,183,205,217],"an":[56],"incalculable":[57],"amount":[58],"environmental":[60],"factors.":[61],"Merging":[62],"Mendelian,":[63],"quantitative":[64],"molecular":[66,96,191],"approaches":[67],"in":[68,100,154,189,237],"1990s":[70],"made":[71,236],"it":[72],"possible":[73],"to":[74,79,123,171,180,230,234],"map":[75],"specific":[76],"rodent":[77],"known":[80],"chromosome":[81],"regions.":[82],"From":[83],"point":[85],"on,":[86],"Quantitative":[87,147],"Trait":[88,148],"Locus":[89],"(QTL)":[90],"analyses":[91],"coupled":[92],"with":[93,129],"behavioral":[94,125],"techniques,":[97],"which":[98],"involved":[99],"vivo":[101],"isolation":[102],"relevant":[104],"blocks":[105],"genes,":[107],"opened":[108],"new":[109],"avenues":[110],"for":[111,146],"gene":[112],"mapping":[113],"characterization.":[115],"This":[116],"review":[117],"examines":[118],"QTL":[120],"strategy":[121],"applied":[122],"study":[126],"emotionality,":[128],"focus":[131],"rat.":[135],"We":[136],"discuss":[137],"challenges,":[139],"advances":[140],"limitations":[142],"search":[145],"Genes":[149],"(QTG)":[150],"playing":[151],"role":[153],"regulating":[155],"emotionality.":[156],"For":[157],"past":[159],"25":[160],"years,":[161],"we":[162],"marched":[164],"long":[166],"journey":[167],"from":[168],"emotionality-related":[169],"genes.":[172],"In":[173],"this":[174],"context,":[175],"our":[176],"experiences":[177],"are":[178,208,223,228],"used":[179],"illustrate":[181],"why":[182],"how":[184],"should":[186],"move":[187],"forward":[188],"understanding":[192],"complex":[194],"psychiatric":[195],"illnesses.":[196],"promise":[198],"exploring":[200],"links":[202],"between":[203],"immunological":[204],"emotional":[206],"responses":[207],"also":[209,224],"discussed.":[210],"New":[211],"strategies":[212],"based":[213],"humans,":[215],"rodents":[216],"other":[218],"(such":[220],"as":[221,226],"zebrafish)":[222],"acknowledged,":[225],"they":[227],"likely":[229],"allow":[231],"substantial":[232],"progress":[233],"be":[235],"near":[239],"future.":[240]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-09-03T00:00:00"}