{"id":"https://openalex.org/W4294032373","doi":"https://doi.org/10.1038/s41598-022-18826-0","title":"Hepcidin discriminates sepsis from other critical illness at admission to intensive care","display_name":"Hepcidin discriminates sepsis from other critical illness at admission to intensive care","publication_year":2022,"publication_date":"2022-09-01","ids":{"openalex":"https://openalex.org/W4294032373","doi":"https://doi.org/10.1038/s41598-022-18826-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/36050405","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9434539"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-022-18826-0","doi":"https://doi.org/10.1038/s41598-022-18826-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-022-18826-0","pdf_url":"https://www.nature.com/articles/s41598-022-18826-0.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-022-18826-0.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054041590","display_name":"Jon Olinder","orcid":"https://orcid.org/0000-0002-3223-6769","observed_orcids":["https://orcid.org/0000-0002-3223-6769"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210132623","display_name":"Helsingborgs lasarett","ror":"https://ror.org/03am3jt82","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210132623"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Jon Olinder","raw_affiliation_strings":["Department of Infectious Diseases, Helsingborg Hospital, Helsingborg, Sweden. jon.olinder@skane.se","Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden. jon.olinder@skane.se","Department of Infectious Diseases, Helsingborg Hospital, Helsingborg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases, Helsingborg Hospital, Helsingborg, Sweden. jon.olinder@skane.se","institution_ids":["https://openalex.org/I4210132623"]},{"raw_affiliation_string":"Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden. jon.olinder@skane.se","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Department of Infectious Diseases, Helsingborg Hospital, Helsingborg, Sweden","institution_ids":["https://openalex.org/I4210132623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013348900","display_name":"Alex B\u00f6rjesson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Alex B\u00f6rjesson","raw_affiliation_strings":["Department of Psychiatry, Karlskrona, Sweden","Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Karlskrona, Sweden","institution_ids":[]},{"raw_affiliation_string":"Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037786465","display_name":"Jakob Norrman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jakob Norrman","raw_affiliation_strings":["Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden","Husl\u00e4karna Falkenberg, Falkenberg, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Husl\u00e4karna Falkenberg, Falkenberg, Sweden","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030830879","display_name":"Tobias West","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210132623","display_name":"Helsingborgs lasarett","ror":"https://ror.org/03am3jt82","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210132623"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Tobias West","raw_affiliation_strings":["Department of Internal Medicine, Helsingborg Hospital, Helsingborg, Sweden","Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Helsingborg Hospital, Helsingborg, Sweden","institution_ids":["https://openalex.org/I4210132623"]},{"raw_affiliation_string":"Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023867108","display_name":"Joakim Carlstr\u00f6m","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Joakim Carlstr\u00f6m","raw_affiliation_strings":["Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden","Malm\u00f6 Addiction Center, Malm\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Malm\u00f6 Addiction Center, Malm\u00f6, Sweden","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Alexander Gustafsson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210085923","display_name":"H\u00e4ssleholms Sjukhus","ror":"https://ror.org/004vnpm81","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210085923"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Alexander Gustafsson","raw_affiliation_strings":["Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden","Hospital of H\u00e4ssleholm, H\u00e4ssleholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Hospital of H\u00e4ssleholm, H\u00e4ssleholm, Sweden","institution_ids":["https://openalex.org/I4210085923"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019355432","display_name":"Martin Annborn","orcid":"https://orcid.org/0000-0002-1074-9512","observed_orcids":["https://orcid.org/0000-0002-1074-9512"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210132623","display_name":"Helsingborgs lasarett","ror":"https://ror.org/03am3jt82","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210132623"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Martin Annborn","raw_affiliation_strings":["Department of Intensive Care Medicine, Helsingborg Hospital, Helsingborg, Sweden","Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Intensive Care Medicine, Helsingborg Hospital, Helsingborg, Sweden","institution_ids":["https://openalex.org/I4210132623"]},{"raw_affiliation_string":"Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085263597","display_name":"Heiko Herwald","orcid":"https://orcid.org/0000-0002-8111-2842","observed_orcids":["https://orcid.org/0000-0002-8111-2842"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Heiko Herwald","raw_affiliation_strings":["Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035170774","display_name":"C\u00e9cilia Ryd\u00e8n","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I4210132623","display_name":"Helsingborgs lasarett","ror":"https://ror.org/03am3jt82","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210132623"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Cecilia Ryd\u00e9n","raw_affiliation_strings":["Department of Infectious Diseases, Helsingborg Hospital, Helsingborg, Sweden","Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases, Helsingborg Hospital, Helsingborg, Sweden","institution_ids":["https://openalex.org/I4210132623"]},{"raw_affiliation_string":"Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5054041590"],"corresponding_institution_ids":["https://openalex.org/I187531555","https://openalex.org/I4210132623"],"apc_list":{"value":2190,"currency":"USD","value_usd":2190},"apc_paid":{"value":2190,"currency":"USD","value_usd":2190},"fwci":3.5805,"has_fulltext":true,"cited_by_count":23,"citation_normalized_percentile":{"value":0.93107903,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"12","issue":"1","first_page":"14857","last_page":"14857"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepcidin","display_name":"hepcidin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.9879999756813049},{"id":"https://openalex.org/keywords/sepsis-diagnosis","display_name":"sepsis diagnosis","score":0.7519999742507935},{"id":"https://openalex.org/keywords/sepsis-mortality-prediction","display_name":"sepsis mortality prediction","score":0.6309999823570251},{"id":"https://openalex.org/keywords/intensive-care-unit-admission","display_name":"intensive care unit admission","score":0.7310000061988831},{"id":"https://openalex.org/keywords/heparin-binding-protein","display_name":"heparin-binding protein","score":0.9160000085830688},{"id":"https://openalex.org/keywords/saps-iii","display_name":"SAPS 3","score":0.746999979019165},{"id":"https://openalex.org/keywords/critical-illness","display_name":"critical illness","score":0.5149999856948853},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7179999947547913},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.796999990940094}],"concepts":[{"id":"https://openalex.org/C2776768029","wikidata":"https://www.wikidata.org/wiki/Q14882371","display_name":"Hepcidin","level":3,"score":0.807707667350769},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.7866173982620239},{"id":"https://openalex.org/C2993568657","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critical illness","level":3,"score":0.7667250633239746},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.6273137331008911},{"id":"https://openalex.org/C2987404301","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care","level":2,"score":0.5845632553100586},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5804233551025391},{"id":"https://openalex.org/C10936531","wikidata":"https://www.wikidata.org/wiki/Q786600","display_name":"Procalcitonin","level":3,"score":0.45975184440612793},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.41803044080734253},{"id":"https://openalex.org/C2991859549","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critically ill","level":2,"score":0.3670072555541992},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2680947780609131},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.14291775226593018}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003422","descriptor_name":"Critical Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007362","descriptor_name":"Intensive Care Units","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012772","descriptor_name":"Shock, Septic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012772","descriptor_name":"Shock, Septic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016638","descriptor_name":"Critical Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D064451","descriptor_name":"Hepcidins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D064451","descriptor_name":"Hepcidins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41598-022-18826-0","doi":"https://doi.org/10.1038/s41598-022-18826-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-022-18826-0","pdf_url":"https://www.nature.com/articles/s41598-022-18826-0.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmid:36050405","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36050405","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9434539","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9434539/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:7c9394e79e934afa84b5e3a85ec00815","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7c9394e79e934afa84b5e3a85ec00815","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)","raw_type":"article"},{"id":"pmh:oai:lup.lub.lu.se:0f4489f6-6fce-46e4-8e73-d6f5c6cc9010","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/0f4489f6-6fce-46e4-8e73-d6f5c6cc9010","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 2045-2322","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1038/s41598-022-18826-0","doi":"https://doi.org/10.1038/s41598-022-18826-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-022-18826-0","pdf_url":"https://www.nature.com/articles/s41598-022-18826-0.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321806","display_name":"Lunds Universitet","ror":"https://ror.org/012a77v79"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4294032373.pdf","grobid_xml":"https://content.openalex.org/works/W4294032373.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W1141274631","https://openalex.org/W1761222131","https://openalex.org/W1907040326","https://openalex.org/W1929119278","https://openalex.org/W1969230979","https://openalex.org/W1979681234","https://openalex.org/W1990904157","https://openalex.org/W2006000223","https://openalex.org/W2011341739","https://openalex.org/W2019834345","https://openalex.org/W2025063713","https://openalex.org/W2027624389","https://openalex.org/W2029275026","https://openalex.org/W2029441236","https://openalex.org/W2030300388","https://openalex.org/W2056426465","https://openalex.org/W2059080581","https://openalex.org/W2061035099","https://openalex.org/W2064778552","https://openalex.org/W2073419951","https://openalex.org/W2075875418","https://openalex.org/W2110317531","https://openalex.org/W2114472373","https://openalex.org/W2127774299","https://openalex.org/W2132155262","https://openalex.org/W2136298973","https://openalex.org/W2152946780","https://openalex.org/W2153154688","https://openalex.org/W2162747635","https://openalex.org/W2163230336","https://openalex.org/W2164990391","https://openalex.org/W2170885365","https://openalex.org/W2182981871","https://openalex.org/W2280404143","https://openalex.org/W2305218600","https://openalex.org/W2324521520","https://openalex.org/W2407889154","https://openalex.org/W2528711333","https://openalex.org/W2580449060","https://openalex.org/W2581605534","https://openalex.org/W2603079123","https://openalex.org/W2746067197","https://openalex.org/W2763575346","https://openalex.org/W2768589170","https://openalex.org/W2800916723","https://openalex.org/W2801429697","https://openalex.org/W2883566781","https://openalex.org/W2884364493","https://openalex.org/W2885615325","https://openalex.org/W2890270208","https://openalex.org/W2901022935","https://openalex.org/W2911814182","https://openalex.org/W2945246783","https://openalex.org/W2948029220","https://openalex.org/W2949976134","https://openalex.org/W2998853022","https://openalex.org/W3013265183","https://openalex.org/W3023757607","https://openalex.org/W3033683066","https://openalex.org/W3045454797","https://openalex.org/W3085107450","https://openalex.org/W3087096824","https://openalex.org/W3087758117","https://openalex.org/W4243211588"],"related_works":["https://openalex.org/W4396745802","https://openalex.org/W2900983784","https://openalex.org/W4411969223","https://openalex.org/W4396761475","https://openalex.org/W2884364493","https://openalex.org/W4310291841","https://openalex.org/W2987468496","https://openalex.org/W4411786816","https://openalex.org/W1990904157","https://openalex.org/W4408052844"],"abstract_inverted_index":{"Initial":[0],"differential":[1],"diagnosis":[2],"and":[3,42,75,83,99,103,164,184,203],"prognosis":[4],"for":[5,23,45,71,118,208],"patients":[6,49,111,141,168,180,198],"admitted":[7,50,199],"to":[8,51,62,114,200],"intensive":[9,53],"care":[10,54],"with":[11,169],"suspected":[12],"sepsis":[13,119,196],"remain":[14],"arduous.":[15],"Hepcidin":[16,124,171],"has":[17,204],"emerged":[18],"as":[19,39],"a":[20,40,152,205],"potential":[21],"biomarker":[22],"sepsis.":[24,46,170],"Here":[25],"we":[26],"report":[27],"data":[28,188],"on":[29],"the":[30,52,63,110,116,132,136,201],"relevance":[31],"of":[32,34,109,195],"levels":[33,82,125,143,163,172,192],"hepcidin":[35,76,142,162,191],"versus":[36],"other":[37],"biomarkers":[38,85],"diagnostic":[41],"prognostic":[43,206],"tool":[44],"164":[47],"adult":[48],"unit":[55],"(ICU)":[56],"within":[57],"24":[58,148],"h":[59,149],"upon":[60],"arrival":[61],"hospital":[64],"were":[65,86,90,96,112,128,175],"included.":[66],"Blood":[67,88],"samples":[68],"collected":[69],"daily":[70,98],"seven":[72],"consecutive":[73],"days":[74],"levels,":[77],"heparin":[78],"binding":[79],"protein":[80],"(HBP)":[81],"standard":[84],"determined.":[87],"cultures":[89],"initiated":[91],"at":[92,126,147,173],"inclusion.":[93],"Clinical":[94],"scores":[95],"evaluated":[97],"mortality":[100],"after":[101],"28-":[102],"180-days":[104,183],"was":[105,159],"recorded.":[106],"One":[107],"hundred":[108],"found":[113],"fulfil":[115],"criteria":[117],"whereas":[120],"64":[121],"did":[122],"not.":[123],"admission":[127],"significantly":[129,145,176],"higher":[130,177],"in":[131,135,167,197],"septic":[133,140,179],"than":[134],"non-septic":[137],"patients.":[138],"In":[139],"declined":[144],"already":[146],"followed":[150],"by":[151],"steady":[153],"decline.":[154],"A":[155],"significant":[156],"negative":[157],"correlation":[158],"observed":[160],"between":[161],"SAPS":[165],"3":[166],"inclusion":[174],"among":[178],"that":[181,190],"survived":[182],"predicted":[185],"mortality.":[186,209],"Our":[187],"show":[189],"are":[193],"indicative":[194],"ICU":[202],"value":[207]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-09-01T00:00:00"}