{"id":"https://openalex.org/W4293585366","doi":"https://doi.org/10.1016/j.atherosclerosis.2022.06.200","title":"Circulating natural killer cells in patients with symptomatic atherosclerosis acquire the CD9+CD49A pro-inflammatory phenotype and support M1-like macrophage polarization","display_name":"Circulating natural killer cells in patients with symptomatic atherosclerosis acquire the CD9+CD49A pro-inflammatory phenotype and support M1-like macrophage polarization","publication_year":2022,"publication_date":"2022-08-01","ids":{"openalex":"https://openalex.org/W4293585366","doi":"https://doi.org/10.1016/j.atherosclerosis.2022.06.200"},"language":"en","primary_location":{"id":"doi:10.1016/j.atherosclerosis.2022.06.200","doi":"https://doi.org/10.1016/j.atherosclerosis.2022.06.200","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.atherosclerosis.2022.06.200","pdf_url":"http://www.atherosclerosis-journal.com/article/S0021915022004877/pdf","source":{"id":"https://openalex.org/S206830620","display_name":"Atherosclerosis","issn_l":"0021-9150","issn":["0021-9150","1879-1484"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Atherosclerosis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.atherosclerosis-journal.com/article/S0021915022004877/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087143239","display_name":"Martina Cucchiara","orcid":"https://orcid.org/0000-0003-0030-5149","observed_orcids":["https://orcid.org/0000-0003-0030-5149"]},"institutions":[{"id":"https://openalex.org/I115752224","display_name":"University of Insubria","ror":"https://ror.org/00s409261","country_code":"IT","type":"education","lineage":["https://openalex.org/I115752224"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Cucchiara","raw_affiliation_strings":["Department Of Biotechnology And Life Sciences, University of Insubria, Varese, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Of Biotechnology And Life Sciences, University of Insubria, Varese, Italy","institution_ids":["https://openalex.org/I115752224"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009460285","display_name":"Matteo Gallazzi","orcid":"https://orcid.org/0000-0001-6662-9352","observed_orcids":["https://orcid.org/0000-0001-6662-9352"]},"institutions":[{"id":"https://openalex.org/I115752224","display_name":"University of Insubria","ror":"https://ror.org/00s409261","country_code":"IT","type":"education","lineage":["https://openalex.org/I115752224"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Gallazzi","raw_affiliation_strings":["Department Of Biotechnology And Life Sciences, University of Insubria, Varese, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Of Biotechnology And Life Sciences, University of Insubria, Varese, Italy","institution_ids":["https://openalex.org/I115752224"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020045875","display_name":"S. Losa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094922","display_name":"MultiMedica","ror":"https://ror.org/01h8ey223","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094922","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S. Losa","raw_affiliation_strings":["Unit Of Vascular Surgery, IRCCS MultiMedica, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit Of Vascular Surgery, IRCCS MultiMedica, Milan, Italy","institution_ids":["https://openalex.org/I4210094922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084531515","display_name":"V. Carlini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094922","display_name":"MultiMedica","ror":"https://ror.org/01h8ey223","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094922","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"V. Carlini","raw_affiliation_strings":["Unit Of Molecular Pathology, Biochemistry, And Immunology, IRCCS MultiMedica, Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit Of Molecular Pathology, Biochemistry, And Immunology, IRCCS MultiMedica, Milano, Italy","institution_ids":["https://openalex.org/I4210094922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051857050","display_name":"T. Mazzullo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094922","display_name":"MultiMedica","ror":"https://ror.org/01h8ey223","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094922","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"T. Mazzullo","raw_affiliation_strings":["Nephrology And Dialysis Unit, IRCCS MultiMedica, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nephrology And Dialysis Unit, IRCCS MultiMedica, Milan, Italy","institution_ids":["https://openalex.org/I4210094922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021987497","display_name":"Massimiliano Martelli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094922","display_name":"MultiMedica","ror":"https://ror.org/01h8ey223","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094922","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Martelli","raw_affiliation_strings":["Unit Of Vascular Surgery, IRCCS MultiMedica, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit Of Vascular Surgery, IRCCS MultiMedica, Milan, Italy","institution_ids":["https://openalex.org/I4210094922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107301111","display_name":"Douglas McClain Noonan","orcid":"https://orcid.org/0000-0001-8058-0719","observed_orcids":["https://orcid.org/0000-0001-8058-0719"]},"institutions":[{"id":"https://openalex.org/I115752224","display_name":"University of Insubria","ror":"https://ror.org/00s409261","country_code":"IT","type":"education","lineage":["https://openalex.org/I115752224"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"D.M. Noonan","raw_affiliation_strings":["Department Of Biotechnology And Life Sciences, University of Insubria, Varese, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Of Biotechnology And Life Sciences, University of Insubria, Varese, Italy","institution_ids":["https://openalex.org/I115752224"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037695785","display_name":"A. Bruno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094922","display_name":"MultiMedica","ror":"https://ror.org/01h8ey223","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094922","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Bruno","raw_affiliation_strings":["Laboratory Of Innate Immunity, IRCCS MultiMedica, Italy, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Of Innate Immunity, IRCCS MultiMedica, Italy, Italy","institution_ids":["https://openalex.org/I4210094922"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033954391","display_name":"A. Albini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094922","display_name":"MultiMedica","ror":"https://ror.org/01h8ey223","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094922","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Albini","raw_affiliation_strings":["Laboratory Of Vascular Biology And Angiogenesis, IRCCS MultiMedica, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Of Vascular Biology And Angiogenesis, IRCCS MultiMedica, Milan, Italy","institution_ids":["https://openalex.org/I4210094922"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3520,"currency":"USD","value_usd":3520},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.09144173,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"355","issue":null,"first_page":"39","last_page":"39"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.788100004196167,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.788100004196167,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.20559999346733093,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.9649999737739563},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.4779999852180481},{"id":"https://openalex.org/keywords/monocytes","display_name":"monocytes","score":0.48899999260902405},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.9430000185966492},{"id":"https://openalex.org/keywords/nk-cell-function","display_name":"NK cell function","score":0.5239999890327454},{"id":"https://openalex.org/keywords/peripheral-blood-nk-cells","display_name":"peripheral blood NK cells","score":0.6980000138282776}],"concepts":[{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.6795521974563599},{"id":"https://openalex.org/C2781184567","wikidata":"https://www.wikidata.org/wiki/Q107244","display_name":"Monocyte","level":2,"score":0.622826337814331},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6160733699798584},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.48879334330558777},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.482864648103714},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.47813546657562256},{"id":"https://openalex.org/C2776682551","wikidata":"https://www.wikidata.org/wiki/Q21072584","display_name":"Macrophage polarization","level":4,"score":0.47422242164611816},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.44793379306793213},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.4452049136161804},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40378817915916443},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3789859712123871},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.34658128023147583},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.atherosclerosis.2022.06.200","doi":"https://doi.org/10.1016/j.atherosclerosis.2022.06.200","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.atherosclerosis.2022.06.200","pdf_url":"http://www.atherosclerosis-journal.com/article/S0021915022004877/pdf","source":{"id":"https://openalex.org/S206830620","display_name":"Atherosclerosis","issn_l":"0021-9150","issn":["0021-9150","1879-1484"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Atherosclerosis","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.atherosclerosis.2022.06.200","doi":"https://doi.org/10.1016/j.atherosclerosis.2022.06.200","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.atherosclerosis.2022.06.200","pdf_url":"http://www.atherosclerosis-journal.com/article/S0021915022004877/pdf","source":{"id":"https://openalex.org/S206830620","display_name":"Atherosclerosis","issn_l":"0021-9150","issn":["0021-9150","1879-1484"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Atherosclerosis","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4293585366.pdf","grobid_xml":"https://content.openalex.org/works/W4293585366.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7008774919","https://openalex.org/W7163579403","https://openalex.org/W7165206402","https://openalex.org/W4206255691","https://openalex.org/W1640953891","https://openalex.org/W2743626096","https://openalex.org/W82508545","https://openalex.org/W1480838044","https://openalex.org/W6930852585","https://openalex.org/W2107900528"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2022-08-30T00:00:00"}