{"id":"https://openalex.org/W4293579142","doi":"https://doi.org/10.1016/j.atherosclerosis.2022.06.135","title":"The impact of RIPK1 kinase inhibition on atherogenesis","display_name":"The impact of RIPK1 kinase inhibition on atherogenesis","publication_year":2022,"publication_date":"2022-08-01","ids":{"openalex":"https://openalex.org/W4293579142","doi":"https://doi.org/10.1016/j.atherosclerosis.2022.06.135"},"language":"en","primary_location":{"id":"doi:10.1016/j.atherosclerosis.2022.06.135","doi":"https://doi.org/10.1016/j.atherosclerosis.2022.06.135","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.atherosclerosis.2022.06.135","pdf_url":null,"source":{"id":"https://openalex.org/S206830620","display_name":"Atherosclerosis","issn_l":"0021-9150","issn":["0021-9150","1879-1484"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Atherosclerosis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080874961","display_name":"Pauline Puylaert","orcid":"https://orcid.org/0000-0002-0316-2916","observed_orcids":["https://orcid.org/0000-0002-0316-2916"]},"institutions":[{"id":"https://openalex.org/I149213910","display_name":"University of Antwerp","ror":"https://ror.org/008x57b05","country_code":"BE","type":"education","lineage":["https://openalex.org/I149213910"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"P. Puylaert","raw_affiliation_strings":["Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium","institution_ids":["https://openalex.org/I149213910"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070148989","display_name":"Isabelle Coornaert","orcid":"https://orcid.org/0000-0002-5041-8590","observed_orcids":["https://orcid.org/0000-0002-5041-8590"]},"institutions":[{"id":"https://openalex.org/I149213910","display_name":"University of Antwerp","ror":"https://ror.org/008x57b05","country_code":"BE","type":"education","lineage":["https://openalex.org/I149213910"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"I. Coornaert","raw_affiliation_strings":["Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium","institution_ids":["https://openalex.org/I149213910"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059546075","display_name":"Cedric H. G. Neutel","orcid":"https://orcid.org/0000-0001-7074-226X","observed_orcids":["https://orcid.org/0000-0001-7074-226X"]},"institutions":[{"id":"https://openalex.org/I149213910","display_name":"University of Antwerp","ror":"https://ror.org/008x57b05","country_code":"BE","type":"education","lineage":["https://openalex.org/I149213910"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"C.H.G. Neutel","raw_affiliation_strings":["Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium","institution_ids":["https://openalex.org/I149213910"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018449456","display_name":"Mathieu J.M. Bertrand","orcid":"https://orcid.org/0000-0001-9000-0626","observed_orcids":["https://orcid.org/0000-0001-9000-0626"]},"institutions":[{"id":"https://openalex.org/I4210139803","display_name":"VIB-UGent Center for Inflammation Research","ror":"https://ror.org/04q4ydz28","country_code":"BE","type":"facility","lineage":["https://openalex.org/I2802017950","https://openalex.org/I32597200","https://openalex.org/I4210139803"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"M.J.M. Bertrand","raw_affiliation_strings":["Center For Inflammation Research, VIB, Ghent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center For Inflammation Research, VIB, Ghent, Belgium","institution_ids":["https://openalex.org/I4210139803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072677920","display_name":"Pieter\u2010Jan Guns","orcid":"https://orcid.org/0000-0002-8640-6620","observed_orcids":["https://orcid.org/0000-0002-8640-6620"]},"institutions":[{"id":"https://openalex.org/I149213910","display_name":"University of Antwerp","ror":"https://ror.org/008x57b05","country_code":"BE","type":"education","lineage":["https://openalex.org/I149213910"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"P.-J. Guns","raw_affiliation_strings":["Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium","institution_ids":["https://openalex.org/I149213910"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059862918","display_name":"Guido R.Y. De Meyer","orcid":"https://orcid.org/0000-0003-3848-8702","observed_orcids":["https://orcid.org/0000-0003-3848-8702"]},"institutions":[{"id":"https://openalex.org/I149213910","display_name":"University of Antwerp","ror":"https://ror.org/008x57b05","country_code":"BE","type":"education","lineage":["https://openalex.org/I149213910"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"G. De Meyer","raw_affiliation_strings":["Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium","institution_ids":["https://openalex.org/I149213910"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076009877","display_name":"Wim Martinet","orcid":"https://orcid.org/0000-0003-1967-9343","observed_orcids":["https://orcid.org/0000-0003-1967-9343"]},"institutions":[{"id":"https://openalex.org/I149213910","display_name":"University of Antwerp","ror":"https://ror.org/008x57b05","country_code":"BE","type":"education","lineage":["https://openalex.org/I149213910"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"M. Wim","raw_affiliation_strings":["Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab Of Physiopharmacology, University of Antwerp, Wilrijk, Belgium","institution_ids":["https://openalex.org/I149213910"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3520,"currency":"USD","value_usd":3520},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"355","issue":null,"first_page":"17","last_page":"18"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.9351000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.9351000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.040300000458955765,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.008700000122189522,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atherogenesis","display_name":"atherogenesis","score":0.8859999775886536},{"id":"https://openalex.org/keywords/necroptosis","display_name":"necroptosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.7250000238418579},{"id":"https://openalex.org/keywords/apoe-deficient-mice","display_name":"ApoE-deficient mice","score":0.828000009059906}],"concepts":[{"id":"https://openalex.org/C94030615","wikidata":"https://www.wikidata.org/wiki/Q3346925","display_name":"Necroptosis","level":4,"score":0.7521429061889648},{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.6816499829292297},{"id":"https://openalex.org/C2776550021","wikidata":"https://www.wikidata.org/wiki/Q18033276","display_name":"RIPK1","level":5,"score":0.5814400315284729},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5680432915687561},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5365204215049744},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.53401118516922},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5098485350608826},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.43169906735420227},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3036839962005615},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25867605209350586},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.24764469265937805},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17939040064811707},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.atherosclerosis.2022.06.135","doi":"https://doi.org/10.1016/j.atherosclerosis.2022.06.135","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.atherosclerosis.2022.06.135","pdf_url":null,"source":{"id":"https://openalex.org/S206830620","display_name":"Atherosclerosis","issn_l":"0021-9150","issn":["0021-9150","1879-1484"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Atherosclerosis","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4225132474","https://openalex.org/W4281900986","https://openalex.org/W3132577274","https://openalex.org/W3210678628","https://openalex.org/W3106805418","https://openalex.org/W7212055483","https://openalex.org/W3117800959","https://openalex.org/W2807623955","https://openalex.org/W2794609742","https://openalex.org/W7100469218"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2022-08-30T00:00:00"}