{"id":"https://openalex.org/W4293414971","doi":"https://doi.org/10.3390/biomedicines10092088","title":"Ribosome-Directed Therapies in Cancer","display_name":"Ribosome-Directed Therapies in Cancer","publication_year":2022,"publication_date":"2022-08-26","ids":{"openalex":"https://openalex.org/W4293414971","doi":"https://doi.org/10.3390/biomedicines10092088","pmid":"https://pubmed.ncbi.nlm.nih.gov/36140189","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9495564"},"language":"en","primary_location":{"id":"doi:10.3390/biomedicines10092088","doi":"https://doi.org/10.3390/biomedicines10092088","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biomedicines10092088","pdf_url":"https://www.mdpi.com/2227-9059/10/9/2088/pdf?version=1662543063","source":{"id":"https://openalex.org/S2737005842","display_name":"Biomedicines","issn_l":"2227-9059","issn":["2227-9059"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2227-9059/10/9/2088/pdf?version=1662543063","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059404446","display_name":"Gazmend Temaj","orcid":"https://orcid.org/0000-0003-4807-2938","observed_orcids":["https://orcid.org/0000-0003-4807-2938"]},"institutions":[{"id":"https://openalex.org/I4210086961","display_name":"University for Business and Technology","ror":"https://ror.org/00033n668","country_code":"XK","type":"education","lineage":["https://openalex.org/I4210086961"]}],"countries":["XK"],"is_corresponding":true,"raw_author_name":"Gazmend Temaj","raw_affiliation_strings":["Faculty of Pharmacy, College UBT, 10000 Prishtina, Kosovo"],"raw_orcid":"https://orcid.org/0000-0003-4807-2938","affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy, College UBT, 10000 Prishtina, Kosovo","institution_ids":["https://openalex.org/I4210086961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012749696","display_name":"Silvia Chichiarelli","orcid":"https://orcid.org/0000-0002-5682-0353","observed_orcids":["https://orcid.org/0000-0002-5682-0353"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Silvia Chichiarelli","raw_affiliation_strings":["Department of Biochemical Sciences \u201cA.Rossi-Fanelli\u201d, Sapienza University of Rome, 00185 Rome, Italy"],"raw_orcid":"https://orcid.org/0000-0002-5682-0353","affiliations":[{"raw_affiliation_string":"Department of Biochemical Sciences \u201cA.Rossi-Fanelli\u201d, Sapienza University of Rome, 00185 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082988605","display_name":"Margherita Eufemi","orcid":"https://orcid.org/0000-0001-9153-972X","observed_orcids":["https://orcid.org/0000-0001-9153-972X"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Margherita Eufemi","raw_affiliation_strings":["Department of Biochemical Sciences \u201cA.Rossi-Fanelli\u201d, Sapienza University of Rome, 00185 Rome, Italy"],"raw_orcid":"https://orcid.org/0000-0001-9153-972X","affiliations":[{"raw_affiliation_string":"Department of Biochemical Sciences \u201cA.Rossi-Fanelli\u201d, Sapienza University of Rome, 00185 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025499313","display_name":"Fabio Altieri F.","orcid":"https://orcid.org/0000-0002-6546-2738","observed_orcids":["https://orcid.org/0000-0002-6546-2738"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fabio Altieri","raw_affiliation_strings":["Department of Biochemical Sciences \u201cA.Rossi-Fanelli\u201d, Sapienza University of Rome, 00185 Rome, Italy"],"raw_orcid":"https://orcid.org/0000-0002-6546-2738","affiliations":[{"raw_affiliation_string":"Department of Biochemical Sciences \u201cA.Rossi-Fanelli\u201d, Sapienza University of Rome, 00185 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055957329","display_name":"Rifat Had\u017eiselimovi\u0107","orcid":"https://orcid.org/0000-0002-6590-8824","observed_orcids":["https://orcid.org/0000-0002-6590-8824"]},"institutions":[{"id":"https://openalex.org/I104817121","display_name":"University of Sarajevo","ror":"https://ror.org/02hhwgd43","country_code":"BA","type":"education","lineage":["https://openalex.org/I104817121"]}],"countries":["BA"],"is_corresponding":false,"raw_author_name":"Rifat Hadziselimovic","raw_affiliation_strings":["Faculty of Science, University of Sarajevo, 71000 Sarajevo, Bosnia and Herzegovina"],"raw_orcid":"https://orcid.org/0000-0002-6590-8824","affiliations":[{"raw_affiliation_string":"Faculty of Science, University of Sarajevo, 71000 Sarajevo, Bosnia and Herzegovina","institution_ids":["https://openalex.org/I104817121"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073515685","display_name":"Ammad Ahmad Farooq\u0131","orcid":"https://orcid.org/0000-0003-2899-5014","observed_orcids":["https://orcid.org/0000-0003-2899-5014","https://orcid.org/0000-0003-2209-7483"]},"institutions":[{"id":"https://openalex.org/I4210159891","display_name":"Institute of Biomedical and Genetic Engineering","ror":"https://ror.org/05h6f5h95","country_code":"PK","type":"education","lineage":["https://openalex.org/I4210159891"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Ammad Ahmad Farooqi","raw_affiliation_strings":["Institute of Biomedical and Genetic Engineering (IBGE), Islamabad 54000, Pakistan"],"raw_orcid":"https://orcid.org/0000-0003-2209-7483","affiliations":[{"raw_affiliation_string":"Institute of Biomedical and Genetic Engineering (IBGE), Islamabad 54000, Pakistan","institution_ids":["https://openalex.org/I4210159891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112042458","display_name":"\u0130lhan Yayl\u0131m","orcid":"https://orcid.org/0000-0001-8998-2028","observed_orcids":["https://orcid.org/0000-0001-8998-2028"]},"institutions":[{"id":"https://openalex.org/I67581229","display_name":"Istanbul University","ror":"https://ror.org/03a5qrr21","country_code":"TR","type":"education","lineage":["https://openalex.org/I67581229"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ilhan Yaylim","raw_affiliation_strings":["Department of Molecular Medicine, Aziz Sancar Institute of Experimental Medicine, Istanbul University, \u00c7apa, Istanbul 34280, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine, Aziz Sancar Institute of Experimental Medicine, Istanbul University, \u00c7apa, Istanbul 34280, Turkey","institution_ids":["https://openalex.org/I67581229"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065222117","display_name":"Luciano Saso","orcid":"https://orcid.org/0000-0003-4530-8706","observed_orcids":["https://orcid.org/0000-0003-4530-8706"]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Luciano Saso","raw_affiliation_strings":["Department of Cardiovascular, Endocrine-Metabolic Diseases, and Aging, Italian National Institute of Health, 00161 Rome, Italy","Department of Physiology and Pharmacology \u201cVittorio Erspamer\u201d, Sapienza University of Rome, 00185 Rome, Italy"],"raw_orcid":"https://orcid.org/0000-0003-4530-8706","affiliations":[{"raw_affiliation_string":"Department of Cardiovascular, Endocrine-Metabolic Diseases, and Aging, Italian National Institute of Health, 00161 Rome, Italy","institution_ids":["https://openalex.org/I27897274"]},{"raw_affiliation_string":"Department of Physiology and Pharmacology \u201cVittorio Erspamer\u201d, Sapienza University of Rome, 00185 Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5012749696","https://openalex.org/A5059404446","https://openalex.org/A5065222117"],"corresponding_institution_ids":["https://openalex.org/I27897274","https://openalex.org/I4210086961","https://openalex.org/I861853513"],"apc_list":{"value":2200,"currency":"CHF","value_usd":2303},"apc_paid":{"value":2200,"currency":"CHF","value_usd":2303},"fwci":0.857,"has_fulltext":true,"cited_by_count":41,"citation_normalized_percentile":{"value":0.67960352,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"10","issue":"9","first_page":"2088","last_page":"2088"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.7329000234603882,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.7329000234603882,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.22280000150203705,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.007899999618530273,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ribosome-biogenesis","display_name":"ribosome biogenesis","score":0.8379999995231628},{"id":"https://openalex.org/keywords/ribosomal-proteins","display_name":"ribosomal proteins","score":0.8730000257492065},{"id":"https://openalex.org/keywords/tumor-cell-proliferation","display_name":"tumor cell proliferation","score":0.8029999732971191},{"id":"https://openalex.org/keywords/oncoprotein","display_name":"oncoprotein","score":0.9269999861717224},{"id":"https://openalex.org/keywords/ribosomal-protein-mutations","display_name":"ribosomal protein mutations","score":0.6980000138282776},{"id":"https://openalex.org/keywords/protein-synthesis","display_name":"protein synthesis","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C2779419633","wikidata":"https://www.wikidata.org/wiki/Q7322423","display_name":"Ribosome biogenesis","level":5,"score":0.931896984577179},{"id":"https://openalex.org/C88478588","wikidata":"https://www.wikidata.org/wiki/Q42244","display_name":"Ribosome","level":4,"score":0.8349727392196655},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6106432676315308},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.5908045768737793},{"id":"https://openalex.org/C38062823","wikidata":"https://www.wikidata.org/wiki/Q3408228","display_name":"Ribosomal protein","level":5,"score":0.574870765209198},{"id":"https://openalex.org/C3675279","wikidata":"https://www.wikidata.org/wiki/Q211935","display_name":"Protein biosynthesis","level":2,"score":0.5412213206291199},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5287387371063232},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.5060071349143982},{"id":"https://openalex.org/C67905577","wikidata":"https://www.wikidata.org/wiki/Q215980","display_name":"Ribosomal RNA","level":3,"score":0.4670487940311432},{"id":"https://openalex.org/C204241405","wikidata":"https://www.wikidata.org/wiki/Q461499","display_name":"Transformation (genetics)","level":3,"score":0.4394776523113251},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4352002739906311},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.41360506415367126},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3841235637664795},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.38310879468917847},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.24224397540092468},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.2167050540447235},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19358617067337036},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11288759112358093}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/biomedicines10092088","doi":"https://doi.org/10.3390/biomedicines10092088","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biomedicines10092088","pdf_url":"https://www.mdpi.com/2227-9059/10/9/2088/pdf?version=1662543063","source":{"id":"https://openalex.org/S2737005842","display_name":"Biomedicines","issn_l":"2227-9059","issn":["2227-9059"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"journal-article"},{"id":"pmid:36140189","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36140189","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9495564","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9495564/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"Text"},{"id":"pmh:oai:iris.uniroma1.it:11573/1654066","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11573/1654066","pdf_url":"https://iris.uniroma1.it/bitstream/11573/1654066/1/Temaj_Ribosome_2022.pdf.pdf","source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:a1f97a94b58049e28327427ca3b58927","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a1f97a94b58049e28327427ca3b58927","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biomedicines, Vol 10, Iss 9, p 2088 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/biomedicines10092088","doi":"https://doi.org/10.3390/biomedicines10092088","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biomedicines10092088","pdf_url":"https://www.mdpi.com/2227-9059/10/9/2088/pdf?version=1662543063","source":{"id":"https://openalex.org/S2737005842","display_name":"Biomedicines","issn_l":"2227-9059","issn":["2227-9059"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicines","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4293414971.pdf","grobid_xml":"https://content.openalex.org/works/W4293414971.grobid-xml"},"referenced_works_count":222,"referenced_works":["https://openalex.org/W886534176","https://openalex.org/W1501966284","https://openalex.org/W1557288216","https://openalex.org/W1582807345","https://openalex.org/W1707356941","https://openalex.org/W1943036748","https://openalex.org/W1963434741","https://openalex.org/W1965244636","https://openalex.org/W1965611273","https://openalex.org/W1966110930","https://openalex.org/W1968560149","https://openalex.org/W1974391793","https://openalex.org/W1977131067","https://openalex.org/W1980373840","https://openalex.org/W1981988708","https://openalex.org/W1985821091","https://openalex.org/W1986038921","https://openalex.org/W1986304086","https://openalex.org/W1986550373","https://openalex.org/W1987650787","https://openalex.org/W1989825144","https://openalex.org/W1990981389","https://openalex.org/W2000773591","https://openalex.org/W2003023964","https://openalex.org/W2005447120","https://openalex.org/W2006955217","https://openalex.org/W2008044201","https://openalex.org/W2008121312","https://openalex.org/W2013566223","https://openalex.org/W2013779315","https://openalex.org/W2018305417","https://openalex.org/W2021764678","https://openalex.org/W2024133044","https://openalex.org/W2029912515","https://openalex.org/W2032592004","https://openalex.org/W2033172050","https://openalex.org/W2034199961","https://openalex.org/W2036278037","https://openalex.org/W2037235549","https://openalex.org/W2039094077","https://openalex.org/W2039143660","https://openalex.org/W2039171339","https://openalex.org/W2039196311","https://openalex.org/W2040483206","https://openalex.org/W2041051519","https://openalex.org/W2042340784","https://openalex.org/W2042697095","https://openalex.org/W2049070379","https://openalex.org/W2054424756","https://openalex.org/W2056589536","https://openalex.org/W2057837559","https://openalex.org/W2062060771","https://openalex.org/W2066272205","https://openalex.org/W2067330050","https://openalex.org/W2070887804","https://openalex.org/W2070895376","https://openalex.org/W2071849521","https://openalex.org/W2072980043","https://openalex.org/W2073367697","https://openalex.org/W2073893672","https://openalex.org/W2075492832","https://openalex.org/W2076263063","https://openalex.org/W2076826746","https://openalex.org/W2079819818","https://openalex.org/W2083309296","https://openalex.org/W2083349873","https://openalex.org/W2083759095","https://openalex.org/W2084491230","https://openalex.org/W2084697906","https://openalex.org/W2085974260","https://openalex.org/W2089716875","https://openalex.org/W2092389309","https://openalex.org/W2092594973","https://openalex.org/W2097580481","https://openalex.org/W2097857247","https://openalex.org/W2097932770","https://openalex.org/W2100893053","https://openalex.org/W2101309212","https://openalex.org/W2103482257","https://openalex.org/W2104276827","https://openalex.org/W2108612226","https://openalex.org/W2110803333","https://openalex.org/W2111962997","https://openalex.org/W2113934702","https://openalex.org/W2116777154","https://openalex.org/W2119606554","https://openalex.org/W2119754956","https://openalex.org/W2120344444","https://openalex.org/W2121413649","https://openalex.org/W2122862521","https://openalex.org/W2123282517","https://openalex.org/W2123320389","https://openalex.org/W2124552631","https://openalex.org/W2126238482","https://openalex.org/W2126602665","https://openalex.org/W2129104457","https://openalex.org/W2130317021","https://openalex.org/W2134052560","https://openalex.org/W2134762011","https://openalex.org/W2137656352","https://openalex.org/W2146330762","https://openalex.org/W2150241164","https://openalex.org/W2151510603","https://openalex.org/W2153839483","https://openalex.org/W2157343715","https://openalex.org/W2158166500","https://openalex.org/W2161497461","https://openalex.org/W2161594264","https://openalex.org/W2162778008","https://openalex.org/W2165341580","https://openalex.org/W2166117980","https://openalex.org/W2166359808","https://openalex.org/W2168727504","https://openalex.org/W2169544896","https://openalex.org/W2169805130","https://openalex.org/W2171323620","https://openalex.org/W2188023805","https://openalex.org/W2194436977","https://openalex.org/W2268160049","https://openalex.org/W2270394595","https://openalex.org/W2274335785","https://openalex.org/W2312506538","https://openalex.org/W2328445716","https://openalex.org/W2332884175","https://openalex.org/W2346168689","https://openalex.org/W2402047081","https://openalex.org/W2408754178","https://openalex.org/W2409155655","https://openalex.org/W2413630402","https://openalex.org/W2422136427","https://openalex.org/W2427872948","https://openalex.org/W2474052246","https://openalex.org/W2476271072","https://openalex.org/W2515771603","https://openalex.org/W2526133414","https://openalex.org/W2526398031","https://openalex.org/W2528762358","https://openalex.org/W2528981561","https://openalex.org/W2549858084","https://openalex.org/W2552572842","https://openalex.org/W2553294121","https://openalex.org/W2557881641","https://openalex.org/W2588267243","https://openalex.org/W2589565256","https://openalex.org/W2591905283","https://openalex.org/W2593857065","https://openalex.org/W2601524907","https://openalex.org/W2602200537","https://openalex.org/W2608206217","https://openalex.org/W2625763766","https://openalex.org/W2729733223","https://openalex.org/W2733572144","https://openalex.org/W2734840967","https://openalex.org/W2742294482","https://openalex.org/W2743024582","https://openalex.org/W2761463268","https://openalex.org/W2762658812","https://openalex.org/W2762801938","https://openalex.org/W2763441547","https://openalex.org/W2768377421","https://openalex.org/W2769453731","https://openalex.org/W2773619385","https://openalex.org/W2776078247","https://openalex.org/W2791833290","https://openalex.org/W2793518816","https://openalex.org/W2795073885","https://openalex.org/W2795455346","https://openalex.org/W2799333219","https://openalex.org/W2806744614","https://openalex.org/W2808254973","https://openalex.org/W2811111314","https://openalex.org/W2883836317","https://openalex.org/W2886956635","https://openalex.org/W2891896215","https://openalex.org/W2892147349","https://openalex.org/W2892227983","https://openalex.org/W2894329930","https://openalex.org/W2901716885","https://openalex.org/W2903989525","https://openalex.org/W2910848742","https://openalex.org/W2913415147","https://openalex.org/W2914771869","https://openalex.org/W2915304621","https://openalex.org/W2916349681","https://openalex.org/W2921996673","https://openalex.org/W2943797269","https://openalex.org/W2944290286","https://openalex.org/W2944819910","https://openalex.org/W2952108907","https://openalex.org/W2956127026","https://openalex.org/W2973384337","https://openalex.org/W2979245704","https://openalex.org/W2982755113","https://openalex.org/W2999892513","https://openalex.org/W3002480029","https://openalex.org/W3009491962","https://openalex.org/W3014643401","https://openalex.org/W3024976620","https://openalex.org/W3030498015","https://openalex.org/W3096523604","https://openalex.org/W3132516110","https://openalex.org/W3133626746","https://openalex.org/W3134241172","https://openalex.org/W3134549517","https://openalex.org/W3139023757","https://openalex.org/W3139397984","https://openalex.org/W3147216348","https://openalex.org/W3149612306","https://openalex.org/W3157874904","https://openalex.org/W3163997881","https://openalex.org/W3165717732","https://openalex.org/W3168084797","https://openalex.org/W3168421815","https://openalex.org/W3173324977","https://openalex.org/W3183313475","https://openalex.org/W3211664393","https://openalex.org/W4254122983","https://openalex.org/W4256485542","https://openalex.org/W4295122766","https://openalex.org/W6730720466","https://openalex.org/W6745515253","https://openalex.org/W6777687024"],"related_works":["https://openalex.org/W3087133080","https://openalex.org/W2901745232","https://openalex.org/W4302013545","https://openalex.org/W2766026397","https://openalex.org/W2773619385","https://openalex.org/W3103660847","https://openalex.org/W4283832572","https://openalex.org/W1953527354","https://openalex.org/W3009491962","https://openalex.org/W3198338615"],"abstract_inverted_index":{"The":[0,48],"human":[1],"ribosomes":[2],"are":[3,35,59],"the":[4,68],"cellular":[5],"machines":[6],"that":[7,73],"participate":[8],"in":[9,40],"protein":[10],"synthesis,":[11],"which":[12],"is":[13,23],"deeply":[14],"affected":[15],"during":[16],"cancer":[17,27,79],"transformation":[18],"by":[19],"different":[20,71],"oncoproteins":[21],"and":[22,30,43,56,78],"shown":[24],"to":[25,61],"provide":[26],"cell":[28,80],"proliferation":[29],"therefore":[31],"biomass.":[32],"Cancer":[33],"diseases":[34],"associated":[36],"with":[37],"an":[38,51],"increase":[39],"ribosome":[41,49,76],"biogenesis":[42,77],"mutation":[44],"of":[45,70],"ribosomal":[46],"proteins.":[47],"represents":[50],"attractive":[52],"anti-cancer":[53],"therapy":[54],"target":[55],"several":[57],"strategies":[58],"used":[60],"identify":[62],"specific":[63],"drugs.":[64],"Here":[65],"we":[66],"review":[67],"role":[69],"drugs":[72],"may":[74],"decrease":[75],"proliferation.":[81]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-08-29T00:00:00"}